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The present study was conducted on broiler chickens ( at day 21 age ) which were infected by oral administration with Eimeria tenella oocyst suspension containing (1 × 10 5) oocyst / chick . Broiler chickens were divided Randomly into nine groups (10 chickens per each group) and were watched during the first and second weeks after infection The results revealed that the infected chickens clinically showed dullness and Anorexia . Microscopically , There were haemorrhagic inflammation , haemorrhagic spots on the intestine and in addition to congestion and enlargement of the caecal tonsils . The study was also included the supplementation of broiler chicken by methionine , choline and anticoccidials (Amprolium and Diclazuril) at day 9 post infection and it continues for 12 days .The results revealed that no significant differences in plasma glucose , cholesterol , triglyceride and high density lipoprotein level were observed whereas , significant decrease in the level of uric acid , aspartate aminotransferase (AST) activity and alanine aminotransferase (ALT) activity and also significant increase in the level of plasma protein and albumin were evident in treating groups as compared with control . This may be due to high total protein concentration in the blood serum as there is evidence to suggest the existence of inverse proportion between the total protein concentration and activity of enzymes GOT and GPT in serum and may result in adding amino acids to the diet to reduce the body's need to create energy from sources protein and then reduce the activity of enzymes (ALT) and (AST).