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Your search keyword '"Zheng, Nanxin"' showing total 29 results
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29 results on '"Zheng, Nanxin"'

12. Changing trends, clinicopathological characteristics, surgical treatment patterns, and prognosis of schistosomiasis-associated versus non-schistosomiasis-associated colorectal cancer: a large retrospective cohort study of 31 153 cases in Shanghai, China (2001–2021)

Author

Zheng, Nanxin, primary, Wang, Hao, additional, Yu, Qing, additional, Wang, Chen, additional, Bai, Chen Guang, additional, Pan, An Fu, additional, Jiang, Jianjun, additional, Lu, Jian, additional, Dai, Si Min, additional, Mei, Zubing, additional, Zhang, Wei, additional, and Gao, Xian Hua, additional

Published
2023
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14. Colistin sulfate for decontamination of preservation fluid in kidney transplantation to decrease the incidence of donor‐derived infections caused by multidrug‐resistant Gram‐negative bacteria

Author

Sui, Mingxing, primary, Zheng, Nanxin, additional, Xu, Da, additional, Li, Yuhong, additional, Li, Yanhua, additional, Pu, Shijun, additional, Ji, Meili, additional, Yang, Suxia, additional, Chen, Yutong, additional, Huang, Juan, additional, Zhu, Youhua, additional, Lu, Hanlan, additional, and Zeng, Li, additional

Published
2022
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21. Application of biopolysaccharide green foam fluid to enhance CO2sequestration in high-temperature and high-salinity saline aquifer

Author

Wen, Yiping, Zheng, Nanxin, Xu, Liang, Gao, Wenbin, Hou, Yunlu, Ouyang, Tao, Li, Qi, and Zeng, Peihua

Abstract

Saline aquifer, a geological body, is widely distributed in the world and has high CO2sequestration potential. Due to the large differences in viscosity and density between the CO2and brine and the micro-heterogeneity of the saline aquifer, CO2override, and viscous fingering may occur in strata, resulting in low CO2sequestration efficiency. Following the concept of green chemistry, this study formulated CO2foam using biopolysaccharides and a green surfactant alkyl polyglycosides (APG), to enhance the CO2sequestration efficiency in saline aquifers. The ability of three biopolysaccharides (diutan gum, welan gum and xanthan gum) to stabilize CO2foam was explored. According to the foam drainage activation energy and the Ostwaldripening rate, the CO2foam with diutan gum as the stabilizer and APG as the foaming agent exhibited the favorable performance. The mechanism of diutan gum stabilizing CO2foam was analyzed through studies on intermolecular interactions, interfacial properties, rheology, and micromorphology studies. We then investigated the effects of foam quality and flow rate on the CO2foam rheology in sandstone cores by analyzing the changes in CO2saturation, the matching relationship between bubble diameters under different conditions and sandstone core pore size, and the variation in foam rheology was explained. Furthermore, the ability of CO2foam to enhance CO2sequestration was explored in saline aquifers using core-nuclear magnetic resonance techniques. CO2foam largely reduces the water saturation of macropores and establishes high-seepage resistance to facilitate CO2foam diversion to the meso- and micropores. This fully leverages the space in these pores to store CO2and greatly improves CO2sequestration in saline aquifers.

Published
2024
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25. DNA methylation profiling from circulating tumor DNA for early-detection of colorectal cancer.

Author

Zhang, Wei, primary, Sui, Jinke, additional, Wu, Xianrui, additional, Cao, Fuao, additional, Yu, Guanyu, additional, Wang, Chenyang, additional, Zhang, Zhihong, additional, Li, Bingsi, additional, Fang, Shuai, additional, Han-Zhang, Han, additional, Lou, Zheng, additional, Gong, Haifeng, additional, Liu, Lianjie, additional, Zheng, Nanxin, additional, Hao, Liqiang, additional, and Lan, Ping, additional

Published
2019
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29. Alsterpaullone induces apoptosis of HepG2 cells via a p38 mitogen-activated protein kinase signaling pathway.

Author

Yin, Peng, Zheng, Nanxin, Dong, Junfeng, Xu, Chunyang, Zhang, Xiaomei, and Ding, Guoshan

Subjects
*MITOGEN-activated protein kinases, *CYCLIN-dependent kinases, *CELL tumors
Abstract

Alsterpaullone (Alp) is a small-molecule inhibitor that targets cyclin-dependent kinases to inhibit tumor cell activity. However, to the best of our knowledge, the effect of Alp on hepatoblastoma has not been investigated. Therefore, the function of Alp in apoptotic induction of hepatoblastoma cells and a potential mechanism of action were investigated. Results indicated that low doses of Alp (1 µM) significantly induced apoptosis in the HepG2 hepatoblastoma cell line. In vivo experiments of tumor suppression further indicated that Alp (3 mg/kg) exerted an inhibitory effect on HepG2 ×enograft tumor growth. Following Alp treatment, the expression level of B-cell lymphoma 2 (Bcl-2)-associated X protein, and cleaved caspase-3 and −9 in HepG2 cells was significantly increased; however, the expression of Bcl-2 was significantly decreased. In addition, phosphorylation of p38 mitogen-activated protein kinase (MAPK) significantly decreased Alp-induced caspase-3 and −9 activation. These results suggested that Alp induces apoptosis and inhibited proliferation via the p38MAPK signaling pathway. Therefore, Alp may be a therapeutic agent for treating hepatoblastoma. [ABSTRACT FROM AUTHOR]

Published
2019

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