1. Recurrence of odontogenic keratocysts and possible prognostic factors : review of 455 patients
- Author
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Bing Liu, Zheng Yueyu, Yanfang Sun, Wu Tianfu, Nyimi-Bushabu Fidele, Yi-Fang Zhao, and Jin-Yuan Liu
- Subjects
Adult ,Male ,medicine.medical_specialty ,Subsequent Relapse ,Enucleation ,Perforation (oil well) ,Odontogenic Tumors ,Lesion ,03 medical and health sciences ,0302 clinical medicine ,Recurrence ,Epidemiology ,Humans ,Medicine ,Cyst ,General Dentistry ,Retrospective Studies ,business.industry ,Research ,Retrospective cohort study ,030206 dentistry ,Prognosis ,medicine.disease ,CIENCIAS MÉDICAS [UNESCO] ,Surgery ,Otorhinolaryngology ,Maxilla ,Odontogenic Cysts ,UNESCO::CIENCIAS MÉDICAS ,Female ,Oral Surgery ,Neoplasm Recurrence, Local ,medicine.symptom ,business - Abstract
Background To describe epidemiological features of 565 Chinese patients with odontogenic keratocysts (OKC), to investigate possible prognostic factors related to recurrence, and to analyse features of recurrent OKC (rOKC). Material and Methods A retrospective chart review of 565 cases of OKC treated between 2003 and 2015 was undertaken. The probability of recurrence related to prognostic factors including large size, cortical perforation combined with involved teeth in the lumen of the cyst, inflammation, sites of the involved lesion, sex, and daughter cyst variables were analysed. The subsequent relapse of each OKC was compared. Results Patients ranged in age from 7 to 81 years (mean age, 28.4 years) and, of those affected, 66.9% were male and 33.1% were female. Mandibular OKC occurred in 63.01% and 36.99% occurred in the maxilla, 80.53% of patients had non-rOKC, 10.44% rOKC, and 9.03% had multiple OKC lesions. Enucleation with preservation of the involved teeth in the cystic lesion combined with cortical perforation was statistically associated with high recurrence rate, as were daughter cysts, and multilocular lesions. The number of recurrences and the average time (in years) to relapse decreased from the first relapse of OKC to the third relapse, and the difference was significant (P
- Published
- 2019