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2. Keto analogues and amino acid supplementation and its effects on ammonaemia during extenuating endurance exercise in ketogenic diet-fed rats.

Author

Bassini, Adriana, Cameron, L. C., Ferreira, Rogério T., Gonçalves, Sandra C., Coelho, Wagner S., de Magalhães-Neto, Aníbal M., Pedrosa, Maria L., Silva, Marcelo E., and Prado, Eduardo S.

Subjects
AMINO acids, AMMONIA, ANIMAL experimentation, DIETARY supplements, KETOGENIC diet, PHYSICAL fitness, RATS, RESEARCH funding, DATA analysis software, DESCRIPTIVE statistics
Abstract

Keto analogues and amino acids (KAAA) supplementation can reduce blood ammonia concentrations in athletes undergoing high-intensity exercise under both ketogenic and thermoneutral conditions. This study evaluated the acute effects of KAAA supplementation on ammonia metabolism during extenuating endurance exercise in rats fed a ketogenic diet. In all, eighty male Fischer rats at 90 d of age were divided into eight groups, and some were trained using a swimming endurance protocol. A ketogenic diet supplemented with keto analogues was administered for 10 d. Administration of the ketogenic diet ended 3 d before the exhaustion test (extenuating endurance exercise). A ketogenic diet plus KAAA supplementation and extenuating endurance exercise (trained ketogenic diet supplemented with KAAA (TKKa)) increased blood ammonia concentrations by approximately 50 % compared with the control diet (trained control diet supplemented with KAAA (TCKa)) and similar training (effect size=1·33; statistical power=0·50). The KAAA supplementation reduced blood urea concentrations by 4 and 18 % in the control and ketogenic diet groups, respectively, compared with the groups fed the same diets without supplementation. The trained groups had 60 % lower blood urate concentrations after TCKa treatment than after TKKa treatment. Our results suggest that KAAA supplementation can reduce blood ammonia concentrations after extenuating endurance exercise in rats fed a balanced diet but not in rats fed a ketogenic diet. [ABSTRACT FROM AUTHOR]

Published
2018
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3. Hematological parameters in champion of Brazilian jiu-jitsu paradesport: Case study.

Author

Lopes JSS, de Magalhães Neto AM, de Almeida AC, Alves PRL, Silva EL, de Abreu Verli MV, and Andrade CMB

Subjects
Adult, Athletic Performance physiology, Hematologic Tests, Humans, Male, Urinalysis, Martial Arts physiology, Para-Athletes, Physical Conditioning, Human physiology
Abstract

The behavior of biochemical and immunological parameters investigated in the field conditions in athletes is important to influence in the management of recovery and disease prevention as well as, to support the training program, as well as to improve the physical conditioning associated with health and performance. However, for amputee athletes, Brazilian jiu-jitsu paradesport practitioners, there are no published data to date. Thus, the objective of this case study was to quantify the magnitude of biochemical, hematological, and urinary alterations after a simulated fight session in elite athlete with world titles. Outcomes were obtained through blood analysis of samples collected at four different moments (M1-fasting; M2-1.5 hr after caloric intake; M3-Immediately after the simulated fight; M4-24 hr after the simulated fight). Responses triggered by the simulated fight between baseline and after 24 hr were found to increase in monocyte (100%), neutrophil (20%), and insulin (57%) concentrations, while reductions were observed in eosinophils (-50%), lymphocytes (-26.6%), platelets (-22%), cortisol (-50%), and creatine phosphokinase (-45.2%). After 24 hr lactate values returned to baseline levels. The different changes in biochemical and hematological parameters observed constitute responses to acute physical exercise and were according to the level of the high performance athlete. From these data it will be possible to evaluate the periodization, training load, and recovery techniques according to the individual response verified. In addition, these data may be used for comparison purposes within this specific sport, whose literature is still limited., (© 2020 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society.)

Published
2020
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