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Dry socket or alveolar osteitis is a common postoperative complication following tooth extraction, characterized by severe pain due to the disintegration of the blood clot within the socket. Various factors contribute to its development, such as traumatic extraction, patient age and sex, smoking, and anesthetic use. To mitigate this condition, socket preservation techniques, including the use of bone substitute materials, have been employed. Platelet-rich fibrin (PRF) has emerged as a promising biomaterial, enhancing healing and reducing the incidence of dry socket. Materials and Methods: This systematic review, adhering to the PRISMA guidelines and registered with PROSPERO (ID: CRD 578018), examines the efficacy of PRF in managing dry socket by analyzing studies from PubMed, Scopus, and Web of Science published between January 2013 and May 2024. Boolean keywords have been used in the search strategy: ("Treatment") AND ("Dry Socket") AND ("Platelet Rich Fibrin" OR "PRF"). A total of 738 publications were found using the electronic database search. After the screening phase, 13 records were chosen for qualitative analysis. The results from multiple clinical trials and comparative studies indicate that PRF significantly reduces postoperative pain, expedites healing, and lowers the incidence of Alveolar Osteitis. Despite promising results, further large-scale, randomized studies are needed to validate PRF as a standard treatment for dry socket. [ABSTRACT FROM AUTHOR]

Background: Alveolar osteitis(AO), one of the most common complications occurring in 1–10% of cases following tooth extraction, occurs due to the disruption of clot formation in the extraction socket. This study aims to evaluate the effect of using absorbable gelatin sponge, chlorhexidine gel, and tranexamic acid agents on the development of AO following extraction. Methods: Between March and October 2023, the teeth of 98 healthy patients (average age: 38, range: 19–62) with extraction indications were extracted at Recep Tayyip Erdoğan University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery. 113 extraction sockets(85 molars and 28 premolars) were randomly treated with absorbable gelatin sponge(AGS), chlorhexidine gel with AGS, and tranexamic acid with AGS. Pain and edema levels were recorded using visual analog scale(VAS) ranging from 0 to 10 by the patients. Additionally, presence of halitosis, trismus and exposed bone was noted on forms on 3rd and 7th days (recorded as present or absent). The study prospectively aimed to prevent AO using 3 different dental agents in the extraction sockets. Statistical analyses of the study were conducted using the SPSS software package. Results: Alveolitis was observed in 12 out of 113 tooth extractions(%10.6). Pain and edema scores significantly decreased in absorbable gelatin sponge group on the 7th day (p < 0.05). Pain score on the 7th day in chlorhexidine group and age, edema score on the 7th day in tranexamic acid group, were found to be significantly higher (p < 0.05). Conclusion: Incidence of AO, can be reduced by placing agents in the extraction socket, preventing post-extraction pain experienced by patients. Clinical trials ID: NCT06435832. [ABSTRACT FROM AUTHOR]

Copyright of West China Journal of Stomatology is the property of Sichuan University, West China College of Stomatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Abstract Background Post-tooth extraction, dry socket is a frequently encountered complication, causing substantial pain and hindering the healing process. Conventional approaches to manage this condition have traditionally involved the use of antiseptic dressings to diminish bacterial presence and facilitate healing. This study aims to assess the efficacy of laser therapy in the symptomatic treatment of alveolitis. Methods A literature search was conducted on PubMed, Embase, Scopus, Google Scholar, Web of Science, focusing on publications from 1998 to 31/01/2024 using relevant keywords. The combination of “laser” and “dry socket” was executed through the boolean connection AND. Results At the conclusion of the study, a total of 50 studies were identified across the three search engines, with only three selected for the current systematic study and meta-analysis. The meta-analysis indicated that laser treatment proves effective in addressing alveolitis compared to Alvogyl. However, the correlation between the two was not highly significant. Conclusion These findings suggest that laser therapy may serve as a viable alternative to traditional treatments for dry socket. This minimally invasive procedure has the potential to alleviate pain and promote healing with fewer associated side effects.”

Background: Post-tooth extraction, dry socket is a frequently encountered complication, causing substantial pain and hindering the healing process. Conventional approaches to manage this condition have traditionally involved the use of antiseptic dressings to diminish bacterial presence and facilitate healing. This study aims to assess the efficacy of laser therapy in the symptomatic treatment of alveolitis. Methods: A literature search was conducted on PubMed, Embase, Scopus, Google Scholar, Web of Science, focusing on publications from 1998 to 31/01/2024 using relevant keywords. The combination of "laser" and "dry socket" was executed through the boolean connection AND. Results: At the conclusion of the study, a total of 50 studies were identified across the three search engines, with only three selected for the current systematic study and meta-analysis. The meta-analysis indicated that laser treatment proves effective in addressing alveolitis compared to Alvogyl. However, the correlation between the two was not highly significant. Conclusion: These findings suggest that laser therapy may serve as a viable alternative to traditional treatments for dry socket. This minimally invasive procedure has the potential to alleviate pain and promote healing with fewer associated side effects." [ABSTRACT FROM AUTHOR]

Introduction: Blum defined dry socket as the presence of postoperative pain in and around the extraction site that worsens 1–3 days after the extraction. Methods: 90 female patients seeking extraction of a single tooth in the lower posterior region were divided randomly into 45 patients who received vitamin E inside the socket after extraction (study group) and 45 patients who did not receive vitamin E after extraction (control group). Results: After 3 days, there was a decrease in pain levels in the study group compared to the control group. Only 7 patients out of 45 (16%) suffered from pain compared to 17 patients out of 45 (38%) in the control group. So, the improvement in pain was statistically significant P = 0.02. After 7 days, there was a decrease in wound healing levels in the study group compared to the control group. Only 8 patients out of 45 (17%) had poor wound healing compared to 7 patients out of 45 (16%) in the control group. However, the improvement in wound healing was not statistically significant P = 0.8. Conclusion: Based on the current results, we recommend the use of vitamin E as topical intra-socket medication in reducing the early postoperative pain. [ABSTRACT FROM AUTHOR]

Objectives: The aim of this study was to compare the efficacy and safety of transdermal Fentanyl patch with oral Ketorolac for pain management in dry socket patients. Study design: Sixty patients who were diagnosed with dry socket (VAS > 40 mm) were recruited in this prospective randomized controlled trial. Patients were divided into two groups. Group1 (n = 30) Transdermal Fentanyl patch (25mcg/hr) was given and in Group 2 (n = 30) Ketorolac 10 mg Oral tablet was prescribed for pain management. The primary endpoint was the mean pain scores within 72 h evaluated by visual analog scale (VAS). Secondary measures included the safety and tolerability, amount of rescue medication (analgesic and antiemetic) and effectiveness of treatment interventions by Brief Pain Inventory Questionnaire (BPI). Results: The mean VAS pain scores were significantly less in group 1 (Fentanyl) as compared to group 2 (ketorolac) on all follow-up days. Significant difference was noted in the mean amount of rescue analgesic medication. It was 2.16 + 1.53 in group 1 and 8.50 + 3.98 in group 2. Side effects were seen in both the groups. Nausea (46%) and vomiting (43%) were reported in group 1 while headache (36.6%) and epigastric pain (53.3%) in group 2. Conclusions: Thus, transdermal Fentanyl was better in pain control than Ketorolac with less need for rescue analgesic medication in dry socket. [ABSTRACT FROM AUTHOR]

Aim: Our previous study proposed a technique of inserting gauze coated with oxytetracycline–hydrocortisone ointment into the extraction socket that suppressed the occurrence of dry socket and post‐extraction pain compared with the gauze‐free group. In this study, we estimated the incidence of dry socket and post‐extraction infection in patients with ointment gauze insertion and identified predictors of post‐extraction pain and change in maximum opening volume. Methods: This retrospective study was carried out on patients who underwent lower third molar extraction in the Department of Oral Surgery at a general hospital in Japan. Results: The incidence of dry socket and infection after tooth extraction was 1.05% and 0.35%. The mean visual analog scale (VAS) on the operative day was 4.15; the VAS for postoperative day (POD)1 and POD7 were 2.28 and 0.55, respectively. The percentage change in maximum mouth opening on POD1 was −9.88%, and that on POD7 was −1.51%. Multivariable analysis indicated that age and Winter position classification were predictors of POD1 VAS, and female sex, smoking, and Winter position classification were predictors of POD7 VAS. Winter position classification and preoperative maximum mouth opening, respectively, were identified as predictors of maximum mouth opening percent change on POD1 and POD7. Conclusions: The insertion of gauze coated with oxytetracycline–hydrocortisone ointment into the extraction socket of the mandibular third molar showed a low incidence of dry socket and post‐extraction infection. Moreover, the Winter position classification was suggested to be an independent predictor of postoperative pain and the maximum mouth opening percent change. [ABSTRACT FROM AUTHOR]

Introduction Alveolar osteitis is the most common postoperative complication of tooth extraction. This medical condition has been recognized for decades, however its treatment approach is diverse with varying outcome. Aim of the study The purpose of this review is to examine and discuss contemporary methods of treating dry socket. Through a synthesis of available studies, the paper aims to identify the most beneficial methods to deal with this post-extraction complication. Materials and methods An analysis of scientific articles available in Pubmed and Google Scholar databases was conducted. The study used publications from 2017 to 2024. The search process included the use of the following keywords: “dry socket”, “alveolar osteitis”, “alveolitis sicca dolorosa”, “socket pain treatment”. Results Thirty-five articles were selected and reviewed carefully and independently by all authors. The agents used in the treatment of dry socket were classified as: remedies, drugs and medications, blood products, and technologies. Each group of agents is described with a discussion of their therapeutic efficacy. Summary Dry socket is a common dental problem. Currently, non-invasive methods of treating this complication are preferred. Modern solutions can provide quick and effective therapy. The treatment should relieve discomfort and promote tissue regeneration. Despite various methods, there is still no clear opinion on the best way to treat dry socket.

Background: Alveolar osteitis (AO) or ''dry socket'' affects the quality of life of patients, and there is a high clinical demand for its effective treatment. Objective: To evaluate the effect of Er:YAG laser therapy (ErLT) on AO after mandibular third molar surgery. Methods: Eighty-three patients were randomly divided into Er (n = 43) and control groups (n = 40). In the Er group, the Er:YAG laser (2940 nm; AT Fidelis Fotona, Ljubljana, Slovenia) was used to irradiate the AO site directly in micro short-pulsed mode (pulse duration 0.1 ms, pulse energy 100 mJ, frequency 40 Hz, water 4, and air 2) until all debris and necrotic material had been removed, exposing fresh bone and soft tissue surfaces with blood exudation. The control group received mechanical therapy until the treated lesions resembled those in the Er group. Pain assessment was performed at baseline and on days 1-7 post-intervention using the visual analog scale (VAS). Wound healing was assessed using the wound healing index (WHI). The operating times of the two therapies were also recorded. Results: Group Er had lower VAS scores than the control group on days 1-3 (p = 0.00). There was no significant difference between the two groups on days 4-7 (p = 0.15). The WHI scores were better in the Er group than those in the control group (t = 2.65, p = 0.01), especially in terms of redness (t = 2.70, p = 0.01). There was no significant difference in the operating time between the two groups (t = 0.76, p = 0.45). Conclusions: Compared with mechanical therapy, ErLT for AO provides rapid pain relief and improved wound healing. [ABSTRACT FROM AUTHOR]

Objective: The objective of this paper was to evaluate the rate of post‐operative complications following Oral Surgery procedures at the Eastman Dental Hospital. Dento‐alveolar surgery procedures can lead to complications including pain, swelling, bleeding, infection and numbness amongst others. Although many are considered minor and resolve swiftly, it is important as clinicians to have an understanding of the incidence of complications prior to undertaking surgical treatment to allow evaluation of the risks and benefits. Materials and Methods: Electronic patient records were reviewed across a 3‐month period from February to April 2022 for every patient receiving treatment under local or general anaesthetic and intravenous sedation. Patients returning for an unplanned appointment with a problem related to their treatment was classified as a "post‐operative complication". Information was recorded regarding patient demographics, treatment type and modality, complications, management and outcome. Results were analysed using Microsoft Excel. Results: Nine hundred and ninety four patients received treatment in total. The overall complication rate was 6.33%. The treatment modality with the highest incidence of complications was general anaesthetic. Third molar extractions resulted in the highest proportion of complications out of the procedures considered. The complication with the highest incidence was post‐operative pain and swelling (2%), followed by dry socket (1.5%) and post‐operative infection (1.4%). Conclusion: Post‐operative complications can occur following a range of procedures and can lead to significant morbidity. Clinicians should consider the likelihood of complications occurring when planning treatment as well as early recognition. Future auditing could consider medical co‐morbidities of patients and potential influences of this on developing complications. [ABSTRACT FROM AUTHOR]

Dry socket or alveolar osteitis is a common postoperative complication following tooth extraction, characterized by severe pain due to the disintegration of the blood clot within the socket. Various factors contribute to its development, such as traumatic extraction, patient age and sex, smoking, and anesthetic use. To mitigate this condition, socket preservation techniques, including the use of bone substitute materials, have been employed. Platelet-rich fibrin (PRF) has emerged as a promising biomaterial, enhancing healing and reducing the incidence of dry socket. Materials and Methods: This systematic review, adhering to the PRISMA guidelines and registered with PROSPERO (ID: CRD 578018), examines the efficacy of PRF in managing dry socket by analyzing studies from PubMed, Scopus, and Web of Science published between January 2013 and May 2024. Boolean keywords have been used in the search strategy: (“Treatment”) AND (“Dry Socket”) AND (“Platelet Rich Fibrin” OR “PRF”). A total of 738 publications were found using the electronic database search. After the screening phase, 13 records were chosen for qualitative analysis. The results from multiple clinical trials and comparative studies indicate that PRF significantly reduces postoperative pain, expedites healing, and lowers the incidence of Alveolar Osteitis. Despite promising results, further large-scale, randomized studies are needed to validate PRF as a standard treatment for dry socket.

Clinicians frequently prescribe systemic antibiotics after lower third molar extractions to prevent complications such as surgical site infections and dry socket. A systematic review of randomised clinical trials was conducted to compare the risk of dry socket and surgical site infection after the removal of lower third molars with different prophylactic antibiotics. The occurrence of any antibiotic-related adverse event was also analysed. A pairwise and network meta-analysis was performed to establish direct and indirect comparisons of each outcome variable. Sixteen articles involving 2158 patients (2428 lower third molars) were included, and the following antibiotics were analysed: amoxicillin (with and without clavulanic acid), metronidazole, azithromycin, and clindamycin. Pooled results favoured the use of antibiotics to reduce dry socket and surgical site infection after the removal of a lower third molar, with a number needed to treat of 25 and 18, respectively. Although antibiotic prophylaxis was found to significantly reduce the risk of dry socket and surgical site infection in patients undergoing lower third molar extraction, the number of patients needed to treat was high. Thus, clinicians should evaluate the need to prescribe antibiotics taking into consideration the patient's systemic status and the individual risk of developing a postoperative infection. [ABSTRACT FROM AUTHOR]

Copyright of Avances en Odontoestomatologia is the property of Ediciones Avances SL and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: The aim of the study evaluation 0f tetracycline, tetracycline plus gelatin sponge efficacy in lowering dry socket incidence among patients experienced extraction procedure for mandibular molars compared to control group.. Material and Methods: The sample was divided into three groups each group have 30 patients (34 male and 56 female) : Group A (patients dealt without intra-socket tetracycline) in which only applying figure of 8 suturing and dressing adhesive material for sockets. Group B (patients managed with intra-socket tetracycline alone) in which patients managed after extraction with tetracycline solution, figure of 8 suturing and dressing adhesive material. Group C (patients managed with intra-socket tetracycline plus gelatin sponge complex) in which patients managed after extraction with tetracycline-gelatin sponge vehicle, figure of 8 suturing and adhesive dressing material. Results: Dry socket following extraction was encountered in 4 female patients, with an incidence of 4.4%. Group A reported the highest number. Conclusions: In spite of the limits of this clinical trial, the placement of tetracycline as intra-socket medicament serve in a good choice for treating extracted socket, by reducing bacterial load that will result in lowering the possible chances of infection thus relieving pain, on the other hand the Ora-aid dressing material serve a good way accompanied with suturing in avoiding dry socket occurrence. [ABSTRACT FROM AUTHOR]

Background and Aims: Dry socket is one of the most common post-tooth-extraction complications. The aim of this study was to investigate the relationship between some of the predisposing factors of dry socket and this complication in all maxillary and mandibular molars and evaluation of its incidence. Furthermore, the two jaws were compared. Materials and Methods: In this descriptive-analytical cross-sectional study, 150 patients were examined in 2020 in the city of Zahedan. A questionnaire consisting of two sections was designed: In the first section age, gender, systemic disease, smoking status, contraceptive pill consumption, and antibiotic consumption were investigated. In the second section, data related to the difficulty of surgery based on the duration of surgery and the number of local anesthetic cartridges that were administered were collected. Then, the collected data were analyzed by Chi-square and KruskalWallis tests. Results: The incidence of dry socket was 25.3%. The frequency of dry socket was significantly relevant to smoking, oral contraceptive consumption, difficulty of the surgery, and the number of local anesthetic cartridges that were administered (P≤0.05). Age, gender, controlled systemic disorder, and systemic antibiotic usage for two weeks prior to surgery revealed no significant associations with dry socket (P>0.05). Furthermore, the frequency of dry socket in maxillary and mandibular jaws had a significant difference according to smoking status, difficulty of surgery, and number of local anesthetics carpules (P≤0.05). Conclusion: It is recommended to identify high-risk groups when performing extraction to consider pre-operative and post-operative measures in order to reduce postoperative complication [ABSTRACT FROM AUTHOR]

Background and Aims: Dry socket is one of the most common post-tooth-extraction complications. The aim of this study was to investigate the relationship between some of the predisposing factors of dry socket and this complication in all maxillary and mandibular molars and evaluation of its incidence. Furthermore, the two jaws were compared. Materials and Methods: In this descriptive-analytical cross-sectional study, 150 patients were examined in 2020 in the city of Zahedan. A questionnaire consisting of two sections was designed: In the first section age, gender, systemic disease, smoking status, contraceptive pill consumption, and antibiotic consumption were investigated. In the second section, data related to the difficulty of surgery based on the duration of surgery and the number of local anesthetic cartridges that were administered were collected. Then, the collected data were analyzed by Chi-square and Kruskal-Wallis tests. Results: The incidence of dry socket was 25.3%. The frequency of dry socket was significantly relevant to smoking, oral contraceptive consumption, difficulty of the surgery, and the number of local anesthetic cartridges that were administered (P≤0.05). Age, gender, controlled systemic disorder, and systemic antibiotic usage for two weeks prior to surgery revealed no significant associations with dry socket (P>0.05). Furthermore, the frequency of dry socket in maxillary and mandibular jaws had a significant difference according to smoking status, difficulty of surgery, and number of local anesthetics carpules (P≤0.05). Conclusion: It is recommended to identify high-risk groups when performing extraction to consider pre-operative and post-operative measures in order to reduce postoperative complications.

Objectives: To investigate the efficacy of concentrated growth factors (CGF) and ozone in the treatment of alveolar osteitis (AO). Materials and methods: Patients admitted for the treatment of AO and eligible for the study were included and divided into control, ozone, and CGF + ozone groups. For the treatment of AO alveogyl, ozone, and CGF + ozone were applied to control, ozone, and CGF + ozone groups, respectively, and repeated on 3rd day. Demographic data and oral hygiene were recorded at the initial visit. Pain with visual analog scale (VAS) and analgesic consumption were evaluated at the 6th and 24th h, and on 2nd–7th days. Granulation tissue health and inflammation severity were evaluated on the 1st, 3rd, and 7th days. Quality of life was evaluated with the postoperative symptom severity scale (Posse) on the 7th day. Results: A total of 60 patients (43 females/17 males; mean age 42.7 ± 13.76 years), 20 patients per group were included. Among the groups, pain scores on the 7th day (p = 0.042), granulation tissue health on the 3rd (p = 0.003) and 7th (p = 0.015) days showed a significant difference while analgesic consumption, Posse scores, and inflammation severity showed no significant differences (p > 0.05). Between genders analgesic consumption at 6 h (p = 0.027), 24 h (p = 0.033), and on the 2nd day (p = 0.034) and inflammation severity on the 7th day (p = 0.012) showed significant differences while Posse scores and granulation tissue health showed no significant differences (p > 0.05). Conclusions: This study demonstrates that regenerative treatment which modulates angiogenesis, and tissue regeneration by stimulating stem cells, growth factors, and cytokines with CGF + ozone are more effective than conventional treatment regarding AO. Clinical relevance: Usage of CGF and ozone together provides faster and more satisfactory management of AO. [ABSTRACT FROM AUTHOR]

Abstract Objectives The aim of this study is to evaluate the efficacy between ozone gas and 1% chlorhexidine (CHX) gel in the incidence of dry socket after surgical extraction of impacted lower third molars. Material and Methods Overall, 30 patients of both genders were included in the study, with indication of surgical extraction of lower third molar, positioned similarly after being clinically and radiographically checked by X‐ray and orthopantomography. Each patient was subjected to both groups in separate sessions: treated with ozone gas and with CHX gel 1%. Data on pain intensity, number of taken analgesics‐painkillers, and dry socket were recorded for 48 h and at Day 7. Results Ozone gas and CHX gel effectively reduced pain intensity and prevented dry socket. The number of taken analgesics 48 h and 7 days after surgery showed no statistical significance. The same was observed for the distribution of pain. Only one patient reported the occurrence of dry socket 7 days after the surgical extraction. Conclusions Ozone gas and CHX 1% gel are both efficient in decreasing postoperative symptoms and incidence rates of dry socket, but in comparison to each other, the use of ozone gas is showing a bit better prevention capability.

Aims: This study aimed to clinically evaluate of a novel gelatin-based biodegradable sponge after mandibular posterior teeth extraction to assess its abilities in controlling bleeding, pain, and dry socket compared a commercial sponge. Trial design: In this study, 26 patients who needed the extraction of two mandibular molar teeth were selected and, in each patient, after tooth extraction, the prepared gelatin sponge was used in the test group and the commercial sponge was used in the control group in the form of a randomized, double-blind, split-mouth clinical trial. The sterile gauzes were used on top of each sponge to absorb the extra blood (unabsorbed blood of sponges) to assess the blood absorption amount. Also, the amount of bleeding was recorded for 1 and 4 h after extraction for two groups. The amount of pain was measured for 12, 24, and 48 h after tooth extraction by Visual Analogue Scale (VAS). All patients also returned for examination four days after extraction to assess the occurrence of dry socket. Results: The results showed that the average weight of absorbed blood by sterile gauze in the control group (6.32 ± 1.06 g) was higher than in test group (3.97 ± 1.1 g), e.g., the bleeding control was better for the test group (p < 0.05). Bleeding was observed to be significantly reduced in the test group within 1 h (p = 0.003), within 1–4 h (p = 0.002), and after 4 h (p = 0.042) post-operatively in comparison to the control group. The average pain decreased significantly over time in both groups and the reduction of the pain was significantly higher for the test group (p < 0.05). Just one dry socket case occurred in the control group. Conclusion: The prepared sponge is recommended for use in dental surgeries because of its abilities in bleeding, pain, and dry socket control. [ABSTRACT FROM AUTHOR]

Objectives: The aim of this scoping review was to determine the effectiveness of the platelet-rich fibrin in the control of pain associated with alveolar osteitis. Materials and methods: Reporting was based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Extension for Scoping Reviews. A literature search was conducted in the PubMed and Scopus databases to identify all clinical studies on the application of platelet-rich fibrin in the control of pain caused by alveolar osteitis. Data were extracted independently by two reviewers and qualitatively described. Results: The initial search returned 81 articles, with 49 identified after duplicates removal; of these, 8 were selected according to the inclusion criteria. Three of the eight studies were randomized controlled clinical trials, and four were non-randomized clinical studies, two of which were controlled. One study was case series. In all of these studies, pain control was evaluated using the visual analog scale. Overall, the use of platelet-rich fibrin resulted effective in the control of pain determined by alveolar osteitis. Conclusions: Within the limits of this scoping review, the application of platelet-rich fibrin in the post-extra-extraction alveolus reduced the pain associated with alveolar osteitis in almost all the included studies. Nevertheless, high-quality randomized trials with adequate sample size are warranted to draw firm conclusions. Clinical relevance: Pain associated with alveolar osteitis causes discomfort to the patient and is challenging to be treated. Use of platelet-rich fibrin could be a promising clinical strategy for pain control in alveolar osteitis if its effectiveness will be confirmed by further high-quality studies. [ABSTRACT FROM AUTHOR]

Aim: This study aimed to: (i) calculate personal financial costs associated with urgent dental attendance; and (ii) investigate the pain‐related disability and quality of life impact of dental conditions which result in urgent dental attendance. Methodology: Data were collected from those presenting with urgent dental conditions to an out‐of‐hours dental service, a dental emergency clinic (DEC) and five primary care general dental practices across North‐East England. A pre‐operative questionnaire explored the impact of urgent dental conditions on oral health‐related quality of life (OHRQoL) using Oral Health Impact Profile‐14 (OHIP‐14) and a modified Graded Chronic Pain Scale (GCPS). OHIP‐14 yields a maximum score of 56, with a higher score indicating a lower OHRQoL. Personal financial costs were summed to provide a total. These included travel, appointment fees, childcare costs, medication use and time away from work. Data were analysed using one‐way anova and multivariable modelling. Results: In total, 714 participants were recruited. The mean OHIP‐14 score was 25.73; 95% CI [24.67, 26.79], GCPS CPI was 71.69; 95% CI [70.09, 73.28] and GCPS interference was 49.56; 95% CI [47.24, 51.87]. Symptomatic irreversible pulpitis was the most frequently managed dental emergency and was associated with the highest mean OHIP‐14 score (31.67; 95% CI [30.20, 33.15]). The mean personal financial cost of urgent dental care (UDC) was £85.81; 95% CI [73.29, 98.33]. Differences in travel time (F[2, 691] = 10.24, p <.001), transport costs (F[2, 698] = 4.92, p =.004), and appointment time (F[2, 74] = 9.40, p <.001) were significant between patients attending an out‐of‐hours dental service, DEC and dental practices for emergency care, with a DEC being associated with the highest costs and dental practices the lowest. Conclusions: Diseases of the pulp and associated periapical disease were the most common reason for patients to present for UDC and were the most impactful in terms of OHRQoL and pain in the present sample. Personal financial costs are significant from urgent dental conditions, with centralized services increasing the burden to patients of attending appointments. [ABSTRACT FROM AUTHOR]

Objective: The purpose of the study was to determine if the intra‐alveolar Aloe vera extract powder could reduce the incidence of alveolar osteitis (Dry socket) following extraction in the premolar site. Materials and methods: This trial was a double‐blinded randomized controlled clinical study with a split‐mouth design which included 40 premolars sockets in 20 adult patients, aged 25–49 years. Each patient had two symmetrical extraction sites. The study sample was randomly allocated into two groups (A) the Aloe vera group, and group (B) the control group, extractions were performed for both sides in the same appointment. The occurrence of dry sockets was recorded on the third and seventh days after the extraction. Also, post‐extraction pain scores and the healing of the extraction socket were assessed. Results: The Aloe vera group showed a lower post‐extraction alveolar osteitis (dry socket) occurrence compared with the control group with a statistically significant difference (p < 0.05). The results also showed a decrease in pain scores in the experimental group compared to the control group with statistically significant differences on the first, third and seventh day after extraction (p < 0.05). Also, there were statistically significant differences in the degrees of healing of the extraction socket between the two groups on the seventh day after extraction (p < 0.05). Conclusion: It was concluded that the topical application of Aloe vera extract powder intra‐alveolar after extraction may decrease the incidence of alveolar osteitis (dry socket), improve socket healing and reduce post‐extraction pain. [ABSTRACT FROM AUTHOR]

Objectives: The aim of this study is to evaluate the efficacy between ozone gas and 1% chlorhexidine (CHX) gel in the incidence of dry socket after surgical extraction of impacted lower third molars. Material and Methods: Overall, 30 patients of both genders were included in the study, with indication of surgical extraction of lower third molar, positioned similarly after being clinically and radiographically checked by X-ray and orthopantomography. Each patient was subjected to both groups in separate sessions: treated with ozone gas and with CHX gel 1%. Data on pain intensity, number of taken analgesicspainkillers, and dry socket were recorded for 48 h and at Day 7. Results: Ozone gas and CHX gel effectively reduced pain intensity and prevented dry socket. The number of taken analgesics 48 h and 7 days after surgery showed no statistical significance. The same was observed for the distribution of pain. Only one patient reported the occurrence of dry socket 7 days after the surgical extraction. Conclusions: Ozone gas and CHX 1% gel are both efficient in decreasing postoperative symptoms and incidence rates of dry socket, but in comparison to each other, the use of ozone gas is showing a bit better prevention capability. [ABSTRACT FROM AUTHOR]

Background: Alveolar osteitis (AO) is widely reported as the most common post‐operative complication following surgical and non‐surgical exodontia. Despite being one of the most studied complications in dentistry, there is no established consensus on its aetiology, alongside a relative paucity of studies looking exclusively into AO incidence in children and adolescents. Objectives: To determine the incidence, risk factors and pattern of presentation of AO in children and adolescents following exodontia, as well as identifying concepts and theories to provide a basis regarding why such a common post‐operative complication reportedly manifests so rarely in the paediatric population. Methods: This cross‐sectional analysis forms part of a prospective service evaluation of the exodontia service provided by Newcastle Dental Hospital. All patients aged 5–16 who underwent dental extractions of deciduous and/or permanent teeth under general anaesthetic (GA) between 15 June 2020 and the 15 July 2020 were telephoned 1 week following their procedure to determine if any had developed post‐operative complications. Data were cleaned manually and analysed using descriptive statistics, exploratory analysis with chi‐squared tests and multivariable analyses. A scoping review was performed using the PubMed, OVID Medline and Scopus databases. Results: Four of 150 patients (2.8%) developed AO and reported extreme pain which began 2–3 days after removal, lasted 2 days after onset, and were all associated with the non‐surgical removal of lower first permanent molar teeth. All patients who developed AO were female and aged between 9 and 10 years old. Mandibular sockets were significantly associated with development of AO (p = 0.026). Conclusions: Despite the belief that AO rarely manifests in children, the incidence of paediatric AO in this study is in line with that of AO found in the adult literature. The literature is inconsistent and conflicting regarding current understanding of AO. As far as possible, an atraumatic approach to exodontia should be adopted. We have proposed four underlying concepts which may benefit from future research given the paucity of research exclusively into dry socket in children and adolescents. [ABSTRACT FROM AUTHOR]

Background: Data regarding the quality of online information regarding alveolar osteitis (AO) are lacking. Objective: To assess the quality of online information regarding AO. Materials and Methods: Two search terms ("alveolar osteitis" and "dry socket") were entered separately into three search engines. A qualitative assessment of the websites that satisfied inclusion/exclusion criteria was carried out using the QUality Evaluation Scoring Tool (QUEST), the Journal of the American Medical Association (JAMA) benchmarks, and via the presence of the Health on the Net (HON)code seal. Website readability was evaluated using the Simple Measure of Gobbledygook (SMOG) and Flesch Reading Ease Score tools. Statistical analyses were performed by GraphPad Software® (GraphPad Software Inc., La Jolla, CA, U.S.). Results: Most of the 31 assessed websites were from the United States (41.93%). The mean QUEST score was 14.10 out of a maximum 28 (SD = 4.63; 95% CI: 11.80–16.39). Eight (25.8%) websites scored three or all four JAMA benchmarks and four (12.9%) scored zero. Five (16.12%) displayed the HONcode seal. Higher QUEST scores were recorded for websites that satisfied at least three out of JAMA criteria (p < 0.01; 95% CI: −13.13 to −5.215) and for websites that contained the HONcode seal (p < 0.01; 95% CI: −15.000 to −5.00) compared to those that did not. The mean SMOG readability score was 8.95 (SD: 8.68; 95% CI: 8.46–9.43). Conclusions: The online information regarding AO varies considerably. The readability scores exceed the recommended levels for written health information. The dental profession should consider the development of online resources that address the highlighted shortcomings. [ABSTRACT FROM AUTHOR]

Background. Tooth extraction is the most common surgical intervention in the outpatient practice of a dental surgeon. In most cases, bone wound healing is uncomplicated. However, in some patients the course of healing is complicated by acute inflammatory process of dry socket (alveolar osteitis), the frequency of which increases with increasing trauma of surgery. In dentally healthy patients with typical tooth extraction, dry socket occurs in 2.55%, with difficult – in 9.84%, with atypical extraction of the lower wisdom tooth – in 31.03% of cases. In the presence of diabetes, the incidence of dry socket with typical removal is much higher and according to various authors it is 9.7-13.5%. Objective. The aim of the research was to study the publications and their analysis on the current diagnosis, prevention and treatment of patients with dry socket. Methods. Scientific sources were the articles in world periodicals on dental surgery and therapy, microbiology as well as some electronic resources and patents. Results. At present, many techniques, methods, schemes, compositions for treatment of various forms of dry socket are established. Most often, antibacterial drugs or their combinations with other drugs are used. However, antibacterial drugs do not always have a pronounced anti-inflammatory effect due to the high resistance of the oral microflora. In these cases, contemporary drugs in the form of a composition with long-term antiseptic, anti-inflammatory and analgesic action are rational. Conclusions. The action of a Flupetsal composition, which contains antimicrobial and immunomodulatory drug flurenizide, was clinically proven for treatment of patients with dry socket; the properties of the available ingredients provide a high disinfectant effect, prevent development of inflammation in the tissues and its transition to purulence. A contemporary effective method of treating patients with dry socket is carried out according to the developed method.

Tooth extraction commonly leads to postoperative wound bleeding, bacterial infection, and even the occurrence of dry socket. Therefore, developing a biomedical material with favorable antibacterial and excellent hemostatic properties to prevent the post-extraction dry socket is necessary. Herein, quaternary ammonium chitosan/ carboxymethyl starch/alginate (ACQ) sponges are developed via Ca2+ cross-linking, electrostatic interaction, and lyophilization methods. The results show that the bio-multifunctional sponges exhibit interconnected porous structures with significant fluid absorption rates and suitable water vapor transmission rates. In vitro cellular and hemolysis experiments indicate that the developed sponges have acceptable biocompatibility. Notably, the constructed sponges effectively inhibit the growth of E. coli, S. aureus, and C. albicans, as well as achieve rapid hemostasis in the mouse liver injury and mini-pig tooth extraction models by absorbing blood and promoting red blood cell adhesion. Thus, the created bio-multifunctional sponges show tremendous promise as a hemostatic material for wound management after tooth extraction.

Objective: The main objective of this study was to establish the association between risk factors and complications after oral surgery. Material and Methods: A cohort study was developed between April of 2017 and March of 2018 through a register of patients admitted with buccal surgery indication at the San Borja Arriarán hospital, Chile. Results: The incidence of post-surgical complications was 5.8%, with alveolitis being the most frequent. In the bivariate analysis, surgical difficulty was the only intraoperative variable that presented a significant association with the development of post-surgical complications (p

Background: The present study was conducted for comparing the efficacy of Neocone, Alvogyl and Zinc Oxide Eugenol Packing for the Treatment of Dry Socket. Materials & methods: A total of 60 patients with AO were included and were randomly divided into three study groups as follows:Group 1: Management of dry socket by Alvogyl®, Group 2: Management of dry socket by Zinc Oxide Eugenol (ZOE), and Group 3: Management of dry socket by Neocone®. The socket was irrigated with warm sterile saline solution. Curettage was avoided. Loose debris was removed, taking care to avoid dislodging any residual clot present in the socket. Placement of solution was done according to their respective study groups. Wong Baker Visual Analogue Scale was used for assessment of pain at different time intervals. Clinical examinations for the signs of healing of dry socket were performed. All the results were recorded and analysed using SPSS Software. Results: Mean time for initial pain relief among the patients of group 1, Group 2, Group 3 was 8.36 minutes, 29.5 minutes and 19.4 minutes respectively. While comparing statistically, significant results were obtained. While assessing the effect of different medicaments on healing of dry socket, at third week, signs of dry socket was persistence in 50 percent, 60 percent and 65 percent of the patients of Group 1, group 2 and group 3 respectively. Significant results were obtained while analysing statistically. Conclusion: Alvogyl is superior to the other two medications for providing initial pain relief. [ABSTRACT FROM AUTHOR]

Aim: This prospective study was aimed to evaluate various potential risk factors associated with dry socket in middle aged patients. Materials and Methods: The study included middle aged patients in the age range of 35-50 years. 54 male and 46 female patients were willingly ready to contribute in the study. The relative incidences for dry socket were noticed along with other related risk factors. While recording of the particulars of dry socket, comprehensive evaluation of the extraction was done for each patient. This included thorough case history, method and nature of extraction. All the details and relative information was entered into spreadsheet further investigation. Results: Data was analyzed by statistical analysis software (SPSS). All patients were categorized into 5 age groups. Total 8 patients were in the age group of 35-38 years. 20 subjects were found in the age group of 42-44 years. Maximum 34 subjects were found in the age group of 48-50 years. Total 21 patients found with dry socket in their post operative phase after extraction. P value was highly significant for this. Standard deviation was 0.532 and standard error was 0.930. 4 patients each reported with the history of Tobacco chewing and smoking in various modes. P value was highly significant for this (0.01). Conclusion: Authors concluded that dry socket is a predictable phenomenon after extractions of posterior teeth. Different risk factors are also found to be linked with it including tobacco chewing and smoking and steroid therapy. [ABSTRACT FROM AUTHOR]

To determine the impact of the buccal envelope flap and pedicle design on the post-operative outcome and quality of life following lower third molar surgery (QoL). A randomized case-control clinical study was carried out from September 2017 to September 2019. In this study, a total number of 50 patients with mandibular third molar impaction underwent surgical removal of the same using buccal envelope flap (group A) and pedicle flap (group B). The patients were assessed postoperatively for pain, swelling, trismus, wound dehiscence, dry socket, and quality of life for one month. In terms of pain, swelling, and trismus, there was no statistical difference between the two groups (p > 0.05). However, there was a statistically significant difference found in group B (pedicle flap) in terms of wound dehiscence, dry socket, and quality of life (p < 0.05). The pedicle flap demonstrates fewer incidences of wound dehiscence, dry socket, and a better quality of life when compared to the envelope flap. [Display omitted] [ABSTRACT FROM AUTHOR]

Objectives: Honey has been used for millennia as a treatment for covering wounds that are difficult to repair. Hippocrates already reported the benefits of honey with this type of treatment. The objective of this work is to evaluate the literature on the use of honey in cases as preventive as treatment complications after extractions, more specifically alveolar osteitis or alveolitis. Material and Methods: A systematic literature review was carried out on PubMed, LILACS and Dimensions platforms, following PRISMA guidelines, to gain more knowledge on the topic. Due to the scarcity of articles on the topic, there are no restrictions regarding languages, publication dates or impact factor journal. Animal studies and reviews were excluded. Risk of bias was assessed through Review Manager Software 5.4. Results: With simple, low-cost, and affordable medications, many of the complications after tooth extractions can be resolved more quickly and less painfully for patients with more significant difficulties, whether financial or access, to other treatments. Conclusion: Honey is an effective prevention and treatment for alveolar osteitis. [ABSTRACT FROM AUTHOR]