410 results on '"Ziegler, Slava"'
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2. Morphological subprofile analysis for bioactivity annotation of small molecules
3. Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds
4. Tafbromin selectively targets the TAF1 bromodomain
5. Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis
6. Discovery of a σ1 receptor antagonist by combination of unbiased cell painting and thermal proteome profiling
7. Morphological profiling of small molecules
8. Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay.
9. The Pseudo‐Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2.
10. Illuminating Dark Chemical Matter Using the Cell Painting Assay
11. Discovery of a Novel Pseudo‐Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling
12. Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator
13. Discovery of a novel pseudo-natural product Aurora kinase inhibitor chemotype through morphological profiling
14. Discovery of the sEH Inhibitor Epoxykynin as Potent Kynurenine Pathway Modulator
15. Detection of a Mitochondrial Stress Phenotype using the Cell Painting Assay
16. Inducin Triggers LC3‐Lipidation and ESCRT‐Mediated Lysosomal Membrane Repair
17. Identification of cytotoxic, glutathione-reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion
18. Identification of novel PDEδ interacting proteins
19. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis
20. Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space
21. Chromopynones are pseudo natural product glucose uptake inhibitors targeting glucose transporters GLUT-1 and -3
22. Kooperative Lewis‐Säure‐1,2,3‐Triazolium‐Aryloxid‐Katalyse: Addition von Pyrazolonen an Nitroolefine als Zugang zu Diaminoamiden
23. Cooperative Lewis Acid‐1,2,3‐Triazolium‐Aryloxide Catalysis: Pyrazolone Addition to Nitroolefins as Entry to Diaminoamides
24. Illuminating Dark Chemical Matter using the Cell Painting Assay
25. Novel approaches to map small molecule–target interactions
26. A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics
27. Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs
28. Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells?
29. Inducin triggers LC3-lipidation and ESCRT-mediated lysosomal membrane repair
30. Morphological profiling identifies the motor protein Eg5 as cellular target of spirooxindoles
31. Hunting the Targets of Natural Product-Inspired Compounds
32. The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation
33. Podoverine A—a novel microtubule destabilizing natural product from the Podophyllum species
34. Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone
35. Identification of Dihydroorotate Dehydrogenase Inhibitors Using the Cell Painting Assay
36. Identification of a Novel Pseudo‐Natural Product Type IV IDO1 Inhibitor Chemotype
37. Morphological Subprofile Analysis for Bioactivity Annotation of Small Molecules
38. The Pseudo‐Natural Product Rhonin Targets RHOGDI
39. Nutrient-Based Chemical Library as a Source of Energy Metabolism Modulators
40. Chronological expression of Wnt target genes Ccnd1, Myc, Cdkn1a, Tfrc, Plf1 and Ramp3
41. Identification of the Targets of Biologically Active Small Molecules Using Quantitative Proteomics
42. Identification of the Targets of Natural-Product-Inspired Mitotic Inhibitors
43. Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products
44. Lipocalin 24p3 is regulated by the Wnt pathway independent of regulation by iron
45. Cell‐Based Identification of New IDO1 Modulator Chemotypes
46. Hunting the Targets of Natural Product-Inspired Compounds
47. Discovery of small-molecule modulator of heterotrimeric Gi-protein by integrated phenotypic profiling and chemical proteomics
48. Cover Feature: Morphological Profiling Identifies a Common Mode of Action for Small Molecules with Different Targets (ChemBioChem 22/2020)
49. Morphological Profiling Identifies a Common Mode of Action for Small Molecules with Different Targets
50. Correction to “Nutrient-Based Chemical Library as a Source of Energy Metabolism Modulators”
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