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3. Contributors

Author

Abrahamsson, Kate, primary, Albersen, Maarten, additional, Alberts, Arnout, additional, Amend, Bastian, additional, Amesty, Maria Virginia, additional, Aminoff, Dalia, additional, Ammirati, Enrico, additional, Andersson, Marie, additional, Bartezzati, Rita Serena, additional, Battye, Michelle, additional, Benavent, Patricia Gavín, additional, Bidault, Valeska, additional, Bientinesi, Riccardo, additional, Blasco-Amaro, Juan Antonio, additional, Bolz-Johnson, Matthew, additional, Boormans, Lotte, additional, Brits, Tim, additional, Brouwer, Oscar R., additional, Brucker, Sara, additional, Buchler, Tomas, additional, Campos-Juanatey, Felix, additional, Carmona-Hidalgo, Beatriz, additional, Chapple, Christopher R., additional, Che, Yue, additional, Chrzan, Rafal, additional, Cornes, Robert, additional, de Blaauw, Ivo, additional, de Kort, Laetitia M.O., additional, De Win, Gunter, additional, Dellenmark-Blom, Michaela, additional, Demede, Delphine, additional, El-Ghoneimi, Alaa, additional, Ellerkamp, Verena, additional, Esteban, Mario Dominguez, additional, Falcone, Marco, additional, Feitz, Wouter F.J., additional, Filipas, Dejan, additional, Fisch, Margit, additional, Fossum, Magdalena, additional, Fröbe, Ana, additional, Fruehling, Insa, additional, Fuchs, Jörg, additional, Giammo, Alessandro, additional, González-Bermúdez, Lourdes, additional, Graaf, Petra de, additional, Grupp, Katharina, additional, Hageman, Isabel C., additional, Harkin, Claire, additional, Heesakkers, John, additional, Holmdahl, Gundela, additional, Hompes, Daphne, additional, Janssen, Dick, additional, Jouannic, Jean Marie, additional, Kirrander, Peter, additional, Klemm, Jakob, additional, Kulis, Tomislav, additional, Langenhuijsen, Johan, additional, Leclair, Marc-David, additional, Ludwig, Tim, additional, Mancini, Mariangela, additional, Manzie, Kenneth, additional, Martín-Gómez, Carmen, additional, Medina-Polo, José, additional, Meister, Benjamin, additional, Midrio, Paola, additional, Miletić, Marija, additional, Morlacco, Alessandro, additional, Moro, Fabrizio Dal, additional, Mosiello, Giovanni, additional, Nieder, Timo, additional, Nijman, Rien, additional, Oomen, Loes, additional, Örtqvist, Lisa, additional, Osborne, John, additional, Paye-Jaouen, Annabel, additional, Peycelon, Matthieu, additional, Philippe-Chomette, Pascale, additional, Polm, Pepijn, additional, Radmayr, Christian, additional, Rall, Katharina, additional, Rawashdeh, Yazan F., additional, Riechardt, Silke, additional, Rivas, Susana, additional, Roozen, Sylvia, additional, H. Rösch, Wolfgang, additional, Sacco, Emilio, additional, Santis, Anna De, additional, Schmiedeke, Eberhard, additional, Schwarzer, Nicole, additional, Shilhan, Darren, additional, Solak, Mirsala, additional, Spinoit, Anne-Françoise, additional, Stallings, Elena, additional, Stein, Raimund, additional, Steinmacher, Sahra, additional, Subramaniam, Ramnath, additional, Tidman, Jen, additional, Tyler, Kate, additional, van der Steeg, Herjan J.J., additional, van der Zanden, Loes F.M., additional, Vetterlein, Malte W., additional, Vicente-Edo, María José, additional, Vreeburg, Manon T.A., additional, Witjes, Wim P.J., additional, Wolffenbuttel, Katja P., additional, Wyndaele, Michel I.A., additional, Younsi, Nina, additional, and Zuiverloon, Tahlita, additional

Published
2024
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11. Wat moet de volwassenuroloog weten van de kinderurologie?

Author

Stillebroer, Alexander B., Trompetter, Marleen, de Kort, Laetitia M.O., Stillebroer, Alexander B., Trompetter, Marleen, and de Kort, Laetitia M.O.

Abstract

Congenital urological problems vary from highly prevalent entities such as hypospadias or undescended testicles to extremely rare problems such as bladder exstrophy. Urological care usually ends for these diseases when patients reach the age of 18. However, complications in adult life of these diseases are not uncommon. In this article we provide an overview of some congenital urological anomalies with associated risks and subsequent treatment in adult life.

Published
2024

12. Transitiezorg in de urologie

Author

Stillebroer, Alexander B., Lammers, Rianne J.M., de Kort, Laetitia M.O., Stillebroer, Alexander B., Lammers, Rianne J.M., and de Kort, Laetitia M.O.

Published
2024

13. Very long-term follow-up of Indiana Pouches proves durability

Author

Urologie Onderzoek, Urologie Medisch volwassenen, Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, Polm, Pepijn D., Wyndaele, Michel I.A., de Kort, Laetitia M.O., Urologie Onderzoek, Urologie Medisch volwassenen, Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, Polm, Pepijn D., Wyndaele, Michel I.A., and de Kort, Laetitia M.O.

Published
2024

14. Bladder exstrophy–epispadias complex: The effect of urotherapy on incontinence

Author

Urologie Onderzoek, Incontinentieteam, Urologie Medisch Kinderen, Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, van Geen, Frank Jan, Nieuwhof-Leppink, Anka J., Wortel, Ruud C., de Kort, Laetitia M.O., Urologie Onderzoek, Incontinentieteam, Urologie Medisch Kinderen, Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, van Geen, Frank Jan, Nieuwhof-Leppink, Anka J., Wortel, Ruud C., and de Kort, Laetitia M.O.

Published
2024

15. For Your Eyes Only? The Use of Surgical Videos in Urological Residency Training: A European-wide Survey

Author

Urologie Opleiding, MS Urologische Oncologie, Cancer, Expertisecentrum Alg., Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, van der Leun, Josephine A., Brinkman, Willem M., Pennings, Heleen J.M., van der Schaaf, Marieke F., de Kort, Laetitia M.O., Urologie Opleiding, MS Urologische Oncologie, Cancer, Expertisecentrum Alg., Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, van der Leun, Josephine A., Brinkman, Willem M., Pennings, Heleen J.M., van der Schaaf, Marieke F., and de Kort, Laetitia M.O.

Published
2024

16. Materiaalgebruik in de urologische praktijk: kan het duurzamer?

Author

Urologie Medisch volwassenen, Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, Jansen, Sanne L., Legemate, Jaap D., Leliveld, Annemarie M., de Kort, Laetitia M.O., Urologie Medisch volwassenen, Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, Jansen, Sanne L., Legemate, Jaap D., Leliveld, Annemarie M., and de Kort, Laetitia M.O.

Published
2024

26. List of contributors

Author

Adewole, Dayo O., primary, Afjeh-Dana, Elham, additional, Ahmadi, Ehsaneh Daghigh, additional, Ahmed, Nessar, additional, Alkhalili, Osama A., additional, Amadikuchaksaraei, Ali, additional, Amini, Naser, additional, Amoupour, Moein, additional, Asencio, Ilida Ortega, additional, Ashtari, Khadijeh, additional, Asthana, Amish, additional, Atala, Anthony, additional, Batchelder, Cynthia A., additional, Berthiaume, Francois, additional, Brenner, Michael J., additional, Bulutoglu, Beyza, additional, Burrell, Justin C., additional, Campo, Hannes, additional, Cervelló, Irene, additional, Chaimov, Deborah, additional, Chattopadhyay, Munmun, additional, Chen, Yibin, additional, Coates, Phil, additional, Cullen, D. Kacy, additional, Das, Suradip, additional, de Graaf, Petra, additional, de Kemp, Vincent F., additional, de Kort, Laetitia M.O., additional, Devi, Khangembam Sangeeta, additional, Dewangan, Rukmani, additional, Ekenseair, Adam K., additional, Elzinga, Sarah, additional, Farzi, Gholam Ali, additional, Feldman, Eva L., additional, Fhong, Soon Chin, additional, Finck, Christine, additional, Foster, Christopher, additional, Gaffley, Michaela, additional, Gangwar, Anil Kumar, additional, Gazia, Carlo, additional, Hafeji, Saudah, additional, Hafiz, Ehab, additional, Hancox, Zoe, additional, Hanks, John E., additional, Heidi, Debels, additional, House, Michael D., additional, Hwang, Ji-Young, additional, Jaramillo, Maria, additional, Jensen, Todd, additional, Joddar, Binata, additional, Jo, Inho, additional, Jones, Eyone, additional, Jung, Sung-Chul, additional, Kanetkar, Ninad S., additional, Kang, Hwan June, additional, Kargozar, Saied, additional, Katiyar, Kritika S., additional, Kelangi, Sarah S., additional, Keshel, Saeed Heidari, additional, Khaghani, Seyed Ali, additional, Khangembam, Sangeeta Devi, additional, Kim, Han Su, additional, Koullali, Bouchra, additional, Kumar, Naveen, additional, Kumar, Suneel, additional, Kumar, Vineet, additional, Lahann, Joerg, additional, Lee, Yunki, additional, Long, Jennifer L., additional, Magalhaes, Renata S., additional, Maiti, Swapan Kumar, additional, Milan, Peiman Brouki, additional, Mitchell, Adam, additional, Momeni-Moghadam, Majid, additional, Mozafari, Masoud, additional, Muñiz, Ayșe Jane, additional, Naeem, Chaman, additional, Nair, Karthik, additional, Oh, Se-Young, additional, Oliver, Jeremie D., additional, Orabi, Hazem, additional, Orlando, Giuseppe, additional, Park, Ki Dong, additional, Park, Yoon Shin, additional, Petrov, Dmitriy, additional, Raghuvanshi, P.D.S., additional, Rezapour, Alireza, additional, Santamaria, Xavier, additional, Saxena, Sonal, additional, Sayej, Wael, additional, Sefat, Farshid, additional, Shah, Tejal, additional, Shakeri, Shahryar, additional, Sharma, Ishna, additional, Shrivastava, Sameer, additional, Simón, Carlos, additional, Singh, Ajit Kumar, additional, Singh, Karam Pal, additional, Singh, Naresh Kumar, additional, Sing, S.L., additional, Stebbins, Aaron W., additional, Tan, E.Y.S., additional, Tarantal, Alice F., additional, Tasnim, Nishat, additional, Topal, Tuğba, additional, Torres, Herminio M., additional, Tsachouridis, George, additional, Uygun, Basak E., additional, Vyas, Krishna S., additional, Wanczyk, Heather, additional, Wang, Hongjun, additional, Wayne, Morrison, additional, Yeong, W.Y., additional, Yousaf, Safiyya, additional, Youseffi, Mansour, additional, and Zhang, Wei, additional

Published
2019
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27. Extracellular matrix analysis of fibrosis:A step towards tissue engineering for urethral stricture disease

Author

Linssen, Emma C., Demmers, Jeroen, van Dijk, Christian G.M., van Dam, Roos, Nicese, Maria Novella, Cheng, Caroline, de Kort, Laetitia M.O., de Graaf, Petra, Linssen, Emma C., Demmers, Jeroen, van Dijk, Christian G.M., van Dam, Roos, Nicese, Maria Novella, Cheng, Caroline, de Kort, Laetitia M.O., and de Graaf, Petra

Abstract

The urogenital tract is a target for many congenital and acquired diseases, both benign and oncogenic. In males, the urethra that transports urine and semen can be obstructed by a fibrotic disease called urethral stricture disease (USD). In severe USD, the whole organ including the vascular embedding, the corpus spongiosum (CS), is affected. Recurrent or severe USD is treated by reconstructive surgery. Tissue engineering may improve the outcome of urethral reconstruction in patients with complicated USD. Currently in urethral reconstruction only the epithelial layer is replaced, no substitution for the CS is provided, while the CS is important for mechanical support and vascularization. To develop a tissue engineering strategy for the CS, it is necessary to know the protein composition of the CS. As the extracellular matrix (ECM) plays an important role in the formation of fibrosis, we analyzed the distribution and localization of ECM components in human healthy and fibrotic CS tissue using immunohistology. The morphology of components of the elastic network were affected in USD. After decellularization a clear enrichment of proteins belonging to the ECM was found. In the proteomic analysis collagens COL15A1 and COL4A2 as well as inter-alpha-trypsin inhibitor ITIH4 were upregulated in fibrotic samples. The glycoproteins Periostin (POSTN), Microfibrillar-associated protein 5 (MFAP5) and EMILIN2 are downregulated in fibrotic tissue. To our knowledge this is the first proteomic study of ECM proteins of the CS in healthy and in USD. With these results a regenerating approach for tissue engineered CS can be developed, including relevant ECM proteins that reduce fibrosis and promote healthy healing in urethral reconstructive surgery.

Published
2023

28. Quantifying bladder outflow obstruction in men: A comparison of four approximation methods exploiting large data samples

Author

Urologie Medisch Kinderen, Urologie Medisch volwassenen, Other research (not in main researchprogram), Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, van Dort, Wouter, Rosier, Peter F.W.M., Geurts, Bernard J., van Steenbergen, Thomas R.F., de Kort, Laetitia M.O., Urologie Medisch Kinderen, Urologie Medisch volwassenen, Other research (not in main researchprogram), Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, van Dort, Wouter, Rosier, Peter F.W.M., Geurts, Bernard J., van Steenbergen, Thomas R.F., and de Kort, Laetitia M.O.

Published
2023

29. Dysfunctional Voiding: Exploring Disease Transition From Childhood to Adulthood

Author

Urologie Onderzoek, UMC Utrecht Holding, Urologie Medisch Kinderen, Incontinentieteam, Other research (not in main researchprogram), Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, van Geen, Frank Jan, van de Wetering, Eline H.M., Nieuwhof-Leppink, Anka J., Klijn, Aart J., de Kort, Laetitia M.O., Urologie Onderzoek, UMC Utrecht Holding, Urologie Medisch Kinderen, Incontinentieteam, Other research (not in main researchprogram), Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, van Geen, Frank Jan, van de Wetering, Eline H.M., Nieuwhof-Leppink, Anka J., Klijn, Aart J., and de Kort, Laetitia M.O.

Published
2023

30. Een richtlijn voor inflammatoire blaasaandoeningen?

Author

Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, Janssen, Dick A.W., de Kort, Laetitia M.O., Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, Janssen, Dick A.W., and de Kort, Laetitia M.O.

Published
2023

31. Themapoli voor ketamine-geïnduceerde cystitis: eerste ervaringen en resultaten

Author

Urologie Opleiding, Urologie Medisch volwassenen, Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, van der Sanden, Wouter M.H., Wyndaele, Michel, Schipper, Robert A., de Kort, Laetitia M.O., Urologie Opleiding, Urologie Medisch volwassenen, Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, van der Sanden, Wouter M.H., Wyndaele, Michel, Schipper, Robert A., and de Kort, Laetitia M.O.

Published
2023

38. Arterio-ureteral fistula: a nationwide cross-sectional questionnaire analysis

Author

Urologie Onderzoek, Other research (not in main researchprogram), Zorgeenheid Urologie Medisch, Zorgeenheid Vaatchirurgie Medisch, MS Radiologie, Circulatory Health, Urologie Medisch Kinderen, Child Health, Regenerative Medicine and Stem Cells, Lock, Tycho M.T.W., Kamphorst, Kyara, van den Bergh, Roderick C.N., Moll, Frans L., de Vries, Jean Paul P.M., Lo, Rob T.H., de Kort, Gérard A.P., Bruijnen, Rutger C.G., Dik, Pieter, Horenblas, Simon, de Kort, Laetitia M.O., Urologie Onderzoek, Other research (not in main researchprogram), Zorgeenheid Urologie Medisch, Zorgeenheid Vaatchirurgie Medisch, MS Radiologie, Circulatory Health, Urologie Medisch Kinderen, Child Health, Regenerative Medicine and Stem Cells, Lock, Tycho M.T.W., Kamphorst, Kyara, van den Bergh, Roderick C.N., Moll, Frans L., de Vries, Jean Paul P.M., Lo, Rob T.H., de Kort, Gérard A.P., Bruijnen, Rutger C.G., Dik, Pieter, Horenblas, Simon, and de Kort, Laetitia M.O.

Published
2022

39. Clomiphene citrate for men with hypogonadism: a systematic review and meta-analysis

Author

Urologie Onderzoek, Other research (not in main researchprogram), Urologie Medisch volwassenen, Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, Huijben, Manou, Lock, M. Tycho W.T., de Kemp, Vincent F., de Kort, Laetitia M.O., van Breda, H. M.K., Urologie Onderzoek, Other research (not in main researchprogram), Urologie Medisch volwassenen, Zorgeenheid Urologie Medisch, Child Health, Regenerative Medicine and Stem Cells, Huijben, Manou, Lock, M. Tycho W.T., de Kemp, Vincent F., de Kort, Laetitia M.O., and van Breda, H. M.K.

Published
2022

49. Clomiphene citrate for men with hypogonadism: a systematic review and meta‐analysis.

Author

Huijben, Manou, Lock, M. Tycho W.T., de Kemp, Vincent F., de Kort, Laetitia M.O., and van Breda, H.M.K

Subjects
HYPOGONADISM, CLOMIPHENE, CITRATES, TESTIS physiology, PRECOCIOUS puberty, TREATMENT duration, KALLMANN syndrome
Abstract

Background: Male hypogonadism is a clinical and biochemical androgen insufficiency syndrome, becoming more prevalent with age. Exogenous testosterone is first‐choice therapy, with several side effects, including negative feedback of the hypothalamic–pituitary–gonadal axis, resulting in suppression of intratesticular testosterone production and spermatogenesis. To preserve these testicular functions while treating male hypogonadism, clomiphene citrate is used as off‐label therapy. This systematic review and meta‐analysis aimed to evaluate the effectiveness and safety of clomiphene citrate therapy for men with hypogonadism. Methods: The EMBASE, PubMed, Cochrane databases were searched in May 2021, for effectiveness studies of men with hypogonadism treated with clomiphene citrate. Both intervention and observational studies were included. The Effective Public Health Practice Project Quality Assessment Tool, a validated instrument, was used to assess methodological study quality. The primary outcome measure was the evaluation of serum hormone concentration. Secondary outcomes were symptoms of hypogonadism, metabolic and lipid profile, side effects, safety aspects. Results: We included 19 studies, comprising four randomized controlled trials and 15 observational studies, resulting in 1642 patients. Seventeen studies were included in the meta‐analysis, with a total of 1279 patients. Therapy and follow‐up duration varied between one and a half and 52 months. Total testosterone increased with 2.60 (95% CI 1.82–3.38) during clomiphene citrate treatment. An increase was also seen in free testosterone, luteinizing hormone, follicle stimulating hormone, sex hormone‐binding globulin and estradiol. Different symptom scoring methods were used in the included studies. The most frequently used instrument was the Androgen Deficiency in Aging Males questionnaire, whose improved during treatment. Reported side effects were only prevalent in less than 10% of the study populations and no serious adverse events were reported. Conclusion: Clomiphene citrate is an effective therapy for improving both biochemical as well as clinical symptoms of males suffering from hypogonadism. Clomiphene citrate has few reported side effects and good safety aspects. [ABSTRACT FROM AUTHOR]

Published
2022
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