Search

Comprehensive Summary: Collective syntheses of A. baumannii CPS K43, K47 and K88 repeating units have been accomplished via a new α‐glycosylation method with GlcN3 as donors, which features: 1) mild reaction conditions, 2) good to high yields, 3) excellent stereoselectivities. The synthetic route also highlights an orthogonal one‐pot coupling strategy on the basis of glycosyl ortho‐(1‐phenylvinyl)benzoates for stereoselective constructions of both 1,2‐trans and 1,2‐cis glycosidic bonds, precluding the issues of aglycone transfer. [ABSTRACT FROM AUTHOR]

The solar photovoltaic industry has developed rapidly in recent years. Accurate diagnosis of the location and type of PV module faults can improve the efficiency of operation and maintenance personnel. In this paper, a deep learning diagnostic model based on convolutional neural networks-long short term memory(CNN-LSTM) is proposed, which can be used to complete the detection task. In this paper, a fault classification method based on current performance is established. The algorithm firstly designs a feature extraction algorithm based on the layout characteristics of the PV array, and extracts the lateral and vertical features of the PV array current to obtain the spatial and temporal characteristics. The CNN network further extracts the lateral features and compresses the vertical features to solve the problem of single feature types and slow training. Finally, the LSTM neural network is used to complete the fault diagnosis of the PV modules.

Lanthanide ion (Ln3+)‐doped halide double perovskites (DPs) have evoked tremendous interest due to their unique optical properties. However, Ln3+ ions in these DPs still suffer from weak emissions due to their parity‐forbidden 4f–4f electronic transitions. Herein, the local electronic structure of Ln3+‐doped Cs2NaInCl6 DPs is unveiled. Benefiting from the localized electrons of [YbCl6]3− octahedron in Cs2NaInCl6 DPs, an efficient strategy of Cl−‐Yb3+ charge transfer sensitization is proposed to obtain intense near‐infrared (NIR) luminescence of Ln3+. NIR photoluminescence (PL) quantum yield (QY) up to 39.4% of Yb3+ in Cs2NaInCl6 is achieved, which is more than three orders of magnitude higher than that (0.1%) in the well‐established Cs2AgInCl6 via conventional self‐trapped excitons sensitization. Density functional theory calculation and Bader charge analysis indicate that the [YbCl6]3− octahedron is strongly localized in Cs2NaInCl6:Yb3+, which facilitates the Cl−‐Yb3+ charge transfer process. The Cl−‐Yb3+ charge transfer sensitization mechanism in Cs2NaInCl6:Yb3+ is further verified by temperature‐dependent steady‐state and transient PL spectra. Furthermore, efficient NIR emission of Er3+ with the NIR PLQY of 7.9% via the Cl−‐Yb3+ charge transfer sensitization is realized. These findings provide fundamental insights into the optical manipulation of Ln3+‐doped halide DPs, thus laying a foundation for the future design of efficient NIR‐emitting DPs. [ABSTRACT FROM AUTHOR]

Comprehensive Summary: Collective syntheses of A. baumannii CPS K43, K47 and K88 repeating units have been accomplished via a new α‐glycosylation method with GlcN3 as donors, which features: 1) mild reaction conditions, 2) good to high yields, 3) excellent stereoselectivities. The synthetic route also highlights an orthogonal one‐pot coupling strategy on the basis of glycosyl ortho‐(1‐phenylvinyl)benzoates for stereoselective constructions of both 1,2‐trans and 1,2‐cis glycosidic bonds, precluding the issues of aglycone transfer. [ABSTRACT FROM AUTHOR]

Herein, we report the design of novel ultraviolet luminescent CsPbCl3 nanocrystals (NCs) with the emission peak at 381 nm through doping of cadmium ions. Subsequently, a surface passivation strategy with CdCl2 is adopted to improve their photoluminescence quantum yield (PLQY) with the maximum value of 60.5 %, which is 67 times higher than that of the pristine counterparts. The PLQY of the surface passivated NCs remains over 50 % after one week while the pristine NCs show negligible emission. By virtue of density functional theory calculations, we reveal that the higher PLQY and better stability after surface passivation may result from the significant elimination of surface chloride vacancy (VCl) defects. These findings provide fundamental insights into the optical manipulation of metal ion‐doped CsPbCl3 NCs. [ABSTRACT FROM AUTHOR]

Abstract Background Salt stress hinders the growth of plants and reduces crop production worldwide. However, different plant species might possess different adaptive mechanisms to mitigate salt stress. We conducted a detailed pathway analysis of transcriptional dynamics in the roots of Medicago truncatula seedlings under salt stress and selected a transcription factor gene, MtCBF4, for experimental validation. Results A microarray experiment was conducted using root samples collected 6, 24, and 48 h after application of 180 mM NaCl. Analysis of 11 statistically significant expression profiles revealed different behaviors between primary and secondary metabolism pathways in response to external stress. Secondary metabolism that helps to maintain osmotic balance was induced. One of the highly induced transcription factor genes was successfully cloned, and was named MtCBF4. Phylogenetic analysis revealed that MtCBF4, which belongs to the AP2-EREBP transcription factor family, is a novel member of the CBF transcription factor in M. truncatula. MtCBF4 is shown to be a nuclear-localized protein. Expression of MtCBF4 in M. truncatula was induced by most of the abiotic stresses, including salt, drought, cold, and abscisic acid, suggesting crosstalk between these abiotic stresses. Transgenic Arabidopsis over-expressing MtCBF4 enhanced tolerance to drought and salt stress, and activated expression of downstream genes that contain DRE elements. Over-expression of MtCBF4 in M. truncatula also enhanced salt tolerance and induced expression level of corresponding downstream genes. Conclusion Comprehensive transcriptomic analysis revealed complex mechanisms exist in plants in response to salt stress. The novel transcription factor gene MtCBF4 identified here played an important role in response to abiotic stresses, indicating that it might be a good candidate gene for genetic improvement to produce stress-tolerant plants.

Inside Cover: Modular Synthesis of a Tridecasaccharide Motif of Bacteroides vulgatus Lipopolysaccharides against Inflammatory Bowel Diseases through an Orthogonal One-Pot Glycosylation Strategy (Angew. Keywords: Anti-Inflammatory Activity; Lipopolysaccharides; Oligosaccharide Synthesis; Orthogonal One-Pot Glycosylation; Stereoselectivity EN Anti-Inflammatory Activity Lipopolysaccharides Oligosaccharide Synthesis Orthogonal One-Pot Glycosylation Stereoselectivity 1 1 1 05/16/23 20230522 NES 230522 B Lipopolysaccharides b from I Bacteroides vulgatus i represent interesting targets for the treatment of inflammatory bowel diseases. Anti-Inflammatory Activity, Lipopolysaccharides, Oligosaccharide Synthesis, Orthogonal One-Pot Glycosylation, Stereoselectivity. [Extracted from the article]

In their Research Article (e202301351), Guozhi Xiao and co-workers accomplished the first synthesis of a tridecasaccharide motif from I Bacteroides vulgatus i lipopolysaccharides by a strategy involving orthogonal one-pot glycosylation reactions based on glycosyl I ortho i -(1-phenylvinyl)benzoates, which avoided issues such as aglycone transfer and the unpleasant odor of thioglycoside-based orthogonal one-pot glycosylation. Anti-Inflammatory Activity, Lipopolysaccharides, Oligosaccharide Synthesis, Orthogonal One-Pot Glycosylation, Stereoselectivity Keywords: Anti-Inflammatory Activity; Lipopolysaccharides; Oligosaccharide Synthesis; Orthogonal One-Pot Glycosylation; Stereoselectivity EN Anti-Inflammatory Activity Lipopolysaccharides Oligosaccharide Synthesis Orthogonal One-Pot Glycosylation Stereoselectivity 1 1 1 05/16/23 20230522 NES 230522 B Lipopolysaccharides b from I Bacteroides vulgatus i represent interesting targets for the treatment of inflammatory bowel diseases. [Extracted from the article]

Mucin-related tumor-associated carbohydrate antigens (TACAs) are important and interesting targets for cancer vaccine therapy. However, efficient access to a library of mucin-related TACAs remains a challenging task. One of the key issues is the challenging construction of α-GalNAc linkages. Here, we report highly stereoselective α-glycosylation with GalN 3 N -phenyl trifluoroacetimidate donors, which features excellent yields, outstanding stereoselectivities, broad substrate scope and mild reaction conditions. This method is successfully applied to highly stereoselective synthesis of GalN 3 -α- O -Ser, which served as the common intermediate for collective synthesis of a wide range of TACAs including T N antigen, ST N antigen, 2,6 STF antigen, 2,3 STF antigen, glycophorin and cores 1-8 mucin-type O -glycans. In particular, the rationale for this highly stereoselective α-glycosylation is provided for the first time using DFT calculations and mechanistic studies, highlighting the crucial roles of reagent combinations (TMSI and Ph 3 PO) and the H-bonding directing effect of the N 3 group., Competing Interests: The authors declare no competing financial interests., (This journal is © The Royal Society of Chemistry.)