1. In vivo and in vitro study of co-expression of LMP1 and Cripto-1 in nasopharyngeal carcinoma
- Author
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Qing Ye, Jing Li, Xiaoyan Wang, Xianzeng Zhang, Jun Lin, Yuting Huo, Zhengzhen Sun, Shusen Xie, and Zheng Huang
- Subjects
Carcinoma nasofaríngeo ,LMP1 ,Cripto-1 ,Metástase ,Otorhinolaryngology ,RF1-547 - Abstract
Introduction: Nasopharyngeal carcinoma, an epithelial-derived malignant tumor which because of its anatomical location and atypical early symptoms, when diagnosed invasion and metastasis often have occurred. This requires a better understanding of the development mechanism, identifying diagnostic markers, and developing new treatment strategies. Objective: To study the relationship of LMP1 and Cripto-1 in nasopharyngeal carcinoma. Methods: The expression of LMP1 and Cripto-1 in specimens obtained from nasopharyngeal carcinoma patients (n = 42) and nasopharyngitis patients (n = 22) were examined. The expression of LMP1 and Cripto-1 in LMP1-negative and LMP1-positive (CNE1-LMP1) cells were also examined. Results: The expression of LMP1 and Cripto-1 was significantly higher in nasopharyngeal carcinoma than in nasopharyngitis (p
- Published
- 2020
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