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Objective To describe the time point prevalence and distribution of all types of mental disorders in Hebei Province. Methods From October 2004 to March 2005, stratified multi-stage cluster randomization was used to identify 24,000 subjects ≥18 years of age in Hebei Province. An expanded version of the General Health Questionnaire (GHQ-12) was used to identify subgroups of subjects at high, moderate and low risk of having a mental disorder, then psychiatrists determined their diagnoses by administering a structured psychiatric examination (SCID) that employs Diagnostic and Statistical Manual of Mental Disorder (DSM-IV). Results (1) Twenty thousand seven hundred and sixteen subjects completed the screening. The overall time point rate of mental disorders was 16.24% (95% CI = 15.8–16.7%). Major depressive disorder (2.70%), unspecified anxiety disorders (2.51%) and dysthymic disorders (2.31%) occupied the preceding positions. The overall life-time prevalence of mental disorders was 18.51% (95% CI = 18.0–19.0%). Major depressive disorder (4.75%), alcohol dependence and abuse disorders (3.86%) and unspecified depressive disorder (2.55%) occupied the preceding positions. (2) The time point prevalence: the overall prevalence of mental disorders was higher in rural (16.65%) than in urban areas (14.43%) and obviously higher in women (16.79%) than in men (15.70%), P