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In this study, cellulose films loaded with different concentrations (0%, 0.1%, 0.5% and 1%) of curcumin (C-Cux-F) having good mechanical properties, water resistance, photosensitive antibacterial properties, and high oxygen-barrier performance were successfully prepared. Due to its strong interaction with the cellulose chain, curcumin could significantly improve the mechanical properties and water resistance of cellulose film. The doping level of curcumin significantly affected the oxygen permeability of cellulose film (P < 0.05). The oxygen permeability of the film gradually decreased with the increase in curcumin level. The oxygen permeability of the films loaded with 0%, 0.1%, 0.5%, and 1% curcumin was approximately (29.71 ± 1.66), (4.79 ± 0.13), (3.52 ± 0.45), and (0.90 ± 0.09) cm3/(m2·d) at room temperature (23 ℃), respectively. The addition of curcumin in the range of 0% to 0.5% significantly reduced the moisture permeability of cellulose film due to the enhancement of intermolecular forces (P < 0.05). Curcumin-loaded cellulose film exhibited a good photosensitive antibacterial effect against S. aureus, which increased with the extension in light exposure time. This is probably ascribed to the fact that photosensitization of curcumin generates singlet oxygen. After white light exposure for 10 and 20 min at an intensity of 60 mW/cm2, the inhibitory activity of 1% curcumin-loaded cellulose film (C-Cu1-F) against S. aureus was (61.00 ± 1.73)% and (91.67 ± 1.53)% , respectively. In the preservation of fresh chilled pork, C-Cu1-F could significantly inhibit the production of total volatile basic nitrogen (TVB-N), and reduce the total bacterial count (P < 0.05), implying a significant inhibitory effect on the growth of microorganisms and the production of biogenic amines. Therefore, curcumin-loaded cellulose film not only showed excellent mechanical and antibacterial properties, but also had a preservation effect on fresh pork.

The compound rotor system of a mechanically rectified permanent magnet generator is the key structure to realize the rectification function. The dynamics of the compound rotor system under bidirectional input conditions are studied to analyze the vibration deformation degree of each component of the rotor system and to ensure the uniform distribution of the shunt load of each planetary gear. In this paper, based on the theory of concentrated mass parameters, a dynamic model of the compound rotor system under the condition of bidirectional input is established. The model is solved with the Runge-Kutta numerical integration method. The dynamics of each component under the condition of bidirectional input are obtained. The results show that the oscillations of torsional displacement of each component of the compound rotor system are all about 25 μm, and the standard deviations of the meshing forces of each planetary shunt are all about 200 N during the two-way input, indicating that the vibration degree of the compound rotor system is similar; The load sharing coefficient of meshing forces decreases obviously with the increase of input torque and tends to be gentle when the torque reaches 500 N·m. Therefore, increasing the input torque can improve the dynamic meshing force and load sharing performance, so that the compound rotor system can obtain better dynamic performance under the bidirectional input condition. The research results are of great significance for the vibration and noise reduction and reliable operation of the permanent magnet generator.

In order to explore the effects of different combinations of spice essential oils on the quality and safety of air-dried catfish sausages, sausages were prepared from marinated catfish surimi added with a 1:1 (m/m) blend of clove and star anise (CA), clove and perilla (CP), star anise and perilla (AP) or clove, star anise and perilla essential oil (CAP) at 0.03% or none as a control. Moisture content, water activity (aw), pH, color difference, thiobarbituric acid reactive substance (TBARS) value, biological amine content, N-nitrosamine content, and microbial load were measured. Microbial community structure was analyzed by 16S rDNA high-throughput sequencing. The results showed that the moisture content of the AP group was 27.13%, and the aw value was 0.765. The L* and a* values of the CA group were high, indicating typical characteristics of air-dried sausages. The pH of the four treatment groups was higher than that of the control group, and followed the descending order of CAP > AP > CA > CP. There was no significant difference in the inhibition of fat oxidation among different essential oil combinations (P > 0.05), but the TBARS value of air-dried sausages was significantly reduced by all combinations (P < 0.05). The contents of biogenic amine and N-nitrosamine in the AP group were low. The total number of bacteria, and the number of Enterobacteriaceae and Aeromonas were significantly lower in the AP group than in the control group (P < 0.05). High-throughput sequencing results showed low species richness in the AP and CAP groups and low relative abundance of pathogenic bacteria in the AP group. Overall analysis showed that AP was superior to the other groups in improving the quality and safety of air-dried catfish sausages.

Strategic evaluation is the key link of military strategic system and capacity building. Selecting and evaluating the system construction scheme can optimize strategic decision-making and improve strategic management level to a certain extent. This paper constructs an intelligent selection analysis framework of "prospect cost" system construction scheme based on MATE, and uses NSGA-Ⅱ intelligent optimization algorithm to find the Pareto front of alternative scheme in multi-dimensional tradeoff space, which improves the problem of large data volume. Taking a joint operation system as an example, the effectiveness of the proposed method is verified, providing theoretical support for the optimization and evaluation of system construction scheme.

To summarized the prevention and control of nosocomial infection in a certain endoscopy center under the management of COVID-19 with measures against Class B infectious diseases. According to the hospital infection prevention and control requirements and related documents, combined with the actual situation of the clinical diagnosis and treatment in the endoscopy center, the infection control measures were formulated and implemented from the aspects of the management of the endoscopy center and the management and protection of the endoscopy staff and patients. From January 20, 2023 to March 20, 2023, 98 cases of digestive endoscopy were completed in the endoscopy center. No nosocomial infection occurred. Under the management of COVID-19 with measures against Class B infectious diseases, efforts should be made to enhance the emergency management and implementation of preoperative screening, therapeutic indications and diagnosis condition for digestive endoscopy. Strengthened protection of medical staff, cleaning and disinfection specification and establishment of the three-zone two-channel isolation wards are necessary to reduce the incidence of nosocomial infection in the endoscopy center. (总结新型冠状病毒感染“乙类乙管”下医院内窥镜中心感染防控与实践体会。根据医院感控要求及相关文件内容, 结合医院内窥镜中心临床诊疗的实际情况, 分别从内镜中心的管理及内镜工作人员和患者的管理与防护等方面制定和落实感控措施, 并进行效果评价。2023年1月20日—2023年3月20日, 内窥镜中心共完成消化内镜诊疗98例, 无院内感染发生。新型冠状病毒感染“乙类乙管”下, 消化内镜中心必须做好应急管理工作, 采取合理有效的措施, 切实做好术前患者各项筛查与管理工作, 严格把握消化内镜操作的适应证与诊疗条件, 做好内镜工作人员管理与防护工作, 严格遵守内镜室的洗消规范, 构建内镜室“三区两通道”隔离布局, 降低院内感染风险。)

With the advancement of contemporary technology, there is an increasing demand for sophisticated tone libraries in intelligent and digital pianos. This paper introduces a virtual piano system based on timbre simulation. Drawing upon the articulation principles of the piano, a mathematical model is formulated to derive the equation governing string vibrations. This equation facilitates a comprehensive analysis of the components constituting piano timbre and establishes a model for synthesizing these timbres using a frequency envelope algorithm. The short-time Fourier transform (STFT) is utilized to extract features from the synthesized timbre and to accomplish its digital simulation. Subsequently, the integration of the piano’s timbre features with computer programming facilitates the comprehensive design of the virtual piano system. Performance testing and evaluation of the system reveal promising results: the detection rate for each musical piece exceeds 90%, with an average detection rate of 94.81% across ten pieces and an average deviation (Mean-D) of 3.35 in the scoring of 100 music samples. This research contributes to the flexibility in timbre editing, enhances the expressiveness of intelligent and digital pianos, and aims to elevate the music industry to new heights.

In this paper, we use computer techniques to extract the features of each convolutional layer of CNN, analyze the feature variations of different depth convolutions, and propose a new network framework to improve the head pose estimation task performance by combining the task characteristics of head pose estimation. Multi-scale feature information fusion is the basis of the proposed head pose estimation method (IRHP-Net), which consists of a feature extraction module and a multi-scale feature information fusion module. In the smart classroom learning environment, the algorithm is used to identify students’ attention areas and construct the distraction index and threshold parameters to determine the inattentive state and provide relevant teaching measures. Smart classroom teaching resulted in a 39.69% increase in students’ attention, as shown in the results. Students in the traditional teaching mode showed a 16.7% lower level of learning engagement. A 17.24% increase in academic performance was also a result of the increase in attention and learning engagement.

BackgroundDespite the increasing popularity of mHealth, little evidence indicates that they can improve health outcomes. Mobile health interventions (mHealth) have been shown as an attractive approach for health-care systems with limited resources. To determine whether mHealth would reduce blood pressure, promote weight loss, and improve hypertension compliance, self-efficacy and life quality in individuals with hypertension living in low-resource rural settings in Hubei, China.MethodsIn this parallel-group, randomized controlled trial, we recruited individuals from health-care centers, home visits, and community centers in low-resource rural settings in Hubei, China. Of 200 participants who were screened, 148 completed consent, met inclusion criteria, and were randomly assigned in a ratio of 1:1 to control or intervention. Intervention group participants were instructed to use the Monitoring Wearable Device and download a Smartphone Application, which includes reminder alerts, adherence reports, medical instruction and optional family support. Changes in the index of Cardiovascular health risk factors from baseline to end of follow-up. Secondary outcomes were change in hypertension compliance, self-efficacy and life quality at 12 weeks.ResultsParticipants (n = 134; 66 in the intervention group and 68 controls) had a mean age of 61.73 years, 61.94% were male. After 12 weeks, the mean (SD) systolic blood pressure decreased by 8.52 (19.73) mm Hg in the intervention group and by 1.25 (12.47) mm Hg in the control group (between-group difference, −7.265 mm Hg; 95% CI, −12.89 to −1.64 mm Hg; P = 0.012), While, there was no difference in the change in diastolic blood pressure between the two groups (between-group difference, −0.41 mm Hg; 95% CI, −3.56 to 2.74 mm Hg; P = 0.797). After 12 weeks of follow-up, the mean (SD) hypertension compliance increased by 7.35 (7.31) in the intervention group and by 3.01 (4.92) in the control group (between-group difference, 4.334; 95% CI, 2.21 to −6.46; P < 0.01), the mean (SD) hypertension compliance increased by 12.89 (11.95) in the intervention group and by 5.43 (10.54) in the control group (between-group difference, 7.47; 95% CI, 3.62 to 11.31; P < 0.01), the mean (SD) physical health increased by 12.21 (10.77) in the intervention group and by 1.54 (7.18) in the control group (between-group difference, 10.66; 95% CI, 7.54–13.78; P < 0.01), the mean (SD) mental health increased by 13.17 (9.25) in the intervention group and by 2.55 (5.99) in the control group (between-group difference, 10.93; 95% CI, 7.74 to 14.12; P < 0.01).ConclusionsAmong participants with uncontrolled hypertension, individuals randomized to use a monitoring wearable device with a smartphone application had a significant improvement in self-reported hypertension compliance, self-efficacy, life quality, weight loss and diastolic blood pressure, but no change in systolic blood pressure compared with controls.

ObjectivesThe association between coffee consumption and the risk of metabolic syndrome (MetS) remains inconsistent. The aim of this study was to evaluate the association between coffee intake and components of MetS.MethodA cross-sectional survey including 1,719 adults was conducted in Guangdong, China. Data on age, gender, education level, marriage status, body mass index (BMI), current smoking and drinking status and breakfast habit, coffee consumption type, and daily servings were derived based on 2-day, 24-h recall. MetS were assessed according to the International Diabetes Federation definition. Multivariable logistic regression was conducted to examine the association between the coffee consumption type, daily servings, and the components of MetS.ResultsRegardless of the coffee type, compared with non-coffee consumers, coffee consumers had higher odds ratios (ORs) of the elevated fasting blood glucose (FBG) in both men [OR: 3.590; 95% confidence intervals (CI): 2.891–4.457] and women (OR: 3.590; 95% CI: 2.891–4.457). In women, the risk of elevated blood pressure (BP) was 0.553 times (OR: 0.553; 95% CI: 0.372–0.821, P = 0.004) for people who drank total coffee > 1 serving/day than for non-coffee drinkers.ConclusionIn conclusion, regardless of type, coffee intake is associated with an increased prevalence of FBG in both men and women, but has a protective effect on hypertension only in women.

RNA binding proteins (RBPs) play a key role in genome regulation. Here we report the post-transcript regulation of IGF2BP3, which belongs to the insulin-like growth factor 2 mRNA binding protein family. We used iRIP-seq and RNA-seq to analyze the transcript regulation and alternative splicing on IGF2BP3 treated with overexpression cells and control. Overexpressed IGF2BP3 has broadly increased genes expression which involved in G-protein coupled receptor signaling pathway, positive regulation of cell proliferation, and signal transduction. IGF2BP3 regulated alternative splicing of multiple genes mainly clustered at response to hypoxia, negative regulation of transcription, and embryonic development. This study first provides alternative splicing analysis on transcription level of IGF2BP3 regulation, which laid the foundation for later research on IGF2BP3 critical functions.

The implementation of "the Belt and Road" initiative has further enhanced China’s economic openness and attracted more foreign direct investment (FDI). However, China is characterized by unbalanced economic development and distribution of resources in different regions. Therefore, analyzing the impact of FDI on economic openness of 18 provinces along "the Belt and Road" and developing the economies of these provinces more specifically have become an important issue. This paper uses factor analysis and DEA-Malmquist model to construct the economic openness of 18 provinces. FDI proxied by 5 measurements are selected to evaluate the impact of foreign direct investment on each province’s economic openness by using spatial econometric model. Empirical results find that FDI has a positive impact on the economic openness of the provinces along "the Belt and Road", and the surrounding provinces also have a significant role in promoting the economic openness of a province. But FDI has different impact on different regions with East Region exhibiting the most significant effect. FDI enhances economic openness mainly through registered capital of foreign-invested enterprises and total import and export of foreign-invested enterprises.

With the continuous development of globalization, China has been devoted to promoting the degree of openness. The implementation of “the Belt and Road” initiative brings huge development prospects for China’s OFDI. Utilizing a panel data set consisting of a total of 51 countries along the “the Belt and Road” from 2007 to 2016, this paper establishes an empirical model and examines the influencing factors of the location choice on China’s OFDI in “the Belt and Road” countries. This paper collects comprehensive country-level data of 51 countries along “the Belt and Road” with Python. The number of investment enterprises in the host country published by the Open Directory of Record Results of Overseas Investment Enterprises (Institutions) is used as the explanatory variable. This paper conducts Poisson’s regression to study the influencing factors of location choice. According to the empirical results, bilateral trade agreements can help reduce the difficulties that China may face with in investing and facilitate China to access the host country for investment. In addition, Chinese enterprises may invest in countries where the degree of governance is moderate based on the negative impact on China’s investment in “the Belt and Road” countries. Also, China may invest in countries where the natural resources are poor considering the degree of governance even though natural resources have a positive effect on investment. Furthermore, the level of infrastructure construction in the host country has a positive effect on China’s direct investment in countries along “the Belt and Road”. Besides, good political environment can attract Chinese enterprises to invest in countries along “the Belt and Road”.

The main contribution of this paper is to develop a method to determine the in situ stress on an engineering scale by modifying the elasto-static thermal stress model (Sheorey’s model). The suggested method, firstly, introduces correction factors for the local tectonism to reflect the stress distribution difference caused by local tectonic movements. The correction factors can be determined by the least-squares approach based on laboratory tests and local in situ stress measurements. Then, the rock elastic modulus is replaced by rock mass elastic modulus so as to show the effect of rock discontinuities on the in situ stress. Combining with elasticity theory, equations for estimating the major and minor horizontal stresses are obtained. It is possible to reach satisfactory accuracy for stress estimation. To show the feasibility of this method, it is applied to two deep tunnels in China to determine the in situ stress. Field tests, including in situ stress measurements by conventional hydraulic fracturing (HF) and rock mass modulus measurements using a rigid borehole jack (RBJ), are carried out. It is shown that the stress field in the two deep tunnels is dominated by horizontal tectonic movements. The major and minor horizontal stresses are estimated, respectively. Finally, the results are compared with those derived from the HF method. The calculated results in the two tunnels roughly coincide with the measured results with an average of 15% allowable discrepancy.