Search

Green extraction of the active lignans from Schisandra chinensis has received considerable attention due to their promising applications in the biomedical field. In this study, microwave‐assisted deep eutectic solvent method was used to simultaneously extract five lignans: Schizandrol A, Schizandrol B, Schisantherin A, Schisandrin A and Schizandrin B. The extraction parameters were optimized according to the calculated comprehensive score obtained from the analytic hierarchy process combined with the entropy weight method. The optimal extraction conditions were that the molar ratio of choline chloride and glycolic acid is 4:1, water content is 30% (V/V), solid–liquid ratio is 1:20 (Wg:VmL), extraction time is 20 min, and extraction temperature is 70°C, under which the extraction rate of the five lignans were 10.89, 8.616, 4.019, 4.893, and 5.318 mg/g. These results confirmed that our extraction method is efficient and feasible for green extraction of lignans from S. chinensis. [ABSTRACT FROM AUTHOR]

Proanthocyanidins-functionalized Fe3O4 @ Ag nanoparticles (Fe3O4 @ AgNPs) were synthesized by one-step hydrothermal method wherein silver nanocrystals were grown in situ on the surface of Fe3O4 nanoparticles with the assistance of proanthocyanidins. The morphology and structure of Fe3O4 @ AgNPs were characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), Fourier-transform infrared spectrometer (FTIR), UV–Vis spectrophotometer (UV–Vis), X-ray powder diffractometer (XRD), and physical property measurement system (PPMS). The characterization results indicated that sliver nanocrystals were deposited on the surface of Fe3O4 nanoparticles to form spherical and uniformly dispersed Fe3O4 @ AgNPs. Moreover, the Fe3O4 @ AgNPs had a high magnetic response, which can be recovered from the environment. The antibacterial activity of the Fe3O4 @ AgNPs against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), and Candida albicans (C. albicans) was investigated. The results confirmed that the Fe3O4 @ AgNPs had broad-spectrum antibacterial activity. At the same time, the adsorption property of the nanoparticles for heavy metal ions Cu2+, Pb2+, and Cd2+ was also studied. The results showed that pH and incubation time played an essential role in the removal of heavy metal ions, and the nanoparticles had excellent removal efficiency. The multifunctional nanomaterial Fe3O4 @ AgNPs prepared by this study have the potential to apply in the biomedical and water disinfection fields. [ABSTRACT FROM AUTHOR]