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Nickel-rich layered oxide cathode materials for advanced lithium-ion batteries have received much attention recently because of their high specific capacities and significant reduction of cost. However, these cathodes are facing a fundamental challenge of loss in performance as a result of surface lithium residue, side reactions with the electrolyte and structure rearrangement upon long-term cycling. Herein, by capturing the lithium residue on the surface of LiNi0.8Co0.1Mn0.1O2 (NCM) cathode material as Li source, we propose a hybrid coating strategy incorporating lithium ions conductor LixAlO2 with superconductor LixTi2O4 to overcome those obstinate issues. By taking full advantage of this unique hybrid nanomembrane coating architecture, both the lithium ion diffusion ability and electronic conductivity of LiNi0.8Co0.1Mn0.1O2 cathode material are improved, resulting in remarkably enhanced electrochemical performances during high voltage operation, including good cycle performance, high reversible capacit...

LiNi0.8Co0.15Al0.05O2 (NCA) is one of the most promising cathode material for lithium-ion batteries (LIBs) in electric vehicles, which is successfully adopted in Tesla. However, the dissolution of the cation into the electrolyte is still a one of the major challenges (fading capacity and poor cyclability, etc.) presented in pristine NCA. Herein, a homogeneous nanoscale ZnO film is directly sputtered on the surface of NCA electrode via the magnetron sputtering (MS). This ZnO film is evidenced by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). The results clearly demonstrate that ZnO film is fully and uniformly covered on the NCA electrodes. After 90 cycles at 1.0C, the optimized MS-2min coated NCA electrode delivers much higher discharge capacity with 169 mAh g−1 than that of the pristine NCA electrode with 127 mAh g−1. In addition, the discharge capacity also reaches 166 mAh g−1 at 3.0C, as compared to that of 125 mAh g−1 for the pristine electrode. The improved electrochemical performance can be ascribed to the superiority of the MS ZnO film that reduce charge transfer resistance and protect the NCA electrode from cation dissolution.

Both coronavirus disease 2019 (COVID-19) and severe acute respiratory syndrome (SARS) are epidemic, contagious, sudden, and publicly harmful diseases. The whole-genome nucleotide identity of the pathogens causing the two diseases reached 79.5%. The mechanism and treatment of COVID-19 are still under investigation. Combining the experiences of SARS prevention and treatment in 2003, and the case data and literature of COVID-19, the similarities and differences between the two diseases in terms of causes, susceptible people, characteristics, dialectical mode, and treatment were analyzed. The two diseases are both plagues in terms of Chinese medicine. The cause of SARS was “heat poison,” and its pathogenesis was “heat poison, stasis, and qi and yin deficiency.” Therefore the treatment regimen was mainly to clear away heat, detoxicate, and expel evil. While the cause of COVID-19 was “wet poison,” and its pathogenesis was “wet, poison, heat, stasis, close, syncope, and yang collapse.” Hence the basic treatment strategy was to declare lung and remove dampness. Treatment of COVID-19 was clearing away evil qi as soon as possible, with the basic treatment regimen, which was declaring lung, removing dampness, and dispelling the evil. Combined with Traditional Chinese medicine's (TCM's) understanding and experience in SARS prevention and treatment, and Chinese clinical cured cases, we try to provide strategies for people all over the world to understand and respond to COVID-19, through the analysis and comparison. To improve COVID-19 prevention and treatment regimen and give full play to the advantages of TCM.

Objective: Based on data mining technology, we attempted to explore the medication rules of modern traditional Chinese medicine (TCM) compounds in non-small cell lung cancer (NSCLC) treatment, to provide a reference for clinical drug use. Methods: From 2010 to 2017, TCM compounds used for NSCLC treatment were collected from the Beijing 301 Hospital. The modern TCM compounds utilized in the treatment of NSCLC were established in the prescription database. Excel, SPSS 22, and SPSS Modeler14.2 software were utilized for the frequency analysis, factor analysis, cluster analysis, and association analysis. Then, the quantitative and qualitative analyses of the regularity of TCM compound medications were performed, and the possible mechanism was discussed. Results: The treatment of NSCLC using Chinese herbal compounds involved 231 prescriptions, 389 types of Chinese herbs, and 135 types of high-frequency Chinese herbs. Of these, Fritillaria cirrhosa, stir-baked fried Scutellariae, raw Os Draconis, Poria cocos (Schw.) Wolf, and Scutellaria barbata were the top five frequently prescribed Chinese herbs. Among the 39 types of drugs, heat-clearing and detoxifying drugs and qi-tonifying drugs were the leading. Cold, warm, flat, slightly cold, sweet, bitter, and pungent of four properties and five tastes and the meridians of lung, spleen, and stomach were most commonly selected. Factor analysis extracted 12 common factors, and the cumulative contribution rate was 65.595%, which mainly contained tonifying qi and blood; tonifying yin, clearing away heat, and eliminating stagnation; tonifying the spleen, regulating qi, and eliminating phlegm. Forty drug groups were obtained by cluster analysis; a total of 63 association rules were obtained by association analysis. The pairs of Poria cocos → dried tangerine peel and fried Atractylodes macrocephala → dried tangerine peel were commonly used in NSCLC, while the three most frequent herb groups were raw Astragalus → fried A. macrocephala and Poria cocos; raw-medicated leaven → fried A. macrocephala and Poria cocos; and dried tangerine peel → fried A. macrocephala and Poria cocos. Conclusion: Lung cancer is mainly caused by qi stagnation, phlegm obstruction, phlegm, and blood stasis. Based on the principle of strengthening the body and dispelling pathogens, clinical treatment of NSCLC involves clearing heat and detoxifying, tonifying the spleen, regulating qi, eliminating phlegm to dispel pathogens, and tonifying qi and blood to strengthen the body.

The paper is concerned with changes of acidity and the amount of microorganism in China Northeast sauerkraut fermentationin.It studies the effect of lactic acid bacteria, culture temperature and the concentration of sodium chloride on sauerkraut acidity ,microbial number, vitamin C and nitrite content .Methods of natural traditional fermentation sauerkraut and artificial inoculating lactic acid bacteria fermentation sauerkraut are compared,the results show artificial inoculating fermentation sauerkraut can effectively prevent the growth of harmful bacteria and inhibit formation of carcinogens such as nitrite,avoid some shortcomings in Chinese cabbage natural fermentation process.

Zeolite NaKL was in-situ crystallized under static condition with kaolin microspheres calcined at 980 °C as silicon and aluminium sources. Influences of hydrothermal synthesis conditions such as the mole ratio of n(K2O)/n(Na2O), n(OH-)/n(SiO2) and crystallizaion time on crystallization of zeolite L were studied in detail. The crystal phase and morphology of the as-prepared zeolite samples were characterized by X-ray diffraction (XRD) and scanning electronic microscopy (SEM). The results showed that the as-synthesized samples owned characteristic peaks of zeolite L with high crystallinity and were covered uniformly by regular crystal of zeolite L on its kaolin microsphere surface , which maintained complete ball shape as before. The optimum conditions to get zeolite NaKL with high crystallinity by this method were found to be the mole ratio of n(K2O)/n(Na2O) =7:3 and n(OH-)/n(SiO2) =0.50 in the reaction mixture, an aging of the reactants at room temperature for 30 h and crystallization temperature 120 °C for 24 h.

To construct a eukaryotic expression vector encoding the gene of extracellular region of type II transforming growth factor beta receptor (sTGFbetaR II), to express the protein in CHO cell line and to determine its biological activity.The extracellular region (amino acids 1-159) of the human TGFbetaR II cDNA was amplified by PCR from a TGFbetaR II chimeric plasmid,and the eukaryotic expression plasmid pCDNA3.1/myc-his(-)B-sTGFbetaR II(pCDNA-sTGFbetaR II) was constructed by inserting the sTGFbetaR II cDNA into the EcoR I/Hind III-digested pCDNA. The DNA sequence was confirmed by double digestion and the pCDNA-sTGFbetaR II plasmid was transfected into the CHO cell line. The sTGFbetaR II protein was confirmed by Western blotting analysis and its biological function was determined.The specific protein was observed in western blotting, and the protein abrogated the growth-inhibitory effects of TGF-beta1 on mink lung epithelial cells (Mv1Lu).The eukaryotic expression plasmid pCDNA-sTGFbetaR II has been successfully constructed and the sTGFsTGFbetaR II protein with biological activity obtained.