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BackgroundCervical cancer is the secondmost common malignancy in women worldwide.The vast majority of cervical cancersare associatedwith high risk HPV16 infection. The persistence of HPV16 and integration of viral DNA into cell genome are necessary for thedevelopment of precancerous lesion and squamous cell carcinoma (SCC) of the cervix. The integration of viral DNA in the host cellgenome resulted in the regulation of oncoprotein E7 leading to detection of HPV16 E7 expression in precancerous lesions and SCCof the cervix.The aim of this study was to evaluate differences of HPV16 E7 expression in precancerous lesions and cervical SCC.MethodsAn observational study with cross-sectional design was performedat Department of Anatomical Pathology Faculty of MedicineUniversity of Sriwijaya/dr. Mohammad Hoesin General Hospital Palembang, from 1st July 2014 to 30st Juni 2017. The selectedsamples consisted of 25 precancerous cases lesions (13 cases of LSIL and 12 samples of HSIL) and SCC (25 cases).Immuhistochemical stained was conducted using HPV16 E7 antibody. Fisher exact’s test was used to analyze differences inexpression of HPV16 E7 among precancerous lesions and cervical SCC.ResultsThe pracancerous lesions occurred mostly between the ages of 30-40 years, while SCC were those between the ages of 51-60years. All SCC cases (100%) and 91.6% of HSIL showed weak to strong HPV16 E7 expression, and 84.6% cases of LSIL showedimmunonegative.ConclusionThe positivity of HPV16 E7 increased in HSIL and KSS lesions.

Melanoma maligna merupakan tumor ganas yang berasal dari melanosit dengan gambaran berupa lesi kehitam-hitaman pada kulit. Melanoma maligna merupakan satu dari tiga jenis kanker kulit yang mempunyai insiden terendah namun angka kematian yang disebabkannya cenderung lebih besar yaitu 75% akibat kanker kulit. Penelitian ini bertujuan untuk mengetahui karakteristik histopatologi melanoma maligna pada sediaan di Bagian Patologi Anatomi RSUP Dr. Mohammad Hoesin Palembang pada tahun 2009-2013. Jenis penelitian yang digunakan adalah metode deskriptif observasional dengan pendekatan cross sectional. Dari 29.175 rekam medik pasien di Bagian Patologi Anatomi RSMH selama 2009-2013, diperoleh 30 kasus melanoma maligna yang memenuhi kriteria inklusi. Angka kejadian melanoma maligna di Bagian Patologi Anatomi RSUP Dr. Mohammad Hoesin Palembang tahun 2009-2013 adalah 0.103%. Melanoma maligna lebih banyak ditemukan pada perempuan (70%) daripada laki-laki (30%), dan paling sering terjadi pada kelompok usia 45-53 tahun dengan persentase 30%. Karakteristik histopatologi yang paling banyak ditemukan dalam penelitian ini adalah subtipe nodular melanoma (100%). Angka kejadian melanoma maligna di Bagian Patologi Anatomi RSMH tahun 2009-2013 adalah 0,103%, dengan angka kejadian tertinggi pada tahun 2012 yaitu 0.28%. Nodular melanoma merupakan subtipe yang paling banyak ditemukan.

Hepatoblastoma merupakan tumor ganas hati mengandung komponen epitelial dan mesenkimal, paling sering terjadi pada usia

The study aims to analyze the adequacy of water in the area Tonsewer for the growth of tomato plants and corn. This research conducted in Tonsewer village, West Tompaso. Materials and equipment use are drill, ring sampels, hoes, sholves, machetes, laboratory equipment, sack,plastic, rubber, 10 years of climate data (monthly rainfall, humidity, watering time,wind speed, maximum and minimum temperatures), soil data, and plants data.The result using the model of CropWat8 that condition the availability of water for crops as tomatoes and corn sufficient available. Planting June 1st decreased soil moisture ahead of the third phase of growth of tomato plants.Tomato plants need sufficient water in the initiation phase/transplanting and in the initial phase until the final disposal phase of fruitformation. Planting time June 1st and July 1st the reduction soil moisture at planting time these two accurred in the third growth phase reach a position under conditions readily available in the fourth growth phase.Keywords : water availability, evapotranspiration, CropWat8 model