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2. Comments on “Preventive home therapy for symptomatic patients affected by COVID-19 and followed by teleconsultations” by D'Amato et al

Author

Adiletta, G, Baglioni, S, Bettoncelli, G, Bracciale, P, Cazzola, M, Clini, E, Cutrera, R, D'Adduzio, F, de Blasio, F, Ferraro, F, Fumagalli, R, Lequaglie, C, Matera, M, Numis, F, Palange, P, Picciolo, S, Potena, A, Romano, F, Sabato, E, Sacchetta, A, Spatafora, M, Stefanelli, F, Zottola, C, Adiletta G., Baglioni S., Bettoncelli G., Bracciale P., Cazzola M., Clini E. M., Cutrera R., D'Adduzio F., de Blasio F., Ferraro F., Fumagalli R., Lequaglie C., Matera M. G., Numis F., Palange P., Picciolo S., Potena A., Romano F., Sabato E., Sacchetta A., Spatafora M., Stefanelli F., Zottola C., Adiletta, G, Baglioni, S, Bettoncelli, G, Bracciale, P, Cazzola, M, Clini, E, Cutrera, R, D'Adduzio, F, de Blasio, F, Ferraro, F, Fumagalli, R, Lequaglie, C, Matera, M, Numis, F, Palange, P, Picciolo, S, Potena, A, Romano, F, Sabato, E, Sacchetta, A, Spatafora, M, Stefanelli, F, Zottola, C, Adiletta G., Baglioni S., Bettoncelli G., Bracciale P., Cazzola M., Clini E. M., Cutrera R., D'Adduzio F., de Blasio F., Ferraro F., Fumagalli R., Lequaglie C., Matera M. G., Numis F., Palange P., Picciolo S., Potena A., Romano F., Sabato E., Sacchetta A., Spatafora M., Stefanelli F., and Zottola C.

Published
2021

3. Paroxetine and fluoxetine effects on mood and cognitive functions in depressed nondemented elderly patients

Author

Cassano G, B, Puca F, Scapicchio P, L, Trabucchi M, Aguglia E, Albano C, Bruzzone G, Antico L, Guidi L, Tricerfi A, Cappa C, Smerieri G, Simonini E, Tilli C, Caserta F, Varia S, Cerqua R, Califano M, Cerqua G, Chioma V, Bertuzzi D, Menetti M, Corsonello F, Zottola C, Pranno L, De Candia R, Di Fiorino M, Cerfi A, Bani A, Fichera G, Bonomol G, Giberti G, Cassis S, Grumelli B, Galetti G, Anni G, Guala A, Lancia U, Saponaro A, Longobardi L, Bruni A, Macchione C, Fantò F, Baietto T, Martucci M, Faronl J, Calandriello L, Meduri M, Di Rosa A, E, Cacciola M, Mordechai M, Zuccaro S, M, Palummeri E, Cella A, Trasciatti S, Paolucci S, Coiro R, Pedone V, Angelini A, Piani F, Righini D, Puca E, Brancasi B, Rengo F, Cacciatore F, Robotti C, A, Bilone F, Nicotra M, C, Rotolo V, Salsi A, De Carolis S, Scarpino O, Del Gobbo M, Sdanganelli F, Di Biase A, Pontrelli B, Spilimbergo P, G, Di Costanzo E, Matranga M, Stocchi E, Grassini P, Valenti G, Fontana V, Venuta M, Guaraldi G, P, Zanni L, Verrienti P, Stoppelli N, Scardino V, Vischia F, Pirfo E., ABETE, PASQUALE, Cassano, G, B, Puca, F, Scapicchio, P, L, Trabucchi, M, Aguglia, E, Albano, C, Bruzzone, G, Antico, L, Guidi, L, Tricerfi, A, Cappa, C, Smerieri, G, Simonini, E, Tilli, C, Caserta, F, Varia, S, Cerqua, R, Califano, M, Cerqua, G, Chioma, V, Bertuzzi, D, Menetti, M, Corsonello, F, Zottola, C, Pranno, L, De Candia, R, Di Fiorino, M, Cerfi, A, Bani, A, Fichera, G, Bonomol, G, Giberti, G, Cassis, S, Grumelli, B, Galetti, G, Anni, G, Guala, A, Lancia, U, Saponaro, A, Longobardi, L, Bruni, A, Macchione, C, Fantò, F, Baietto, T, Martucci, M, Faronl, J, Calandriello, L, Meduri, M, Di Rosa, A, E, Cacciola, M, Mordechai, M, Zuccaro, S, M, Palummeri, E, Cella, A, Trasciatti, S, Paolucci, S, Coiro, R, Pedone, V, Angelini, A, Piani, F, Righini, D, Puca, E, Brancasi, B, Rengo, F, Abete, Pasquale, Cacciatore, F, Robotti, C, A, Bilone, F, Nicotra, M, Rotolo, V, Salsi, A, De Carolis, S, Scarpino, O, Del Gobbo, M, Sdanganelli, F, Di Biase, A, Pontrelli, B, Spilimbergo, P, G, Di Costanzo, E, Matranga, M, Stocchi, E, Grassini, P, Valenti, G, Fontana, V, Venuta, M, Guaraldi, G, P, Zanni, L, Verrienti, P, Stoppelli, N, Scardino, V, Vischia, F, and Pirfo, E.

Published
2002

4. Paroxetine and fluoxetine effects on mood and cognitive functions in depressed nondemented elderly patients

Author

Cassano, Gb, Puca, F, Scapicchio, Pl, Trabucchi, M, Aguglia, Eugenio, Albano, C, Bruzzone, G, Antico, L, Giudi, L, Tricerfi, A, Cappa, C, Smerieri, G, Gassano, Gb, Sinonimi, E, Tilli, C, Caserta, F, Varia, S, Serqua, R, Califfato, M, Serqua, G, Chioma, V, Bertuzzi, D, Menetti, M, Corsonello, F, Zottola, C, Prano, L, De Candia, R, Di Giberti, G, Cassisi, S, Grumelli, B, Galletti, G, Anni, G, Guala, A, Lancia, U, Saponaro, A, Longobardi, L, Bruni, A, Fichera, G, Bonomol, G, and Giberti, G.

Published
2002

8. Paroxetine and fluoxetine effects on mood and cognitive functions in depressed nondemented elderly patients

Author

Cassano, G. B., Puca, F., Scapicchio, P. L., Trabucchi, M., Aguglia, E., Albano, C., Bruzzone, G., Antico, L., Guidi, L., Tricerfi, A., Cappa, C., Smerieri, G., Simonini, E., Tilli, C., Caserta, F., Varia, S., Cerqua, R., Califano, M., Cerqua, G., Chioma, V., Bertuzzi, D., Menetti, M., Corsonello, F., Zottola, C., Pranno, L., Candia, R., Di Fiorino, M., Cerfi, A., Bani, A., Fichera, G., Bonomol, G., Giberti, G., Cassis, S., Grumelli, B., Galetti, G., Anni, G., Guala, A., Lancia, U., Saponaro, A., Longobardi, L., Bruni, A., Macchione, C., Fantò, F., Baietto, T., Martucci, M., Faronl, J., Calandriello, L., Meduri, M., Di Rosa, A. E., Cacciola, M., Mordechai, M., Zuccaro, S. M., Palummeri, E., Cella, A., Trasciatti, S., Paolucci, S., Coiro, R., Pedone, V., Angelini, A., Piani, F., Righini, D., Puca, E., Brancasi, B., Rengo, F., Pasquale ABETE, Cacciatore, F., Robotti, C. A., Bilone F., Nicotra, M. C., Rotolo, V., Salsi, A., Carolis, S., Scarpino, O., Del Gobbo, M., Sdanganelli, F., Di Biase, A., Pontrelli, B., Spilimbergo, P. G., Di Costanzo, E., Matranga, M., Stocchi, E., Grassini, P., Valenti, G., Fontana, V., Venuta, M., Guaraldi, G. P., Zanni, L., Verrienti, P., Stoppelli, N., Scardino, V., Vischia, F., and Pirfo, E.

16. Comments on 'Preventive home therapy for symptomatic patients affected by COVID-19 and followed by teleconsultations' by D'Amato et al

Author

Francesco De Blasio, Fabio Numis, Antonio Sacchetta, Francesco Stefanelli, Mario Spatafora, Franco D'Adduzio, Stefano Baglioni, Fausto Ferraro, Potena A, Mario Cazzola, Stefano Picciolo, Carlo Zottola, Francesco Romano, Cosimo Lequaglie, Roberto Fumagalli, Renato Cutrera, Pierluigi Bracciale, Enrico Clini, Germano Bettoncelli, Eugenio Sabato, Paolo Palange, Girolamo Adiletta, Maria Gabriella Matera, Adiletta, G., Baglioni, S., Bettoncelli, G., Bracciale, P., Cazzola, M., Clini, E. M., Cutrera, R., D'Adduzio, F., de Blasio, F., Ferraro, F., Fumagalli, R., Lequaglie, C., Matera, M. G., Numis, F., Palange, P., Picciolo, S., Potena, A., Romano, F., Sabato, E., Sacchetta, A., Spatafora, M., Stefanelli, F., and Zottola, C.

Subjects
Pulmonary and Respiratory Medicine, Pediatrics, medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), business.industry, Home therapy, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19, 030204 cardiovascular system & hematology, LMWH, 03 medical and health sciences, 0302 clinical medicine, medicine, Steroids, business, Letter to the Editor, 030215 immunology
Abstract

We have read with interest the letter from D’Amato et al. entitled “Preventive home therapy for symptomatic patients affected by COVID-19 and followed by teleconsultations”....

Published
2021

17. Chorioamnionitis after premature rupture of membranes in nulliparas undergoing labor induction: prostaglandin E2 vs. oxytocin.

Author

Gulersen M, Zottola C, Li X, Krantz D, DiSturco M, and Bornstein E

Subjects
Adult, Female, Humans, Infant, Newborn, Outcome and Process Assessment, Health Care, Oxytocics administration & dosage, Oxytocics adverse effects, Pregnancy, Pregnancy Outcome epidemiology, Prognosis, Retrospective Studies, Risk Assessment methods, United States epidemiology, Cervical Ripening drug effects, Chorioamnionitis diagnosis, Chorioamnionitis epidemiology, Chorioamnionitis etiology, Chorioamnionitis prevention & control, Dinoprostone administration & dosage, Dinoprostone adverse effects, Fetal Membranes, Premature Rupture diagnosis, Fetal Membranes, Premature Rupture etiology, Labor, Induced adverse effects, Labor, Induced methods, Labor, Induced statistics & numerical data, Oxytocin administration & dosage, Oxytocin adverse effects
Abstract

Objectives: To assess the risk of chorioamnionitis in nulliparous, term, singleton, vertex (NTSV) pregnancies with premature rupture of membranes (PROM) and an unfavorable cervix undergoing labor induction with either prostaglandin E2 (PGE2) or oxytocin only., Methods: Retrospective cohort of NTSV pregnancies presenting with PROM who underwent labor induction with either PGE2 (n=94) or oxytocin (n=181) between October 2015 and March 2019. The primary outcome of chorioamnionitis was compared between the two groups. Statistical analysis included Chi-squared and Wilcoxon rank-sum tests, as well as logistic regression. For time to delivery, a Cox proportional hazard regression was used to determine the hazard ratio (HR) and adjusted HR (aHR)., Results: Baseline characteristics were similar between the two groups. Cervical ripening with PGE2 was associated with an increased rate of chorioamnionitis (18.1 vs. 6.1%; aOR 4.14, p=0.001), increased neonatal intensive care unit admissions (20.2 vs. 9.9%; aOR 2.4, p=0.02), longer time interval from PROM to delivery (24.4 vs. 17.9 h; aHR 0.56, p=<0.0001), and lower incidence of meconium (7.4 vs. 14.4%; aOR 0.26, p=0.01), compared to the oxytocin group., Conclusions: Based on our data, the use of oxytocin appears both superior and safer compared to PGE2 in NTSV pregnancies with PROM undergoing labor induction., (© 2021 Walter de Gruyter GmbH, Berlin/Boston.)

Published
2021
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19. Implementation of a Standardized Post-Cesarean Delivery Order Set with Multimodal Combination Analgesia Reduces Inpatient Opioid Usage.

Author

Bornstein E, Husk G, Lenchner E, Grunebaum A, Gadomski T, Zottola C, Werner S, Hirsch JS, and Chervenak FA

Abstract

Background: Opioid use has emerged as a leading cause of death in the US. Given that 1 in 300 opioid-naive patients exposed to opioids after cesarean birth will become persistent users, hospitals should strive to limit exposure to these medications. We set out to evaluate whether transitioning to a standardized order set based on multimodal combination analgesic therapy decreases the exposure to opioids after cesarean delivery. Methods: Our health system's post-cesarean pain management electronic medical record (EMR) order set was changed from standing NSAIDs (Ibuprofen 600 mg every 6 h) and additional acetaminophen and opioid medications (Oxycodone 5 mg/acetaminophen 325 mg every 3 h or Oxycodone 10 mg/acetaminophen 650 mg every 6 h for moderate and severe pain, respectively) as needed (PRN) to a multimodal combination therapy with acetaminophen (975 mg every 6 h) and NSAIDs (Ibuprofen 600 mg every 6 h) as primary analgesics and opioids PRN (Oxycodone immediate release (IR) 5 mg every 3 h for moderate to severe pain). We performed a retrospective analysis across seven hospitals comparing inpatient opioid use, administration of other analgesics, and severe pain episodes (pain score ≥ 7) between the patients who were treated before and after implementation of the multimodal order set. Chi square and Student t-test were used for statistical analysis with significance determined as p < 0.05. Results: A total of 12,898 cesarean births were included (8696 prior and 4202 after implementation). The multimodal order set was associated with marked decrease in the incidence of post cesarean opioid use (45.4% vs. 67.5%; p < 0.0001), lower average opioid dose (26.7 mg vs. 36.6 mg of oxycodone; p < 0.0001), and increased dose of acetaminophen (8422 mg vs. 4563 mg; p < 0.0001), while severe pain scores were less frequent (46.3% vs. 56.6%, p < 0.0001). Conclusions: Multimodal analgesic therapy for post-cesarean pain management reduces inpatient opioid use while improving pain control. Incorporation of a multimodal order set as a default in the EMR facilitates effective and widespread implementation on a large scale. Obstetric units should consider standardizing post-cesarean pain management orders to include routine (not PRN) multimodal combination therapy with acetaminophen and NSAIDs as primary analgesics., Competing Interests: The authors declare no conflict of interest.

Published
2020
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20. Ovarian teratoma with pituitary tissue: A case report.

Author

Werner S, Zottola C, Steinberg J, Pearson B, and Katz A

Abstract

Ovarian cysts and specifically ovarian teratomas are a common finding in young patients. These cysts display histological cell types from all three cells lines: endodermal, ectodermal and mesodermal origins. A 22-year-old woman who displayed classic signs of cortisol excess - excessive weight gain, difficultly losing weight and abdominal striae - was found to have a 10 cm mature teratoma cyst. This patient presented with ovarian torsion, a common complication of ovarian cysts, and was treated surgically. Pathology was significant for an ovarian teratoma with pituitary secreting cells, most significantly cells secreting adrenocorticotropic hormone (ACTH)., (© 2020 The Authors.)

Published
2020
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