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139 results on '"da Silva Barros, Caio César"'

7. Squamous cell carcinoma and basal cell carcinoma of the lips: 25 years of experience in a northeast Brazilian population.

Author

Rodrigues da Silva, Weslay, Moura de Bortoli, Manoela, Silveira Leite, Sérgio Ricardo, da Silva Barros, Caio César, de Fátima Medeiros Brito, Maria, Tavares Montenegro, Luciano, Holanda Vasconcellos, Ricardo José, Paraíso Iglesias, Deborah Pitta, and Veras Sobral, Ana Paula

Subjects
BASAL cell carcinoma, SQUAMOUS cell carcinoma, FISHER exact test, SURGICAL margin, BRAZILIANS
Abstract

Background: The lips are the transition zone between the facial skin and the oral mucosa and are the site of alterations related to a broad spectrum of etiologies. Squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) are the most prevalent neoplasms affecting lips. This study evaluated the demographic and clinicopathological features of the SCC and BCC in the lip. Material and Methods: A retrospective cross-sectional descriptive study (1994-2019) was carried out. Demographic and clinicopathologic data were collected from a hospital’s dermatological service and an oncologic hospital. The data were submitted to descriptive analysis and Pearson's chi-square and Fisher's exact tests (p ≤ 0.05). Results: 417 medical records were analyzed, of which 323 corresponded to SCC (77.5%) and 94 to BCC (22.5%). SCC showed more frequency in males (58.8%) and BCC in females (54.3%). The lower lip was significantly affected in male patients (p < 0.0001) and by both neoplasms (70.6% and 56.4%, respectively; p = 0.014). SCC and BCC were mainly treated with surgery (88.3% and 93.2%, respectively). Surgical margin was frequently negative in SCC and BCC (87%; 72.3%, respectively), and no recurrence was observed in 79.9% of SCC and 69.1% of BCC cases. Conclusions: SCC was more frequent in male patients, while BCC showed more frequency in female patients. Both neoplasms mainly affect the lower lip. Understanding the epidemiological profile of these lesions in the lip, as well as their etiology and clinical features, is fundamental for appropriate clinical conduct and the creation and/or amplification of preventive measures. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Ameloblastoma recurrence associated with ameloblastic fibroma: A unusual case report of a hybrid odontogenic tumor.

Author

da Silva Barros, Caio César, de Souto Medeiros, Maurília Raquel, da Costa Miguel, Márcia Cristina, Germano, Adriano Rocha, and da Silveira, Éricka Janine Dantas

Abstract

Hybrid odontogenic tumors are characterized by presenting histopathological features of two or more distinct odontogenic lesions. Here we report a hybrid odontogenic tumor case composed of an ameloblastoma (AM) recurrence associated with ameloblastic fibroma (AF). A 60-year-old male patient underwent a clinical follow-up of an AM surgically treated 10 years ago. The computed tomography scan identified an isodense osteolytic lesion partially obliterating the left maxillary sinus. Due to the medical history, the clinical hypothesis was AM recurrence. Microscopic examination revealed a benign odontogenic neoplasm showing areas of ameloblastomatous epithelium proliferation in a dense connective tissue stroma and areas of ameloblastic epithelium with a myxoid cell-rich connective tissue. The final diagnosis was AM associated with AF. Hybrid odontogenic lesions are widely discussed, and an accurate microscopic examination is essential to determine their clinical behavior. Due to its sporadic reports, long-term follow-ups are necessary to better understand their prognosis. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Effect of polyphenols on tissue engineering outcomes: A systematic review protocol

Author

Nunes, Gabriel Pereira, Reis-Prado, Alexandre Henrique Dos, De Toledo, Priscila Toninatto Alves, Dal-Fabbro, Renan, Bottino, Marco, Santos, Juliana Amorim Dos, and Da Silva Barros, Caio César

Subjects
FOS: Nanotechnology, Dentistry, FOS: Clinical medicine, #biomaterials, Medicine and Health Sciences, #tissue engineering, Nanotechnology, #polyphenols, Chemicals and Drugs, Biomedical and Dental Materials
Abstract

In tissue engineering, polyphenol-based biomaterial scaffolds have been widely observed because of their excellent functional properties, including adhesiveness, antioxidant properties, antimicrobial capabilities and biocompatible properties (Zhang et al., 2021). The omnipresence, specificity of the response and the absence/low toxicity are also important advantages of polyphenols as anticancer agents (Ramos et al., 2008). Their main limitations are related to low bioavailability and rapid metabolism (Fantini et al., 2015). Thus, despite their low bioavailability, polyphenols may be a promising option for tissue regeneration.

Published
2023
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30. Intraosseous rhabdomyosarcoma of the maxilla with TFCP2 fusion: A rare aggressive subtype with predilection for the gnathic bones

Author

Silva Cunha, John Lennon, primary, Cavalcante, Israel Leal, additional, da Silva Barros, Caio César, additional, Alves, Pollianna Muniz, additional, Nonaka, Cassiano Francisco Weege, additional, Albuquerque, Assis Filipe Medeiros, additional, de Almeida, Oslei Paes, additional, de Andrade, Bruno Augusto Benevenuto, additional, and Cavalcante, Roberta Barroso, additional

Published
2022
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31. The stromal immunoexpression of CLIC4 may be related to the difference in the biological behavior between oral squamous cell carcinoma and oral verrucous carcinoma.

Author

Carvalho Xerez, Mariana, da Silva Barros, Caio César, Monteiro Lourenço Queiroz, Salomão Israel, Dantas da Silveira, Éricka Janine, and Lopes Costa, Antonio de Lisboa

Subjects
SQUAMOUS cell carcinoma, CARCINOMA, EPITHELIAL cells, RANK correlation (Statistics), CELL cycle regulation, MYOFIBROBLASTS
Abstract

Background: Oral squamous cell carcinoma (OSCC) has high morbidity and mortality rates while oral verrucous carcinoma (OVC), an uncommon variant of OSCC, exhibits a distinct biological behavior. CLIC4 protein plays a role in the cell cycle and apoptosis regulation and participates in the myofibroblasts transdifferentiation process, which are the main cells of the tumor stroma. This study analyzed the immunoexpression of CLIC4 and a-SMA in 20 OSCC cases and 15 OVC cases. Material and Methods: A semiquantitative analysis of CLIC4 and a-SMA immunoexpression was performed in the parenchyma and stroma. Nuclear and cytoplasmic reactivity was analyzed separately for the CLIC4 immunostaining. The data were submitted to Pearson's chi-square and Spearman's correlation tests (p = 0.05). Results: In the CLIC4 analysis, there was a significant difference in the immunoexpression of this protein between OSCC and OVC stroma (p < 0.001). It was observed a higher expression of a-SMA in the OSCC stroma. There was a positive and significant correlation between CLIC4 and a-SMA immunoexpression in the OVC stroma (r = 0,612; p = 0,015). Conclusions: The decrease or absence of nuclear CLIC4 immunoexpression in the neoplastic epithelial cells and the increase of its expression in the stroma may influence the difference in biological behavior between OSCC and OVC. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Peripheral ossifying fibroma: A 20-year retrospective study with focus on clinical and morphological features.

Author

Leal Cavalcante, Israel, da Silva Barros, Caio César, Sousa Cruz, Vitória Maria, Silva Cunha, John Lennon, Carneiro Leão, Lara Cunha, Roque Ribeiro, Renata, Turatti, Eveline, Benevenuto deAndrade, Bruno Augusto, and Barroso Cavalcante, Roberta

Subjects
FIBROMAS, CONNECTIVE tissues, RETROSPECTIVE studies, GINGIVAL hyperplasia, GINGIVAL diseases
Abstract

Background: Peripheral Ossifying Fibroma (POF) is a reactive hyperplastic lesion that exclusively occurs in the gingiva and is characterized by the deposition of dystrophic calcification, cementum-like tissue, and immature and mature bone within the connective tissue. The objective of the present study was to perform a retrospective analysis of clinicopathologic features of POF. Material and Methods: Clinical and histopathological data were obtained from biopsy records and histopathological reports from a Brazilian reference service in Oral Pathology (1999 - 2020). Morphological analysis was performed to evaluate features related to the mesenchymal component, inflammatory infiltrate, ulceration, and mineralized tissue. Results: A total of 270 POFs were diagnosed during the study period. A higher frequency was observed in females (71.9%) between the third (22.9%) and fourth (23.3%) decades of life. The anterior upper gingiva (29.1%) was the most affected region. Mature (86.7%) and immature (52.6%) bone tissue were the most frequent. There was a significant association between immature bone deposition and lesions with size = 1.7 cm (p = 0.041); immature bone and cement-like tissue deposition with an evolution time = 16 months (p < 0.001); deposition of immature bone and mesenchymal hypercellularization (p < 0.001); deposition of dystrophic calcification and the presence of ulceration (p < 0.001). Conclusions: The clinical characteristics corroborate the findings in the literature. The heterogeneous distribution and quantity of mineralized tissues found in the analyzed cases support the theory that the different mineralized tissues constitute a spectrum of clinical maturation of POF. [ABSTRACT FROM AUTHOR]

Published
2022
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39. ORAL KAPOSI SARCOMA: A CASE REPORT

Author

CAVALCANTE, ISRAEL LEAL, primary, DA SILVA BARROS, CAIO CÉSAR, additional, DE FREITAS RÊGO, FRANCISCO SENA, additional, PIÑA, ALICIA RUMAYOR, additional, DE ALMEIDA, OSLEI PAES, additional, CAVALCANTE, ROBERTA BARROSO, additional, and TURATTI, EVELINE, additional

Published
2020
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40. PERIPHERAL COMPOUND ODONTOMA: CASE REPORT

Author

DE OLIVEIRA COSTA, CARLA SAMILY, primary, DA SILVA ROCHA, ONDINA KARLA MOUSINHO, additional, DA SILVA BARROS, CAIO CÉSAR, additional, DANTAS, AFONSO NÓBREGA, additional, DA SILVA, LUIZ ARTHUR BARBOSA, additional, DE MORAIS, HÉCIO HENRIQUE ARAÚJO, additional, and DA COSTA MIGUEL, MÁRCIA CRISTINA, additional

Published
2020
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42. CONGENITAL EPULIS: CASE REPORT

Author

RODRIGUES, KATIANNE SOARES, primary, DA SILVA ROCHA, ONDINA KARLA MOUSINHO, additional, DA SILVA BARROS, CAIO CÉSAR, additional, DANTAS, AFONSO NÓBREGA, additional, DA SILVA, LUIZ ARTHUR BARBOSA, additional, PAIES, MARINA BOZZINI, additional, and DA COSTA MIGUEL, MÁRCIA CRISTINA, additional

Published
2020
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43. Angina bullosa haemorrhagica: A 14-year multi-institutional retrospective study from Brazil and literature review.

Author

Silva-Cunha, John Lennon, Cavalcante, Israel Leal, da Silva Barros, Caio César, Felix, Fernanda Aragão, Venturi, Luan Borges, Amaral Rolim, Larissa Santos, Porpino Santos da Silva-Júnior, César Luis, Sousa, Emanuel Mendes, Dantas da Silveira, Éricka Janine, Agostini, Michelle, Romañach, Mário José, de Almeida, Oslei Paes, de Sousa, Sílvia Ferreira, and Benevenuto de Andrade, Bruno Augusto

Subjects
ANGINA pectoris, SOFT palate, LITERATURE reviews, THERAPEUTICS, MEDICAL records, ORAL mucosa
Abstract

Background: Angina bullosa haemorrhagica (ABH) is characterized by the recurrent appearance of blood blisters on the oral mucosa, mainly in adults' soft palate. In general, the blisters rupture spontaneously, lacking the necessity for biopsy. We report the clinical features of 23 ABH cases, emphasizing the clinical behavior and the management of these conditions. Material and Methods: A retrospective descriptive cross-sectional study was performed. A total of 12,727 clinical records of oral and maxillofacial lesions from four dental services in Brazil were analyzed. Clinical data were collected from the clinical records and evaluated. Results: The series comprised 12 males (52.2%) and 11 females (47.8%), with a mean age of 56.8±14.6years (ranging: 24-82years) and a 1.1:1 male-to-female ratio. Most of the lesions affected the soft palate (n = 15, 65.2%). Clinically, the lesions presented mainly as an asymptomatic (n = 17, 73.9%) blood-filled blister that ruptured after a few minutes or hours, leaving an erosion. The masticatory trauma was the most frequent triggering event. No patient had coagulation disorders. A biopsy was performed in only four cases (17.4%). Treatment was symptomatic with a favorable outcome. Conclusions: ABH is still poorly documented in the literature, and its etiology remains uncertain. ABH mainly affects the soft palate of elderly adults and has a favorable evolution in a few days. The therapeutic approach is often focused only on the relief of symptoms. However, it can share some clinical features with more serious diseases. Therefore, clinicians must recognize these lesions to avoid misdiagnosis. [ABSTRACT FROM AUTHOR]

Published
2022
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45. Clinicopathologic features of nasopalatine duct cysts: A retrospective study in two Brazilian oral and maxillofacial pathology referral centers.

Author

Leal Cavalcante, Israel, da Silva Barros, Caio César, Silva Cunha, John Lennon, Sousa Cruz, Vitória Maria, Alves Pedrosa, Gabriele, de Jesus Santos, Amanda, Turatti, Eveline, Cavalcanti de Albuquerque-Júnior, Ricardo Luiz, and Barroso Cavalcante, Roberta

Subjects
MULTINUCLEATED giant cells, PATHOLOGY, HISTOPATHOLOGY, SEBACEOUS glands, PTERYGOPALATINE ganglion, DIAGNOSIS, ORAL mucosa
Abstract

Background: Nasopalatine duct cyst (NDC) is the most common non-odontogenic cyst in the oral cavity. Clinically it is not difficult to suspect these lesions based on clinical and radiographic appearance. However, the histopathological diagnosis may be difficult due to the broad morphological diversity of these lesions. The objective was to analyze the clinicopathological features of NDCs diagnosed in two oral and maxillofacial pathology services in the Brazilian northeast. Material and Methods: A retrospective clinicopathologic study was performed. A total of 18,121 clinical records of oral lesions from two oral and maxillofacial pathology services in Brazil were analyzed (2000-2020). All NDCs cases were revised and demographic, clinical, radiographic, and histopathological data were collected. Results: Among 18,121 diagnoses in the oral pathology services, 45 (0.2%) were NDCs. The series comprises 24 males (53.3%) and 21 females (46.7%), with a mean age of 43.2 years-old. Most lesions were asymptomatic (n = 27, 60%) with an mean size of 2.1 cm. Microscopically, the non-keratinized stratified squamous epithelium was the most common (66.7%). However, in 88.9% of cases, the epithelial lining was varied and composed of two or more types of epithelium. There was no significant association between the type of epithelium and the size of the cysts (p = 0.389). Nerve, blood vessels, hemorrhage, and chronic inflammatory infiltrate were commonly observed. In contrast, there was a low frequency of mucous glands, sebaceous glands, cholesterol clefts, and multinucleated giant cells. Conclusions: The clinical, radiographic, and microscopic findings observed in this study are similar to those reported in the literature. Due to the morphological diversity of NDC, it is needed to correlate its histopathological features with the clinical and radiographic findings to establish a correct diagnosis. [ABSTRACT FROM AUTHOR]

Published
2021
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49. Intraosseous Squamous Cell Carcinoma: a Case Report

Author

Xerez, Mariana Carvalho, primary, Leite, Rafaella Bastos, additional, Da Silva Barros, Caio César, additional, Da Silva Castro, Luciana Eloisa, additional, Moreira-Júnior, Luiz Carlos, additional, Germano, Adriano Rocha, additional, and De Lisboa Lopes Costa, Antonio, additional

Published
2018
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50. Lymphoepithelial Cyst in the Posterior Tongue: a Case Report

Author

Xerez, Mariana Carvalho, primary, Da Silva Castro Nóbrega, Luciana Eloísa, additional, Leite, Rafaella Bastos, additional, Da Silva Barros, Caio César, additional, Cavalcante, Israel Leal, additional, De Lucena Pereira, Laudenice, additional, and De Lisboa Lopes Costa, Antônio, additional

Published
2018
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