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Fabry disease (FD) is a rare X chromosome‐linked disorder and can be easily misdiagnosed. Here, we report the case of a 69‐year‐old male patient with FD who developed heart failure and showed extremely high pulmonary artery pressure. His initial symptom was recurrent atrial fibrillation. The left and right atrial inner diameters were large, and the ventricular wall was thick. Gene analysis which showed GLA c.215T>C p.Met72Thr mutation and single photon emission computed tomography indicated the diagnosis of FD with coronary microvascular dysfunction. The patient was prescribed anti‐heart failure drugs, including vericiguat. Following the treatment, his heart function and microvascular perfusion significantly improved, which might be due to the beneficial effects of vericiguat. [ABSTRACT FROM AUTHOR]

We analyzed the differences in knowledge spillover effect between industries by constructing an econometric model. In the model, we measured the relation degree and validity between influencing factors and their influence on knowledge spillover. The result indicates that there is a convergent pattern in the steady state of enterprise knowledge spillover and imitation structure, which formed the screw type advancement of innovation and imitation. Knowledge spillover is influenced by such factors as R&D, trade and traffic condition, labor force mobility, enterprise knowledge absorbency, market mechanism flexibility, time lag of knowledge spillover, and changes of factory site besides trade cost and space-time span. Enterprise knowledge absorbency is proportionate to knowledge spillover. When enterprise knowledge storage quantity disparity is equal to enterprise knowledge absorbency, the knowledge spillover effect is greatest. The time lag of knowledge spillover and the knowledge degeneration rate display inverse ratio with knowledge spillover effect. [ABSTRACT FROM AUTHOR]