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2 results on '"Zhi-Xin Mu"'

1. [Experimental study on the pharmacology of 999 ganmaoling, a compound recipe of Chinese and Western materia medica]

Author

Yi-qing, Mao, Zhi-xin, Mu, and Yue-fei, Zhang

Subjects
Male, Chlorpheniramine, Mice, Inbred BALB C, Mice, Inbred ICR, Anti-Inflammatory Agents, Non-Steroidal, Common Cold, Drug Synergism, Rats, Rats, Sprague-Dawley, Drug Combinations, Mice, Caffeine, Animals, Female, Rabbits, Acetaminophen, Drugs, Chinese Herbal
Abstract

To study the pharmacologic characteristics in synergism and complementation of 999 Ganmaoling (GML), a compound recipe composed of Chinese and Western materia medica (CMMWMM), as well as its theoretical basis of matching of Chinese and Western materia medica.The torsion response induced by glacial acetic acid in mice, toe swelling induced by carrageenanin rats, delayed hypersensitive response in mice and fever induced by endotoxin in rats and rabbits were used to comparatively study the actions of CMMWMM in GML. The effect of CMM in antagonizing liver damage caused by WD (acetaminophen) in mice was also studied. RT-PCR method was used to analyze the expression of related cytokines.GML showed a significant antipyretic and analgesic effect, it could inhibit the carrageenan induced inflammation, antagonize the endotoxin induced fever, and promote the amount for expression of cytokines in rats' splenic tissue with pneumococci infection to some extent. The CMM in GML showed certain protective effect on acetaminophen induced liver damage.GML has a potent antipyretic, analgesic and anti-inflammatory effects, CMMWMM in GML showed markedly synergism and complementation, and CMM in it has liver protective effect.

Published
2004

2. Molecular ordering of glycine on Cu(100): The p(2×4) superstructure.

Author

Zhi-Xin Mu, Wei Ji, and Hong Guo

Subjects
*GLYCINE, *COPPER, *DENSITY functionals, *DISPERSION (Chemistry), *CHIRALITY
Abstract

Glycine molecules deposited on a Cu(100) surface give rise to an anisotropic free-electron-like (FEL) electronic dispersion in its p(2×4) superstructure, as reported in recent experiments [ K. Kanazawa et al. Phys. Rev. Lett. 99 216102 (2007); J. Am. Chem. Soc. 129 740 (2007)]. Using density functional theory and exhaustively calculating sixteen possible structures, we have determined the molecular arrangement that can give the experimentally observed FEL behavior. Eight configurations, among the sixteen, were not investigated before in the literature and one of them (denoted Str-3) is able to provide the FEL behavior in excellent agreement with the experiments. In addition, the particular configuration Str-3 satisfies other criteria of the observed p(2×4) superstructure, e.g., chirality and cleavable orientation. [ABSTRACT FROM AUTHOR]

Published
2011
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