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36,078 results on '"cardiotoxicity"'

20. Cardiotoxicity in Breast Cancer Patients

Author

Sara Mohamed Mohamed Abdel Motaleb, Lecturer of Clinical Pharmacy - Pharmacy Practice Department, Faculty of Pharmacy - Helwan University

Published
2024

25. Cancer Therapy and Exercise Intolerance: The Heart Is But a Part: JACC: CardioOncology State-of-the-Art Review.

Author

Dillon, Hayley, Foulkes, Stephen, Baik, Alan, Scott, Jessica, Touyz, Rhian, Herrmann, Joerg, Haykowsky, Mark, La Gerche, André, and Howden, Erin

Subjects
cardiorespiratory fitness, cardiotoxicity, cardiovascular, exercise, hematology, metabolic, oncology, skeletal muscle function
Abstract

The landscape of cancer therapeutics is continually evolving, with successes in improved survivorship and reduced disease progression for many patients with cancer. Improved cancer outcomes expose competing comorbidities, some of which may be exacerbated by cancer therapies. The leading cause of disability and death for many early-stage cancers is cardiovascular disease (CVD), which is often attributed to direct or indirect cardiac injury from cancer therapy. In this review, the authors propose that toxicities related to conventional and novel cancer therapeutics should be considered beyond the heart. The authors provide a framework using the oxygen pathway to understand the impact of cancer treatment on peak oxygen uptake, a marker of integrative cardiopulmonary function and CVD risk. Peripheral toxicities and the impact on oxygen transport are discussed. Consideration for the broad effects of cancer therapies will improve the prediction and identification of cancer survivors at risk for CVD, functional disability, and premature mortality and those who would benefit from therapeutic intervention, ultimately improving patient outcomes.

Published
2024

45. The Effect of Sodium-Glucose Cotransporter-2 Inhibitors on Cardiovascular Outcomes in Patients With Cancer: A Systematic Review and Meta-Analysis

Author

Agarwal, Siddharth, Qamar, Usama, Fujiwara, Yu, Guha, Avirup, Naqash, Abdul Rafeh, Yang, Eric H, Addison, Daniel, Barac, Ana, and Asad, Zain Ul Abideen

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Cancer, Cardiovascular, Good Health and Well Being, Humans, Sodium-Glucose Transporter 2 Inhibitors, Hypoglycemic Agents, Neoplasms, Glucose, Sodium, Diabetes Mellitus, Type 2, Heart Failure, Cardiovascular Diseases, SGLT-2 inhibitors, cardiotoxicity, meta-analy sis, cancer, heart failure, meta-analysis, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology
Published
2024

46. Cancer Therapy-Associated Pulmonary Hypertension and Right Ventricular Dysfunction: Etiologies and Prognostic Implications

Author

Leiva, Orly, Beaty, William, Soo, Steven, Agarwal, Manyoo A, and Yang, Eric H

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Cardiovascular, Heart Disease, Lung, Cancer, Good Health and Well Being, cardio-oncology, cardiotoxicity, pulmonary hypertension, right ventricular dysfunction, Cardiovascular System & Hematology
Published
2024

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