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444 results on '"Zhou, Mingyue"'

1. A Model for Analyzing the Behavior of Classroom Teacher-Student Interaction Based on Deep Learning

Author

Zhou, Mingyue, Pan, Wei, Zhang, Zelin, Li, Kan, Editor-in-Chief, Li, Qingyong, Associate Editor, Fournier-Viger, Philippe, Series Editor, Hong, Wei-Chiang, Series Editor, Liang, Xun, Series Editor, Wang, Long, Series Editor, Xu, Xuesong, Series Editor, Guan, Guiyun, editor, Kahl, Christian, editor, Majoul, Bootheina, editor, and Mishra, Deepanjali, editor

Published
2024
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4. Mass cytometry reveals a conserved immune trajectory of recovery in hospitalized COVID-19 patients

Author

Burnett, Cassandra E, Okholm, Trine Line Hauge, Tenvooren, Iliana, Marquez, Diana M, Tamaki, Stanley, Sandoval, Priscila Munoz, Willmore, Andrew, Consortium, The UCSF COMET, Patel, Ravi, Abe-Jones, Yumiko, Asthana, Saurabh, Beagle, Alexander, Bhide, Sharvari, Cai, Cathy, Calvo, Maria, Carrillo, Sidney A, Chak, Suzanna, Collins, Zachary, Darmanis, Spyros, Fragiadakis, Gabriela K, Ghale, Rajani, Giberson, Jeremy, Glenn, Pat, Gonzalez, Ana, Hiam-Galvez, Kamir, Jauregui, Alejandra, Ke, Serena, Lea, Tasha, Lee, Deanna, Lota, Raphael, Lupin-Jimenez, Leonard, Nguyen, Viet, Nigam, Nishita, Pierce, Logan, Prasad, Priya, Rao, Arjun, Rashid, Sadeed, Rodriguez, Nicklaus, Samad, Bushra, Shaw, Cole, Sigman, Austin, Sinha, Pratik, Tang, Kevin, Altamirano, Luz Torres, Tumurbaatar, Erden, Upadhyay, Vaibhav, Ward, Alyssa, Wong, Kristine, Ye, Chun Jimmie, Yee, Kimberly, Zhou, Mingyue, Hendrickson, Carolyn M, Kangelaris, Kirsten N, Langelier, Charles R, Krummel, Matthew F, Woodruff, Prescott G, Calfee, Carolyn S, Erle, David J, Ansel, K Mark, and Spitzer, Matthew H

Subjects
Biomedical and Clinical Sciences, Immunology, Pneumonia & Influenza, Pneumonia, Clinical Research, Lung, Infectious Diseases, Hematology, Aetiology, 2.1 Biological and endogenous factors, Inflammatory and immune system, Good Health and Well Being, COVID-19, Disease Progression, Humans, SARS-CoV-2, UCSF COMET Consortium, disease resolution, immune cell signaling, immune response, recovery
Abstract

While studies have elucidated many pathophysiological elements of COVID-19, little is known about immunological changes during COVID-19 resolution. We analyzed immune cells and phosphorylated signaling states at single-cell resolution from longitudinal blood samples of patients hospitalized with COVID-19, pneumonia and/or sepsis, and healthy individuals by mass cytometry. COVID-19 patients showed distinct immune compositions and an early, coordinated, and elevated immune cell signaling profile associated with early hospital discharge. Intra-patient longitudinal analysis revealed changes in myeloid and T cell frequencies and a reduction in immune cell signaling across cell types that accompanied disease resolution and discharge. These changes, together with increases in regulatory T cells and reduced signaling in basophils, also accompanied recovery from respiratory failure and were associated with better outcomes at time of admission. Therefore, although patients have heterogeneous immunological baselines and highly variable disease courses, a core immunological trajectory exists that defines recovery from severe SARS-CoV-2 infection.

Published
2022

7. Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19

Author

van der Wijst, Monique GP, Vazquez, Sara E, Hartoularos, George C, Bastard, Paul, Grant, Tianna, Bueno, Raymund, Lee, David S, Greenland, John R, Sun, Yang, Perez, Richard, Ogorodnikov, Anton, Ward, Alyssa, Mann, Sabrina A, Lynch, Kara L, Yun, Cassandra, Havlir, Diane V, Chamie, Gabriel, Marquez, Carina, Greenhouse, Bryan, Lionakis, Michail S, Norris, Philip J, Dumont, Larry J, Kelly, Kathleen, Zhang, Peng, Zhang, Qian, Gervais, Adrian, Le Voyer, Tom, Whatley, Alexander, Si, Yichen, Byrne, Ashley, Combes, Alexis J, Rao, Arjun Arkal, Song, Yun S, Fragiadakis, Gabriela K, Kangelaris, Kirsten, Calfee, Carolyn S, Erle, David J, Hendrickson, Carolyn, Krummel, Matthew F, Woodruff, Prescott G, Langelier, Charles R, Casanova, Jean-Laurent, Derisi, Joseph L, Anderson, Mark S, Ye, Chun Jimmie, consortium, on behalf of the UCSF COMET, Abe-Jones, Yumiko, Alvarenga, Bonny, Asthana, Saurabh, Beagle, Alexander, Bhakta, Tanvi, Bhide, Sharvari, Cai, Cathy, Calvo, Maria, Carrillo, Sidney A, Chak, Suzanna, Collins, Zachary, Dandekar, Ravi, Darmanis, Spyros, Esmaili, Armond, Ghale, Rajani, Giberson, Jeremy, Glenn, Pat, Gonzalez, Ana, Jauregui, Alejandra, Jones, Norman, Ke, Serena, Lea, Tasha, Lee, Deanna, Lelidowicz, Aleskandra, Liu, Kathleen, Lota, Raphael, Matthay, Michael, Milush, Jeff, Nguyen, Viet, Nigam, Nishita, Ortiz, Gabe, Pierce, Logan, Prasad, Priya, Rajan, Jayant, Rashid, Ahmad Sadeed, Rodriguez, Nicklaus, Samad, Bushra, Scarlet, Diane, Shaw, Cole, Sigman, Austin, Sinha, Pratik, Spitzer, Matthew, Tang, Kevin, Altamirano, Luz Torres, Tumurbaatar, Erden, Willmore, Andrew, Wilson, Michael, Withers, Reese, Yee, Kimberly, Zamecnik, Colin, Zhan, Jenny, and Zhou, Mingyue

Subjects
Biomedical and Clinical Sciences, Immunology, Coronaviruses, Genetics, Emerging Infectious Diseases, Infectious Diseases, Clinical Research, Lung, Aetiology, 2.1 Biological and endogenous factors, Inflammatory and immune system, Good Health and Well Being, Autoantibodies, COVID-19, Humans, Interferon Type I, UCSF COMET consortium, Biological Sciences, Medical and Health Sciences, Medical biotechnology, Biomedical engineering
Abstract

Neutralizing autoantibodies against type I interferons (IFNs) have been found in some patients with critical coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the prevalence of these antibodies, their longitudinal dynamics across the disease severity scale, and their functional effects on circulating leukocytes remain unknown. Here, in 284 patients with COVID-19, we found type I IFN–specific autoantibodies in peripheral blood samples from 19% of patients with critical disease and 6% of patients with severe disease. We found no type I IFN autoantibodies in individuals with moderate disease. Longitudinal profiling of over 600,000 peripheral blood mononuclear cells using multiplexed single-cell epitope and transcriptome sequencing from 54 patients with COVID-19 and 26 non–COVID-19 controls revealed a lack of type I IFN–stimulated gene (ISG-I) responses in myeloid cells from patients with critical disease. This was especially evident in dendritic cell populations isolated from patients with critical disease producing type I IFN–specific autoantibodies. Moreover, we found elevated expression of the inhibitory receptor leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) on the surface of monocytes isolated from patients with critical disease early in the disease course. LAIR1 expression is inversely correlated with ISG-I expression response in patients with COVID-19 but is not expressed in healthy controls. The deficient ISG-I response observed in patients with critical COVID-19 with and without type I IFN–specific autoantibodies supports a unifying model for disease pathogenesis involving ISG-I suppression through convergent mechanisms.

Published
2021

10. A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling

Author

Abe-Jones, Yumiko, Adkisson, Michael, Ansel, K. Mark, Asthana, Saurabh, Beagle, Alexander, Bhide, Sharvari, Cai, Cathy, Caldera, Saharai, Calvo, Maria, Carrillo, Sidney A., Chak, Suzanna, Christenson, Stephanie, Collins, Zachary, Darmanis, Spyros, Detweiler, Angela, DeVoe, Catherine, Eckalbar, Walter, Giberson, Jeremy, Gonzalez, Ana, Gordon, Gracie, Serpa, Paula Hayakawa, Jauregui, Alejandra, Jones, Chayse, Ke, Serena, Kushnoor, Divya, Lea, Tasha, Lee, Deanna, Leligdowicz, Aleksandra, Liu, Yale, Mahboob, Salman, Maliskova, Lenka, Matthay, Michael, McCarthy, Elizabeth, Muñoz-Sandoval, Priscila, Neff, Norma, Nguyen, Viet, Nigam, Nishita, Parada, Randy, Phelps, Maira, Pierce, Logan, Prasad, Priya, Rashid, Sadeed, Reeder, Gabriella, Rodriguez, Nicklaus, Samad, Bushra, Schroeder, Andrew, Shaw, Cole, Shen, Alan, Sigman, Austin, Sinha, Pratik, Spitzer, Matthew, Sunshine, Sara, Tang, Kevin, Altamirano, Luz Torres, Tsitsiklis, Alexandra, Tumurbaatar, Erden, Upadhyay, Vaibhav, Whatley, Alexander, Willmore, Andrew, Wilson, Michael, Winkler, Juliane, Wong, Kristine, Yee, Kimberly, Yu, Michelle, Zhou, Mingyue, Zhu, Wandi S., Hackney, Jason A., Shivram, Haridha, Vander Heiden, Jason, Overall, Chris, Orozco, Luz, Gao, Xia, Kim, Eugene, West, Nathan, Qamra, Aditi, Chang, Diana, Chakrabarti, Arindam, Choy, David F., Combes, Alexis J., Courau, Tristan, Fragiadakis, Gabriela K., Rao, Arjun Arkal, Ray, Arja, Tsui, Jessica, Hu, Kenneth, Kuhn, Nicholas F., Krummel, Matthew F., Erle, David J., Kangelaris, Kirsten, Sarma, Aartik, Lyon, Zoe, Calfee, Carolyn S., Woodruff, Prescott G., Ghale, Rajani, Mick, Eran, Byrne, Ashley, Zha, Beth Shoshana, Langelier, Charles, Hendrickson, Carolyn M., van der Wijst, Monique G.P., Hartoularos, George C., Grant, Tianna, Bueno, Raymund, Lee, David S., Greenland, John R., Sun, Yang, Perez, Richard, Ogorodnikov, Anton, Ward, Alyssa, Ye, Chun Jimmie, Ramalingam, Thiru, McBride, Jacqueline M., Cai, Fang, Teterina, Anastasia, Bao, Min, Tsai, Larry, Rosas, Ivan O., Regev, Aviv, Kapadia, Sharookh B., Bauer, Rebecca N., and Rosenberger, Carrie M.

Published
2023
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16. An Analysis of the Applicability of Kodaly and Orff Music Pedagogies in Preschool Children’s Music Teaching

Author

Zhou, Mingyue, Striełkowski, Wadim, Editor-in-Chief, Black, Jessica M., Series Editor, Butterfield, Stephen A., Series Editor, Chang, Chi-Cheng, Series Editor, Cheng, Jiuqing, Series Editor, Dumanig, Francisco Perlas, Series Editor, Al-Mabuk, Radhi, Series Editor, Scheper-Hughes, Nancy, Series Editor, Urban, Mathias, Series Editor, Webb, Stephen, Series Editor, Holl, Augustin, editor, Chen, Jun, editor, and Guan, Guiyun, editor

Published
2022
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20. Influence of Fe Substitution into LaCoO3 Electrocatalysts on Oxygen-Reduction Activity

Author

Wang, Maoyu, Han, Binghong, Deng, Junjing, Jiang, Yi, Zhou, Mingyue, Lucero, Marcos, Wang, Yan, Chen, Yubo, Yang, Zhenzhen, N’Diaye, Alpha T, Wang, Qing, Xu, Zhichuan J, and Feng, Zhenxing

Subjects
Macromolecular and Materials Chemistry, Chemical Sciences, Physical Chemistry, Engineering, Materials Engineering, oxygen reduction reaction, X-ray absorption spectroscopy, electronic structure, perovskite, electrocatalyst, Nanoscience & Nanotechnology, Chemical sciences, Physical sciences
Abstract

The development of commercially friendly and stable catalysts for oxygen reduction reaction (ORR) is critical for many energy conversion systems such as fuel cells and metal-air batteries. Many Co-based perovskite oxides such as LaCoO3 have been discovered as the stable and active ORR catalysts, which can be good candidates to replace platinum (Pt). Although researchers have tried substituting various transition metals into the Co-based perovskite catalysts to improve the ORR performance, the influence of substitution on the ORR mechanism is rarely studied. In this paper, we explore the evolution of ORR mechanism after substituting Fe into LaCoO3, using the combination of X-ray photoelectron spectroscopy, high-resolution X-ray microscopy, X-ray diffraction, surface-sensitive soft X-ray absorption spectroscopy characterization, and electrochemical tests. We observed enhanced catalytic activities and increased electron transfer numbers during the ORR in Co-rich perovskite, which are attributed to the optimized eg filling numbers and the stronger hybridization of transition metal 3d and oxygen 2p bands. The discoveries in this paper provide deep insights into the ORR catalysis mechanism on metal oxides and new guidelines for the design of Pt-free ORR catalysts.

Published
2019

24. Tailoring solvation chemistry by hydrogen bonds in carbonate electrolytes for highly stable lithium-metal batteries.

Author

Wu, Jianyang, Zhong, Bing, Zhang, Qiaoli, Zhang, Shuping, Zhang, Xinxiang, Zhang, Zhanjun, Zhou, Mingyue, Liu, Wen, and Zhou, Henghui

Abstract

The application of carbonate electrolytes in lithium-metal batteries (LMBs) has been impeded by low Coulombic efficiency, Li dendrite growth, and an unstable solid electrolyte interphase (SEI). Herein, a facile method is proposed to tailor solvation chemistry in carbonate electrolytes via hydrogen bonds for highly stable LMBs. The inexpensive and eco-friendly urea is used as an additive to promote LiNO3 dissolution and inhibit HF generation in LiPF6-based carbonate electrolytes. LiNO3 facilitates the formation of an N-enriched stable SEI and suppresses the Li dendrite growth, hence improving the compatibility of carbonate electrolytes with Li-metal anodes. The suppression effect on HF generation significantly improves the stability of Ni-rich LiNi0.8Co0.1Mn0.1O2 at both room and elevated temperatures. Benefiting from urea and LiNO3, the designed electrolyte enables a 4.25 V Li‖NCM811 (50 μm thin Li-metal anode and 1.7 mA h cm−2) cell to exhibit excellent cycling stability over 480 cycles with a capacity retention of 70.8% at 0.5C. This work introduces an efficient approach to simultaneously improve the stability of Li-metal anodes, NCM811 cathodes, and LiPF6-based carbonate electrolytes, opening a new avenue for advanced electrolyte design. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Rubus wahlbergii and related species in Sweden.

Author

Zhou, Mingyue, Montes, Melanie S., Mattsson, Tore, Burén, Tomas, Hedrén, Mikael, and Ryde, Ulf

Subjects
*RUBUS, *SPECIES, *MICROSATELLITE repeats, *GLANDS, *PAMPHLETS
Abstract

We studied Rubus wahlbergii and related species in R. sect. Corylifolii, primarily in Sweden, using DNA microsatellites. The results show that the material can be divided into three species: R. wahlbergii s.s. which occurs along the Swedish coast from Bohuslän to Uppland, R. nordicus which occurs on the western coast all the way south to north‐western Skåne, and a previously unrecognized taxon which we here describe as R. wahlbergioides. The latter has scattered localities in Halland, Skåne, Blekinge, Öland and Småland, but is common around Kivik in Skåne and Kalmar in Småland. It is characterised by leaves that are without felt underneath, terminal leaflets with a somewhat more triangular shape and coarser serration than those of R. wahlbergii and also has more glands on the stem and the inflorescence. In the northern part of the distribution, R. nordicus is easily distinguished morphologically from R. wahlbergii, e.g. by a strong tendency to form 7‐foliolate leaves, but in Skåne and Halland, the two species are harder to distinguish. Still, genetically R. nordicus is more similar to R. sordirosanthus than to R. wahlbergii s.s. [ABSTRACT FROM AUTHOR]

Published
2024
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30. Dependency Parsing with Noisy Multi-annotation Data

Author

Zhao, Yu, Zhou, Mingyue, Li, Zhenghua, Zhang, Min, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Zhu, Xiaodan, editor, Zhang, Min, editor, Hong, Yu, editor, and He, Ruifang, editor

Published
2020
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38. Wide‐Range Mode Variable Strategy Design and Switching Process Optimization for LLC Resonant Converter.

Author

Lin, Huipin, Jin, Kai, Xie, Wangjie, Qian, Jiaxin, Li, Ping, Zhou, Mingyue, and Tang, Xiaozhou

Abstract

In response to the demand for new energy applications and wide‐range DC/DC converters, this study focuses on the LLC resonant converter. The traditional LLC working range is not wide enough, so this paper investigates variable mode control to increase the LLC working range without changing the topology. Different control strategies are selected for different modes, and simulation studies are conducted on variable mode control strategies such as full‐bridge frequency conversion, full‐bridge phase shifting, and half‐bridge frequency conversion. The LLC operates in full‐bridge frequency conversion mode at low input voltage, half‐bridge frequency conversion mode at high input voltage, and full‐bridge phase shifting mode at intermediate voltage. The transient process of mode switching is optimized to greatly improve the stability of the converter and reduce voltage fluctuations. Based on the simulation and analysis, the system design of software and hardware is completed, an LLC resonant converter prototype is made, and experimental verification is carried out, confirming the effectiveness of the variable mode strategy. © 2023 Institute of Electrical Engineer of Japan and Wiley Periodicals LLC. [ABSTRACT FROM AUTHOR]

Published
2024
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47. A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling

Author

Hackney, Jason A., primary, Shivram, Haridha, additional, Vander Heiden, Jason, additional, Overall, Chris, additional, Orozco, Luz, additional, Gao, Xia, additional, Kim, Eugene, additional, West, Nathan, additional, Qamra, Aditi, additional, Chang, Diana, additional, Chakrabarti, Arindam, additional, Choy, David F., additional, Combes, Alexis J., additional, Courau, Tristan, additional, Fragiadakis, Gabriela K., additional, Rao, Arjun Arkal, additional, Ray, Arja, additional, Tsui, Jessica, additional, Hu, Kenneth, additional, Kuhn, Nicholas F., additional, Krummel, Matthew F., additional, Erle, David J., additional, Kangelaris, Kirsten, additional, Sarma, Aartik, additional, Lyon, Zoe, additional, Calfee, Carolyn S., additional, Woodruff, Prescott G., additional, Ghale, Rajani, additional, Mick, Eran, additional, Byrne, Ashley, additional, Zha, Beth Shoshana, additional, Langelier, Charles, additional, Hendrickson, Carolyn M., additional, van der Wijst, Monique G.P., additional, Hartoularos, George C., additional, Grant, Tianna, additional, Bueno, Raymund, additional, Lee, David S., additional, Greenland, John R., additional, Sun, Yang, additional, Perez, Richard, additional, Ogorodnikov, Anton, additional, Ward, Alyssa, additional, Ye, Chun Jimmie, additional, Ramalingam, Thiru, additional, McBride, Jacqueline M., additional, Cai, Fang, additional, Teterina, Anastasia, additional, Bao, Min, additional, Tsai, Larry, additional, Rosas, Ivan O., additional, Regev, Aviv, additional, Kapadia, Sharookh B., additional, Bauer, Rebecca N., additional, Rosenberger, Carrie M., additional, Abe-Jones, Yumiko, additional, Adkisson, Michael, additional, Ansel, K. Mark, additional, Asthana, Saurabh, additional, Beagle, Alexander, additional, Bhide, Sharvari, additional, Cai, Cathy, additional, Caldera, Saharai, additional, Calvo, Maria, additional, Carrillo, Sidney A., additional, Chak, Suzanna, additional, Christenson, Stephanie, additional, Collins, Zachary, additional, Darmanis, Spyros, additional, Detweiler, Angela, additional, DeVoe, Catherine, additional, Eckalbar, Walter, additional, Giberson, Jeremy, additional, Gonzalez, Ana, additional, Gordon, Gracie, additional, Serpa, Paula Hayakawa, additional, Jauregui, Alejandra, additional, Jones, Chayse, additional, Ke, Serena, additional, Kushnoor, Divya, additional, Lea, Tasha, additional, Lee, Deanna, additional, Leligdowicz, Aleksandra, additional, Liu, Yale, additional, Mahboob, Salman, additional, Maliskova, Lenka, additional, Matthay, Michael, additional, McCarthy, Elizabeth, additional, Muñoz-Sandoval, Priscila, additional, Neff, Norma, additional, Nguyen, Viet, additional, Nigam, Nishita, additional, Parada, Randy, additional, Phelps, Maira, additional, Pierce, Logan, additional, Prasad, Priya, additional, Rashid, Sadeed, additional, Reeder, Gabriella, additional, Rodriguez, Nicklaus, additional, Samad, Bushra, additional, Schroeder, Andrew, additional, Shaw, Cole, additional, Shen, Alan, additional, Sigman, Austin, additional, Sinha, Pratik, additional, Spitzer, Matthew, additional, Sunshine, Sara, additional, Tang, Kevin, additional, Altamirano, Luz Torres, additional, Tsitsiklis, Alexandra, additional, Tumurbaatar, Erden, additional, Upadhyay, Vaibhav, additional, Whatley, Alexander, additional, Willmore, Andrew, additional, Wilson, Michael, additional, Winkler, Juliane, additional, Wong, Kristine, additional, Yee, Kimberly, additional, Yu, Michelle, additional, Zhou, Mingyue, additional, and Zhu, Wandi S., additional

Published
2023
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