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1. The THESEUS space mission concept: science case, design and expected performances

Author

Amati, L., O'Brien, P., Goetz, D., Bozzo, E., Tenzer, C., Frontera, F., Ghirlanda, G., Labanti, C., Osborne, J. P., Stratta, G., Tanvir, N., Willingale, R., Attina, P., Campana, R., Castro-Tirado, A. J., Contini, C., Fuschino, F., Gomboc, A., Hudec, R., Orleanski, P., Renotte, E., Rodic, T., Bagoly, Z., Blain, A., Callanan, P., Covino, S., Ferrara, A., Floch, E. Le, Marisaldi, M., Mereghetti, S., Rosati, P., Vacchi, A., D'Avanzo, P., Giommi, P., Piranomonte, S., Piro, L., Reglero, V., Rossi, A., Santangelo, A., Salvaterra, R., Tagliaferri, G., Vergani, S., Vinciguerra, S., Briggs, M., Campolongo, E., Ciolfi, R., Connaughton, V., Cordier, B., Morelli, B., Orlandini, M., Adami, C., Argan, A., Atteia, J. -L., Auricchio, N., Balazs, L., Baldazzi, G., Basa, S., Basak, R., Bellutti, P., Bernardini, M. G., Bertuccio, G., Braga, J., Branchesi, M., Brandt, S., Brocato, E., Budtz-Jorgensen, C., Bulgarelli, A., Burderi, L., Camp, J., Capozziello, S., Caruana, J., Casella, P., Cenko, B., Chardonnet, P., Ciardi, B., Colafrancesco, S., Dainotti, M. G., D'Elia, V., De Martino, D., De Pasquale, M., Del Monte, E., Della Valle, M., Drago, A., Evangelista, Y., Feroci, M., Finelli, F., Fiorini, M., Fynbo, J., Gal-Yam, A., Gendre, B., Ghisellini, G., Grado, A., Guidorzi, C., Hafizi, M., Hanlon, L., Hjorth, J., Izzo, L., Kiss, L., Kumar, P., Kuvvetli, I., Lavagna, M., Li, T., Longo, F., Lyutikov, M., Maio, U., Maiorano, E., Malcovati, P., Malesani, D., Margutti, R., Martin-Carrillo, A., Masetti, N., McBreen, S., Mignani, R., Morgante, G., Mundell, C., Nargaard-Nielsen, H. U., Nicastro, L., Palazzi, E., Paltani, S., Panessa, F., Pareschi, G., Pe'er, A., Penacchioni, A. V., Pian, E., Piedipalumbo, E., Piran, T., Rauw, G., Razzano, M., Read, A., Rezzolla, L., Romano, P., Ruffini, R., Savaglio, S., Sguera, V., Schady, P., Skidmore, W., Song, L., Stanway, E., Starling, R., Topinka, M., Troja, E., van Putten, M., Vanzella, E., Vercellone, S., Wilson-Hodge, C., Yonetoku, D., Zampa, G., Zampa, N., Zhang, B., Zhang, B. B., Zhang, S., Zhang, S. -N., Antonelli, A., Bianco, F., Boci, S., Boer, M., Botticella, M. T., Boulade, O., Butler, C., Campana, S., Capitanio, F., Celotti, A., Chen, Y., Colpi, M., Comastri, A., Cuby, J. -G., Dadina, M., De Luca, A., Dong, Y. -W., Ettori, S., Gandhi, P., Geza, E., Greiner, J., Guiriec, S., Harms, J., Hernanz, M., Hornstrup, A., Hutchinson, I., Israel, G., Jonker, P., Kaneko, Y., Kawai, N., Wiersema, K., Korpela, S., Lebrun, V., Lu, F., MacFadyen, A., Malaguti, G., Maraschi, L., Melandri, A., Modjaz, M., Morris, D., Omodei, N., Paizis, A., Pata, P., Petrosian, V., Rachevski, A., Rhoads, J., Ryde, F., Sabau-Graziati, L., Shigehiro, N., Sims, M., Soomin, J., Szecsi, D., Urata, Y., Uslenghi, M., Valenziano, L., Vianello, G., Vojtech, S., Watson, D., and Zicha, J.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

THESEUS is a space mission concept aimed at exploiting Gamma-Ray Bursts for investigating the early Universe and at providing a substantial advancement of multi-messenger and time-domain astrophysics. These goals will be achieved through a unique combination of instruments allowing GRB and X-ray transient detection over a broad field of view (more than 1sr) with 0.5-1 arcmin localization, an energy band extending from several MeV down to 0.3 keV and high sensitivity to transient sources in the soft X-ray domain, as well as on-board prompt (few minutes) follow-up with a 0.7 m class IR telescope with both imaging and spectroscopic capabilities. THESEUS will be perfectly suited for addressing the main open issues in cosmology such as, e.g., star formation rate and metallicity evolution of the inter-stellar and intra-galactic medium up to redshift $\sim$10, signatures of Pop III stars, sources and physics of re-ionization, and the faint end of the galaxy luminosity function. In addition, it will provide unprecedented capability to monitor the X-ray variable sky, thus detecting, localizing, and identifying the electromagnetic counterparts to sources of gravitational radiation, which may be routinely detected in the late '20s / early '30s by next generation facilities like aLIGO/ aVirgo, eLISA, KAGRA, and Einstein Telescope. THESEUS will also provide powerful synergies with the next generation of multi-wavelength observatories (e.g., LSST, ELT, SKA, CTA, ATHENA)., Comment: Accepted for publication in Advances in Space Research. Partly based on the proposal submitted on October 2016 in response to the ESA Call for next M5 mission, with expanded and updated science sections

Published
2017
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2. New Exclusion Limits for the Search of Scalar and Pseudoscalar Axion-Like Particles from 'Light Shining Through a Wall'

Author

Ballou, R., Deferne, G., Finger Jr., M., Finger, M., Flekova, L., Hosek, J., Kunc, S., Macuchova, K., Meissner, K. A., Pugnat, P., Schott, M., Siemko, A., Slunecka, M., Sulc, M., Weinsheimer, C., and Zicha, J.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

Physics beyond the Standard Model predicts the possible existence of new particles that can be searched at the low energy frontier in the sub-eV range. The OSQAR photon regeneration experiment looks for "Light Shining through a Wall" from the quantum oscillation of optical photons into "Weakly Interacting Sub-eV Particles", such as axion or Axion-Like Particles (ALPs), in a 9 T transverse magnetic field over the unprecedented length of $2 \times 14.3$ m. In 2014, this experiment has been run with an outstanding sensitivity, using an 18.5 W continuous wave laser emitting in the green at the single wavelength of 532 nm. No regenerated photons have been detected after the wall, pushing the limits for the existence of axions and ALPs down to an unprecedented level for such a type of laboratory experiment. The di-photon couplings of possible pseudo-scalar and scalar ALPs can be constrained in the nearly massless limit to be less than $3.5\cdot 10^{-8}$ GeV$^{-1}$ and $3.2\cdot 10^{-8}$ GeV$^{-1}$, respectively, at 95% Confidence Level., Comment: 6 pages, 6 figures

Published
2015
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3. Latest Results of the OSQAR Photon Regeneration Experiment for Axion-Like Particle Search

Author

Ballou, R., Deferne, G., Duvillaret, L., Finger, Jr., M., Finger, M., Flekova, L., Hosek, J., Husek, T., Jary, V., Jost, R., Kral, M., Kunc, S., Macuchova, K., Meissner, K. A., Morville, J., Pugnat, P., Romanini, D., Schott, M., Siemko, A., Slunecka, M., Sulc, M., Vitrant, G., Weinsheimer, C., and Zicha, J.

Subjects
High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics, High Energy Physics - Phenomenology, Physics - Instrumentation and Detectors
Abstract

The OSQAR photon regeneration experiment searches for pseudoscalar and scalar axion-like particles by the method of "Light Shining Through a Wall", based on the assumption that these weakly interacting sub-eV particles couple to two photons to give rise to quantum oscillations with optical photons in strong magnetic field. No excess of events has been observed, which constrains the di-photon coupling strength of both pseudoscalar and scalar particles down to $5.7 \cdot 10^{-8}$ GeV$^{-1}$ in the massless limit. This result is the most stringent constraint on the di-photon coupling strength ever achieved in laboratory experiments., Comment: 6 pages, 5 figures. appears in Proceedings of the 10th PATRAS Workshop on Axions, WIMPs and WISPs (2014)

Published
2014

4. Search for weakly interacting sub-eV particles with the OSQAR laser-based experiment: results and perspectives

Author

Pugnat, P., Ballou, R., Schott, M., Husek, T., Sulc, M., Deferne, G., Duvillaret, L., Finger Jr., M., Finger, M., Flekova, L., Hosek, J., Jary, V., Jost, R., Kral, M., Kunc, S., Macuchova, K., Meissner, K. A., Morville, J., Romanini, D., Siemko, A., Slunecka, M., Vitrant, G., and Zicha, J.

Subjects
High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics, High Energy Physics - Phenomenology
Abstract

Recent theoretical and experimental studies highlight the possibility of new fundamental particle physics beyond the Standard Model that can be probed by sub-eV energy experiments. The OSQAR photon regeneration experiment looks for "Light Shining through a Wall" (LSW) from the quantum oscillation of optical photons into "Weakly Interacting Sub-eV Particles" (WISPs), like axion or axion-like particles (ALPs), in a 9 T transverse magnetic field over the unprecedented length of $2 \times 14.3$ m. No excess of events has been detected over the background. The di-photon couplings of possible new light scalar and pseudo-scalar particles can be constrained in the massless limit to be less than $8.0\times10^{-8}$ GeV$^{-1}$. These results are very close to the most stringent laboratory constraints obtained for the coupling of ALPs to two photons. Plans for further improving the sensitivity of the OSQAR experiment are presented., Comment: 7 pages, 7 figures

Published
2013
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5. The THESEUS space mission concept: science case, design and expected performances

Author

Amati, L., O’Brien, P., Götz, D., Bozzo, E., Tenzer, C., Frontera, F., Ghirlanda, G., Labanti, C., Osborne, J.P., Stratta, G., Tanvir, N., Willingale, R., Attina, P., Campana, R., Castro-Tirado, A.J., Contini, C., Fuschino, F., Gomboc, A., Hudec, R., Orleanski, P., Renotte, E., Rodic, T., Bagoly, Z., Blain, A., Callanan, P., Covino, S., Ferrara, A., Le Floch, E., Marisaldi, M., Mereghetti, S., Rosati, P., Vacchi, A., D’Avanzo, P., Giommi, P., Piranomonte, S., Piro, L., Reglero, V., Rossi, A., Santangelo, A., Salvaterra, R., Tagliaferri, G., Vergani, S., Vinciguerra, S., Briggs, M., Campolongo, E., Ciolfi, R., Connaughton, V., Cordier, B., Morelli, B., Orlandini, M., Adami, C., Argan, A., Atteia, J.-L., Auricchio, N., Balazs, L., Baldazzi, G., Basa, S., Basak, R., Bellutti, P., Bernardini, M.G., Bertuccio, G., Braga, J., Branchesi, M., Brandt, S., Brocato, E., Budtz-Jorgensen, C., Bulgarelli, A., Burderi, L., Camp, J., Capozziello, S., Caruana, J., Casella, P., Cenko, B., Chardonnet, P., Ciardi, B., Colafrancesco, S., Dainotti, M.G., D’Elia, V., De Martino, D., De Pasquale, M., Del Monte, E., Della Valle, M., Drago, A., Evangelista, Y., Feroci, M., Finelli, F., Fiorini, M., Fynbo, J., Gal-Yam, A., Gendre, B., Ghisellini, G., Grado, A., Guidorzi, C., Hafizi, M., Hanlon, L., Hjorth, J., Izzo, L., Kiss, L., Kumar, P., Kuvvetli, I., Lavagna, M., Li, T., Longo, F., Lyutikov, M., Maio, U., Maiorano, E., Malcovati, P., Malesani, D., Margutti, R., Martin-Carrillo, A., Masetti, N., McBreen, S., Mignani, R., Morgante, G., Mundell, C., Nargaard-Nielsen, H.U., Nicastro, L., Palazzi, E., Paltani, S., Panessa, F., Pareschi, G., Pe’er, A., Penacchioni, A.V., Pian, E., Piedipalumbo, E., Piran, T., Rauw, G., Razzano, M., Read, A., Rezzolla, L., Romano, P., Ruffini, R., Savaglio, S., Sguera, V., Schady, P., Skidmore, W., Song, L., Stanway, E., Starling, R., Topinka, M., Troja, E., van Putten, M., Vanzella, E., Vercellone, S., Wilson-Hodge, C., Yonetoku, D., Zampa, G., Zampa, N., Zhang, B., Zhang, B.B., Zhang, S., Zhang, S.-N., Antonelli, A., Bianco, F., Boci, S., Boer, M., Botticella, M.T., Boulade, O., Butler, C., Campana, S., Capitanio, F., Celotti, A., Chen, Y., Colpi, M., Comastri, A., Cuby, J.-G., Dadina, M., De Luca, A., Dong, Y.-W., Ettori, S., Gandhi, P., Geza, E., Greiner, J., Guiriec, S., Harms, J., Hernanz, M., Hornstrup, A., Hutchinson, I., Israel, G., Jonker, P., Kaneko, Y., Kawai, N., Wiersema, K., Korpela, S., Lebrun, V., Lu, F., MacFadyen, A., Malaguti, G., Maraschi, L., Melandri, A., Modjaz, M., Morris, D., Omodei, N., Paizis, A., Páta, P., Petrosian, V., Rachevski, A., Rhoads, J., Ryde, F., Sabau-Graziati, L., Shigehiro, N., Sims, M., Soomin, J., Szécsi, D., Urata, Y., Uslenghi, M., Valenziano, L., Vianello, G., Vojtech, S., Watson, D., and Zicha, J.

Published
2018
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8. Fiber Driven Tilting Mechanism

Author

Svatoš, P., Šika, Z., Valášek, M., Zicha, J., Bauma, V., Rada, V., Dynybyl, Vojtěch, editor, Berka, Ondrej, editor, Petr, Karel, editor, Lopot, František, editor, and Dub, Martin, editor

Published
2016
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21. The THESEUS space mission concept: science case, design and expected performances

Author

Amati, L, O'Brien, P, Götz, D, Bozzo, E, Tenzer, C, Frontera, F, Ghirlanda, G, Labanti, C, Osborne, J, Stratta, G, Tanvir, N, Willingale, R, Attina, P, Campana, R, Castro-Tirado, A, Contini, C, Fuschino, F, Gomboc, A, Hudec, R, Orleanski, P, Renotte, E, Rodic, T, Bagoly, Z, Blain, A, Callanan, P, Covino, S, Ferrara, A, Le Floch, E, Marisaldi, M, Mereghetti, S, Rosati, P, Vacchi, A, D'Avanzo, P, Giommi, P, Piranomonte, S, Piro, L, Reglero, V, Rossi, A, Santangelo, A, Salvaterra, R, Tagliaferri, G, Vergani, S, Vinciguerra, S, Briggs, M, Campolongo, E, Ciolfi, R, Connaughton, V, Cordier, B, Morelli, B, Orlandini, M, Adami, C, Argan, A, Atteia, J, Auricchio, N, Balazs, L, Baldazzi, G, Basa, S, Basak, R, Bellutti, P, Bernardini, M, Bertuccio, G, Braga, J, Branchesi, M, Brandt, S, Brocato, E, Budtz-Jorgensen, C, Bulgarelli, A, Burderi, L, Camp, J, Capozziello, S, Caruana, J, Casella, P, Cenko, B, Chardonnet, P, Ciardi, B, Colafrancesco, S, Dainotti, M, D'Elia, V, De Martino, D, De Pasquale, M, Del Monte, E, Della Valle, M, Drago, A, Evangelista, Y, Feroci, M, Finelli, F, Fiorini, M, Fynbo, J, Gal-Yam, A, Gendre, B, Ghisellini, G, Grado, A, Guidorzi, C, Hafizi, M, Hanlon, L, Hjorth, J, Izzo, L, Kiss, L, Kumar, P, Kuvvetli, I, Lavagna, M, Li, T, Longo, F, Lyutikov, M, Maio, U, Maiorano, E, Malcovati, P, Malesani, D, Margutti, R, Martin-Carrillo, A, Masetti, N, Mcbreen, S, Mignani, R, Morgante, G, Mundell, C, Nargaard-Nielsen, H, Nicastro, L, Palazzi, E, Paltani, S, Panessa, F, Pareschi, G, Pe'Er, A, Penacchioni, A, Pian, E, Piedipalumbo, E, Piran, T, Rauw, G, Razzano, M, Read, A, Rezzolla, L, Romano, P, Ruffini, R, Savaglio, S, Sguera, V, Schady, P, Skidmore, W, Song, L, Stanway, E, Starling, R, Topinka, M, Troja, E, van Putten, M, Vanzella, E, Vercellone, S, Wilson-Hodge, C, Yonetoku, D, Zampa, G, Zampa, N, Zhang, B, Zhang, S, Antonelli, A, Bianco, F, Boci, S, Boer, M, Botticella, M, Boulade, O, Butler, C, Campana, S, Capitanio, F, Celotti, A, Chen, Y, Colpi, M, Comastri, A, Cuby, J, Dadina, M, De Luca, A, Dong, Y, Ettori, S, Gandhi, P, Geza, E, Greiner, J, Guiriec, S, Harms, J, Hernanz, M, Hornstrup, A, Hutchinson, I, Israel, G, Jonker, P, Kaneko, Y, Kawai, N, Wiersema, K, Korpela, S, Lebrun, V, Lu, F, Macfadyen, A, Malaguti, G, Maraschi, L, Melandri, A, Modjaz, M, Morris, D, Omodei, N, Paizis, A, Páta, P, Petrosian, V, Rachevski, A, Rhoads, J, Ryde, F, Sabau-Graziati, L, Shigehiro, N, Sims, M, Soomin, J, Szécsi, D, Urata, Y, Uslenghi, M, Valenziano, L, Vianello, G, Vojtech, S, Watson, D, Zicha, J, Amati, L., O'Brien, P., Götz, D., Bozzo, E., Tenzer, C., Frontera, F., Ghirlanda, G., Labanti, C., Osborne, J. P., Stratta, G., Tanvir, N., Willingale, R., Attina, P., Campana, R., Castro-Tirado, A. J., Contini, C., Fuschino, F., Gomboc, A., Hudec, R., Orleanski, P., Renotte, E., Rodic, T., Bagoly, Z., Blain, A., Callanan, P., Covino, S., Ferrara, A., Le Floch, E., Marisaldi, M., Mereghetti, S., Rosati, P., Vacchi, A., D'Avanzo, P., Giommi, P., Piranomonte, S., Piro, L., Reglero, V., Rossi, A., Santangelo, A., Salvaterra, R., Tagliaferri, G., Vergani, S., Vinciguerra, S., Briggs, M., Campolongo, E., Ciolfi, R., Connaughton, V., Cordier, B., Morelli, B., Orlandini, M., Adami, C., Argan, A., Atteia, J. -L., Auricchio, N., Balazs, L., Baldazzi, G., Basa, S., Basak, R., Bellutti, P., Bernardini, M. G., Bertuccio, G., Braga, J., Branchesi, M., Brandt, S., Brocato, E., Budtz-Jorgensen, C., Bulgarelli, A., Burderi, L., Camp, J., Capozziello, S., Caruana, J., Casella, P., Cenko, B., Chardonnet, P., Ciardi, B., Colafrancesco, S., Dainotti, M. G., D'Elia, V., De Martino, D., De Pasquale, M., Del Monte, E., Della Valle, M., Drago, A., Evangelista, Y., Feroci, M., Finelli, F., Fiorini, M., Fynbo, J., Gal-Yam, A., Gendre, B., Ghisellini, G., Grado, A., Guidorzi, C., Hafizi, M., Hanlon, L., Hjorth, J., Izzo, L., Kiss, L., Kumar, P., Kuvvetli, I., Lavagna, M., Li, T., Longo, F., Lyutikov, M., Maio, U., Maiorano, E., Malcovati, P., Malesani, D., Margutti, R., Martin-Carrillo, A., Masetti, N., McBreen, S., Mignani, R., Morgante, G., Mundell, C., Nargaard-Nielsen, H. U., Nicastro, L., Palazzi, E., Paltani, S., Panessa, F., Pareschi, G., Pe'er, A., Penacchioni, A. V., Pian, E., Piedipalumbo, E., Piran, T., Rauw, G., Razzano, M., Read, A., Rezzolla, L., Romano, P., Ruffini, R., Savaglio, S., Sguera, V., Schady, P., Skidmore, W., Song, L., Stanway, E., Starling, R., Topinka, M., Troja, E., van Putten, M., Vanzella, E., Vercellone, S., Wilson-Hodge, C., Yonetoku, D., Zampa, G., Zampa, N., Zhang, B., Zhang, B. B., Zhang, S., Zhang, S. -N., Antonelli, A., Bianco, F., Boci, S., Boer, M., Botticella, M. T., Boulade, O., Butler, C., Campana, S., Capitanio, F., Celotti, A., Chen, Y., Colpi, M., Comastri, A., Cuby, J. -G., Dadina, M., De Luca, A., Dong, Y. -W., Ettori, S., Gandhi, P., Geza, E., Greiner, J., Guiriec, S., Harms, J., Hernanz, M., Hornstrup, A., Hutchinson, I., Israel, G., Jonker, P., Kaneko, Y., Kawai, N., Wiersema, K., Korpela, S., Lebrun, V., Lu, F., MacFadyen, A., Malaguti, G., Maraschi, L., Melandri, A., Modjaz, M., Morris, D., Omodei, N., Paizis, A., Páta, P., Petrosian, V., Rachevski, A., Rhoads, J., Ryde, F., Sabau-Graziati, L., Shigehiro, N., Sims, M., Soomin, J., Szécsi, D., Urata, Y., Uslenghi, M., Valenziano, L., Vianello, G., Vojtech, S., Watson, D., Zicha, J., Amati, L, O'Brien, P, Götz, D, Bozzo, E, Tenzer, C, Frontera, F, Ghirlanda, G, Labanti, C, Osborne, J, Stratta, G, Tanvir, N, Willingale, R, Attina, P, Campana, R, Castro-Tirado, A, Contini, C, Fuschino, F, Gomboc, A, Hudec, R, Orleanski, P, Renotte, E, Rodic, T, Bagoly, Z, Blain, A, Callanan, P, Covino, S, Ferrara, A, Le Floch, E, Marisaldi, M, Mereghetti, S, Rosati, P, Vacchi, A, D'Avanzo, P, Giommi, P, Piranomonte, S, Piro, L, Reglero, V, Rossi, A, Santangelo, A, Salvaterra, R, Tagliaferri, G, Vergani, S, Vinciguerra, S, Briggs, M, Campolongo, E, Ciolfi, R, Connaughton, V, Cordier, B, Morelli, B, Orlandini, M, Adami, C, Argan, A, Atteia, J, Auricchio, N, Balazs, L, Baldazzi, G, Basa, S, Basak, R, Bellutti, P, Bernardini, M, Bertuccio, G, Braga, J, Branchesi, M, Brandt, S, Brocato, E, Budtz-Jorgensen, C, Bulgarelli, A, Burderi, L, Camp, J, Capozziello, S, Caruana, J, Casella, P, Cenko, B, Chardonnet, P, Ciardi, B, Colafrancesco, S, Dainotti, M, D'Elia, V, De Martino, D, De Pasquale, M, Del Monte, E, Della Valle, M, Drago, A, Evangelista, Y, Feroci, M, Finelli, F, Fiorini, M, Fynbo, J, Gal-Yam, A, Gendre, B, Ghisellini, G, Grado, A, Guidorzi, C, Hafizi, M, Hanlon, L, Hjorth, J, Izzo, L, Kiss, L, Kumar, P, Kuvvetli, I, Lavagna, M, Li, T, Longo, F, Lyutikov, M, Maio, U, Maiorano, E, Malcovati, P, Malesani, D, Margutti, R, Martin-Carrillo, A, Masetti, N, Mcbreen, S, Mignani, R, Morgante, G, Mundell, C, Nargaard-Nielsen, H, Nicastro, L, Palazzi, E, Paltani, S, Panessa, F, Pareschi, G, Pe'Er, A, Penacchioni, A, Pian, E, Piedipalumbo, E, Piran, T, Rauw, G, Razzano, M, Read, A, Rezzolla, L, Romano, P, Ruffini, R, Savaglio, S, Sguera, V, Schady, P, Skidmore, W, Song, L, Stanway, E, Starling, R, Topinka, M, Troja, E, van Putten, M, Vanzella, E, Vercellone, S, Wilson-Hodge, C, Yonetoku, D, Zampa, G, Zampa, N, Zhang, B, Zhang, S, Antonelli, A, Bianco, F, Boci, S, Boer, M, Botticella, M, Boulade, O, Butler, C, Campana, S, Capitanio, F, Celotti, A, Chen, Y, Colpi, M, Comastri, A, Cuby, J, Dadina, M, De Luca, A, Dong, Y, Ettori, S, Gandhi, P, Geza, E, Greiner, J, Guiriec, S, Harms, J, Hernanz, M, Hornstrup, A, Hutchinson, I, Israel, G, Jonker, P, Kaneko, Y, Kawai, N, Wiersema, K, Korpela, S, Lebrun, V, Lu, F, Macfadyen, A, Malaguti, G, Maraschi, L, Melandri, A, Modjaz, M, Morris, D, Omodei, N, Paizis, A, Páta, P, Petrosian, V, Rachevski, A, Rhoads, J, Ryde, F, Sabau-Graziati, L, Shigehiro, N, Sims, M, Soomin, J, Szécsi, D, Urata, Y, Uslenghi, M, Valenziano, L, Vianello, G, Vojtech, S, Watson, D, Zicha, J, Amati, L., O'Brien, P., Götz, D., Bozzo, E., Tenzer, C., Frontera, F., Ghirlanda, G., Labanti, C., Osborne, J. P., Stratta, G., Tanvir, N., Willingale, R., Attina, P., Campana, R., Castro-Tirado, A. J., Contini, C., Fuschino, F., Gomboc, A., Hudec, R., Orleanski, P., Renotte, E., Rodic, T., Bagoly, Z., Blain, A., Callanan, P., Covino, S., Ferrara, A., Le Floch, E., Marisaldi, M., Mereghetti, S., Rosati, P., Vacchi, A., D'Avanzo, P., Giommi, P., Piranomonte, S., Piro, L., Reglero, V., Rossi, A., Santangelo, A., Salvaterra, R., Tagliaferri, G., Vergani, S., Vinciguerra, S., Briggs, M., Campolongo, E., Ciolfi, R., Connaughton, V., Cordier, B., Morelli, B., Orlandini, M., Adami, C., Argan, A., Atteia, J. -L., Auricchio, N., Balazs, L., Baldazzi, G., Basa, S., Basak, R., Bellutti, P., Bernardini, M. G., Bertuccio, G., Braga, J., Branchesi, M., Brandt, S., Brocato, E., Budtz-Jorgensen, C., Bulgarelli, A., Burderi, L., Camp, J., Capozziello, S., Caruana, J., Casella, P., Cenko, B., Chardonnet, P., Ciardi, B., Colafrancesco, S., Dainotti, M. G., D'Elia, V., De Martino, D., De Pasquale, M., Del Monte, E., Della Valle, M., Drago, A., Evangelista, Y., Feroci, M., Finelli, F., Fiorini, M., Fynbo, J., Gal-Yam, A., Gendre, B., Ghisellini, G., Grado, A., Guidorzi, C., Hafizi, M., Hanlon, L., Hjorth, J., Izzo, L., Kiss, L., Kumar, P., Kuvvetli, I., Lavagna, M., Li, T., Longo, F., Lyutikov, M., Maio, U., Maiorano, E., Malcovati, P., Malesani, D., Margutti, R., Martin-Carrillo, A., Masetti, N., McBreen, S., Mignani, R., Morgante, G., Mundell, C., Nargaard-Nielsen, H. U., Nicastro, L., Palazzi, E., Paltani, S., Panessa, F., Pareschi, G., Pe'er, A., Penacchioni, A. V., Pian, E., Piedipalumbo, E., Piran, T., Rauw, G., Razzano, M., Read, A., Rezzolla, L., Romano, P., Ruffini, R., Savaglio, S., Sguera, V., Schady, P., Skidmore, W., Song, L., Stanway, E., Starling, R., Topinka, M., Troja, E., van Putten, M., Vanzella, E., Vercellone, S., Wilson-Hodge, C., Yonetoku, D., Zampa, G., Zampa, N., Zhang, B., Zhang, B. B., Zhang, S., Zhang, S. -N., Antonelli, A., Bianco, F., Boci, S., Boer, M., Botticella, M. T., Boulade, O., Butler, C., Campana, S., Capitanio, F., Celotti, A., Chen, Y., Colpi, M., Comastri, A., Cuby, J. -G., Dadina, M., De Luca, A., Dong, Y. -W., Ettori, S., Gandhi, P., Geza, E., Greiner, J., Guiriec, S., Harms, J., Hernanz, M., Hornstrup, A., Hutchinson, I., Israel, G., Jonker, P., Kaneko, Y., Kawai, N., Wiersema, K., Korpela, S., Lebrun, V., Lu, F., MacFadyen, A., Malaguti, G., Maraschi, L., Melandri, A., Modjaz, M., Morris, D., Omodei, N., Paizis, A., Páta, P., Petrosian, V., Rachevski, A., Rhoads, J., Ryde, F., Sabau-Graziati, L., Shigehiro, N., Sims, M., Soomin, J., Szécsi, D., Urata, Y., Uslenghi, M., Valenziano, L., Vianello, G., Vojtech, S., Watson, D., and Zicha, J.

Abstract

THESEUS is a space mission concept aimed at exploiting Gamma-Ray Bursts for investigating the early Universe and at providing a substantial advancement of multi-messenger and time-domain astrophysics. These goals will be achieved through a unique combination of instruments allowing GRB and X-ray transient detection over a broad field of view (more than 1sr) with 0.5–1 arcmin localization, an energy band extending from several MeV down to 0.3 keV and high sensitivity to transient sources in the soft X-ray domain, as well as on-board prompt (few minutes) follow-up with a 0.7 m class IR telescope with both imaging and spectroscopic capabilities. THESEUS will be perfectly suited for addressing the main open issues in cosmology such as, e.g., star formation rate and metallicity evolution of the inter-stellar and intra-galactic medium up to redshift ∼10, signatures of Pop III stars, sources and physics of re-ionization, and the faint end of the galaxy luminosity function. In addition, it will provide unprecedented capability to monitor the X-ray variable sky, thus detecting, localizing, and identifying the electromagnetic counterparts to sources of gravitational radiation, which may be routinely detected in the late ’20s/early ’30s by next generation facilities like aLIGO/ aVirgo, eLISA, KAGRA, and Einstein Telescope. THESEUS will also provide powerful synergies with the next generation of multi-wavelength observatories (e.g., LSST, ELT, SKA, CTA, ATHENA).

Published
2018

23. KLYPVE/TUS space experiments for study of ultrahigh-energy cosmic rays

Author

Khrenov, B. A., Alexandrov, V. V., Bugrov, D. I., Garipov, G. K., Kalmykov, N. N., Panasyuk, M. I., Sharakin, S. A., Silaev, A. A., Yashin, I. V., Grebenyuk, V. M., Naumov, D. V., Olshevsky, A. G., Sabirov, B. M., Semenov, R. N., Slunechka, M., Skryl, I. I., Tkatchev, L. G., Saprykin, O. A., Syromyatnikov, V. S., Bitkin, V. E., Eremin, S. A., Matyushkin, A. I., Urmantsev, F. F., Abrashin, V., Koval, V., Arakcheev, Y., Cordero, A., Martinez, O., Morena, E., Robledo, C., Salazar, H., Villasenor, L., Zepeda, A., Park, I., Shonsky, M., and Zicha, J.

Published
2004
Full Text
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38. The THESEUS space mission concept: science case, design and expected performances

Author

Agenzia Spaziale Italiana, European Commission, Czech Grant Agency, Amati, L., O'Brien, P., Götz, Diego, Bozz, Enrico, Tenzer, C., Frontera, F., Ghirlanda, G., Labanti, C., Osborne, Julian Paul, Stratta, G., Tanvir, N., Cenko, B., Marisaldi, M., Lavagna, M., Israel, G., Rhoads, J., Ryde, F., Basa, S., Sabau-Graziati, L., Capozziello, Salvatore, Kuvvetli, I., Korpela, S., Li, T., Maiorano, E., Renotte, E., Camp, J., Kumar, P., McBreen, S., Adami, C., Skidmore, W., Nargaard-Nielsen, H. U., Balazs, L., Topinka, M., Savaglio, S., Shigehiro, N., Sims, M., Soomin, J., Szécsi, D., Urata, Y., Evangelista, Y., Pasquale, Massimiliano de, Ciardi, B., Uslenghi, M., Willingale, R., Basak, R., Campana, R., Valenziano, L., D'Avanzo, P., Dainotti, M. G., Giommi, Paolo, Kiss, L., Romano, P., Schady, P., Martino, Domitilla de, Izzo, L., Capitanio, F., Starling, R., Drago, Alessandro, Comastri, Andrea, Boulade, O., Piranomonte, S., Piro, L., Reglero, V., Rossi, A., Santangelo, Andrea, Palazzi, E., Mundell, C., Masetti, N., Maio, U., Salvaterra, R., Ruffini, R., Finelli, F., Boci, S., Tagliaferri, G., Bellutti, P., Malcovati, P., Paltani, S., Bernardini, M. G., Rezzolla, L., Boer, M., Campana, Sergio, Margutti, R., Read, A., Maraschi, L., Colpi, Monica, Morgante, G., Omodei, Nicola, De Luca, A., Lebrun, V., Bertuccio, G., Braga, J., Branchesi, M., Brandt, S., Brocato, E., Troja, Eleonora, Stanway, E., Sguera, V., Budtz-Jørgensen, C., Panessa, F., Bulgarelli, A., Botticella, M.T., Nicastro, L., Kawai, N., Burderi, L., Fiorini, M., Fynbo, J., Putten, M. van, Gal-Yam, Avishay, Bianco, F., Kaneko, Y., Wiersema, K., MacFadyen, A., Martin-Carrillo, A., Antonelli, L. A., Hudec, René, Morris, D., Song, L., Callanan, P., Petrosian, V., Castro-Tirado, Alberto J., Zicha, J., Gendre, B., Ghisellini, G., Grado, A., Guidorzi, C., Hafizi, M., Dadina, M., Chen, Y., Butler, C., Hanlon, L., Vanzella, E., Longo, F., Hjorth, Jens, Attina, P., Fuschino, F., Pareschi, G., Jonker, P., Watson, D., Blain, A., Celotti, A., Orlandini, M., Floch, E. le, Cuby, Jean-Gabriel, Auricchio, N., Connaughton, Valerie, Pe'er, Asaf, Penacchioni, A. V., Pian, E., Piedipalumbo, E., Piran, T., Páta, P., Modjaz, M., Lu, F., Rauw, G., Rodic, T., Dong, Y. -W., Briggs, M., Razzano, M., Vercellone, S., Malaguti, G., Wilson-Hodge, C., Vojtech, S., Campolongo, E., Morelli, B., Melandri, A., Vianello, G., D'Elia, V., Atteia, J. L., Paizis, A., Della Valle, M., Chardonnet, P., Yonetoku, D., Zampa, G., Zampa, N., Zhang, B., Zhang, B. B., Mereghetti, S., Ferrara, Andrea, Bagoly, Z., Contini, C., Zhang, S., Ciolfi, Riccardo, Rachevski, A., Caruana, J., Zhang, Shuang-Nan, Ettori, S., Gomboc, A., Rosati, P., Gandhi, P., Vinciguerra, S., Casella, P., Colafrancesco, S., Orleanski, P., Vergani, S., Malesani, D., Monte, E. del, Covino, Stefano, Mignani, R., Feroci, Marco, Lyutikov, M., Geza, E., Greiner, Jochen, Guiriec, Sylvain, Harms, J., Hernanz, Margarita, Baldazzi, G., Argan, A., Cordier, B., Hornstrup, A., Vacchi, A., Hutchinson, I., Agenzia Spaziale Italiana, European Commission, Czech Grant Agency, Amati, L., O'Brien, P., Götz, Diego, Bozz, Enrico, Tenzer, C., Frontera, F., Ghirlanda, G., Labanti, C., Osborne, Julian Paul, Stratta, G., Tanvir, N., Cenko, B., Marisaldi, M., Lavagna, M., Israel, G., Rhoads, J., Ryde, F., Basa, S., Sabau-Graziati, L., Capozziello, Salvatore, Kuvvetli, I., Korpela, S., Li, T., Maiorano, E., Renotte, E., Camp, J., Kumar, P., McBreen, S., Adami, C., Skidmore, W., Nargaard-Nielsen, H. U., Balazs, L., Topinka, M., Savaglio, S., Shigehiro, N., Sims, M., Soomin, J., Szécsi, D., Urata, Y., Evangelista, Y., Pasquale, Massimiliano de, Ciardi, B., Uslenghi, M., Willingale, R., Basak, R., Campana, R., Valenziano, L., D'Avanzo, P., Dainotti, M. G., Giommi, Paolo, Kiss, L., Romano, P., Schady, P., Martino, Domitilla de, Izzo, L., Capitanio, F., Starling, R., Drago, Alessandro, Comastri, Andrea, Boulade, O., Piranomonte, S., Piro, L., Reglero, V., Rossi, A., Santangelo, Andrea, Palazzi, E., Mundell, C., Masetti, N., Maio, U., Salvaterra, R., Ruffini, R., Finelli, F., Boci, S., Tagliaferri, G., Bellutti, P., Malcovati, P., Paltani, S., Bernardini, M. G., Rezzolla, L., Boer, M., Campana, Sergio, Margutti, R., Read, A., Maraschi, L., Colpi, Monica, Morgante, G., Omodei, Nicola, De Luca, A., Lebrun, V., Bertuccio, G., Braga, J., Branchesi, M., Brandt, S., Brocato, E., Troja, Eleonora, Stanway, E., Sguera, V., Budtz-Jørgensen, C., Panessa, F., Bulgarelli, A., Botticella, M.T., Nicastro, L., Kawai, N., Burderi, L., Fiorini, M., Fynbo, J., Putten, M. van, Gal-Yam, Avishay, Bianco, F., Kaneko, Y., Wiersema, K., MacFadyen, A., Martin-Carrillo, A., Antonelli, L. A., Hudec, René, Morris, D., Song, L., Callanan, P., Petrosian, V., Castro-Tirado, Alberto J., Zicha, J., Gendre, B., Ghisellini, G., Grado, A., Guidorzi, C., Hafizi, M., Dadina, M., Chen, Y., Butler, C., Hanlon, L., Vanzella, E., Longo, F., Hjorth, Jens, Attina, P., Fuschino, F., Pareschi, G., Jonker, P., Watson, D., Blain, A., Celotti, A., Orlandini, M., Floch, E. le, Cuby, Jean-Gabriel, Auricchio, N., Connaughton, Valerie, Pe'er, Asaf, Penacchioni, A. V., Pian, E., Piedipalumbo, E., Piran, T., Páta, P., Modjaz, M., Lu, F., Rauw, G., Rodic, T., Dong, Y. -W., Briggs, M., Razzano, M., Vercellone, S., Malaguti, G., Wilson-Hodge, C., Vojtech, S., Campolongo, E., Morelli, B., Melandri, A., Vianello, G., D'Elia, V., Atteia, J. L., Paizis, A., Della Valle, M., Chardonnet, P., Yonetoku, D., Zampa, G., Zampa, N., Zhang, B., Zhang, B. B., Mereghetti, S., Ferrara, Andrea, Bagoly, Z., Contini, C., Zhang, S., Ciolfi, Riccardo, Rachevski, A., Caruana, J., Zhang, Shuang-Nan, Ettori, S., Gomboc, A., Rosati, P., Gandhi, P., Vinciguerra, S., Casella, P., Colafrancesco, S., Orleanski, P., Vergani, S., Malesani, D., Monte, E. del, Covino, Stefano, Mignani, R., Feroci, Marco, Lyutikov, M., Geza, E., Greiner, Jochen, Guiriec, Sylvain, Harms, J., Hernanz, Margarita, Baldazzi, G., Argan, A., Cordier, B., Hornstrup, A., Vacchi, A., and Hutchinson, I.

Abstract

THESEUS is a space mission concept aimed at exploiting Gamma-Ray Bursts for investigating the early Universe and at providing a substantial advancement of multi-messenger and time-domain astrophysics. These goals will be achieved through a unique combination of instruments allowing GRB and X-ray transient detection over a broad field of view (more than 1sr) with 0.5¿1 arcmin localization, an energy band extending from several MeV down to 0.3¿keV and high sensitivity to transient sources in the soft X-ray domain, as well as on-board prompt (few minutes) follow-up with a 0.7¿m class IR telescope with both imaging and spectroscopic capabilities. THESEUS will be perfectly suited for addressing the main open issues in cosmology such as, e.g., star formation rate and metallicity evolution of the inter-stellar and intra-galactic medium up to redshift 10, signatures of Pop III stars, sources and physics of re-ionization, and the faint end of the galaxy luminosity function. In addition, it will provide unprecedented capability to monitor the X-ray variable sky, thus detecting, localizing, and identifying the electromagnetic counterparts to sources of gravitational radiation, which may be routinely detected in the late ¿20s/early ¿30s by next generation facilities like aLIGO/ aVirgo, eLISA, KAGRA, and Einstein Telescope. THESEUS will also provide powerful synergies with the next generation of multi-wavelength observatories (e.g., LSST, ELT, SKA, CTA, ATHENA).© 2018 COSPAR

Published
2018

44. Polymorphism in Nos2 gene is absent in Prague colony of Dahl/Rapp salt-sensitive and salt-resistant rats

Author

Hojná S, Kadlecová M, Zicha J, and Jaroslav Kunes

Subjects
Male, Polymorphism, Genetic, Rats, Inbred Dahl, Physiology, Animals, Nitric Oxide Synthase Type II, Blood Pressure, General Medicine, Czech Republic, Rats
Abstract

We have searched for polymorphism of inducible nitric oxide synthase gene (Nos2 gene) in the Prague colony of salt-sensitive and salt-resistant Dahl/Rapp rats. Specific primers were used to confirm previously described Nos2 gene polymorphism because this gene was suggested to be a potential candidate gene for genetic hypertension. Phenotyping (blood pressure, organ weight, plasma lipids) have confirmed the data known from other colonies of Dahl/Rapp rats. However, in our colony we were not able to find any Nos2 gene polymorphism between salt-sensitive and salt-resistant rats, which was previously described in animals from Harlan colony. Moreover, the genetic homogeneity of our salt-sensitive and salt-resistant rats in terms of Nos2 gene was the same as in the original Brookhaven colony of Dahl rats. This is surprising because our colony has been established from breeding pairs kindly provided by Prof. J.P. Rapp more than 15 years ago. It seems that the polymorphism found in Harlan colony could be the result of previous contamination or genetic drift during the breeding conditions specific for this colony.

Published
2005
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45. Altered balance of vasoactive systems in experimental hypertension: the role of relative NO deficiency

Author

Kunes, J., Hojna, S., Kadlecova, M., Dobesova, Z., Rauchova, H., Martina Vokurkova, Loukotova, J., Pechanova, O., and Zicha, J.

Subjects
Male, Rats, Inbred Dahl, Physiology, Age Factors, General Medicine, Nitric Oxide, Muscle, Smooth, Vascular, Rats, NG-Nitroarginine Methyl Ester, Sex Factors, Rats, Inbred SHR, Hypertension, Animals, Calcium, Female, Salts, Calcium Channels, Reactive Oxygen Species
Abstract

This review summarizes our findings concerning the altered balance of vasoactive systems (namely sympathetic nervous system and nitric oxide) in various forms of experimental hypertension--genetic hypertension (SHR, HTG rats), salt hypertension (Dahl rats) and NO-deficient hypertension (L-NAME-treated rats). An attempt is made to define relative NO deficiency (compared to the existing level of sympathetic vasoconstriction), to describe its possible causes and to evaluate particular indicators of its extent. A special attention is paid to reactive oxygen species, their interaction with NO metabolism, cell Ca2+ handling and blood pressure regulation. Our current effort is focused on the investigation of abnormal regulation of cytosolic Ca2+ levels in smooth muscle and endothelium of hypertensive animals. Such a research should clarify the mechanisms by which genetic and/or environmental factors could chronically modify blood pressure level.

Published
2004
Full Text
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46. Results and Perspectives for Laboratory Search of Weakly Interacting Sub-eV Particles with the OSQAR Experiment

Author

Pugnat, P., Ballou, R., Schott, M., Husek, T., Sulc, M., Deferne, G., Duvillaret, L., Finger, M., Flekova, L., Hosek, J., Jary, V., Jost, R., Kral, M., Kunc, S., Macuchova, K., Meissner, K. A., Morville, J., Romanini, D., Siemko, A., Slunecka, M., Vitrant, G., Zicha, J., Magnétisme et Supraconductivité (MagSup), Institut Néel (NEEL), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Kapteos SAS, LAsers, Molécules et Environnement (LAME-LIPhy), Laboratoire Interdisciplinaire de Physique [Saint Martin d’Hères] (LIPhy), Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Technical University of Liberec, University of Liberec, Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Institut de Microélectronique, Electromagnétisme et Photonique - Laboratoire d'Hyperfréquences et Caractérisation (IMEP-LAHC), and Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National Polytechnique de Grenoble (INPG)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)

Subjects
Experiment, [PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics], Phenomenology, Cosmology and Extragalactic Astrophysics, High Energy Physics, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Astrophysics
Abstract

Recent intensive theoretical and experimental studies highlight the possibility of new fundamental particle physics beyond the standard model that can be probed by sub-eV energy experiments. The OSQAR photon regeneration experiment looks for Light Shining through a Wall (LSW) from the quantum oscillation of optical photons into Weakly Interacting Sub-eV Particles (WISPs), like axion or axion-like particles (ALPs), in a 9 T transverse magnetic field over the unprecedented length of 2 x 14.3 m. No excess of events has been detected over the background. The di-photon couplings of possible new light scalar and pseudo-scalar particles can be constrained in the massless limit to be less than 8.0 x 10-8 GeV-1. These results are very close to the most stringent laboratory constraints obtained for the coupling of WISPs to two photons. Plans for further improving the sensitivity of the OSQAR experiment are presented.

Published
2014

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