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38 results on '"Zhou, Anwei"'

21. A Smart “Energy NanoLock” Selectively Blocks Oral Cancer Energy Metabolism through Synergistic Inhibition of Exogenous Nutrient Supply and Endogenous Energy Production

Author

Xu, Yurui, primary, Zhang, Xiaomin, additional, Zhou, Anwei, additional, Cheng, Can, additional, Chen, Kerong, additional, Zhou, Xinyuan, additional, Zhang, Gui, additional, Ding, Likang, additional, Wu, Xiaotong, additional, Ge, Haixiong, additional, Wu, Heming, additional, and Ning, Xinghai, additional

Published
2022
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23. Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization

Author

Qin, Cheng, Yu, Changshui, Shen, Yaou, Fang, Xiaodong, Chen, Lang, Min, Jiumeng, Cheng, Jiaowen, Zhao, Shancen, Xu, Meng, Luo, Yong, Yang, Yulan, Wu, Zhiming, Mao, Likai, Wu, Haiyang, Ling-Hu, Changying, Zhou, Huangkai, Lin, Haijian, González-Morales, Sandra, Trejo-Saavedra, Diana L., Tian, Hao, Tang, Xin, Zhao, Maojun, Huang, Zhiyong, Zhou, Anwei, Yao, Xiaoming, Cui, Junjie, Li, Wenqi, Chen, Zhe, Feng, Yongqiang, Niu, Yongchao, Bi, Shimin, Yang, Xiuwei, Li, Weipeng, Cai, Huimin, Luo, Xirong, Montes-Hernández, Salvador, Leyva-González, Marco A., Xiong, Zhiqiang, He, Xiujing, Bai, Lijun, Tan, Shu, Tang, Xiangqun, Liu, Dan, Liu, Jinwen, Zhang, Shangxing, Chen, Maoshan, Zhang, Lu, Zhang, Li, Zhang, Yinchao, Liao, Weiqin, Zhang, Yan, Wang, Min, Lv, Xiaodan, Wen, Bo, Liu, Hongjun, Luan, Hemi, Zhang, Yonggang, Yang, Shuang, Wang, Xiaodian, Xu, Jiaohui, Li, Xueqin, Li, Shuaicheng, Wang, Junyi, Palloix, Alain, Bosland, Paul W., Li, Yingrui, Krogh, Anders, Rivera-Bustamante, Rafael F., Herrera-Estrella, Luis, Yin, Ye, Yu, Jiping, Hu, Kailin, and Zhang, Zhiming

Published
2014

29. Designing Porous Antifouling Interfaces for High‐Power Implantable Biofuel Cell

Author

Wang, Lie, primary, He, Er, additional, Gao, Rui, additional, Wu, Xiaotong, additional, Zhou, Anwei, additional, Lu, Jiang, additional, Zhao, Tiancheng, additional, Li, Jiaxin, additional, Yun, Yanjing, additional, Li, Luhe, additional, Ye, Tingting, additional, Jiao, Yiding, additional, Wang, Jiacheng, additional, Chen, Hao, additional, Li, Dan, additional, Ning, Xinghai, additional, Wu, Di, additional, Peng, Huisheng, additional, and Zhang, Ye, additional

Published
2021
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36. Photoactive 3D-Printed Hypertensile Metamaterials for Improving Dynamic Modeling of Stem Cells

Author

Chen, Jianmei, Zhou, Anwei, Nie, Yuanyuan, Chen, Kerong, Zhang, Yu, Xu, Yurui, Kong, Desheng, Shao, Kaifeng, and Ning, Xinghai

Abstract

Current three-dimensional (3D) cell culture systems mainly rely on static cell culture and lack the ability to thoroughly manage cell intrinsic behaviors and biological characteristics, leading to unsatisfied cell activity. Herein, we have developed photoactive 3D-printed hypertensile metamaterials based dynamic cell culture system (MetaFold) for guiding cell fate. MetaFold exhibited high elasticity and photothermal conversion efficiency due to its metapattern architecture and micro/nanoscale polydopamine coating, allowing for responding to mechanical and light stimulation to construct dynamic culture conditions. In addition, MetaFold possessed excellent cell adhesion capability and could promote cell viability and function under dynamic stimulation, thereby maximizing cell activity. Importantly, MetaFold could improve the differentiation efficacy of stem cells into cardiomyocytes and even their maturation, offering high-quality precious candidates for cell therapy. Therefore, we present a dual stimuli-responsive dynamic culture system, which provides a physiologically realistic environment for cell culture and biological study.

Published
2022
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37. Harnessing Nature's ingenuity to engineer butterfly-wing-inspired photoactive nanofiber patches for advanced postoperative tumor treatment.

Author

Zheng H, Chen K, Dun Y, Xu Y, Zhou A, Ge H, Yang Y, and Ning X

Abstract

Postoperative tumor treatment necessitates a delicate balance between eliminating residual tumor cells and promoting surgical wound healing. Addressing this challenge, we harness the innovation and elegance of nature's ingenuity to develop a butterfly-wing-inspired photoactive nanofiber patch (WingPatch), aimed at advancing postoperative care. WingPatch is fabricated using a sophisticated combination of electrostatic spinning and spraying techniques, incorporating black rice powder (BRP) and konjac glucomannan (KGM) into a corn-derived polylactic acid (PLA) nanofiber matrix. This fabrication process yields a paclitaxel-infused porous nanofiber architecture that mirrors the delicate patterns of butterfly wings. Meanwhile, all-natural composites have been selected for their strategic roles in postoperative recovery. BRP offers the dual benefits of photothermal therapy and antibacterial properties, while KGM enhances both antibacterial effectiveness and tissue regeneration. Responsive to near-infrared light, WingPatch ensures robust tissue adhesion and initiates combined photothermal and chemotherapeutic actions to effectively destroy residual tumor cells. Crucially, it simultaneously prevents infections and promotes wound healing throughout the treatment process. Its effectiveness has been confirmed by animal studies, and WingPatch significantly improves treatment outcomes in both breast and liver tumor models. Thus, WingPatch exemplifies our dedication to leveraging natural world's intricate patterns and inventiveness to propel postoperative care forward., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Published
2024
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38. A living neutrophil Biorobot synergistically blocks multifaceted inflammatory pathways in macrophages to effectively neutralize cytokine storm.

Author

Gao Y, Zhou A, Chen K, Zhou X, Xu Y, Wu S, and Ning X

Abstract

Cytokine storm is a potentially life-threatening immune response typically correlated with lung injury, particularly in people with underlying disease states, such as pneumonia. Therefore, the prompt treatment of cytokine storm is essential for successful recovery from a potentially fatal condition. Herein, a living anti-inflammatory Biorobot (firefighter), composed of neutrophils encapsulating mannose-decorated liposomes of the NF-κB inhibitor TPCA-1 and STING inhibitor H-151 (M-Lip@TH, inflammatory retardant), is developed for alleviating hyperinflammatory cytokine storm through targeting multiple inflammatory pathways in macrophages. Biorobot fully inherits the chemotaxis characteristics of neutrophils, and efficiently delivers and releases therapeutic M-Lip@TH at the inflammatory site. Subsequently, M-Lip@TH selectively targets macrophages and simultaneously blocks the transcription factor NF-κB pathway and STING pathway, thereby preventing the overproduction of cytokines. Animal studies show that Biorobot selectively targets LPS-induced acute lung injury, and not only inhibits the NF-κB pathway to suppress the release of various pro-inflammatory cytokines and chemokines, but also blocks the STING pathway to prevent an overactive immune response, which helps to neutralize cytokine storms. Particularly, Biorobot reduces lung inflammation and injury, improves lung function, and increases the survival rates of pneumonia mice. Therefore, Biorobot represents a rational combination therapy against cytokine storm, and may provide insights into the treatment of diseases involving overactive immune responses., Competing Interests: There are no conflicts to declare., (This journal is © The Royal Society of Chemistry.)

Published
2023
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