45 results on '"Zhu, Jidong"'
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2. Pharmacological inhibition of SRC-1 phase separation suppresses YAP oncogenic transcription activity
3. Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach
4. Screening inhibitors for blocking UHRF1-methylated DNA interaction with capillary electrophoresis
5. Phase separation underlies signaling activation of oncogenic NTRK fusions
6. Inhibition of cIAP1 as a strategy for targeting c-MYC–driven oncogenic activity
7. Discovery of new small molecule inhibitors targeting isocitrate dehydrogenase 1 (IDH1) with blood-brain barrier penetration
8. Selenocysteine-Specific Mass Spectrometry Reveals Tissue-Distinct Selenoproteomes and Candidate Selenoproteins
9. Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy
10. Modeling tumor development and metastasis using paired organoids derived from patients with colorectal cancer liver metastases
11. Accurate and efficient interpretation of quantitative amino-acid attribution for disordered proteins undergoing LLPS
12. Discovery of novel 1,2,3,4-tetrahydrobenzo[4, 5]thieno[2, 3-c]pyridine derivatives as potent and selective CYP17 inhibitors
13. GluN2A-selective positive allosteric modulator-nalmefene-flumazenil reverses ketamine-fentanyl-dexmedetomidine-induced anesthesia and analgesia in rats
14. Small Molecule Degraders Targeting the SHP2E76A Mutant Effectively Inhibiting the Proliferation of Wild-type and Mutant SHP2 Dependent Tumor Cells
15. Somatic Ras/Raf/MAPK Variants Enriched in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy
16. Phase separation ability and phosphatase activity of the SHP1-R360E mutant
17. Activation of PI3K/Akt and MAPK Pathways Regulates Myc-Mediated Transcription by Phosphorylating and Promoting the Degradation of Mad1
18. Abstract 326: Structural dynamics-based hit generation to disrupt YAP/TAZ-TEAD protein-protein interaction
19. Abstract 1475: Discovery of ETS-001, a highly potent allosteric SHP2 inhibitor to treat RTK/RAS-driven cancers
20. An Artemisinin Derivative ART1 Induces Ferroptosis by Targeting the HSD17B4 Protein Essential for Lipid Metabolism and Directly Inducing Lipid Peroxidation
21. Rational design of a potent macrocyclic peptide inhibitor targeting the PD-1/PD-L1 protein–protein interaction
22. A novel partially open state of SHP2 points to a “multiple gear” regulation mechanism
23. Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation
24. Effective approach to ureas through organocatalyzed one-pot process
25. Novel Triapine Derivative Induces Copper-Dependent Cell Death in Hematopoietic Cancers
26. Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment
27. Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment
28. Discovery of novel 1,2,3,4-tetrahydrobenzo[4, 5]thieno[2, 3- c ]pyridine derivatives as potent and selective CYP17 inhibitors
29. Researches on the Space-Time View of the Special Relativity
30. A New Understanding of Equivalence of the Accelerating Field and the Gravitational Field
31. Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53
32. ChemInform Abstract: Radical‐Induced Metal‐Free Alkynylation of Aldehydes by Direct C—H Activation
33. ChemInform Abstract: Fluorination of 2-Substituted Benzo[b]furans with Selectfluor.
34. Radical-Induced Metal-Free Alkynylation of Aldehydes by Direct CH Activation
35. Fluorination of 2-substituted benzo[b]furans with Selectfluor™
36. Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia
37. Structure of Human SMYD2 Protein Reveals the Basis of p53 Tumor Suppressor Methylation
38. c-IAP1 Cooperates with Myc by Acting as a Ubiquitin Ligase for Mad1
39. Synthetic Studies Toward Two Marine Cyclic Peptides
40. Total Synthesis of Microsclerodermin E.
41. Total Synthesis of Microsclerodermin E
42. A Lawful Act.
43. Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53.
44. RNA-Guided DNA Transposition in Corynebacterium glutamicum and Bacillus subtilis .
45. Radical-induced metal-free alkynylation of aldehydes by direct C-H activation.
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