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Your search keyword '"Zhao, Yueying"' showing total 135 results
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135 results on '"Zhao, Yueying"'

17. Vitamin D3 supplementation shapes the composition of gut microbiota and improves some obesity parameters induced by high-fat diet in mice.

Author

Xiang, Lian, Du, Tingwan, Zhang, Jingjing, Zhang, Yuanfan, Zhou, Yanqiu, Zhao, Yueying, Zhou, Yong, and Ma, Ling

Subjects
RNA analysis, PREVENTION of obesity, DIETARY fiber, OBESITY, INTERLEUKINS, BODY weight, GUT microbiome, ANIMAL experimentation, CHOLECALCIFEROL, DIET, TREATMENT effectiveness, DIETARY supplements, RATS, DESCRIPTIVE statistics, TUMOR necrosis factors, RESEARCH funding, LIPIDS, BACTERIA
Abstract

Purpose: Individuals with vitamin D (VD) insufficiency have a greater tendency to develop obesity and have increased systemic inflammation. Gut microbiota are involved in the regulation of host inflammation and energy metabolism, which plays a role in the pathogenesis of obesity. Thus, we aimed to evaluate the effects of different doses of VD3 on body weight, serum lipids, inflammatory factors, and intestinal barrier function in obese mice and to explore the regulatory effect of VD3 on gut microbiota in obese mice. Methods: Male C57BL/6 J mice received a normal chow diet (NCD, 10% fat) or high-fat diet (HFD, 60% fat) to induce obesity within 10 weeks. Then, HFD mice were supplemented with 5650, 8475, or 11,300 IU VD3/kg diet for 8 weeks. Finally, 16 s rRNA analysis was performed to analyze gut microbiota composition in cecal contents. In addition, body weight, serum lipids, inflammatory factors, and intestinal barrier function were analyzed. Results: VD3 supplementation reduced body weight and the levels of TG, TC, HDL-C, TNF-α, IL-1β and LPS, and increased ZO-1 in HFD-fed mice. Moreover, it increased α-diversity, reduced F/B ratio and altered microbiota composition by increasing relative abundance of Bacteroidetes, Proteobacteria, Desulfovibrio, Dehalobacterium, Odoribacter, and Parabacteroides and reducing relative abundance of Firmicutes and Ruminococcus. There were significant differences between HFD and NCD groups in several metabolic pathways, including endotoxin biosynthesis, tricarboxylic acid cycle, lipid synthesis and metabolism, and glycolysis. Conclusions: Low, medium, and high doses of VD3 inhibited weight gain, reduced levels of blood lipids and inflammatory factors, and improved endotoxemia and gut barrier function in obese mice. It also increased the α-diversity of gut microbiota in obese mice and reduced the relative abundance of some intestinal pathogenic bacteria, increased the relative abundance of some beneficial bacteria, and corrected the intestinal flora disorder of obese mice, with the low- and high-dose groups showing better effects than the medium-dose group. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Synthesis and Application of Hybrid Aluminum Dialkylphosphinates as Highly Efficient Flame Retardants for Polyamides.

Author

Yao, Qiang, Cao, Weihong, Zhao, Yueying, and Tang, Tianbo

Subjects
FIREPROOFING agents, ALUMINUM, POLYAMIDES, X-ray diffraction, THERMAL stability, VAPORIZATION
Abstract

Hybrid aluminum dialkylphosphinates were synthesized from mixed diethyl-, ethylisobutyl-, and diisobutylphosphinates and Al3+ in water. The XRD, DSC, and TGA results of these Al phosphinates established that phosphinate ligands are randomly distributed in the species. The thermal and thermoxidative stabilities of the hybrid phosphinates were easily adjustable by varying the ratio of phosphinate ligands, a desirable feature for efficient flame retardants. The hybrid aluminum dialkylphosphinates with a relatively low ratio of diethylphosphinate demonstrated higher efficiency than Al diethylphosphinate and Al diisobutylphosphinate in flame-retarding polyamide 66. Detailed investigations on the thermal and thermoxidative stabilities of Al dialkylphosphinates and the morphologies of char obtained in UL-94 tests revealed that timely vaporization of degradation products of hybrid dialkylphosphinates at a temperature which closely matches the degradation temperature of polyamides and their ability to promote char formation of polyamides are two key factors which contribute to the excellent performance of hybrid aluminum dialkylphosphinates. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Network Pharmacology-Based Prediction and Verification of the Active Ingredients and Potential Targets of Huagan Decoction for Reflux Esophagitis

Author

Zhao, Yueying, primary, Cao, Yanfeng, additional, Yang, Xueying, additional, Guo, Mingxue, additional, Wang, Changhai, additional, Zhang, Zekang, additional, Zhang, Qing, additional, Huang, Xingyue, additional, Sun, Meng, additional, Xi, Cheng, additional, Tangthianchaichana, Jakkree, additional, Bai, Jie, additional, Du, Shouying, additional, and Lu, Yang, additional

Published
2022
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