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17 results on '"Zhong, Hui-Juan"'

6. Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor.

Author

Shi, Zi‐Yang, Fang, Ying, Xu, Peng‐Peng, Yi, Hong‐Mei, Li, Jian‐Feng, Dong, Yan, Zhu, Yue, Liu, Meng‐Ke, Fu, Di, Wang, Shuo, Shi, Qing, Shen, Rong, Zhong, Hui‐Juan, Wang, Chao‐Fu, Cheng, Shu, Wang, Li, Liu, Feng, and Zhao, Wei‐Li

Subjects
HISTONE deacetylase inhibitors, RITUXIMAB, DECITABINE, LYMPHOMAS, MONONUCLEAR leukocytes, T-cell exhaustion
Abstract

This article discusses a study on double expressor lymphoma (DEL) subtypes and the therapeutic mechanism of epigenetic agents. The study identified three subtypes of DEL with unique characteristics and found that DEL had an inferior survival compared to double negative lymphoma (DNL). The subtypes of DEL were associated with different cell-of-origin and genetic classifications. The study also analyzed the effects of tucidinostat and doxorubicin treatment on different oncogenic transcriptional factors and signaling networks in these subtypes. The results showed distinct molecular heterogeneity and a complex tumor microenvironment in DEL, which contribute to resistance to standard treatment. However, tucidinostat plus doxorubicin demonstrated broad-spectrum sensitivity in vitro and in vivo. The study provides insights for optimizing current treatment paradigms in DEL. [Extracted from the article]

Published
2024
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8. Additional file 1 of Dynamic change of soluble interleukin-2 receptor distinguished molecular heterogeneity and microenvironment alterations in diffuse large B-cell lymphoma

Author

Huo, Yu-Jia, Xu, Peng-Peng, Wang, Li, Zhong, Hui-Juan, Fu, Di, Shi, Qing, Cheng, Shu, Wang, Shuo, Zhang, Mu-Chen, and Zhao, Wei-Li

Abstract

Additional file 1: Supplementary Methods. Figure S1. Dynamic change of sIL-2R in DLBCL. Figure S2. Univariate and multivariate risk models in DLBCL according to sIL-2R dynamic change. Figure S3. Survival analysis in DLBCL according to sIL-2R dynamic change in patients risked by R-IPI. Figure S4. Genetic and lymphoma microenvironment features of sIL-2R subtypes. Table S1. Clinical and pathological characteristics of DLBCL patients. Table S2. Multivariate analysis and C-index for progression-free survival (PFS) and overall survival (OS) in DLBCL. Table S3. Pathway alterations in RES subtype. Table S4. Pathway alterations in RET subtype.

Published
2022
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10. SLC1A1 mediated glutamine addiction and contributed to natural killer T-cell lymphoma progression with immunotherapeutic potential

Author

Xiong, Jie, primary, Wang, Nan, additional, Zhong, Hui-Juan, additional, Cui, Bo-Wen, additional, Cheng, Shu, additional, Sun, Rui, additional, Chen, Jia-Yi, additional, Xu, Peng-Peng, additional, Cai, Gang, additional, Wang, Li, additional, Sun, Xiao-Jian, additional, Huang, Jin-Yan, additional, and Zhao, Wei-Li, additional

Published
2021
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11. Genomic and Transcriptomic Characterization of Natural Killer T Cell Lymphoma

Author

Xiong, Jie, primary, Cui, Bo-Wen, additional, Wang, Nan, additional, Dai, Yu-Ting, additional, Zhang, Hao, additional, Wang, Chao-Fu, additional, Zhong, Hui-Juan, additional, Cheng, Shu, additional, Ou-Yang, Bin-Shen, additional, Hu, Yu, additional, Zhang, Xi, additional, Xu, Bin, additional, Qian, Wen-Bin, additional, Tao, Rong, additional, Yan, Feng, additional, Hu, Jian-Da, additional, Hou, Ming, additional, Ma, Xue-Jun, additional, Wang, Xin, additional, Liu, Yuan-Hua, additional, Zhu, Zun-Min, additional, Huang, Xiao-Bin, additional, Liu, Li, additional, Wu, Chong-Yang, additional, Huang, Li, additional, Shen, Yun-Feng, additional, Huang, Rui-Bin, additional, Xu, Jing-Yan, additional, Wang, Chun, additional, Wu, De-Pei, additional, Yu, Li, additional, Li, Jian-Feng, additional, Xu, Peng-Peng, additional, Wang, Li, additional, Huang, Jin-Yan, additional, Chen, Sai-Juan, additional, and Zhao, Wei-Li, additional

Published
2020
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12. Metformin prolonged the survival of diffuse large B-cell lymphoma and grade 3b follicular lymphoma patients responding to first-line treatment with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone: a prospective phase II clinical trial

Author

Fan, Xing, primary, Zhong, Hui-Juan, additional, Zhao, Bing-Bing, additional, Ou Yang, Bin-Shen, additional, Zhao, Yan, additional, Ye, Jing, additional, Lu, Yi-Ming, additional, Wang, Chao-Fu, additional, Xiong, Hong, additional, Chen, Sai-Juan, additional, Janin, Anne, additional, Wang, Li, additional, and Zhao, Wei-Li, additional

Published
2018
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14. A Phase II Study of Methotrexate, Etoposide, Dexamethasone and Pegaspargase Sandwiched with Radiotherapy in the Treatment of Newly Diagnosed, Stage IE to IIE Extranodal Natural-Killer/T-Cell Lymphoma, Nasal-Type

Author

Xu, Peng-Peng, primary, Xiong, Jie, additional, Cheng, Shu, additional, Zhao, Xia, additional, Wang, Chao-Fu, additional, Cai, Gang, additional, Zhong, Hui-Juan, additional, Huang, Heng-Ye, additional, Chen, Jia-Yi, additional, and Zhao, Wei-Li, additional

Published
2017
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17. MicroRNA-590 Inhibits Lipoprotein Lipase Expression and Prevents Atherosclerosis in apoE Knockout Mice

Author

He, Ping-Ping, primary, OuYang, Xin-Ping, additional, Li, Yuan, additional, Lv, Yun-Cheng, additional, Wang, Zong-Bao, additional, Yao, Feng, additional, Xie, Wei, additional, Tan, Yu-Lin, additional, Li, Liang, additional, Zhang, Min, additional, Lan, Gang, additional, Gong, Duo, additional, Cheng, Hai-Peng, additional, Zhong, Hui-Juan, additional, Liu, Dan, additional, Huang, Chong, additional, Li, Zhao-Xia, additional, Zheng, Xi-Long, additional, Yin, Wei-Dong, additional, and Tang, Chao-Ke, additional

Published
2015
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