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Recently, metal oxide semiconductors have attracted considerable interest in certain areas, such as displays. Applications of transparent metal oxide semiconductors in photosensors are also starting to develop owing to their high charge carrier concentration and mobility. By including a narrow bandgap material in the device, photoresponsivity can be improved, but it increases the number of fabrication steps. This paper suggests embedding an indium oxide thin film with graphene oxide (GO) photoactive particles in a single step from a mixed aqueous precursor solution by spin coating. The device performance was assessed as a function of the GO content. The device stability data showed that a higher GO content induced hole trapping under prolonged gate bias stress. Hole trapping at the In2O3/GO interface is important under illumination, where the trapping of the minor photogenerated carrier can improve the photocurrent via the photogating effect. The long-term trapping of holes in the n-type device also produces a persistent photocurrent, which makes the device respond to illumination like an artificial neuron. In addition to photodetection, the device applicability in binary logic circuits was also demonstrated via a load-type inverter. The phototransistor proposed in this study could achieve sensing, memory, and binary logic in the same device. [ABSTRACT FROM AUTHOR]

C26H24N3O3SAg, monoclinic, P21/c (no. 14), a = 13.1936(9) Å, b = 11.0544(7) Å, c = 16.3653(9) Å, β = 99.214(6)°, V = 2356.0(3) Å3, Z = 4, Rgt(F) = 0.0495, wRref(F2) = 0.1080, T = 293(2) K.

C25H29Ag2N5O9S, monoclinic, P21/m (no. 11), a = 8.5437(16) Å, b = 17.852(4) Å, c = 9.3335(13) Å, β = 101.380(16)°, V = 1395.6(5) Å3, Z = 2, Rgt(F) = 0.0271, wRref(F2) = 0.0653, T = 293(2) K.

C7H8Ag2N3O4S, triclinic, P1‾$‾{1}$ (no. 2), a = 7.3758(3) Å, b = 8.7361(4) Å, c = 9.2906(4) Å, α = 112.877(4)°, β = 90.054(4)°, γ = 102.568(4)°, V = 535.90(4) Å3, Z = 2, Rgt(F) = 0.0235, wRref(F2) = 0.0600, T = 293(2) K.

C12H18O8N4S2Ag2, monoclinic, P21/c (no. 14), a = 10.7841(10) Å, b = 8.0140(5) Å, c = 11.7220(11) Å, β = 117.278(11)°, V = 900.40(16) Å3, Z = 2, Rgt(F) = 0.0279, wRref(F2) = 0.0627, T = 293(2) K.

A method for radio frequency oxygen (O2) plasma-assisted treatment of indium zinc oxide (IZO) films with a multistacked architecture fabricated by a low-temperature (200 °C) solution process is investigated. We demonstrate that radio frequency O2 plasma-assisted posttreatment technology can improve the mobility and stability of IZO thin-film transistors (TFTs). The activity layers were formed by spin coating and subsequently thermally annealed at a low temperature of 200 °C, followed by O2-plasma posttreatment process, to form the O2 triggered multistacked architecture. The TFT devices plasma-treated for 3 min exhibit improved electrical characteristics, with a mobility of 7.09 ± 0.24 cm2/Vs, an ON OFF ratio of (1.21 ± 1.22) $\times 10^{{6}}$ , a threshold voltage of $-0.22\,\,\pm \,\,0.35$ V, and a subthreshold swing of 0.34 ± 0.02 V/dec. The improved results offered by the O2 plasma treatment led to a higher mobility and ON/ OFF ratio compared to sample device without this process. The successful fabrication of radio frequency O2 triggered multistacked architecture-based IZO TFTs showing the practical potential of high-performance low-temperature solution-processed preparation technology and radio frequency O2 plasma-assisted treatment for electrical device application. [ABSTRACT FROM AUTHOR]

C26H24N3O3SAg, monoclinic, P21/c (no. 14), a = 13.1936(9) Å, b = 11.0544(7) Å, c = 16.3653(9) Å, β = 99.214(6)°, V = 2356.0(3) Å3, Z = 4, Rgt(F) = 0.0495, wRref(F2) = 0.1080, T = 293(2) K. [ABSTRACT FROM AUTHOR]

C25H29Ag2N5O9S, monoclinic, P21/m (no. 11), a = 8.5437(16) Å, b = 17.852(4) Å, c = 9.3335(13) Å, β = 101.380(16)°, V = 1395.6(5) Å3, Z = 2, Rgt(F) = 0.0271, wRref(F2) = 0.0653, T = 293(2) K. [ABSTRACT FROM AUTHOR]

C12H18O8N4S2Ag2, monoclinic, P21/c (no. 14), a = 10.7841(10) Å, b = 8.0140(5) Å, c = 11.7220(11) Å, β = 117.278(11)°, V = 900.40(16) Å3, Z = 2, Rgt(F) = 0.0279, wRref(F2) = 0.0627, T = 293(2) K. [ABSTRACT FROM AUTHOR]

C12H18O8N4S2Ag2, monoclinic, P21/c (no. 14), a = 10.7841(10) Å, b = 8.0140(5) Å, c = 11.7220(11) Å, β = 117.278(11)°, V = 900.40(16) Å3, Z = 2, Rgt(F) = 0.0279, wRref(F2) = 0.0627, T = 293(2) K. [ABSTRACT FROM AUTHOR]

The robotic-assisted percutaneous coronary intervention is an emerging technology with great potential to solve the shortcomings of existing treatments. However, the current robotic systems can not manipulate two guidewires or ballons/stents simultaneously for coronary bifurcation lesions. This paper presents VasCure, a novel bio-inspired vascular robotic system, to deliver two guidewires and stents into the main branch and side branch of bifurcation lesions in sequence. The system is designed in master-slave architecture to reduce occupational hazards of radiation exposure and orthopedic injury to interventional surgeons. The slave delivery device has one active roller and two passive rollers to manipulate two interventional devices. The performance of the VasCure was verified by in vitro and in vivo animal experiments. In vitro results showed the robotic system has good accuracy to deliver guidewires and the maximum error is 0.38mm. In an animal experiment, the interventional surgeon delivered two guidewires and balloons to the left circumflex branch and the left anterior descending branch of the pig, which confirmed the feasibility of the vascular robotic system.

Percutaneous coronary intervention (PCI) has gradually become the most common treatment of coronary artery disease (CAD) in clinical practice due to its advantages of small trauma and quick recovery. However, the availability of hospitals with cardiac catheterization facilities and trained interventionalists is extremely limited in remote and underdeveloped areas. Remote vascular robotic system can assist interventionalists to complete operations precisely, and reduce occupational health hazards occurrence. In this paper, a bionic remote vascular robot is introduced in detail from three parts: mechanism, communication architecture, and controller model. Firstly, human finger-like mechanisms in vascular robot enable the interventionalists to advance, retract and rotate the guidewires or balloons. Secondly, a 5G-based communication system is built to satisfy the end-to-end requirements of strong data transmission and packet priority setting in remote robot control. Thirdly, a generalized predictive controller (GPC) is developed to suppress the effect of time-varying network delay and parameter identification error, while adding a designed polynomial compensation module to reduce tracking error and improve system responsiveness. Then, the simulation experiment verifies the system performance in comparison with different algorithms, network delay, and packet loss rate. Finally, the improved control system conducted PCI on an experimental pig, which reduced the delivery integral absolute error (IAE) by at least 20% compared with traditional methods.

Background: In recent years, recombined human growth hormone (rhGH) has been increasingly used in patients to help them recover from operation. But GH, as a mitogen, can promote cell renewal and increase malignant transformation. In the current study, we assessed the proliferation of a bile duct cancer cell line (QBC939) in vitro with GH and explored the possible relationship with the axis of GH-IGFs (insulin-like growth factors)., Methods: QBC939 cells in the exponential growth stage were harvested and divided into an experimental group (GH group) and a control group (NS group). The GH group was divided into four sub-groups according to the dose of GH and culture time (50 microg/L for 2 hours, 50 microg/L for 24 hours, 100 microg/L for 2 hours, 100 microg/L for 24 hours). The NS group was divided into two sub-groups (NS for 2 hours and NS for 24 hours). After 2 or 24 hours, IGF-1 and IGF-2 were detected using the enzyme-linked immunosorbent assay. The QBC939 cells cultured for 24 hours with two GH concentrations were made into single cell suspensions and samples underwent subsequent cell cycle evaluation. Messenger RNA of IGF-1 and IGF-2 receptor (IGF-1RmRNA and IGF-2RmRNA) were tested with the method of in situ hybridization., Results: There was no statistically significant difference between the GH and NS groups after 2 hours of culture (P>0.05). But after 24 hours of culture, GH stimulated cell growth in vitro and also elevated the percentage in S phase and the proliferation index (P<0.05). IGF-1RmRNA and IGF-2RmRNA were expressed in QBC939 in contrast to the blank group. The expression of IGF-1RmRNA increased with the dose of GH, but IGF-2RmRNA did not., Conclusion: GH can stimulate QBC939 cell growth and proliferation in vitro and the mechanism is most likely by the GH-IGF-1-IGF-1R axis.

Objective: To explore the feasibility, effect, and clinic value of total laparoscopic gastric resection in patients with benign gastric disease., Methods: The clinical materials of 50 cases underwent total laparoscopic gastric resection (LG group) and 104 cases open surgery (OG group) between January 2002 and June 2006 were compared. The operation time, intraoperative blood loss, mean time of stay in hospital and postoperative complications were studied., Results: All operations in LG group were successfully preformed with laparoscopic technique, and the mean operation time was 105 min, mean intraoperative blood loss was 50 ml, and mean hospital stay was 7 days. Incisional wound infection occurred in 2 cases and no serious complications occurred in this group. In OG group, the mean operation time was 118 min, mean intraoperative blood loss was 108 ml, and mean hospital stay was 12 days. Wound infection occurred in 7 cases, disorder of gastric emptying was found in 3 cases, fistula of anastomotic stoma happened in 1 case and bowel obstruction occurred in 1 case. There was significant difference in operation blood loss and hospital stay between the two groups (P < 0.05)., Conclusions: Laparoscopic gastric resection is a safe and feasible minimally-invasive surgery, it brings less pain, less bleeding, shorter hospital stay.

AIM:To investigate the expression of multiple genes and the behavior of cellular biology in gastric cancer (GC) and other gastric mucosal lesions and their relations to Helicobacter pylori (H. pylori) infection, tumor staging and histological subtypes.METHODS:Three hundred and twenty seven specimens of gastric mucosa obtained via endoscopy or surgical resection, and ABC immunohistochemical staining were used to detect the expression of p53, p16, Bcl-2 and COX-2 proteins.H. pylori was determined by rapid urea test combined with patholo-gical staining or 14 Curea breath test. Cellular image analysis was performed in 66 patients with intestinal metaplasia (IM) and/or dysplasia (Dys). In 30 of them, both cancer and the paracancerous tissues were obtained at the time of surgery. Histolo-gical pattern, tumor staging, lymph node metastasis, grading of differentiation and other clinical data were studied in the medical records.RESULTS:p16 expression of IM or Dys was significantly lower in positive H. pylori chronic atrophic gastritis (CAG) than those with negative H. pylori (CAG: 54.8% vs 88.0%, IM:34.4% vs 69.6%, Dys: 23.8% vs 53.6%, all P < 0.05), Bcl-2 or COX-2 expression of IM or Dys in positive H. pylori cases was signi-ficantly higher than that without H. pylori (Bcl-2: 68.8% vs 23.9%, 90.5% vs 60.7%; COX-2: 50.0% vs 10.8%, 61.8% vs 17.8%; all P <0.05). The mean number of most parame-ters of cellular image analysis in positive H. pylori group was significantly higher than that in negative H. pylori group (Ellipser: 53 plus minus 14, 40 plus minus 12&mgr;m, Area(1): 748 plus minus 572, 302 plus minus 202&mgr;m(2), Area(2): 3050 plus minus 1661, 1681 plus minus 1990&mgr;m(2), all P< 0.05; Ellipseb: 79 plus minus 23, 58 plus minus 15&mgr;m, Ratio-1: 22% plus minus5%,13% plus minus4%,Ratio-2:79% plus minus17%,53% plus minus20%,all P<0.01). There was significant correl-ation between Bcl-2 and histologic pattern of gastric carcinoma, and between COX-2 and tumor staging or lymph node metasta sis (Bcl-2: 75.0% vs16.7%; COX-2: 76.0% vs 20.0%, 79.2% vs 16.7%; all P< 0.05).CONCLUSION:p16, Bcl-2, and COX-2 but not p53 gene may play a role in the early genesis/progression of gastric carcinoma and are associated with H. pylori infection. p53 gene is relatively late event in gastric tumorigenesis and mainly relates to its progression. There is more cellular-biological behavior of malignant tumor in gastric mucosal lesions with H. pylori infec-tion. Aberrant Bcl-2 protein expression appears to be preferentially associated with the intestinal type cancer. COX-2 seems to be related to tumor staging and lymph node metastasis.