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Your search keyword '"Zhu, Xinsheng"' showing total 332 results
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332 results on '"Zhu, Xinsheng"'

1. Neoadjuvant camrelizumab (an anti-PD-1 antibody) plus chemotherapy or apatinib (a VEGFR-2 inhibitor) for initially unresectable stage II–III non-small-cell lung cancer: a multicentre, two-arm, phase 2 exploratory study

Author

Xia, Haoran, Zhang, Han, Ruan, Zheng, Zhang, Huibiao, Sun, Liangdong, Chen, Hezhong, Zhou, Yongxin, Zhang, Lele, Bian, Dongliang, Zhu, Xinsheng, Zhang, Jing, Sun, Fenghuan, Yu, Huansha, Song, Nan, Liu, Xiaogang, Zhu, Yuming, Zhang, Haiping, He, Wenxin, Chen, Jian, Yang, Jie, Chen, Guohan, Xie, Shiliang, Tang, Dongfang, Zhang, Xiaomiao, Duan, Liang, Zhao, Deping, Li, Qinchuan, Zhang, Peng, and Jiang, Gening

Published
2024
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9. Safety and effectiveness of neoadjuvant PD-1 inhibitor (toripalimab) plus chemotherapy in stage II–III NSCLC (LungMate 002): an open-label, single-arm, phase 2 trial

Author

Zhu, Xinsheng, Sun, Liangdong, Song, Nan, He, Wenxin, Xie, Boxiong, Hu, Junjie, Zhang, Jing, Yang, Jie, Dai, Jie, Bian, Dongliang, Xia, Haoran, Sun, Fenghuan, Xiong, Anwen, Luo, Jie, Zhang, Lele, Yu, Huansha, Liu, Ming, Liu, Hongcheng, Wang, Haifeng, Zhang, Haiping, Chen, Chang, Wu, Chunyan, Duan, Liang, Zhu, Yuming, Zhang, Peng, and Jiang, Gening

Published
2022
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10. Facilitating Charge Separation of Donor–Acceptor Conjugated Microporous Polymers via Position Isomerism Strategy for Efficient CO 2 Photoconversion.

Author

Wang, Dandan, Yan, Xiaofei, Zhu, Xinsheng, Liu, Ying, Zhang, Laihong, Lu, Yaqiu, Li, Jie, and Xue, Dingming

Abstract

Photoreduction of CO2 into the chemical feedstocks of fuels provides a green way to help solve both the energy crisis and carbon emission issues. Nevertheless, undesirable charge separation and migration, as well as rapid reverse charge recombination results in the unsatisfactory photocatalytic activity of most conjugated microporous polymers (CMPs). Herein, a pair of donor–acceptor (D-A) CMPs for CO2 photoconversion was developed through position isomerism by altering linkage sites. The results show that Py-D27F with 2,7-site linkage exhibits a completely conjugated structure and a large molecular dipole moment, thus significantly accelerating charge separation and transfer. As a result, Py-D27F achieves a higher yield of 320.9 μmol g−1 h−1 for CO2-to-CO photoreduction (without the addition of any photosensitizers and precious metals), which is about three-fold greater than that of Py-D36F (3,6-site linkage). This study provides a valuable idea for exploring outstanding CMP photocatalysts for the efficient processing of photocatalysis. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Machine Learning-Assisted Prognostic Model Reveals EMT-Mediated Chemoresistance Overcome by TGF-β Inhibition in Lung Squamous Cell Carcinoma

Author

Sun, Liangdong, primary, Wang, Jue, additional, Yu, Huansha, additional, Zhu, Xinsheng, additional, Zhang, Jing, additional, Hu, Junjie, additional, Yan, Yilv, additional, Zhang, Xun, additional, Zhu, Yuming, additional, Jiang, Gening, additional, Ding, Ming, additional, Zhang, Peng, additional, and Zhang, Lele, additional

Published
2024
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27. MAZ promotes tumor proliferation and immune evasion in lung adenocarcinoma

Author

Chen, Yan, Zhu, Xinsheng, Wang, Jue, Hu, Junjie, Zhang, Jing, Zhang, Xun, Han, Lu, Yu, Huansha, Hu, Haiyang, Fei, Ke, Zhang, Peng, and Zhang, Lele

Abstract

Lung adenocarcinoma (LUAD) is the most dominant histological subtype of lung cancer and one of the most lethal malignancies. The identification of novel therapeutic targets is required for the treatment of LUAD. Here, we showed that MYC-associated zinc-finger protein (MAZ) is upregulated in LUAD tissues. MAZ expression levels are inversely correlated with patient survival. Silencing of MAZ decreased tumor proliferation and the expression of pro-tumorigenic chemokines and Galectin-9 (Gal-9), an immune checkpoint molecule. The pro-tumorigenic chemokines and Gal-9 induce immune suppression by recruitment of myeloid cells and inhibition of T cell activation, respectively. Mechanistically, MAZ transcriptionally regulates KRAS expression and activates its downstream AKT-NF-κB signaling pathway, which is crucial for tumor progression and immune evasion. Additionally, in vivo animal models and bioinformatic analyses indicated that MAZ suppression could enhance the efficacy of immune checkpoint blockade (ICB) therapy for LUAD. Overall, our results suggest that MAZ plays an important role in regulating cell proliferation and immune evasion via KRAS/AKT/NF-κB signaling in LUAD. Our findings offer a candidate molecular target for LUAD therapy, with implications for improving the efficacy of ICB therapy.

Published
2024
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31. Additional file 2 of Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing

Author

Hu, Junjie, Zhang, Lele, Xia, Haoran, Yan, Yilv, Zhu, Xinsheng, Sun, Fenghuan, Sun, Liangdong, Li, Shuangyi, Li, Dianke, Wang, Jin, Han, Ya, Zhang, Jing, Bian, Dongliang, Yu, Huansha, Chen, Yan, Fan, Pengyu, Ma, Qiang, Jiang, Gening, Wang, Chenfei, and Zhang, Peng

Abstract

Additional file 2: Fig. S1. Sample collection, single-cell clustering and marker gene visualization for major lineages. Fig. S2. Immunohistochemistry (IHC) staining of immune cells. Fig. S3. Cluster marker genes, tumor cell identification, cellular fractions and hematoxylin eosin (H&E) staining for epithelial cells. Fig. S4. Upregulated genes and signatures for malignant cells among TN, MPR and NMPR patients and serum estradiol dynamics. Fig. S5. Marker genes, differentially expressed genes and RNA velocity for T/NK subsets. Fig. S6. Marker genes, immunofluorescence, and Nichenet analysis for B-cell subsets. Fig. S7. Marker genes and survival analysis for myeloid subsets. Fig. S8. Monocle, SCENIC and cellular fraction analysis for neutrophil subsets.

Published
2023
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32. Additional file 1 of Safety and effectiveness of neoadjuvant PD-1 inhibitor (toripalimab) plus chemotherapy in stage II–III NSCLC (LungMate 002): an open-label, single-arm, phase 2 trial

Author

Zhu, Xinsheng, Sun, Liangdong, Song, Nan, He, Wenxin, Xie, Boxiong, Hu, Junjie, Zhang, Jing, Yang, Jie, Dai, Jie, Bian, Dongliang, Xia, Haoran, Sun, Fenghuan, Xiong, Anwen, Luo, Jie, Zhang, Lele, Yu, Huansha, Liu, Ming, Liu, Hongcheng, Wang, Haifeng, Zhang, Haiping, Chen, Chang, Wu, Chunyan, Duan, Liang, Zhu, Yuming, Zhang, Peng, and Jiang, Gening

Abstract

Additional file 1: Table S1. Inclusion and exclusion criteria.

Published
2023
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33. Additional file 4 of Safety and effectiveness of neoadjuvant PD-1 inhibitor (toripalimab) plus chemotherapy in stage II–III NSCLC (LungMate 002): an open-label, single-arm, phase 2 trial

Author

Zhu, Xinsheng, Sun, Liangdong, Song, Nan, He, Wenxin, Xie, Boxiong, Hu, Junjie, Zhang, Jing, Yang, Jie, Dai, Jie, Bian, Dongliang, Xia, Haoran, Sun, Fenghuan, Xiong, Anwen, Luo, Jie, Zhang, Lele, Yu, Huansha, Liu, Ming, Liu, Hongcheng, Wang, Haifeng, Zhang, Haiping, Chen, Chang, Wu, Chunyan, Duan, Liang, Zhu, Yuming, Zhang, Peng, and Jiang, Gening

Abstract

Additional file 4: Table S3. Comparison of perioperative outcomes between the VATS group and the thoracotomy group.

Published
2023
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34. H

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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35. F

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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36. Z

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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37. I

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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38. C

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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39. E

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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40. G

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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41. Y

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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42. B

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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43. D

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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44. U

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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45. W

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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46. X

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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47. Q

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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48. R

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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49. V

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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50. A

Author

Yang, Xinrong, Chen, Anmin, Ma, Yingfu, Gao, Yuan, Gao, Zhemin, Fu, Bingyi, Sun, Fang, Qiao, Jinlin, Li, Quan, Wan, Shuqian, Werner, Hermut, Chuang, Yinfu, Zhu, Xinsheng, Yang, Xinrong, editor, Chen, Anmin, editor, Ma, Yingfu, editor, Gao, Yuan, editor, Gao, Zhemin, editor, Fu, Bingyi, editor, Sun, Fang, editor, Qiao, Jinlin, editor, Li, Quan, editor, Wan, Shuqian, editor, Werner, Hermut, editor, Chuang, Yinfu, editor, and Zhu, Xinsheng, editor

Published
2003
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