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Visible-infrared person re-identification (VI-ReID) task aims to retrieve the same person between visible and infrared images. VI-ReID is challenging as the images captured by different spectra present large cross-modality discrepancy. Many methods adopt a two-stream network and design additional constraint conditions to extract shared features for different modalities. However, the interaction between the feature extraction processes of different modalities is rarely considered. In this paper, a partially interactive collaboration method is proposed to exploit the complementary information of different modalities to reduce the modality gap for VI-ReID. Specifically, the proposed method is achieved in a partially interactive-shared architecture: collaborative shallow layers and shared deep layers. The collaborative shallow layers consider the interaction between modality-specific features of different modalities, encouraging the feature extraction processes of different modalities constrain each other to enhance feature representations. The shared deep layers further embed the modality-specific features to a common space to endow them the same identity discriminability. To ensure the interactive collaborative learning implement effectively, the conventional loss and collaborative loss are utilized jointly to train the whole network. Extensive experiments on two publicly available VI-ReID datasets verify the superiority of the proposed PIC method. Specifically, the proposed method achieves a rank-1 accuracy of 83.6% and 57.5% on RegDB and SYSU-MM01 datasets, respectively. [ABSTRACT FROM AUTHOR]

Hyperspectral image (HSI) classification refers to identifying land-cover categories of pixels based on spectral signatures and spatial information of HSIs. In recent deep learning-based methods, to explore the spatial information of HSIs, the HSI patch is usually cropped from original HSI as the input. And $3 \times 3$ convolution is utilized as a key component to capture spatial features for HSI classification. However, the $3 \times 3$ convolution is sensitive to the spatial rotation of inputs, which results in that recent methods perform worse in rotated HSIs. To alleviate this problem, a rotation-invariant attention network (RIAN) is proposed for HSI classification. First, a center spectral attention (CSpeA) module is designed to avoid the influence of other categories of pixels to suppress redundant spectral bands. Then, a rectified spatial attention (RSpaA) module is proposed to replace $3 \times 3$ convolution for extracting rotation-invariant spectral-spatial features from HSI patches. The CSpeA module, the $1 \times 1$ convolution and the RSpaA module are utilized to build the proposed RIAN for HSI classification. Experimental results demonstrate that RIAN is invariant to the spatial rotation of HSIs and has superior performance, e.g., achieving an overall accuracy of 86.53% (1.04% improvement) on the Houston database. The codes of this work are available at https://github.com/spectralpublic/RIAN. [ABSTRACT FROM AUTHOR]

Ship detection is an important research topic in the field of remote sensing. Compared with optical detection methods, Synthetic Aperture Radar (SAR) ship detection can penetrate clouds to detect hidden ships in all-day and all-weather. Currently, the state-of-the-art methods exploit convolutional neural networks to train ship detectors, which require a considerable labeled dataset. However, it is difficult to label the SAR images because of expensive labor and well-trained experts. To address the above limitations, this paper explores a cross-domain ship detection task, which adapts the detector from labeled optical images to unlabeled SAR images. There is a significant visual difference between SAR images and optical images. To achieve cross-domain detection, the multi-level alignment network, which includes image-level, convolution-level, and instance-level, is proposed to reduce the large domain shift. First, image-level alignment exploits generative adversarial networks to generate SAR images from the optical images. Then, the generated SAR images and the real SAR images are used to train the detector. To further minimize domain distribution shift, the detector integrates convolution-level alignment and instance-level alignment. Convolution-level alignment trains the domain classifier on each activation of the convolutional features, which minimizes the domain distance to learn domain-invariant features. Instance-level alignment reduces domain distribution shift on the features extracted from the region proposals. The entire multi-level alignment network is trained end-to-end and its effectiveness is proved on multiple cross-domain ship detection datasets. [ABSTRACT FROM AUTHOR]

Human action can be recognized in still images since the whole image represents an action with some spatial clues, such as human poses, action-specific parts, and global surroundings. To represent the spatial clues, the recent methods require labor-intensive annotations to locate the human body and objects, which are computationally intensive. To eliminate strong supervision, a Multiple Spatial Clues Network (MSCNet) is proposed to represent the spatial clues with only image-level action label. Neither accurately manual annotated bounding boxes nor extra labeled datasets are required as additional supervision. First, the proposed MSCNet exploits spatial-attention module to generate spatial attention regions, and detects the spatial clues with minimal supervision. Then, spatial clues exploitation is proposed to utilize the learned spatial clues with three modules: the context module, body + context module and body + semantics module. Experiments on three benchmark datasets demonstrate the effectiveness of the proposed MSCNet. [ABSTRACT FROM AUTHOR]

Remote sensing images (RSIs) containing various ground objects have been applied in many fields. To make semantic understanding of RSIs objective and interactive, the task remote sensing visual question answering (VQA) has appeared. Given an RSI, the goal of remote sensing VQA is to make an intelligent agent answer a question about the remote sensing scene. Existing remote sensing VQA methods utilized a nonspatial fusion strategy to fuse the image features and question features, which ignores the spatial information of images and word-level information of questions. A novel method is proposed to complete the task considering these two aspects. First, convolutional features of the image are included to represent spatial information, and the word vectors of questions are adopted to present semantic word information. Second, attention mechanism and bilinear technique are introduced to enhance the feature considering the alignments between spatial positions and words. Finally, a fully connected layer with softmax is utilized to output an answer from the perspective of the multiclass classification task. To benchmark this task, a RSIVQA dataset is introduced in this article. For each of more than 37 000 RSIs, the proposed dataset contains at least one or more questions, plus corresponding answers. Experimental results demonstrate that the proposed method can capture the alignments between images and questions. The code and dataset are available at https://github.com/spectralpublic/RSIVQA. [ABSTRACT FROM AUTHOR]

Change detection (CD) aims to identify the differences between multitemporal images acquired over the same geographical area at different times. With the advantages of requiring no cumbersome labeled change information, unsupervised CD has attracted extensive attention of researchers. Multitemporal images tend to have different resolutions as they are usually captured at different times with different sensor properties. It is difficult to directly obtain one pixelwise change map for two images with different resolutions, so current methods usually resize multitemporal images to a unified size. However, resizing operations change the original information of pixels, which limits the final CD performance. This article aims to detect changes from multitemporal images in the originally different resolutions without resizing operations. To achieve this, a cross-resolution difference learning method is proposed. Specifically, two cross-resolution pixelwise difference maps are generated for the two different resolution images and fused to produce the final change map. First, the two input images are segmented into individual homogeneous regions separately due to different resolutions. Second, each pixelwise difference map is produced according to two measure distances, the mutual information distance and the deep feature distance, between image regions in which the pixel lies. Third, the final binary change map is generated by fusing and binarizing the two cross-resolution difference maps. Extensive experiments on four datasets demonstrate the effectiveness of the proposed method for detecting changes from different resolution images. [ABSTRACT FROM AUTHOR]

The land cover classification has been an important task in remote sensing. With the development of various sensors technologies, carrying out classification work with multisource remote sensing (MSRS) data has shown an advantage over using a single type of data. Hyperspectral images (HSIs) are able to represent the spectral properties of land cover, which is quite common for land cover understanding. Light detection and ranging (LiDAR) images contain altitude information of the ground, which is greatly helpful with urban scene analysis. Current HSI and LiDAR fusion methods perform feature extraction and feature fusion separately, which cannot well exploit the correlation of data sources. In order to make full use of the correlation of multisource data, an unsupervised feature extraction-fusion network for HSI and LiDAR, which utilizes feature fusion to guide the feature extraction procedure, is proposed in this article. More specifically, the network takes multisource data as input and directly output the unified fused feature. A multimodal graph is constructed for feature fusion, and graph-based loss functions including Laplacian loss and t-distributed stochastic neighbor embedding (t-SNE) loss are utilized to constrain the feature extraction network. Experimental results on several data sets demonstrate the proposed network can achieve more excellent classification performance than some state-of-the-art methods. [ABSTRACT FROM AUTHOR]

Cross-domain scene classification identifies scene categories by learning knowledge from a labeled data set (source domain) to an unlabeled data set (target domain), where the source data and the target data are sampled from different distributions. A lot of domain adaptation methods are used to reduce the distribution shift across domains, and most existing methods assume that the source domain shares the same categories with the target domain. It is usually hard to find a source domain that covers all categories in the target domain. Some works exploit multiple incomplete source domains to cover the target domain. However, in such setting, the categories of each source domain are a subset of the target-domain categories, and the target domain contains “unknown” categories for each source domain. The existence of unknown categories results in the conventional domain adaptation unsuitable. Known and unknown categories should be treated separately. Therefore, a separation mechanism is proposed to separate the known and unknown categories in this article. First, multiple-source classifiers trained on the multiple source domains are used to coarsely separate the known/unknown categories in the target domain. The target images with high similarities to source images are selected as known categories, and the target images with low similarities are selected as unknown categories. Then, a binary classifier trained using the selected images is used to finely separate all target-domain images. Finally, only the known categories are implemented in the cross-domain alignment and classification. The target images get labels by integrating the hypotheses of multiple-source classifiers on the known categories. Experiments are conducted on three cross-domain data sets to demonstrate the effectiveness of the proposed method. [ABSTRACT FROM AUTHOR]

Person re-identification (ReID) task aims to retrieve the same person across multiple spatially disjoint camera views. Due to huge image changes caused by various factors such as posture variation and illumination transformation, images of different persons may share the more similar appearances than images of the same one. Learning discriminative representations to distinguish details of different persons is significant for person ReID. Many existing methods learn discriminative representations resorting to a human body part location branch which requires cumbersome expert human annotations or complex network designs. In this article, a novel bidirectional interaction network is proposed to explore discriminative representations for person ReID without any human body part detection. The proposed method regards multiple convolutional features as responses to various body part properties and exploits the inter-layer interaction to mine discriminative representations for person identities. Firstly, an inter-layer bilinear pooling strategy is proposed to feasibly exploit the pairwise feature relations between two convolution layers. Secondly, to explore interaction of multiple layers, an effective bidirectional integration strategy consisting of two different multi-layer interaction processes is designed to aggregate bilinear pooling interaction of multiple convolution layers. The interaction of multiple layers is implemented in a layer-by-layer nesting policy to ensure the two interaction processes are different and complementary. Extensive experiments validate the superiority of the proposed method on four popular person ReID datasets including Market-1501, DukeMTMC-ReID, CUHK03-NP and MSMT17. Specifically, the proposed method achieves a rank-1 accuracy of 95.1% and 88.2% on Market-1501 and DukeMTMC-ReID, respectively. [ABSTRACT FROM AUTHOR]

Audio is the main form for the visually impaired to obtain information. In reality, all kinds of visual data always exist, but audio data does not exist in many cases. In order to help the visually impaired people to better perceive the information around them, an image-to-audio-description (I2AD) task is proposed to generate audio descriptions from images in this paper. To complete this totally new task, a modal translation network (MT-Net) from visual to auditory sense is proposed. The proposed MT-Net includes three progressive sub-networks: 1) feature learning, 2) cross-modal mapping, and 3) audio generation. First, the feature learning sub-network aims to learn semantic features from image and audio, including image feature learning and audio feature learning. Second, the cross-modal mapping sub-network transforms the image feature into a cross-modal representation with the same semantic concept as the audio feature. In this way, the correlation of inter-modal data is effectively mined for easing the heterogeneous gap between image and audio. Finally, the audio generation sub-network is designed to generate the audio waveform from the cross-modal representation. The generated audio waveform is interpolated to obtain the corresponding audio file according to the sample frequency. Being the first attempt to explore the I2AD task, three large-scale datasets with plenty of manual audio descriptions are built. Experiments on the datasets verify the feasibility of generating intelligible audio from an image directly and the effectiveness of proposed method. [ABSTRACT FROM AUTHOR]

Remote sensing image (RSI) classification is one of the most important fields in RSI processing. It is well known that RSIs are very complicated due to its various kinds of contents. Therefore, it is very difficult to distinguish different scene categories with similar visual contents, like desert and bare land. To address hard negative categories, an attribute-cooperated convolutional neural network (ACCNN) is proposed to exploit attributes as additional guiding information. First, the classification branch extracts convolutional neural network feature, which is then utilized to recognize the RSI scene categories. Second, the attribute branch is proposed to make the network distinguish scene categories efficiently. The proposed attribute branch shares feature extraction layers with the classification branch and makes the classification branch aware of extra attribute information. Finally, the relationship branch constraints the relationship between the classification branch and the attribute branch. To exploit the attribute information, three attribute-classification data sets are generated (AC-AID, AC-UCM, and AC-Sydney). Experimental results show that the proposed method is competitive to state-of-the-art methods. The data sets are available at https://github.com/CrazyStoneonRoad/Attribute-Cooperated-Classification-Data sets. [ABSTRACT FROM AUTHOR]

Visual semantic parts play crucial roles in still image-based action recognition. A majority of existing methods require additional manual annotations such as human bounding boxes and predefined body parts besides action labels to learn action related visual semantic parts. However, labeling these manual annotations is rather time-consuming and labor-intensive. Moreover, not all manual annotations are effective when recognizing a specific action. Some of them can be irrelevant and even misguided. To address these limitations, this paper proposes a multi-stage deep learning method called Spatial Attention based Action Mask Networks (SAAM-Nets). The proposed method does not need any additional annotations besides action labels to obtain action-specific visual semantic parts. Instead, we propose a spatial attention layer injected in a convolutional neural network to create a specific action mask for each image with only action labels. Moreover, based on the action mask, we propose a region selection strategy to generate a semantic bounding box containing action-specific semantic parts. Furthermore, to effectively combine the information of the whole scene and the sematic box, two feature attention layers are adopted to obtain more discriminative representations. Experiments on four benchmark datasets have demonstrated that the proposed method can achieve promising performance compared with state-of-the-art methods. [ABSTRACT FROM AUTHOR]

Hashing has been widely used for large-scale multimedia retrieval because of its advantages in storage and retrieval efficiency. Traditional supervised hash methods represent an image as a feature vector and then perform a separate quantization step to generate a binary code. Due to the difficulty of discrete optimization of hash codes, continuous relaxation is generally used to replace discrete optimization. However, the process of continuous relaxation leads to inevitable quantization error. To avoid this drawback, a deep balanced discrete hashing method is proposed, which uses discrete gradient propagation with the straight-through estimator. The proposed method does not use the traditional continuous relaxation strategy, thereby reducing the quantization error caused by continuous relaxation. And the proposed method uses supervised information to directly guide the discrete coding and deep feature learning process. In the proposed method, the last layer of the Convolutional Neural Network (CNN) outputs the binary code directly. In the loss function, discrete values are calculated by combining the pairwise loss and a balance controlling term. The learned binary hash code maintains the similar relationship and label consistency at the same time. While maintaining the pairwise similarity, the proposed method keeps the balance of hash codes to improve retrieval performance. Extensive experiments show that the proposed method outperforms the state-of-the-art hashing methods on four image retrieval benchmark datasets. [ABSTRACT FROM AUTHOR]

This paper studies the task of 3D human pose estimation from a single RGB image, which is challenging without depth information. Recently many deep learning methods are proposed and achieve great improvements due to their strong representation learning. However, most existing methods ignore the relationship between joint features. In this paper, a joint relationship aware neural network is proposed to take both global and local joint relationship into consideration. First, a whole feature block representing all human body joints is extracted by a convolutional neural network. A Dual Attention Module (DAM) is applied on the whole feature block to generate attention weights. By exploiting the attention module, the global relationship between the whole joints is encoded. Second, the weighted whole feature block is divided into some individual joint features. To capture salient joint feature, the individual joint features are refined by individual DAMs. Finally, a joint angle prediction constraint is proposed to consider local joint relationship. Quantitative and qualitative experiments on 3D human pose estimation benchmarks demonstrate the effectiveness of the proposed method. [ABSTRACT FROM AUTHOR]

Hyperspectral image (HSI) classification aims to assign each hyperspectral pixel with a proper land-cover label. Recently, convolutional neural networks (CNNs) have shown superior performance. To identify the land-cover label, CNN-based methods exploit the adjacent pixels as an input HSI cube, which simultaneously contains spectral signatures and spatial information. However, at the edge of each land-cover area, an HSI cube often contains several pixels whose land-cover labels are different from that of the center pixel. These pixels, named interfering pixels, will weaken the discrimination of spectral–spatial features and reduce classification accuracy. In this article, a spectral–spatial attention network (SSAN) is proposed to capture discriminative spectral–spatial features from attention areas of HSI cubes. First, a simple spectral–spatial network (SSN) is built to extract spectral–spatial features from HSI cubes. The SSN is composed of a spectral module and a spatial module. Each module consists of only a few 3-D convolution and activation operations, which make the proposed method easy to converge with a small number of training samples. Second, an attention module is introduced to suppress the effects of interfering pixels. The attention module is embedded into the SSN to obtain the SSAN. The experiments on several public HSI databases demonstrate that the proposed SSAN outperforms several state-of-the-art methods. [ABSTRACT FROM AUTHOR]

Hyperspectral images (HSIs) convey more useful information than RGB or gray images, which are widely used in many remote sensing tasks. In real scenarios, HSIs are inevitably corrupted by noise because of sensors’ imperfectness or atmospheric influence. Recently, many HSI denoising methods have been proposed to utilize the interband information between different spectral bands. However, these methods regard the HSI as a whole and treat the different spectral bands with the same noise level. In fact, the noise levels in different bands are different. Especially, only few certain bands are corrupted by noise, named the target noised bands. Under this circumstance, an HSI denoising method is proposed by considering the band relationship and different noise levels. The target noised bands are adaptively denoised by fusing some selected bands. Specifically, some related but quality superior bands are selected according to the target noised bands. Then, the target noised bands can be denoised by fusing the selected related bands. Experimental results show that the proposed method achieves considerable performances in comparison with several state-of-the-art hyperspectral denoising methods. [ABSTRACT FROM AUTHOR]

Dimensionality reduction (DR) has attracted extensive attention since it provides discriminative information of hyperspectral images (HSI) and reduces the computational burden. Though DR has gained rapid development in recent years, it is difficult to achieve higher classification accuracy while preserving the relevant original information of the spectral bands. To relieve this limitation, in this paper, a different DR framework is proposed to perform feature extraction on the selected bands. The proposed method uses determinantal point process to select the representative bands and to preserve the relevant original information of the spectral bands. The performance of classification is further improved by performing multiple Laplacian eigenmaps (LEs) on the selected bands. Different from the traditional LEs, multiple Laplacian matrices in this paper are defined by encoding spatial–spectral proximity on each band. A common low-dimensional representation is generated to capture the joint manifold structure from multiple Laplacian matrices. Experimental results on three real-world HSIs demonstrate that the proposed framework can lead to a significant advancement in HSI classification compared with the state-of-the-art methods. [ABSTRACT FROM PUBLISHER]

With the rapid development of the satellite sensor technology, high spatial resolution remote sensing (HSR) data have attracted extensive attention in military and civilian applications. In order to make full use of these data, remote sensing scene classification becomes an important and necessary precedent task. In this paper, an unsupervised representation learning method is proposed to investigate deconvolution networks for remote sensing scene classification. First, a shallow weighted deconvolution network is utilized to learn a set of feature maps and filters for each image by minimizing the reconstruction error between the input image and the convolution result. The learned feature maps can capture the abundant edge and texture information of high spatial resolution images, which is definitely important for remote sensing images. After that, the spatial pyramid model (SPM) is used to aggregate features at different scales to maintain the spatial layout of HSR image scene. A discriminative representation for HSR image is obtained by combining the proposed weighted deconvolution model and SPM. Finally, the representation vector is input into a support vector machine to finish classification. We apply our method on two challenging HSR image data sets: the UCMerced data set with 21 scene categories and the Sydney data set with seven land-use categories. All the experimental results achieved by the proposed method outperform most state of the arts, which demonstrates the effectiveness of the proposed method. [ABSTRACT FROM PUBLISHER]

Band selection, as a special case of the feature selection problem, tries to remove redundant bands and select a few important bands to represent the whole image cube. This has attracted much attention, since the selected bands provide discriminative information for further applications and reduce the computational burden. Though hyperspectral band selection has gained rapid development in recent years, it is still a challenging task because of the following requirements: 1) an effective model can capture the underlying relations between different high-dimensional spectral bands; 2) a fast and robust measure function can adapt to general hyperspectral tasks; and 3) an efficient search strategy can find the desired selected bands in reasonable computational time. To satisfy these requirements, a multigraph determinantal point process (MDPP) model is proposed to capture the full structure between different bands and efficiently find the optimal band subset in extensive hyperspectral applications. There are three main contributions: 1) graphical model is naturally transferred to address band selection problem by the proposed MDPP; 2) multiple graphs are designed to capture the intrinsic relationships between hyperspectral bands; and 3) mixture DPP is proposed to model the multiple dependencies in the proposed multiple graphs, and offers an efficient search strategy to select the optimal bands. To verify the superiority of the proposed method, experiments have been conducted on three hyperspectral applications, such as hyperspectral classification, anomaly detection, and target detection. The reliability of the proposed method in generic hyperspectral tasks is experimentally proved on four real-world hyperspectral data sets. [ABSTRACT FROM PUBLISHER]

Subpixel hyperspectral detection is a kind of method which tries to locate targets in a hyperspectral image when the spectrum of the targets is given. Due to its subpixel nature, targets are often smaller than one pixel, which increases the difficulty of detection. Many algorithms have been proposed to tackle this problem, most of which model the noise in all spatial points of hyperspectral image by multivariate normal distribution. However, this model alone may not be an appropriate description of the noise distribution in hyperspectral image. After carefully studying the distribution of hyperspectral image, it is concluded that the gradient of noise also obeys normal distribution. In this paper two detectors are proposed: mixture gradient structured detector (MGSD) and mixture gradient unstructured detector (MGUD). These detectors are based on a new model which takes advantage of the distribution of the gradient of the noise. This makes the detectors more accordant with the practical situation. To evaluate the performance of the proposed detectors, three different data sets, including one synthesized data set and two real-world data sets, are used in the experiments. Results show that the proposed detectors have better performance than current subpixel detectors. [ABSTRACT FROM AUTHOR]

Action recognition has been standing as an active research topic over the past years. Many efforts have been made and many methods have been proposed. However, there are still some challenges such as illumination condition, viewpoint, camera motion and cluttered background. In order to tackle these challenges, a discriminative representation is proposed by discovering key information of the input data. This task can be addressed by improvements of two major components: parameterized representation and discriminative classifier. The representation is parameterized with hidden variables and can be learned from training data. And the classifier can be trained to recognize actions based on the proposed representation. The contributions of this paper are as follows: (1) a novel probabilistic representation is utilized to capture the relative significant information of low level features; (2) a novel framework is proposed by combining the parameterized representation and discriminative classifier; (3) an alternating strategy is favorable to improve the performance of action recognition by updating the representation and the classifier alternatively. Experimental results on five well-known datasets demonstrate that the proposed method significantly improves the performance in action recognition. [ABSTRACT FROM AUTHOR]

Noise contamination is a ubiquitous problem in hyperspectral images (HSIs), which is a challenging and promising theme in many remote sensing applications. A large number of methods have been proposed to remove noise. Unfortunately, most denoising methods fail to take full advantages of the high spectral correlation and to simultaneously consider the specific noise distributions in HSIs. Recently, a spectral–spatial adaptive hyperspectral total variation (SSAHTV) was proposed and obtained promising results. However, the SSAHTV model is insensitive to the image details, which makes the edges blur. To overcome all of these drawbacks, a spectral–spatial kernel method for HSI denoising is proposed in this paper. The proposed method is inspired by the observation that the spectral–spatial information is highly redundant in HSIs, which is sufficient to estimate the clear images. In this paper, a spectral–spatial kernel regularization is proposed to maintain the spectral correlations in spectral dimension and to match the original structure between two spatial dimensions. Moreover, an adaptive mechanism is developed to balance the fidelity term according to different noise distributions in each band. Therefore, it cannot only suppress noise in the high-noise band but also preserve information in the low-noise band. The reliability of the proposed method in removing noise is experimentally proved on both simulated data and real data. [ABSTRACT FROM PUBLISHER]

Abstract: Small interfering RNAs (siRNAs) delivery remains a bottleneck for RNA interference (RNAi) – based therapies in the clinic. In the present study, a fusion protein with two cell-penetrating peptides (CPP), Hph1–Hph1, and a double-stranded RNA binding domain (dsRBD), was constructed for the siRNA delivery: dsRBD was designed to bind siRNA, and CPP would subsequently transport the dsRBD/siRNA complex into cells. We assessed the efficiency of the fusion protein, Hph1–Hph1–dsRBD, as a siRNA carrier. Calcium-condensed effects were assessed on GAPDH and green fluorescent protein (GFP) genes by western blot, real time polymerase chain reaction (RT-PCR), and flow cytometry analysis in vitro. Evaluations were also made in an in vivo heart transplantation model. The results demonstrated that the fusion protein, Hph1–Hph1–dsRBD, is highly efficient at delivering siRNA in vitro, and exhibits efficiency on GAPDH and GFP genes similar to or greater than lipofectamine. Interestingly, the calcium-condensed effects dramatically enhanced cellular uptake of the protein–siRNA complex. In vivo, Hph1–Hph1–dsRBD transferred and distributed ^ targeted siRNA throughout the whole mouse heart graft. Together, these results indicate that Hph1–Hph1–dsRBD has potential as an siRNA carrier for applications in the clinic or in biomedical research. [Copyright &y& Elsevier]

Recently, many convolutional networks have been built to fuse a low spatial resolution (LR) hyperspectral image (HSI) and a high spatial resolution (HR) multispectral image (MSI) to obtain HR HSIs. However, most deep learning-based methods are supervised methods, which require sufficient HR HSIs for supervised training. Collecting plenty of HR HSIs is laborious and time-consuming. In this paper, a self-supervised spectral-spatial residual network (SSRN) is proposed to alleviate dependence on a mass of HR HSIs. In SSRN, the fusion of HR MSIs and LR HSIs is considered a pixel-wise spectral mapping problem. Firstly, this paper assumes that the spectral mapping between HR MSIs and HR HSIs can be approximated by the spectral mapping between LR MSIs (derived from HR MSIs) and LR HSIs. Secondly, the spectral mapping between LR MSIs and LR HSIs is explored by SSRN. Finally, a self-supervised fine-tuning strategy is proposed to transfer the learned spectral mapping to generate HR HSIs. SSRN does not require HR HSIs as the supervised information in training. Simulated and real hyperspectral databases are utilized to verify the performance of SSRN. [ABSTRACT FROM AUTHOR]

Subtle facial expression recognition (SFER) aims to classify facial expressions with very low intensity into corresponding human emotions. Subtle facial expression can be regarded as a special kind of facial expression, whose facial muscle movements are more difficult to capture. In the last decade, various methods have been developed for common facial expression recognition (FER). However, most of them failed to automatically find the most discriminative parts of facial expression and the correlation of muscle movements when human makes facial expression, which makes them unsuitable for SFER. To better solve SFER problem, an attention mechanism based model focusing on salient local regions and their correlations is proposed in this paper. The proposed method: 1) utilizes multiple attention blocks to attend to distinct discriminative regions and extract corresponding local features automatically, 2) a correlation attention module is integrated in the model to extract global correlation feature over the salient regions, and finally 3) fuses the correlation feature and local features in an efficient way for the final facial expression classification. By this way, the useful but subtle local information can be utilized in more detail, and the correlation of different local regions is also extracted. Extensive experiment on the LSEMSW and CK+ datasets shows that the method proposed in this paper achieves superior results, which demonstrates its effectiveness. [ABSTRACT FROM AUTHOR]

Cross-domain scene classification refers to the scene classification task in which the training set (termed source domain) and the test set (termed target domain) come from different distributions. Various domain adaptation methods have been developed to reduce the distribution discrepancy between different domains. However, current domain adaptation methods assume that the source domain and target domain share the same categories. In reality, it is hard to find a source domain that can completely cover all the categories of target domain. In this article, we propose to use multiple complementary source domains to form the categories of target domain. A multisource compensation network (MSCN) is proposed to tackle these challenges: distribution discrepancy and category incompleteness. First, a pretrained convolutional neural network (CNN) is exploited to learn the feature representation for each domain. Second, a cross-domain alignment module is developed to reduce the domain shift between source and target domains. Domain shift is reduced by mapping the two domain features into a common feature space. Finally, a classifier complement module is proposed to align categories in multiple sources and learn a target classifier. Two cross-domain classification data sets are constructed using four heterogeneous remote sensing scene classification data sets. Extensive experiments are conducted on these datasets to validate the effectiveness of the proposed method. The proposed method can achieve 81.23% and 81.97% average accuracies on two-source-complementary data set and three-source-complementary data set, respectively. [ABSTRACT FROM AUTHOR]

Attention mechanism-based image captioning methods have achieved good results in the remote sensing field, but are driven by tagged sentences, which is called passive attention. However, different observers may give different levels of attention to the same image. The attention of observers during testing, then, may not be consistent with the attention during training. As a direct and natural human–machine interaction, speech is much faster than typing sentences. Sound can represent the attention of different observers. This is called active attention. Active attention can be more targeted to describe the image; for example, in disaster assessments, the situation can be obtained quickly and the corresponding disaster areas can be located related to the specific disaster. A novel sound active attention framework is proposed for more specific caption generation according to the interest of the observer. First, sound is modeled by mel-frequency cepstral coefficients (MFCCs) and the image is encoded by convolutional neural networks (CNNs). Then, to handle the continuity characteristic of sound, a sound module and an attention module are designed based on the gated recurrent units (GRUs). Finally, the sound-guided image feature processed by the attention module is imported into the output module to generate descriptive sentence. Experiments based on both fake and real sound data sets show that the proposed method can generate sentences that can capture the focus of human. [ABSTRACT FROM AUTHOR]

Remote sensing (RS) scene classification is a challenging task due to various land covers contained in RS scenes. Recent RS classification methods demonstrate that aggregating the multilayer convolutional features, which are extracted from different hierarchical layers of a convolutional neural network, can effectively improve classification accuracy. However, these methods treat the multilayer convolutional features as equally important and ignore the hierarchical structure of multilayer convolutional features. Multilayer convolutional features not only provide complementary information for classification but also bring some interference information (e.g., redundancy and mutual exclusion). In this paper, a gated bidirectional network is proposed to integrate the hierarchical feature aggregation and the interference information elimination into an end-to-end network. First, the performance of each convolutional feature is quantitatively analyzed and a superior combination of convolutional features is selected. Then, a bidirectional connection is proposed to hierarchically aggregate multilayer convolutional features. Both the top–down direction and the bottom–up direction are considered to aggregate multilayer convolutional features into the semantic-assist feature and appearance-assist feature, respectively, and a gated function is utilized to eliminate interference information in the bidirectional connection. Finally, the semantic-assist feature and appearance-assist feature are merged for classification. The proposed method can compete with the state-of-the-art methods on four RS scene classification data sets (AID, UC-Merced, WHU-RS19, and OPTIMAL-31). [ABSTRACT FROM AUTHOR]

Remote sensing scene classification (RSSC) refers to inferring semantic labels based on the content of the remote sensing scenes. Recently, most works take the pretrained convolutional neural network (CNN) as the feature extractor to build a scene representation for RSSC. The activations in different layers of CNN (named intermediate features) contain different spatial and semantic information. Recent works demonstrate that aggregating intermediate features into a scene representation can significantly improve the classification accuracy for RSSC. However, the intermediate features are aggregated by some unsupervised feature encoding methods (e.g., Bag-of-Visual-Words). Little attention has been paid to explore the information of semantic labels for the feature aggregation. In this paper, in order to explore the semantic label information, an end-to-end feature aggregation CNN (FACNN) is proposed to learn a scene representation for RSSC. In FACNN, a supervised convolutional features’ encoding module and a progressive aggregation strategy are proposed to leverage the semantic label information to aggregate the intermediate features. The FACNN integrates the feature learning, feature aggregation, and classifier into a unified end-to-end framework for joint training. In FACNN, the scene representation is learned by considering the information of semantic labels, which can result in better performance for RSSC. Extensive experiments on AID, UC-Merged, and WHU-RS19 databases demonstrate that FACNN performs better than several state-of-the-art methods. [ABSTRACT FROM AUTHOR]

Inspired by recent development of artificial satellite, remote sensing images have attracted extensive attention. Recently, notable progress has been made in scene classification and target detection. However, it is still not clear how to describe the remote sensing image content with accurate and concise sentences. In this paper, we investigate to describe the remote sensing images with accurate and flexible sentences. First, some annotated instructions are presented to better describe the remote sensing images considering the special characteristics of remote sensing images. Second, in order to exhaustively exploit the contents of remote sensing images, a large-scale aerial image data set is constructed for remote sensing image caption. Finally, a comprehensive review is presented on the proposed data set to fully advance the task of remote sensing caption. Extensive experiments on the proposed data set demonstrate that the content of the remote sensing image can be completely described by generating language descriptions. The data set is available at https://github.com/201528014227051/RSICD_optimal. [ABSTRACT FROM AUTHOR]

Mesenchymal stem cells derived extracellular vesicles improve LPS-induced liver injury by inhibiting HIF-1α dependent glycolysis pathway in Kupffer cells, promoting the transformation of Kupffer cells into M2 phenotype. [Display omitted] • MSC-EVs inhibits inflammation and attenuated LPS-induced liver injury. • MSC-EVs promote the conversion of macrophages from M1 to M2 in SALD model. • MSC-EVs regulate macrophage function by inhibiting glycolytic pathway. • MSC-EVs regulate the glycolytic pathway by regulating HIF-1α. Sepsis-associated liver dysfunction (SALD) aggravates the disease progression and prognosis of patients. Macrophages in the liver play a crucial role in the occurrence and development of SALD. Human umbilical cord mesenchymal stem cells (MSCs), by secreting extracellular vesicles (EVs), show beneficial effects in various inflammatory diseases. However, whether MSC-derived EVs (MSC-EVs) could ameliorate the inflammatory response in liver macrophages and the underlying mechanisms remain unclear. In this study, a mouse model of sepsis induced by lipopolysaccharide (LPS) challenge was used to investigate the immunomodulatory functions of MSC-EVs in SALD. LPS-stimulated primary Kupffer cells (KCs) and Raw264.7 were used to further explore the potential mechanisms of MSC-EVs in regulating the inflammatory response of macrophages. The results showed that MSC-EVs alleviated liver tissue injury and facilitated the polarization of M1 to M2 macrophages. Further in vitro studies confirmed that MSC-EVs treatment significantly downregulated the expression of several enzymes related to glycolysis and reduced the glycolytic flux by inhibiting hypoxia-inducible factor 1α (HIF-1α) expression, thus effectively inhibiting the inflammatory responses of macrophages. These findings reveal that the application of MSC-EVs might be a potential therapeutic strategy for treating SALD. [ABSTRACT FROM AUTHOR]

Abstract Scene classification has become an effective way to interpret the High Spatial Resolution (HSR) remote sensing images. Recently, Convolutional Neural Networks (CNN) have been found to be excellent for scene classification. However, only using the deep models as feature extractor on the aerial image directly is not proper, because the extracted deep features can not capture spatial scale variability and rotation variability in HSR remote sensing images. To relieve this limitation, a bidirectional adaptive feature fusion strategy is investigated to deal with the remote sensing scene classification. The deep learning feature and the SIFT feature are fused together to get a discriminative image presentation. The fused feature can not only describe the scenes effectively by employing deep learning feature but also overcome the scale and rotation variability with the usage of the SIFT feature. By fusing both SIFT feature and global CNN feature, our method achieves state-of-the-art scene classification performances on the UCMerced, the Sydney and the AID datasets. [ABSTRACT FROM AUTHOR]