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Background. Cubital tunnel syndrome is the second most commonly diagnosed compressive neuropathy of the upper extremity after carpal tunnel syndrome and the most common neuropathy of the ulnar nerve. Objective. To evaluate the results of surgical treatment of patients with cubital tunnel syndrome by performing an open decompression in situ. Methods. All subjects underwent a standard operation – open surgical opening of the elbow canal (decompression in situ). On the day of surgery, after 3 months, after 6 months, pain (verbal pain scale), hand and arm function (QuickDASH), complications are evaluated. Results. There were 44 patients, 16 (36%) female, 28 (64%) male. In 50% of the patients, electroneuromyography revealed a severe degree of ulnar nerve damage, in the rest – a moderate degree of damage. Hand function for women 3 months after surgery improved by 42.046 points (according to QuickDASH), while in men it was 15.454 points (p < 0.05). Meanwhile, hand function for woman 3 months after surgery improved by 45.833 points, while in men it was 20.000 points (p < 0.05). Statistically significant differences between the groups with a moderate and severe degree of damage were found only when assessing pain according to the VAS scale at 3 months after surgery (mean VAS scores 1.2 and 2.8 respectively). A positive correlation was also observed between age and improvement in hand function between 3–6 months after surgery (p < 0.05). In older people, improvement in hand function is observed after a longer period of time after surgery, and a more pronounced improvement in hand function with a severe degree of damage (comparing function before surgery and 6 months after surgery) is experienced by younger people. Conclusions. In situ decompression of the ulnar nerve is one of the most effective methods of treating ulnar neuropathy. With this method an improvement in the function of the hand and a decrease in pain are observed. [ABSTRACT FROM AUTHOR]

Background. The thickening of A1 pulley of the tendon sheath limits the excursion of flexor tendon. Stenosing tenosynovitis causes finger movements dysfunction and pain. Objective. To analyze early and late outcomes of patients with stenosing tenosynovitis after surgical treatment - anulotomy. Methods. All patients had standard surgical procedure - open anulotomy of A1 pulley. Pain (verbal pain scale), hand and arm function (QuickDASH) and complications were recorded before surgery, after 1 week, 3 months and 6 months post surgery. Results. There were 45 patients, 29 (64%) female, 16 (36%) male. The highest pain score was recorded before surgery median 5 (IQR 5). The lowest pain score median 2 (IQR 2) was recorded after 6 months post surgery. The difference of the results after 1 week, 3 months and 6 months was statistically significant p < 0.001. The worst hand and arm function was before surgery and 1 week post surgery. Accordingly: medians 52 (IQR 33) and 52 (IQR 35). Full hand function recovery was noticed after 6 months post surgery median 0 (IQR 11). The difference is statistically significant p < 0.001. Conclusions. Surgical treatment, open anulotomy is one of the most effective methods for stenosing tenosynovitis. After this procedure pain and hand function improves greatly. However, for some patients it might cause discomfort of the hand because of the scar's sensitivity and location. [ABSTRACT FROM AUTHOR]

Įvadas. Stemplės vėžys (SV) yra aštunta pagal dažnumą onkologinė liga ir šešta mirties dėl vėžio priežastis pasaulyje. Nepaisant pažangos šią ligą diagnozuojant ir gydant, bendrasis 5-erių metų reliatyvus išgyvenamumas siekia 15–25 proc. Straipsnio tikslas – apžvelgti 2008–2017 m. Nacionaliniame vėžio institute (NVI) gydyto SV atvejų gydymo patirtį, įvertinti operacinio, konservatyvaus ir paliatyvaus gydymo rezultatus, nustatyti ligonių išgyvenamumą. Tyrimo metodika. 2008–2017 m. NVI gydėsi 512 pacientų, sergančių SV. Ligoniams taikytas operacinis, paliatyvus operacinis, chemospindulinis, spindulinis, chemoterapinis ar simptominis gydymas. Statistinė analizė atlikta naudojant STATA 11 statistinę programinę įrangą. Rezultatai. Tirtų pacientų amžiaus vidurkis – 61,8 metai. Iš 512 tiriamųjų 63 buvo moterys (12,3 %), 449 – vyrai (87,7 %). I stadijos vėžiu sirgo 25 (4,9 %), II stadijos vėžiu – 74 (14,4 %), III stadijos vėžiu – 258 (50,4 %), IV stadijos vėžiu – 155 (30,3 %) pacientai. Dažniausia morfologija – plokščialąstelinė karcinoma (445 atvejai, 86,9 %), adenokarcinoma – 48 atvejai (9,4 %). Operuoti radikaliai – 75 (14,6 %), paliatyviai – 271 ligonis. Chemospindulinis gydymas taikytas 97 (19,0 %) ligoniams, spindulinis – 81 (15,8 %), chemoterapinis – 111 (21,7 %), simptominis – 148 (28,9 %). Po radikalių operacijų komplikacijų dažnis – 46,17 proc., mirtingumas – 10,67 proc. Dažniausia komplikacija – fistulė. Bendrasis reliatyvus išgyvenamumas: vienus metus – 33,91 proc., penkerius metus – 9,0 proc. Atsižvelgiant į gydymo rūšį, reliatyvusis 5-erių metų išgyvenamumas po radikalių operacijų siekė 26,53 proc., po chemospindulinio gydymo – 17,95 proc., po radioterapinio gydymo – 5,36 proc., po chemoterapinio gydymo – 1,92 proc., po simptominio gydymo – 1,92 proc. Išvados: Po radikalaus SV operacinio gydymo pooperacinių komplikacijų dažnis siekė 46,17 proc., mirtingumas – 10,67 proc. Po paliatyvaus operacinio gydymo komplikacijų dažnis siekė 4,5 proc., mirtingumas – 0,7 proc. NVI gydytų SV sergančiųjų bendrasis 5-erių metų reliatyvus išgyvenamumas – 9,0 proc. Reikšmingos įtakos išgyvenamumui turėjo taikytas gydymas, diagnozuotos ligos stadija ir pirminio naviko dydis.

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Background and purpose. Research shows that pain catastrophizing might be an important predictor of pain related outcomes in patients with various health conditions despite of objective severity of the illness. This study aimed to evaluate prognostic value of catastrophizing the pain in predicting pain intensity before and one day after the surgery for median nerve decompression in a sample of patients with carpal tunnel syndrome (CTS). Methods. 53 patients with electrodiagnostically proven CTS participated in this study. Patients were assessed before and one day after the surgery for median nerve decompression using the Pain Catastrophizing Scale (PCS), and the Short Form of the McGill Pain Questionnaire (SF-MPQ). Intensity of preand acute postoperative pain was evaluated using visual analogue scales. Results. Level of reported pain decreased significantly one day after the surgery. No significant correlations were observed between pain catastrophizing and average level of pain during a week before and one day after the surgery. Correlation was observed between highest experienced level of pain after the surgery and preoperative total PCS score. However, pain catastrophizing did not predict neither preoperative nor acute postoperative pain one day after the surgery in multivariate analyses when other study variables were taken into account. Sensory dimension of SF-MPQ was a better predictor of preoperative pain. None of pain and demographic variables predicted acute postoperative pain. Conclusions. Pain catastrophizing was not found to be a significant predictor of pre- or acute postoperative pain in CTS patients. [ABSTRACT FROM AUTHOR]

Didėjant sergamumui plaučių vėžiu Lietuvoje ir pasaulyje išlieka aktualus gydymo efektyvumo gerinimas. Plaučių vėžys dažniausiai diagnozuojamas vyresniame amžiuje. Nesmulkialąstelis plaučių vėžys sudaro apie 85 %, o smulkialąstelis plaučių vėžys – 15 % visų diagnozuotų plaučio vėžio atvejų. Apie 25 % naujai diagnozuotų nesmulkialąstelio plaučio vėžio atvejų būna I–II stadijos, kitais atvejais, deja, nustatomas vietiškai ar atokiai išplitęs plaučių vėžys, kai chirurginis gydymas negalimas. Ankstyvų stadijų nesmulkialąstelio plaučių vėžio gydymas pradedamas nuo radikalios rezekcinės operacijos, jeigu leidžia ligonio būklė. Po operacijos taikoma adjuvantinė chemoterapija platinos preparatais kartu su etopozidu. Nagrinėti 82 IB–IIIA stadijos nesmulkialąsteliu plaučių vėžių sergantys ligoniai, kuriems atlikta radikali rezekcinė operacija ir paskesnė adjuvantinė chemoterapija. Pooperaciniu 1–2 metų laikotarpiu liga progresavo 22 ligoniams (27 %), o 60-iai ligonių (73 %) buvo ligos remisija. Atsižvelgus į šiuos duomenis būtini papildomi DNR tyrimai, kurie leistų individualizuoti gydymą bei pagerinti jo rezultatus.

Įvadas Duktalinė karcinoma in situ (DCIS) – heterogeniška liga. Įdiegus profilaktinės patikros programą, nustatomų DCIS atvejų sparčiai daugėja. Medžiaga ir metodai Atlikome retrospektyvią pacienčių, operuotų Nacionaliniame vėžio institute dėl DCIS 2010 metais, analizę. NVI duomenų bazėje radome 31-ą tokią pacientę. Pacienčių amžius buvo 46–75 metai, vidurkis – 60 metų. 51,6 % atvejų sudarė didelio laipsnio DCIS, 9,6 % – vidutinio laipsnio DCIS, 32,2 % – mažo laipsnio DCIS, 3,2 % – Pedžeto liga. Dauguma DCIS atvejų estrogenų receptoriai buvo labai jautrūs: 61,3 % pacienčių nustatyti 7–8 Allredo balai iš aštuonių, 32,2 % – estrogenų receptoriai buvo neigiami. Progesteronų receptoriai buvo teigiami 61,3 % atvejų, 35,5 % atvejų – neigiami. Diagnozuojat DCIS dažniausiai, 67,7 % atvejų, buvo atlikta mamografija ir biopsija, kontroliuojama rentgenu, 70,1 % atvejų matomus mamogramose pakitimus radiologai įvertino BI-RADS 4–6 kategorijomis. Rentgenu kontroliuojama biopsija atlikta 45 % atvejų; 29,0 % atvejų biopsija atlikta plona adata. Rezultatai Moterys stebėtos penkerius metus. Viena pacientė mirė dėl kiaušidžių onkologinės ligos po 5 metų, vienai pacientei, praėjus 61 mėnesiui po DCIS operacijos, rastos metastazės pažastyje. Išvados DCIS sirgo maždaug 60 metų moterys, vyravo didelio laipsnio DCIS, turinti labai jautrius estrogenų ir progesteronų receptorius. Stebint 5 metus, nustatytas progresavimas vienai pacientei pažastyje (3,2 %).

Abscesai bei fistulės – dažnai pasitaikantys perianalinės srities dariniai. Paprastai jie būna kriptogeninės kilmės, tačiau juos gali išprovokuoti ir kitos priežastys. Viena jų – į perianalinius audinius patekęs svetimkūnis. Retrogradinis patekimas pastebimas ir iškart sukelia skausmą, o pro burną patekęs svetimkūnis gali likti nepastebėtas ir išbūti organizme ilgą laiką, kol atsiranda ryškūs simptomai. Aprašome retą klinikinį atvejį, kai 42 metų moteris kreipėsi į Vilniaus universiteto ligoninės Santariškių klinikas dėl 7 mėnesius po atliktos pilonidinio sinuso abscesotomijos pūliuojančios pooperacinės žaizdos ir su tuo susijusio skausmo bei diskomforto uodegikaulio srityje. Po papildomų tyrimų atlikta plati abscesotomija ir pašalinti abu tyrimų metu rasti fistulių kanalai. Operacijos metu pūlinio ertmėje rastas svetimkūnis – odontologinis grąžtas, kuris, numanoma, sukėlė abscesus bei fistules. Nurytas svetimkūnis gali ilgai išbūti organizme nepastebėtas. Įsitvirtinęs perianalinėje srityje, sukelia aplinkinių audinių uždegimą. Tinkamai surinkus anamnezę reikėtų įvertinti šios uždegimo etiologijos tikimybę netgi nesant fistulės angų analiniame kanale bei išangėje.

Pakartotinis gimdos plyšimas – tai reta ir itin pavojinga motinos bei vaisiaus gyvybei akušerinė komplikacija. Nepavėluota diagnostika ir gydymas svarbu tiek gelbstint motinos ir vaisiaus gyvybę, tiek užtikrinant gyvenimo kokybę. Šio straipsnio tikslas – pristatyti retą klinikinį pakartotinio gimdos plyšimo po buvusios cezario pjūvio operacijos ir laparoskopinės gimdos miomos pašalinimo operacijos atvejį ir apžvelgti literatūrą, nagrinėjančią gimdos plyšimo nėštumo metu aktualumą, rizikos veiksnius, klinikinius požymius bei gydymą.

Dermatofibrosarcoma protuberans yra itin retas vaikų piktybinis navikas. Nurodoma, kad klasikinė dermatofibrosarkomos forma labai retai metastazuoja, o fibrosarkominei jos transformacijai dažnai būdingos metastazės. Mes aprašome išopėjusios dešiniosios šlaunies dermatofibrosarkomos atvejį septyniolikos metų berniukui. Navikas buvo radikaliai pašalintas. Po vienerių metų atkryčio nerasta.

Nowadays, selection of the best treatment method for intracranial aneurysms is one of the most discussed topics. We report our operative and coiling experience of 128 cases -- series with 106 ruptured and 22 unruptured aneurysms. The aim of the research was to identify the factors influencing the optimal radical method for treatment of intracranial aneurysms and to compare the neurosurgical and neuroradiological activity of our hospital with that of other regions of the world. Of 128 aneurysms the clipped group was 94 patients (mean age ± SD: 52.21 ± 13.34 years, 73.4%) while 34 patients underwent aneurysm embolization (mean age ± SD: 61.59 ± 13.34 years, 36.6%). Most of the aneurysms were located at the anterior communicating artery (n = 36, 28.13%), the middle cerebral artery (n = 34, 26.56%) and the internal carotid artery (n = 20, 15.63%). Comorbidity, neurology status at admission, clinical outcomes, operative complications, aneurysm localization, size and condition were analysed. According to our experience, surgical clipping of aneurysms is more efficient and safe for patients with no or mild comorbidity, with less severe neurological symptoms, ruptured aneurysms, and anterior cerebral circulation aneurysms. [ABSTRACT FROM AUTHOR]

Background. Breast cancer diagnosis is a potential life-threatening event associated with significant distress. The present study aimed to identify the prevalence of posttraumatic stress and its association with clinical and social factors in early breast cancer patients and one year after surgery. Materials and methods. Four hundred twenty one newly diagnosed breast cancer patients completed three questionnaires: Impact of Event Scale - revised (IES-R), Beck Depression Inventory II (BDI-II), Vrana & Lauterbach Traumatic Events Scale-Civilian (TEQ). Women were questioned before surgery and one year later. Patients were 18-80 years old resident Lithuanian women with histologically confirmed breast cancer and no history of other cancers. Additional requirements were as follows: ability to read Lithuanian and being capable of completing a questionnaire. Results. 51.5% of newly diagnosed breast cancer patients had from moderate to severe symptoms of PTSD (score average of IES-R ≥ 1.5). After one year it decreased and there were 33.5% of patients who had symptoms of PTSD. The scores of all subscales were decreased a bit as well. Immediately after statement of diagnosis, PTSD correlated with sadness, often cry and earlier traumatic experience. One year later, PTSD correlated with poor self perception, sadness and traumatic experience during this year. Pessimistic mood, lack of energy, difficulties to concentrate were significant to breast cancer patients. Conclusions. A significant number of breast cancer patients suffers from PTSD symptoms. After one year, the amount of patients suffering from PTSD decreased almost twice. Depression and traumatic experience are the predictors of PTSD. The findings show that early evaluation of psychoemotional needs of breast cancer patients is necessary and early interventions are meaningful. [ABSTRACT FROM AUTHOR]

Following a successful treatment of the first oncological disease, the second malignancy can develop. This retrospective study was designed to evaluate the efficacy of surgical treatment results for patients with the second primary lung cancer (2PLC) depending on the site of the first primary tumor (1PT). Materials and methods. From 2005 to 2009, 88 patients (pts) were treated in the Subdivision of Thoracic Surgery and Oncology, Institute of Oncology, Vilnius University, with lung cancer as the second primary malignancy. 29 patients (33%) underwent surgery: 17 pts (58.6%) - lobectomies, 2 pts (6.9%) - pneumonectomies, 9 pts (31%) - anatomical segmentectomies and 1 pt (3.5%) - bilobectomy. All lung resections were performed with lymph nodes dissection. We had neither major complications nor mortality 30 days after surgery. Stages of 2PLC were as follows: IA-B stage (st.) - 19 pts (65.5%), IIA-B st. - 7 pts (24.1%), and IIIA-IV st. - 3 pts (10.3%). Lung cancer morphology was the following: squamous cell - 11 pts (37.9%), adenocarcinoma - 13 pts (44.8%), large cell carcinoma - 4 pts (13.8%), small cell lung cancer - 1 pt (3.5%). First primaries of the patients were as follows: larynx - 6 pts (207%), lung - 2 pts (6.9%), stomach - 3 pts (10.3%), colon and rectum - 4 pts (13.8%), kidney - 4 pts (13.8%), prostate - 4 pts (13.8%), breast - 2 pts (6.9%), gynecology - 2 pts (6.9%) and haematologic malignancies - 2 pts (6.9%). According to 1PT localization patients were divided into 4 groups: airways, gastrointestinal, urology and other malignancies. Results. 1- and 3-year survival was 69% and 27.6% (60.9% and 30.4% for males; 27.6% and 16.7% for females). 3-year survival for the first primary cancer was 37.5% in urological cancers, 14.3% in gastrointestinal, 37.5% in airway cancers and 16.7% in other cancer cases. Survival by stage of 2PLC was as follows: IA-B st. - 33.3%, IIA-B st. - 28.6%, respectively. No patients survived for 3 years with IIIA-IV st. of 2 PLC. By morphology of 2 PLC there were adenocarcinoma cases in 14.3%, squamous cell carcinoma in 50.0%. One patient with small cell 2 PLC has lived so far. Conclusions. 1. The site of the first primary tumor is not a significant prognostic factor for surgical outcomes of the second primary lung cancer (p > 0.5). 2. Statistically significant survival rates did not differ by gender and histological type of 2PLC. 3. A statistically significant survival difference was obtained only between the patients with IA-IIB st. and IIIA-IV st. of 2PLC (p = 0.0013) [ABSTRACT FROM AUTHOR]

Object. The aim of this report is to evaluate the predictive factors of poor functional outcome in spinal cord meningioma surgery. Materials and methods. One hundred patients with spinal cord meningioma (14 men and 86 women at the age of 13-87) operated in our Neurosurgical Clinic were analyzed. Statistical data analysis evaluated the importance of symptoms, duration and neurological status before surgery and meningioma localization according to the spinal cord axis for the results of surgery. Results. Total tumour removal was achieved in 92 and subtotal in 8 cases. In the early postoperative period, 61% of patients recovered and improved. The results of surgery reliably depended on the duration of symptoms before operation (p = 0.05). The risk of unimprovement prevailed in patients with paraplegia in comparison with other motor deficits. The risk of poor outcome increased with a 95% confidence index when tumour localization was ventral and caudal as compared with the dumbbell, dorsal and epidural localization taken together. Mortality was 3% after the subtotal removal of tumour, and in 3% of cases neoplasma recurred. The mean follow up was 1-22 years. The outcome at the last followup was good in 50% of cases. Conclusions. Functional outcome after surgery reliably dependeds on: 1) the duration of symptoms before hospitalization (with a poor outcome when the duration of illness was more than 3 years); 2) the preoperative neurological condition of patients (a poor prognosis in paraplegic patients); 3) tumour localization with respect to the spinal cord axis (risk of unimprovement when the tumour was of ventral and caudal localization). [ABSTRACT FROM AUTHOR]

Dogs and, less frequently, cats are commonly affected by infections of the external and middle ear (Otitis externa and media). Cocker Spaniels, Dachshunds, Bassets, Golden Retreviers and German Shepherds are notoriously susceptible to repeated ear infections. Cats resistance to the ear disease is significantly higher compared to dogs, although there are breeds (e.g. Persians) which are rather susceptible. Treatment of ear infections depends on the severity of the problem. Simple infections can usually be treated successfully medically. In cases where the infection does not respond to medical management, or in cases where the infection recurs, surgery might be necessary. The article aims to review most frequent causes predisposing surgical intervention as well as to describe procedures and surgical methods being applied in the treatment of inflammation of external and middle ear. Predisposing, persistant or initial factors causing inflammation of external and middle ear are frequently resulting in surgical treatment of the ear. The techniques for tumour and polips removal, as well as surgical methods such as removing the entire vertical canal (called a Vertical Canal Ablation) or just the wall of the vertical canal (called a Lateral Wall Resection, or a Zepp Procedure), and more radical surgery such as a Total Ear Canal Ablation, lateral and ventral Bulla Osteotomy are reviewed. Their advantages and shortcomings are also analyzed. [ABSTRACT FROM AUTHOR]

Amounts of total glutathione (GSH), malondialdehyde (MDA), catalytic activities of catalase (CAT) and glutathione S-transferase (GST) in serum of gastric and colorectal cancer patients were investigated to determine the dynamics of antioxidative system status under surgical treatment. Materials and Methods. 37 gastric and 51 colorectal cancer patients of early (I, II) and advanced (III, IV) stages treated by surgery were included. MDA was tested by thiobarbituric acid (TBA) assay. GSH was determined using recycling system by 5,5-ditiobis(2-nitrobenzoic) acid (DTNB) known as Ellman's reagent (DTNB) and glutathione reductase (GR). CAT was defined under formation of a hydrogen peroxide/ammonium molybdate complex. GST was measured by formation of GSH/1-chloro-2, 4-dinitrobenzene (CDNB) conjugate. Results. MDA and GSH amounts decreased, and GST activity increased in 1 week and 2 weeks after the surgical treatment of both gastric and colorectal cancer patients if compared with the pre-surgical period. MDA level and CAT activity were also diminished comparing the indices of 1 week and 2 weeks post-surgical period. CAT activity decreased only in the post-surgical period of 2 weeks for gastric cancer patients while the parameter dropped for both 1 week and 2 weeks period colorectal cancer patients. A lower GSH amount was detected for advanced stages (III + IV) gastric cancer patients 1 week after the surgery. GST activity was higher for early stages (I + II) only prior to the treatment. No significant differences among the stages were determined for colorectal cancer patients as well as between two age groups (20-59 and 60 + years old) for both cancer localizations. Conclusions. The duration of post-surgical period affects antioxidative system parameters. No reliable differences were determined for most parameters pairs comparing early to advanced cancer stages. The age was shown to be not essential reason of dynamics of the parameters and the process was rather dependent on the tumour localization. [ABSTRACT FROM AUTHOR]

The aim of the study was to evaluate the role of neoadjuvant and adjuvant therapy of non-small-cell lung cancer (NSCLC). Most of patients (pts) were diagnosed in stage III of the disease. Follow-up results of these pts were not satisfactory: within two years after surgery many pts died from a local relapse of tumour or of the progression of disease. Adjuvant treatment (radiotherapy, chemotherapy) could improve the survival of pts. Materials and methods. At Thoracic Surgery Department of the Institute of Oncology, 2535 pts were treated surgically in the course of 54 years (1950-2003). Non-small-cell lung cancer was diagnosed in 2122 of these pts: 1534 pts had squamous cell carcinoma, 561 adenocarcinoma, 27 large cell carcinoma. This is a study of a combined treatment of 288 pts with NSCLC. Two groups of pts were investigated: group I of 140 pts who received adjuvant therapy, and group II of 148 control pts who were treated only surgically. In group I there were three subgroups. In subgroup 1, 54 pts after radical operation received four courses of chemotherapy (cisplatin + vinblastin) or radiotherapy. In subgroups 2 all pts were treated with radiotherapy. 26 pts of subgroup 2 received preoperative radiotherapy (7 Gy and 20 Gy). In subgroup 3, 48 pts received neoadjuvant therapy: two courses of chemotherapy (taxol and carboplatin) and after operation three courses of chemotherapy. Results. The median survival of subgroup I pts was 23.1 (8.7÷27.5) months and of control pts 13 (10.1÷15.9). The median survival of 26 pts subgroup II was 19.9 (11.9÷26.5) months and of control pts 13.58 (10.4÷16.7). The median survival of 48 pts from subgroup III was 22.0 ± 2 months and of control pts 17.2 ± 2 months. Conclusions. Adjuvant therapy of NSCLC improved the follow-up results of treatment 2. Pre- and postoperative radiotherapy can be recommended as adjuvant therapy for NSCLC. 3. Chemotherapy with taxol improves surgical treatment conditions. [ABSTRACT FROM AUTHOR]

Breast conserving surgery or mastectomy are used in early stages of breast cancer treatment. The aim of the study was to establish social factor (age, marital status and occupation) influence on the patient's quality of life after mastectomy and breast conserving surgery. Materials and methods. The quality of life of 62 women with stage I-II of breast cancer treated in the Department of Breast Surgery and Oncology of the Institute of Oncology, 5-6 days after the operation were evaluated by the EORTC QLQ-C30, EORTC QLQ-Br23 and FACT-An questionnaires; also, a questionnaire on the occupation and marital status was used. The quality of life was compared after mastectomy and breast conserving surgery. Results. In younger women, better results were found after breast conserving surgery than after mastectomy according to the EORTC QLQ-C30 Role functioning scale data (p = 0.085). The quality of life of retired women was better after breast conserving surgery than after mastectomy according to the EORTC QLQ-C30 Social functioning scale data (p = 0.044). Some results of the FACT-An and EORTC QLQ-C30 showed a better quality of life after mastectomy than after breast conserving surgery in elder, employed and unmarried women (p < 0.05). Conclusions. The patients' quality of life after mastectomy or breast conserving surgery depends on social factors: age, marital status and occupation. [ABSTRACT FROM AUTHOR]