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28 results on '"Zhou, Jinlan"'

1. Molecular Evolution and Increasing Macrolide Resistance of Bordetella pertussis, Shanghai, China, 2016-2022

Author

Fu, Pan, Zhou, Jinlan, Yang, Chao, Nijiati, Yaxier, Zhou, Lijun, Yan, Gangfen, Lu, Guoping, Zhai, Xiaowen, and Wang, Chuanqing

Subjects
Nucleotide sequencing -- Analysis -- Genetic aspects, Genomics -- Analysis -- Genetic aspects, Genetic research -- Analysis -- Genetic aspects, Genes -- Genetic aspects -- Analysis, Drug resistance in microorganisms -- Genetic aspects, DNA sequencing -- Analysis -- Genetic aspects, Genomes -- Genetic aspects -- Analysis, Infants -- Analysis, Bordetella pertussis -- Genetic aspects -- Analysis, Public health -- Analysis, RNA -- Analysis -- Genetic aspects, Evolutionary biology -- Genetic aspects -- Analysis, Health
Abstract

Whooping cough (pertussis) is a contagious respiratory illness caused by Bordetella pertussis. The introduction of the whole-cell vaccine (WCV) successfully decreased the incidence of pertussis. Although vaccination has been successful, [...]

Published
2024
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10. IncX3 plasmid-mediated spread of blaNDMgene in Enterobacteriaceae among children in China

Author

Qin, Jie, Wang, Zixuan, Xu, Huihui, Li, Yijia, Zhou, Jinlan, Yaxier, Nijiati, Wang, Chuanqing, and Fu, Pan

Abstract

1.blaNDMis prevalent in carbapenem-resistant Enterobacteriaceae in Chinese children.2.blaNDM-CRE strains pose a great threat to neonates and infants.3.Spread of blaNDMin CREs among children was mainly mediated by the IncX3 plasmid.4.Surveillance on the spread of blaNDMamong Chinese children is very important.

Published
2024
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23. 中国における高齢化の現状と高齢者対策

Author

周, 金蘭, Zhou. Jinlan, 周, 金蘭, and Zhou. Jinlan

Abstract

In China, the proportion of the elderly population over 60 years-old is more than 10% in 2000, and the Chinese have become an aging society. However, there are several problems of this aging society, for example, rapid aging speed, becoming old before rich, and different welfare situation in different provinces. Progress carried out by the Chinese government has done much to solve such problems Due to the increase of the elderly population, the related burdens also raises, such as the economic situation of the elderly, and the health and medical care of the elderly population. In this study, I present the current status of the elderly, their life problems and the related services applied from the government based on in the rapid aging situation.

Published
2015

27. Molecular Evolution and Increasing Macrolide Resistance of Bordetella pertussis, Shanghai, China, 2016-2022.

Author

Fu P, Zhou J, Yang C, Nijiati Y, Zhou L, Yan G, Lu G, Zhai X, and Wang C

Subjects
Child, Infant, Humans, Adolescent, Child, Preschool, China epidemiology, Anti-Bacterial Agents pharmacology, Drug Resistance, Bacterial genetics, Macrolides pharmacology, Evolution, Molecular, Bordetella pertussis genetics, Whooping Cough epidemiology
Abstract

Resurgence and spread of macrolide-resistant Bordetella pertussis (MRBP) threaten global public health. We collected 283 B. pertussis isolates during 2016-2022 in Shanghai, China, and conducted 23S rRNA gene A2047G mutation detection, multilocus variable-number tandem-repeat analysis, and virulence genotyping analysis. We performed whole-genome sequencing on representative strains. We detected pertussis primarily in infants (0-1 years of age) before 2020 and older children (>5-10 years of age) after 2020. The major genotypes were ptxP1/prn1/fhaB3/ptxA1/ptxC1/fim2-1/fim3-1 (48.7%) and ptxP3/prn2/fhaB1/ptxA1/ptxC2/fim2-1/fim3-1 (47.7%). MRBP increased remarkably from 2016 (36.4%) to 2022 (97.2%). All MRBPs before 2020 harbored ptxP1, and 51.4% belonged to multilocus variable-number tandem-repeat analysis type (MT) 195, whereas ptxP3-MRBP increased from 0% before 2020 to 66.7% after 2020, and all belonged to MT28. MT28 ptxP3-MRBP emerged only after 2020 and replaced the resident MT195 ptxP1-MRBP, revealing that 2020 was a watershed in the transformation of MRBP.

Published
2023
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28. [Separation and purification of the main glucosinolate from rapeseeds].

Author

Zhou J, Hu J, and Qiu A

Subjects
Chromatography, Chromatography, High Pressure Liquid, Magnetic Resonance Spectroscopy, Mass Spectrometry, Brassica chemistry, Glucosinolates chemistry, Glucosinolates isolation & purification
Abstract

A procedure for the preparative isolation of 1-S-[(1Z)-3-hydroxy-1-[(sulfooxy) imino]-4-pentenyl]-1-thio-beta-D-glucopyanose, potassium salt (progoitrin) from Brassica oleracea is reported. The major steps in this procedure were: (1) extraction of glucosinolates with methanol from Brassica oleracea; (2) separation and purification of glucosinolates by chromatographic column on alumina support; and (3) a follow-up reversed-phase separation by octadecyl (C18) silica support yielding progoitrin as the main content of glucosinolate. The structure of progoitrin was identified on its physicochemical properties by ultraviolet absorption spectrometry, infrared absorption, 'H nuclear magnetic resonance spectroscopy, mass spectrometry and elemental analysis. Spectroscopic data of the sample isolated were in agreement with those reported in the literature. The purity of progoitrin obtained was determined to be 99% by high performance liquid chromatography. The simplicity of the separation and purification procedure for glucosinolates and the high purity of progoitrin isolated would make the method an important reference for future research on glucosinolates and a favorable technique for future development.

Published
2005

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