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9 results on '"da Fonseca, Thamirys Silva"'

1. Brazilian Medicinal Plants with Antiamyloidogenic Activity

Author

Campos, Mariana Freire, da Silva, Celimar Sinezia, do Nascimento, Talita Pimenta, da Fonseca, Thamirys Silva, da Silva, Aline Soares, de Sá Ribeiro, Fernando, Leitão, Fernanda, Leitão, Gilda Guimarães, Lima, Luís Maurício T. R., and Leitão, Suzana Guimarães

Published
2023
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4. Myrtucommulones and Related Acylphloroglucinols from Myrtaceae as a Promising Source of Multitarget SARS-CoV-2 Cycle Inhibitors

Author

Mendonça, Simony Carvalho, primary, Gomes, Brendo Araujo, additional, Campos, Mariana Freire, additional, da Fonseca, Thamirys Silva, additional, Esteves, Maria Eduarda Alves, additional, Andriolo, Bruce Veiga, additional, Cheohen, Caio Felipe de Araujo Ribas, additional, Constant, Larissa Esteves Carvalho, additional, da Silva Costa, Stephany, additional, Calil, Pedro Telles, additional, Tucci, Amanda Resende, additional, Oliveira, Thamara Kelcya Fonseca de, additional, Rosa, Alice dos Santos, additional, Ferreira, Vivian Neuza dos Santos, additional, Lima, Julia Nilo Henrique, additional, Miranda, Milene Dias, additional, da Costa, Luciana Jesus, additional, da Silva, Manuela Leal, additional, Scotti, Marcus Tullius, additional, Allonso, Diego, additional, Leitão, Gilda Guimarães, additional, and Leitão, Suzana Guimarães, additional

Published
2024
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7. In vitro α-glucosidase inhibition by Brazilian medicinal plant extracts characterised by ultra-high performance liquid chromatography coupled to mass spectrometry

Author

Lianza, Mariacaterina, primary, Poli, Ferruccio, additional, Nascimento, Alan Menezes do, additional, Soares da Silva, Aline, additional, da Fonseca, Thamirys Silva, additional, Toledo, Marcos Vinicius, additional, Simas, Rosineide Costa, additional, Chaves, Andréa Rodrigues, additional, Leitão, Gilda Guimarães, additional, and Leitão, Suzana Guimarães, additional

Published
2022
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8. Antifungal Phenylpropanoid Glycosides from Lippia rubella

Author

Martins, Gabriel R., primary, da Fonseca, Thamirys Silva, additional, Martínez-Fructuoso, Lucero, additional, Simas, Rosineide Costa, additional, Silva, Fabio T., additional, Salimena, Fatima Regina G., additional, Alviano, Daniela S., additional, Alviano, Celuta Sales, additional, Leitão, Gilda Guimarães, additional, Pereda-Miranda, Rogelio, additional, and Leitão, Suzana G., additional

Published
2019
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9. Antifungal Phenylpropanoid Glycosides from Lippia rubella

Author

Martins, Gabriel R., da Fonseca, Thamirys Silva, Martínez-Fructuoso, Lucero, Simas, Rosineide Costa, Silva, Fabio T., Salimena, Fatima Regina G., Alviano, Daniela S., Alviano, Celuta Sales, Leitão, Gilda Guimarães, Pereda-Miranda, Rogelio, and Leitão, Suzana G.

Abstract

Lippiaspecies share various pharmacological activities and are used in traditional cooking and medicine worldwide. Combined chromatographic techniques such as column chromatography, high-performance liquid chromatography, and countercurrent chromatography led to the purification of two new antifungal phenylpropanoid glycosides, lippiarubelloside A (1) and lippiarubelloside B (2), by bioactivity-directed fractionation of an ethanol-soluble extract from Lippia rubella, in addition to the known active related compounds forsythoside A (3), verbascoside (4), isoverbascoside (5), and poliumoside (6). The structures of compounds 1and 2were determined by comparison of their NMR spectroscopic data with the prototype active compound 4. Cryptococcus neoformans, which causes opportunistic lung infections, was sensitive to compounds 1–6in the concentration range of 15–125 μg/mL. A synergistic effect (FICindex= 0.5) between 3and amphotericin B was demonstrated. The glycosylated flavonoids pectolinarin (7), linarin (8), and siparunoside (9) were also isolated.

Published
2018
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