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Your search keyword '"de Souza, Marcos Romário Matos"' showing total 5 results
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5 results on '"de Souza, Marcos Romário Matos"'

1. Major depression model induced by repeated and intermittent lipopolysaccharide administration: Long-lasting behavioral, neuroimmune and neuroprogressive alterations

Author

Rodrigues, Francisca Taciana Sousa, de Souza, Marcos Romário Matos, Lima, Camila Nayane de Carvalho, da Silva, Francisco Eliclécio Rodrigues, Costa, Deiziane Viana da Silva, dos Santos, Cláudio Costa, Miyajima, Fábio, de Sousa, Francisca Cléa F., Vasconcelos, Silvânia Maria Mendes, Barichello, Tatiana, Quevedo, João, Maes, Michael, de Lucena, David F., and Macedo, Danielle

Published
2018
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2. Evaluation of SARS-CoV-2 ORF7a Deletions from COVID-19-Positive Individuals and Its Impact on Virus Spread in Cell Culture

Author

Simas, Maria Clara da Costa, primary, Costa, Sara Mesquita, additional, Gomes, Priscila da Silva Figueiredo Celestino, additional, Cruz, Nádia Vaez Gonçalves da, additional, Corrêa, Isadora Alonso, additional, de Souza, Marcos Romário Matos, additional, Dornelas-Ribeiro, Marcos, additional, Nogueira, Tatiana Lucia Santos, additional, Santos, Caleb Guedes Miranda dos, additional, Hoffmann, Luísa, additional, Tanuri, Amilcar, additional, Moura-Neto, Rodrigo Soares de, additional, Damaso, Clarissa R., additional, Costa, Luciana Jesus da, additional, and Silva, Rosane, additional

Published
2023
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3. Prolonged SARS-CoV-2 Positivity in Immunocompetent Patients: Virus Isolation, Genomic Integrity, and Transmission Risk

Author

Leitão, Isabela de Carvalho, primary, Calil, Pedro Telles, additional, Galliez, Rafael Mello, additional, Moreira, Filipe Romero Rebello, additional, Mariani, Diana, additional, Castiñeiras, Anna Carla Pinto, additional, da Silva, Gustavo Peixoto Duarte, additional, Maia, Richard Araújo, additional, Corrêa, Isadora Alonso, additional, Monteiro, Fábio Luís Lima, additional, de Souza, Marcos Romário Matos, additional, Gonçalves, Cássia Cristina Alves, additional, Higa, Luiza Mendonça, additional, de Jesus Ribeiro, Liane, additional, Fonseca, Vinicius Wakoff Pereira, additional, Bastos, Victoria Cortes, additional, Voloch, Carolina Moreira, additional, Faffe, Débora Souza, additional, da Costa Ferreira, Orlando, additional, Tanuri, Amilcar, additional, Castiñeiras, Terezinha Marta Pereira Pinto, additional, and da Costa, Luciana Jesus, additional

Published
2021
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4. The interplay between ventro striatal BDNF levels and the effects of valproic acid on the acquisition of ethanol-induced conditioned place preference in mice

Author

dos Santos, Manuel Alves, primary, Escudeiro, Sarah Sousa, additional, Vasconcelos, Germana Silva, additional, Matos, Natália Castelo Branco, additional, de Souza, Marcos Romário Matos, additional, Patrocínio, Manoel Cláudio Azevedo, additional, Dantas, Leonardo Pimentel, additional, Macêdo, Danielle, additional, and Vasconcelos, Silvânia Maria Mendes, additional

Published
2017
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5. The interplay between ventro striatal BDNF levels and the effects of valproic acid on the acquisition of ethanol-induced conditioned place preference in mice.

Author

Júniordos Santos, Manuel Alves, Escudeiro, Sarah Sousa, Vasconcelos, Germana Silva, Matos, Natália Castelo Branco, de Souza, Marcos Romário Matos, Patrocínio, Manoel Cláudio Azevedo, Dantas, Leonardo Pimentel, Macêdo, Danielle, and Vasconcelos, Silvânia Maria Mendes

Subjects
*BRAIN-derived neurotrophic factor, *VALPROIC acid, *ALCOHOLISM, *BRAIN diseases, *CHRONIC diseases
Abstract

Alcohol addiction is a chronic, relapsing and progressive brain disease with serious consequences for health. Compulsive use of alcohol is associated with the capacity to change brain structures involved with the reward pathway, such as ventral striatum. Recent evidence suggests a role of chromatin remodeling in the pathophysiology of alcohol dependence and addictive-like behaviors. In addition, neuroadaptive changes mediated by the brain-derived neurotrophic factor (BDNF) seems to be an interesting pharmacological target for alcoholism treatment. In the present study, we evaluated the effects of the deacetylase inhibitor valproic acid (VPA) (300 mg/kg) on the conditioned rewarding effects of ethanol using conditioned place preference (CPP) (15% v/v; 2 g/kg). Ethanol rewarding effect was investigated using a biased protocol of CPP. BDNF levels were measured in the ventral striatum. Ethanol administration induced CPP. VPA pretreatment did not reduce ethanol-CPP acquisition. VPA pretreatment increased BDNF levels when compared to ethanol induced-CPP. VPA pretreatment increased BDNF levels even in saline conditioned mice. Taken together, our results indicate a modulatory effect of VPA on the BDNF levels in the ventral striatum. Overall, this study brings initial insights into the involvement of neurotrophic mechanisms in the ventral striatum in ethanol-induced addictive-like behavior. [ABSTRACT FROM AUTHOR]

Published
2017
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