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397 results on '"de Vet, Henrica C.W."'

3. Cultural competency of GP trainees and GP trainers: a cross-sectional survey study.

Author

Bouchareb, Siham, van der Heijden, Amber A.W.A, van Diesen, Josine A.Y, van den Muijsenbergh, Maria, Mennink, Sylvia, de Vet, Henrica C.W, Blankenstein, Annette H., and Elders, Petra J.M

Subjects
NATIONAL competency-based educational tests, STATISTICS, HOSPITAL medical staff, PROFESSIONS, CONFIDENCE intervals, FAMILY medicine, ATTITUDES of medical personnel, HEALTH occupations students, CROSS-sectional method, SELF-perception, EMIGRATION & immigration, REGRESSION analysis, T-test (Statistics), CULTURAL competence, QUESTIONNAIRES, DESCRIPTIVE statistics, RESEARCH funding, STUDENT attitudes, STATISTICAL models, DATA analysis, RESIDENTIAL patterns
Abstract

To assess the cultural competence (CC) of GP trainees and GP trainers. Design and setting: A cross-sectional survey study was conducted at the GP Training Institute of Amsterdam UMC. We included 92 GP trainees and 186 GP trainers. We measured the three domains of cultural competency: 1) knowledge, 2) culturally competent attitudes and 3) culturally competent skills. Regression models were used to identify factors associated with levels of CC. Participants rated their self-perceived CC at the beginning and end of the survey, and the correlation between self-perceived and measured CC was assessed. Approximately 94% of the GP trainees and 81% of the GP trainers scored low on knowledge; 45% and 42%, respectively, scored low on culturally competent attitudes. The level of culturally competent skills was moderate (54.3%) or low (48.4%) for most GP trainees and GP trainers. The year of residency and the GP training institute were significantly associated with one or more (sub-)domains of CC in GP trainees. Having >10% migrant patients and experience as a GP trainer were positively associated with one or more (sub-) domains of cultural competence in GP trainers. The correlation between measured and self-perceived CC was positive overall but very weak (Spearman correlation coefficient ranging from −0.1–0.3). The level of cultural competence was low in both groups, especially in the knowledge scores. Cultural competence increased with experience and exposure to an ethnically diverse patient population. Our study highlights the need for cultural competence training in the GP training curricula. General practitioner (GP) trainees find cross-cultural consultations stressful due to a self-perceived lack of cultural competence (CC). The level of CC in general practice is as yet unknown. On average, the level of CC was low for the majority of GP trainees and GP trainers, especially for the scores on knowledge. CC increased with experience and exposure to an ethnically diverse patient population. GP trainees and trainers perceived a lack of covered education on various topics related to the care of migrants. Our study highlights the need for cultural competence training in the GP training curricula. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Baseline radiomics features and MYC rearrangement status predict progression in aggressive B-cell lymphoma

Author

Eertink, Jakoba Johanna, Zwezerijnen, Gerben J.C., Wiegers, Sanne E., Pieplenbosch, Simone, Chamuleau, Martine E.D., Lugtenburg, Pieternella J., de Jong, Daphne, Ylstra, Bauke, Mendeville, Matias, Dührsen, Ulrich, Hanoun, Christine, Hüttmann, Andreas, Richter, Julia, Klapper, Wolfram, Jauw, Yvonne W.S., Hoekstra, Otto S., de Vet, Henrica C.W., Boellaard, Ronald, Zijlstra, Josée M., Radiology and nuclear medicine, Hematology, CCA - Cancer Treatment and quality of life, CCA - Cancer biology and immunology, Pathology, AII - Cancer immunology, CCA - Imaging and biomarkers, Epidemiology and Data Science, APH - Methodology, Amsterdam Neuroscience - Brain Imaging, and AII - Infectious diseases

Subjects
Medizin, Hematology
Abstract

We investigated whether the outcome prediction of patients with aggressive B-cell lymphoma can be improved by combining clinical, molecular genotype, and radiomics features. MYC, BCL2, and BCL6 rearrangements were assessed using fluorescence in situ hybridization. Seventeen radiomics features were extracted from the baseline positron emission tomography–computed tomography of 323 patients, which included maximum standardized uptake value (SUVmax), SUVpeak, SUVmean, metabolic tumor volume (MTV), total lesion glycolysis, and 12 dissemination features pertaining to distance, differences in uptake and volume between lesions, respectively. Logistic regression with backward feature selection was used to predict progression after 2 years. The predictive value of (1) International Prognostic Index (IPI); (2) IPI plus MYC; (3) IPI, MYC, and MTV; (4) radiomics; and (5) MYC plus radiomics models were tested using the cross-validated area under the curve (CV-AUC) and positive predictive values (PPVs). IPI yielded a CV-AUC of 0.65 ± 0.07 with a PPV of 29.6%. The IPI plus MYC model yielded a CV-AUC of 0.68 ± 0.08. IPI, MYC, and MTV yielded a CV-AUC of 0.74 ± 0.08. The highest model performance of the radiomics model was observed for MTV combined with the maximum distance between the largest lesion and another lesion, the maximum difference in SUVpeak between 2 lesions, and the sum of distances between all lesions, yielding an improved CV-AUC of 0.77 ± 0.07. The same radiomics features were retained when adding MYC (CV-AUC, 0.77 ± 0.07). PPV was highest for the MYC plus radiomics model (50.0%) and increased by 20% compared with the IPI (29.6%). Adding radiomics features improved model performance and PPV and can, therefore, aid in identifying poor prognosis patients.

Published
2023

10. An artificial intelligence method using 18F-FDG PET maximum intensity projections to predict 2-year time-to-progression in diffuse large B-cell lymphoma patients

Author

Ferrández, Maria C., primary, Golla, Sandeep S. V., additional, Eertink, Jakoba J., additional, de Vries, Bart M., additional, Lugtenburg, Pieternella. J., additional, Wiegers, Sanne E., additional, Zwezerijnen, Gerben J. C., additional, Pieplenbosch, Simone, additional, Kurch, Lars, additional, Hüttmann, Andreas, additional, Hanoun, Christine, additional, Dührsen, Ulrich, additional, de Vet, Henrica C.W., additional, Zijlstra, Josée M., additional, and Boellaard, Ronald, additional

Published
2023
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17. Discriminative Validity of the Pain Attitudes and Beliefs Scale for Physical Therapists

Author

Eland, Nicolaas D., Kvale, Alice, Ostelo, Raymond W.J.G., De Vet, Henrica C.W., and Strand, Liv I.

Subjects
Physical therapists -- Surveys, Health attitudes -- Surveys, Health surveys -- Evaluation, Pain management -- Surveys, Back pain, Health
Abstract

Background. The Pain Attitudes and Beliefs Scale (PABS) for Physical Therapists aims to measure clinicians' biomedical and biopsychosocial treatment orientations regarding nonspecific low back pain. Objective. The objective of this study was to assess whether the PABS can differentiate between subgroups of physical therapists hypothesized to differ in treatment orientations. Design. This study was a cross-sectional survey. Methods. The PABS was completed by 662 Norwegian physical therapists with a diversity of professional backgrounds. Twenty-four a priori hypotheses on expected differences in PABS scores were formulated. Sufficient discriminative ability was defined as a minimum of 75% confirmed hypotheses. Hypotheses on differences in scores were tested for the biomedical and biopsychosocial subscales separately as well as for combinations of the 2 subscales, representing responders with high biomedical and low biopsychosocial PABS scores and vice versa. Results. Of the 24 hypotheses, only 15 (62.5%) were confirmed. Between-group differences concerning the separate subscales were small, varying from -0.63 to 1.70 scale points, representing values up to 6.0% of the total subscale ranges. Between-group differences were larger when combined subscales were used, varying from 1.80 to 6.70 points, representing values up to 25.1% of the total subscale ranges. Despite little spread in scores, 24% of respondents demonstrated extreme attitudes. Limitations. The lack of convincing scientific evidence from previous research on differences in attitudes and beliefs between physical therapists was a limitation for the formulation of hypotheses. Conclusions. Discriminative validity of separate subscales of the PABS was not supported. Combining the 2 subscales into global treatment attitudes enabled better discrimination. Little spread in biomedical and biopsychosocial orientations explains why more than one-third of the hypotheses were not confirmed. Either Norwegian physical therapists are basically similar in their treatment orientation or the PABS is not able to detect any differences between them., The traditional biomedical view of low back pain (LBP) as a purely structural or biomechanical disorder has been greatly challenged over the past 2 decades. (1,2) There is now a [...]

Published
2019
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23. Physical and Psychological Distress Are Related to Dying Peacefully in Residents With Dementia in Long-Term Care Facilities

Author

Van den Block, Lieve, De Groote, Zeger, Brearley, Sarah, Caraceni, Augusto, Cohen, Joachim, Francke, Anneke, Harding, Richard, Higginson, Irene J., Kaasa, Stein, Linden, Karen, Miccinesi, Guido, Onwuteaka-Philipsen, Bregje, Pardon, Koen, Pasman, Roeline, Pautex, Sophie, Payne, Sheila, LucDeliens, De Roo, Maaike L., Albers, Gwenda, Deliens, Luc, de Vet, Henrica C.W., Francke, Anneke L., and Van Den Noortgate, Nele

Published
2015
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28. External Validation Shows That Baseline PET Radiomics Outperform the IPI Risk Score for Prediction of Outcome in DLBCL

Author

Eertink, Jakoba J, primary, Zwezerijnen, Gerben JC, additional, Heymans, Martijn W, additional, Pieplenbosch, Simone, additional, Wiegers, Sanne E, additional, Dührsen, Ulrich, additional, Hüttmann, Andreas, additional, Kurch, Lars, additional, Hanoun, Christine, additional, Lugtenburg, Pieternella, additional, Barrington, Sally F, additional, Mikhaeel, George, additional, Ceriani, Luca, additional, Zucca, Emanuele, additional, Czibor, Sandor, additional, Györke, Tamás, additional, Chamuleau, Martine E.D., additional, Hoekstra, Otto S, additional, de Vet, Henrica C.W, additional, Boellaard, Ronald, additional, and Zijlstra, Josée M., additional

Published
2022
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30. Proposed New Dynamic Prognostic Index for Diffuse Large B-Cell Lymphoma: International Metabolic Prognostic Index

Author

Mikhaeel, N. George, primary, Heymans, Martijn W., additional, Eertink, Jakoba J., additional, de Vet, Henrica C.W., additional, Boellaard, Ronald, additional, Dührsen, Ulrich, additional, Ceriani, Luca, additional, Schmitz, Christine, additional, Wiegers, Sanne E., additional, Hüttmann, Andreas, additional, Lugtenburg, Pieternella J., additional, Zucca, Emanuele, additional, Zwezerijnen, Gerben J.C., additional, Hoekstra, Otto S., additional, Zijlstra, Josée M., additional, and Barrington, Sally F., additional

Published
2022
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31. STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration. Translation to Russian

Author

Cohen, Jérémie F., primary, Korevaar, Daniël A., additional, Altman, Douglas G., additional, Bruns, David E., additional, Gatsonis, Constantine A., additional, Hooft, Lotty, additional, Irwig, Les, additional, Levine, Deborah, additional, Reitsma, Johannes B., additional, De Vet, Henrica C.W., additional, and Bossuyt, Patrick M.M., additional

Published
2022
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43. Interobserver agreement in automated metabolic tumor volume measurements of Deauville score 4 and 5 lesions at interim 18F-FDG PET in DLBCL

Author

Zwezerijnen, Gerben J.C., Eertink, Jakoba J., Burggraaff, Coreline N., Wiegers, Sanne E., Shaban, Ekhlas A.I.N., Pieplenbosch, Simone, Oprea-Lager, Daniela E., Lugtenburg, Pieternella J., Hoekstra, Otto S., de Vet, Henrica C.W., Zijlstra, Josee M., Boellaard, Ronald, and Hematology

Abstract

Metabolic tumor volume (MTV) on interim-PET (I-PET) is a potential prognostic biomarker for diffuse large B-cell lymphoma (DLBCL). Implementation of MTV on I-PET requires consensus which semi-automated segmentation method delineates lesions most successfully with least user interaction. Methods used for baseline PET are not necessarily optimal for I-PET due to lower lesional standardized uptake values (SUV) at I-PET. Therefore, we aimed to evaluate which method provides the best delineation quality of Deauville-score (DS) 4-5 DLBCL lesions on I-PET at best interobserver agreement on delineation quality and, secondly, to assess the effect of lesional SUVmax on delineation quality and performance agreements. Methods: DS4-5 lesions from 45 I-PET scans were delineated using six semi-automated methods i) SUV 2.5, ii) SUV 4.0, iii) adaptive threshold [A50%peak], iv) 41% of maximum SUV [41%max], v) majority vote including voxels detected by ≥2 methods [MV2] and vi) detected by ≥3 methods [MV3]. Delineation quality per MTV was rated by three independent observers as acceptable or non-acceptable. For each method, observer scores on delineation quality, specific agreements and MTV were assessed for all lesions, and per category of lesional SUVmax (10). Results: In 60 DS4-5 lesions on I-PET, MV3 performed best, with acceptable delineation in 90% of lesions, with a positive agreement (PA) of 93%. Delineation quality scores and agreements per method strongly depended on lesional SUV: the best delineation quality scores were obtained using MV3 in lesions with SUVmax10, were comparable after excluding visually failed MV3 contouring. For lesions with SUVmax

Published
2021

44. Adding psychosocial factors does not improve predictive models for people with spinal pain enough to warrant extensive screening for them at baseline

Author

Ailliet, Luc, Rubinstein, Sidney M., Hoekstra, Trynke, van Tulder, Maurits W., and de Vet, Henrica C.W.

Subjects
Physical therapy -- Patient outcomes, Quality of life -- Psychological aspects -- Health aspects, Health attitudes -- Influence, Health
Abstract

Background. Chiropractors throughout the world by and large focus on patients with musculoskeletal complaints who are generally in good health. Currently, it is widely accepted that neck pain and low back pain are best understood as biopsychosocial phenomena. Objective. The purpose of this study was to determine whether certain psychosocial factors provide added value for predicting recovery. Design. This was a prospective, multicenter, chiropractic, practice-based cohort study in Belgium and the Netherlands. Methods. A total of 917 participants, 326 with neck pain and 591 with low back pain, completed self-administered questionnaires at baseline and at 3, 6, and 12 months. They provided information on several demographic, biomedical, and psychosocial variables. Lasting perceived recovery was used as the outcome measure, that is, recovery at all follow-up assessments from 3 months on. Twenty-seven potential predictors of outcome were used to build the predictive model. Stepwise, backward generalized estimating equation regression models were used to take into account the clustering of participants within practices. For assessment of the added value of psychosocial variables, 2 model fit indexes were compared. Results. After the addition of psychosocial variables, predictors in the final model for neck pain included occupational status, body mass index, duration of complaints, previous treatment, and participant expectations (the model fit was marginally improved from 0.684 to 0.695 for the area under the curve and from 65.0% to 66.1% for the percentage correctly predicted). In the final model for low back pain, the selected predictors included country of treatment, age, duration of complaints, previous imaging, and somatization (the area under the curve changed from 0.669 to 0.715, and the percentage correctly predicted changed from 68.6% to 69.5%). Only a minority of participants had high scores on psychological variables. Limitations. The reliability and validity of lasting recovery as an outcome measure have not been tested. The cohort needs to be seen as a convenience sample. Selection bias, therefore, not be ruled out. There are no indications, however, that patients with complex psychosocial profiles were excluded from this study. Conclusions. Psychosocial variables provided little added value for predicting outcome in people who had neck pain or low back pain and sought chiropractic care. Therefore, chiropractors should not screen extensively for them at baseline. With regard to the identification of the small subgroup of people with high scores on psychosocial variables and a high risk for chronic pain, further investigation is needed., In 1977, Engel highlighted the overall limitations of the traditional biomedical model of disease. (1) Shortly thereafter, Waddell and colleagues (2,3) made an important translation of Engel's idea to the [...]

Published
2016
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48. Combining PET Radiomic Features with MYC Gene Rearrangement Results in High Prediction of Outcome in Diffuse Large B-Cell Lymphoma

Author

Eertink, Jakoba J, primary, Zwezerijnen, Gerben J.C, additional, Wiegers, Sanne E, additional, Chamuleau, Martine E.D, additional, Lugtenburg, Pieternella, additional, De Jong, Daphne, additional, Ylstra, Bauke, additional, Mendeville, Matias, additional, Dührsen, Ulrich, additional, Hüttmann, Andreas, additional, Schmitz, Christine, additional, Richter, Julia, additional, Klapper, Wolfram, additional, Hoekstra, Otto S, additional, de Vet, Henrica C.W, additional, Boellaard, Ronald, additional, and Zijlstra, Josée M, additional

Published
2021
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