507 results on '"emerging risk"'
Search Results
2. Brominated Dioxins in Egg, Broiler, and Feed Additives: Significance of Bioassay-Directed Screening for Identification of Emerging Risks in Food.
- Author
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Dirks, Caroline, Gerssen, Arjen, Weide, Yoran, Meijer, Thijs, van der Weg, Guido, van de Schans, Milou G. M., and Bovee, Toine F. H.
- Abstract
Food authorities aim to safeguard our food. This requires sensitive analyses to guarantee detection of both banned and regulated substances at low concentrations. At the same time, broad screening methods are needed to identify new emerging risks. For this purpose, effect-based bioassays combined with mass spectrometric analyses offer an advantage. During the regular monitoring of dioxins in agricultural products, a discrepancy was observed between the results of the DR CALUX (Dioxin-Responsive Chemical Activated Luciferase gene Expression) bioassay and the confirmatory gas chromatographic high resolution mass spectrometric (GC-HRMS) analysis in egg and broiler fat samples. The response in the bioassay was high, suggesting a clear exceedance of the maximum limits of dioxins in these samples, yet regulated dioxins or dl-PCBs were not detected by GC/HRMS analysis. Ultimately, a broad screening analysis using GC-HRMS resulted in the identification of 2,3,7,8-tetrabromo-dibenzofuran (2,3,7,8-TBDF) in both egg and broiler fat. To investigate the potential source of this brominated furan contaminant, different samples were analyzed: bedding material, poultry feed, feed additives (choline chloride and l-lysine), and seaweed. The poultry feed and feed additives all contained 2,3,7,8-TBDF. Using a feed-to-food transfer model, it became clear that the poultry feed was probably the source of 2,3,7,8-TBDF in broilers and eggs through a feed additive like L-lysine or choline chloride. This study underlines the importance of using a combination of effect-based screening assays with sensitive analytical methods to detect potential new and emerging risks. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
3. A Horizon Scan to Support Chemical Pollution–Related Policymaking for Sustainable and Climate‐Resilient Economies.
- Author
-
Green, Christopher, Bilyanska, Antoaneta, Bradley, Mags, Dinsdale, Jason, Hutt, Lorraine, Backhaus, Thomas, Boons, Frank, Bott, David, Collins, Chris, Cornell, Sarah E., Craig, Mark, Depledge, Michael, Diderich, Bob, Fuller, Richard, Galloway, Tamara S., Hutchison, Gary R., Ingrey, Nicola, Johnson, Andrew C., Kupka, Rachael, and Matthiessen, Peter
- Subjects
- *
TECHNOLOGICAL innovations , *POLICY sciences , *ENVIRONMENTAL toxicology , *ENVIRONMENTAL policy , *TEXTILE technology , *TECHNICAL textiles ,DEVELOPED countries - Abstract
While chemicals are vital to modern society through materials, agriculture, textiles, new technology, medicines, and consumer goods, their use is not without risks. Unfortunately, our resources seem inadequate to address the breadth of chemical challenges to the environment and human health. Therefore, it is important we use our intelligence and knowledge wisely to prepare for what lies ahead. The present study used a Delphi‐style approach to horizon‐scan future chemical threats that need to be considered in the setting of chemicals and environmental policy, which involved a multidisciplinary, multisectoral, and multinational panel of 25 scientists and practitioners (mainly from the United Kingdom, Europe, and other industrialized nations) in a three‐stage process. Fifteen issues were shortlisted (from a nominated list of 48), considered by the panel to hold global relevance. The issues span from the need for new chemical manufacturing (including transitioning to non‐fossil‐fuel feedstocks); challenges from novel materials, food imports, landfills, and tire wear; and opportunities from artificial intelligence, greater data transparency, and the weight‐of‐evidence approach. The 15 issues can be divided into three classes: new perspectives on historic but insufficiently appreciated chemicals/issues, new or relatively new products and their associated industries, and thinking through approaches we can use to meet these challenges. Chemicals are one threat among many that influence the environment and human health, and interlinkages with wider issues such as climate change and how we mitigate these were clear in this exercise. The horizon scan highlights the value of thinking broadly and consulting widely, considering systems approaches to ensure that interventions appreciate synergies and avoid harmful trade‐offs in other areas. We recommend further collaboration between researchers, industry, regulators, and policymakers to perform horizon scanning to inform policymaking, to develop our ability to meet these challenges, and especially to extend the approach to consider also concerns from countries with developing economies. Environ Toxicol Chem 2023;42:1212–1228. © 2023 Crown copyright and The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC. This article is published with the permission of the Controller of HMSO and the King's Printer for Scotland. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
4. Emerging risk assessment of areas subject to land subsidence in the southern plain of Tianjin, China.
- Author
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YU Hairuo, GONG Huili, CHEN Beibei, and ZHOU Chaofan
- Subjects
LAND subsidence ,WATER diversion ,SEA level ,TECHNOLOGICAL innovations ,UNDERGROUND areas ,COASTS - Abstract
The development of emerging technologies poses some risks while improving urban construction and human life, thus further causing urban safety problems. Tianjin is a coastal city in China, where the coastal sea level keeps increasing, water cycling is changed by the water supply of the South - to - North Water Diversion Project, and the underground space is subject to development and utilization. These factors, coupled with land subsidence, are all critical for the assessment of emerging risks in Tianjin. This study extracted information on the land subsidence of the southern plain in Tianjin and then predicted the retreat of the natural coastline in Tianjin by combining the sea level rise rate. Accordingly, this study predicted the high - risk factors brought by relative sea level rise in Tianjin using a machine learning method (XGBoost) . In addition, this study analyzed the emerging risks caused by the South - to - North Water Diversion Project and the development and utilization of underground space and revealed the response patterns of the water supply and the construction and operation of subways to the urban safety of Tianjin. The study on the emerging risks brought about by the combination of land subsidence and modern human activities will provide a scientific basis for regional disaster prevention and mitigation and improve cities' ability to resist disasters. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
5. The need for European harmonization of Nutrivigilance in a public health perspective: a comprehensive review.
- Author
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Vo Van Regnault, G., Costa, M. C., Adanić Pajić, A., Bico, A. P., Bischofova, S., Blaznik, U., Menniti-Ippolito, F., Pilegaard, K., Rodrigues, C., and Margaritis, I.
- Abstract
According to the European Union regulation, some countries have established a pre-market notification system for food supplements while others have not. As this regulation is unfulfilled, a notified and marketed food supplement ingredient in one country may be forbidden in another. Even though food supplements shall not be placed on the market if unsafe, some products may still expose the consumers to risks. The risk is increased by easier access due to worldwide dissemination fostered by the internet and free movement of goods in the European Union. The Rapid Alert System for Food and Feed and the Emerging Risks Exchange Network are described. To date, the European Union legislation does not include a provision to establish a dedicated vigilance system for food supplements (Nutrivigilance). Six European Union countries have nevertheless set up national systems, which are presented. The present lack of European Union data collection harmonization, does not allow easy cooperation between countries. This article advocates for creating a coordinated European Nutrivigilance System to detect and scrutinize adverse effects of food supplements. This, to help in directing science-based risk assessments and reinforce the science-based decision of policy makers to improve public health safety. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
6. First Belgian Report of Ertapenem Resistance in an ST11 Klebsiella Pneumoniae Strain Isolated from a Dog Carrying bla SCO-1 and bla DHA-1 Combined with Permeability Defects.
- Author
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Debergh, Hanne, Maex, Margo, Garcia-Graells, Cristina, Boland, Cécile, Saulmont, Marc, Van Hoorde, Koenraad, and Saegerman, Claude
- Subjects
KLEBSIELLA pneumoniae ,ERTAPENEM ,PERMEABILITY ,MICROBIAL sensitivity tests ,POINT defects ,DOGS - Abstract
Klebsiella pneumoniae of sequence type (ST) 11 is a hyper-epidemic nosocomial clone, which is spreading worldwide among humans and emerging in pets. This is the first report, to the best of our knowledge, of multidrug-resistant (MDR) K. pneumoniae ST11 carrying bla
SCO-1 and blaDHA-1 , isolated from a four-month-old dog in Belgium. Antimicrobial susceptibility testing (AST) of the isolate, performed via broth microdilution following the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines, revealed resistance to eight different classes of antimicrobials, including carbapenems, in particular ertapenem, third-generation cephalosporins and fluoroquinolones. A hybrid approach, combining long- and short-read sequencing, was employed for in silico plasmid characterization, multi-locus sequence typing (MLST) and the identification and localization of antimicrobial resistance (AMR) and virulence-associated genes. Three plasmids were reconstructed from the whole-genome sequence (WGS) data: the conjugative IncFIB(K), the non-mobilizable IncR and the mobilizable but unconjugative ColRNAI. The IncFIB(K) plasmid carried the blaSCO-1 gene, whereas IncR carried blaDHA-1 , both alongside several other antimicrobial resistance genes (ARGs). No virulence genes could be detected. Here, we suggest that the resistance to ertapenem associated with susceptibility to imipenem and meropenem in K. pneumoniae could be related to the presence of blaSCO-1 and blaDHA-1 , combined with permeability defects caused by point mutations in an outer membrane porin (OmpK37). The presence of the blaSCO-1 gene on a conjugative IncFIB(K) plasmid is worrisome as it can increase the risk of transmission to humans, to animals and to the environment. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
7. Methodology for probabilistic tsunami-triggered oil spill fire hazard assessment based on Natech cascading disaster modeling
- Author
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00609894, 60874104, 90371476, Nishino, Tomoaki, Miyashita, Takuya, Mori, Nobuhito, 00609894, 60874104, 90371476, Nishino, Tomoaki, Miyashita, Takuya, and Mori, Nobuhito
- Abstract
A novel modeling methodology is presented for cascading disasters triggered by tsunami hazards considering uncertainties. The proposed methodology focuses on tsunami-triggered oil spills and subsequent fires, a type of natural hazard-triggered technological (Natech) event. The methodology numerically simulates the time-varying behavior of tsunami-triggered oil spill fires for numerous stochastically generated scenarios and performs a probabilistic mapping of the maximum radiative heat flux as a quantitative measure of the fire hazard. To enable these assessments, probabilistic tsunami hazard assessments are extended to include the tsunami-induced movement of oil storage tanks, resulting oil spills, tsunami-driven oil fire spread, and thermal radiation from fires. The uncertainty of the earthquake fault slip distribution, oil filling level of storage tanks, and fire starting time and position is incorporated into the new assessments. To demonstrate the methodology, a realistic case study is conducted for a coastal petrochemical industrial park in Japan conditioned on possible offshore moment magnitude 9.1 earthquakes. Contrary to typical tsunami direct impact assessments, the results highlight the cascading effects of tsunamis and large variability in key output variables concerning oil spills and fires. This indicates that the methodology is useful for deepening stakeholders’ understanding of tsunami-triggered cascading disasters and improving risk reduction plans.
- Published
- 2024
8. Emerging Risks in the FinTech Industry – Insights from Data Science and Financial Econometrics Analysis.
- Author
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Morales, Lucía, Gray, Geraldine, and Rajmil, Daniel
- Subjects
FINANCIAL technology ,CORPORATE finance ,DATA science ,GLOBAL Financial Crisis, 2008-2009 ,TIME series analysis - Abstract
The FinTech industry has exhibited very high growth levels since the Global Economic and Financial Crisis of 2008. The sector growth has been accelerated because of the disruption caused by COVID-19 and that derived in the global health crisis, a crisis with significant implications for global economic stability. To examine the risk profile of FinTech firms, the CRISP-DM methodology was followed to aid in the implementation of clustering and classification algorithms, combined with time series regression models. This research paper offers insights on financial risk assessment by combining machine learning techniques and traditional econometric modeling to acknowledge challenges associated with the analysis of time series in the financial context and framed in the US FinTech sector. The main findings revealed a lack of significant differences between the FinTech and Non- FinTech firms in the US stock market. The results were surprising as the FinTech sector’s speed of development and fast changes in financial innovation have led to the emergence of significant risks that do not seem to be captured by the examined market and firm-specific data sets. The research outcomes point to a substantial vacuum on the regulatory framework at both national and international levels to ensure efficient FinTech governance and adequate industry development amid very ambitious growing prospects. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
9. Managing Emerging Risks in Strategic Scenarios of Uncertainty and Complexity: A Theoretical Framework
- Author
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Cavatorta, Liliana, Rosso, Gianluca, Poli, Roberto, Editor-in-Chief, and Valerio, Marco, editor
- Published
- 2019
- Full Text
- View/download PDF
10. From Risk to Legislative Innovation: The Trajectory of Marine Submersion Through the French Media.
- Author
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Lelaurain, Solveig, Guignard, Séverin, Schleyer-Lindenmann, Alexandra, and Bertoldo, Raquel
- Subjects
ELECTRONIC newspapers ,SHIFT registers ,CONTENT analysis - Abstract
Storm Xynthia (2010) brought to the fore marine submersion as a great concern to French authorities and communities. This storm illustrates how a single major event can have long-lasting effects on climate risk management. To discern this effect, we conduct two studies analyzing the emergence and evolution of concerns related to marine submersion in French national and regional newspapers prior to and after the storm (2005–2018). In Study 1, we examine trends in issue coverage and how "marine submersion" was appropriated by French media discourse over the selected period, identifying and segmenting specific topical sequences. In Study 2, a computer-assisted content analysis of 260 articles highlights a dichotomy of themes before and after Storm Xynthia. Articles published prior to Xynthia (2005–2009) warned of marine submersion among the expected impacts of climate change. Those published just after Xynthia (2010–2013) present highly structured and technical descriptions of national risk management policies. In recent years (2014–2018), articles focus on local stakeholders' challenge to national risk management policies, described as too far removed from local dynamics. Our studies reveal the emergence and amplification, via public debate in French newspaper media, of "marine submersion" as a hazard, and the objectification of the risk through Storm Xynthia. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
11. Conceptual Classification of Leading Indicators for the Dynamic Analysis of Emerging Risks in Integrated Management Systems.
- Author
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Brocal Fernandez, Francisco, Sanchez-Lite, Alberto, Fuentes-Bargues, José Luis, Sebastian, Miguel Á., and González-Gaya, Cristina
- Subjects
ECONOMIC indicators ,RISK assessment ,MANUFACTURING processes ,CLASSIFICATION - Abstract
Companies that implement Integrated Management Systems (IMS) require approaches that optimize resources and results. In the case of IMS of a new or emerging nature, the use of dynamics risk analysis approaches and the integration of real-time monitoring data in the risk assessment process offers news perspectives. The objective of this work is to identify and classify leading indicators that facilitate the dynamic analyses of emerging risks in an IMS for quality, environment, and safety. For it, such indicator analysis has been based on a bibliographic analysis. Regarding results, firstly, a structure of indicators emerges configured of three categories organized in two levels. At the first level, it is established by the indicators of the IMS which can be integrated. The second level is configured of two categories of interrelated indicators, that is, process integrity indicators and occupational risks indicators. In turn, each of these three categories has two dimensions. The first dimension represents the direction of the indicator, leading or lagging indicator. The second dimension represents the risk nature, emerging or traditional risk. Secondly, a classification of the leading indicators is derived according to the categories of the indicators and the risk nature. This classification shows the direction of the leading indicators as well as qualitative graduation of the potential associated consequences. Said theoretical framework has been applied to a case study configured by a manufacturing process. Thus, a conceptual scheme has been developed that represents the first step towards a more in-depth and detailed development that allows the identification and definition of specific leading indicators within an IMS from a dynamic and emerging risk perspective. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
12. At the Boundary of Risk and Uncertainty: Behavioral Insights Into Enterprise Risk Management
- Author
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Gletsu, C. David
- Subjects
- Business Administration, Management, Accounting, Behaviorial Sciences, enterprise risk management (ERM), sensemaking, construal level, framing, social identity, numeracy, risk quantification, emerging risk
- Abstract
This dissertation investigates how managers assess ambiguous emerging exposures which lie at the intersection of measurable risk and unmeasurable uncertainty. The problem is important because it has implications for organizational resilience and the efficiency and effectiveness of the risk management function. Study 1, a qualitative interview-based exploration, suggests that risk managers assessing emerging risks in the insurance industry may not evaluate front-line business managers as critically as the “Three Lines” risk governance model recommends they should. The data indicate four potential reasons for the seeming reluctance: (1) the effect of framing emerging risks as opportunities; (2) shared social identity among risk managers and business unit managers; (3) preferences for measuring ambiguous risks qualitatively instead of quantitatively; and (4) the time horizon within which a risk is expected to materialize.Study 2, an experiment with 115 financial professionals, examines two of these reasons: shared social identity and risk framing. It finds that risk managers who identify more strongly with the business units they assess tend to be less objective and that positively framed risks are evaluated less critically. Study 3, an experiment with 193 risk managers, investigates the remaining two reasons—risk quantification and time horizon—and the influence of a risk manager’s numerical ability. The study tests how these factors affect the assessment of ambiguous risks indirectly through subjective processing fluency and perceived reliability of risk information. Results show significant indirect effects of information presentation format on willingness to challenge risk information, moderated by time horizon and numeracy. Specifically, controlling for numeracy, risk managers who are considering the distant future along with a quantitative presentation experience greater difficulty processing the risk information, which they then perceive as less reliable. Additionally, controlling for time horizon, less numerate risk managers show more skepticism toward quantitative data and more confidence in qualitative data.This research responds to calls for more behavioral studies in enterprise risk management and contributes practical insights into the perceptions and performance of risk professionals.
- Published
- 2024
13. Application of risk management plan to technical risks in metro construction: Case study of the Grand Paris Express project.
- Author
-
Zhang, Yi
- Subjects
- *
INSURANCE policies , *CONTRACT management , *ENVIRONMENTAL risk - Abstract
• The Risk Management Plan (RMP) is presented; • Its application to the technical risks in the Grand Paris Express project is illustrated; • A balanced risk allocation with contractual system and insurance is highlighted; • The RMP benefits in overcoming some challenges of underground works are demonstrated. This article presents the application of Risk Management Plan (RMP) to technical risks in metro construction. The RMP defines a balanced risk allocation between client, designer and contractor, and outlines technical and financial solutions in the occurrence of doubted events. It is an iterative process, and an approach of continuous improvement from design phase to construction phase, and aims to identify potential hazards, quantify relative risks, and implement adequate preventive measures and mitigations to avoid and reduce risks whilst identifying what actions are to be taken if risks occur. After the RMP presentation, a case study of the Grand Paris Express (GPE) project is then introduced in the French context. The GPE project is the largest metro project underway in Europe, comprised of 68 new metro stations and 200 km of additional tracks. It is located in an urban area with high technical risks. Throughout this case study, examples of how the RMP was applied to the technical risks such as geological and geotechnical risk, damage risk to neighbouring structures or assets and environmental risk are provided. The major identified risks are analysed with preventive measures, sometimes already integrated in the design, and technical solutions retained for the construction, as well as mitigation measures. In addition, the management of new risks that appeared during construction is presented, with a specific example involving the use of steel fibre-reinforced concrete tunnel segments. Finally, the contract management and insurance to accompany the RMP application in risk management are also covered. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
14. Managing emerging environmental risks when we do not know enough about them: The case of respirable mineral dust.
- Author
-
Liu, Wen, Salmond, Jennifer, Allen, Kristiann, and Tadaki, Marc
- Subjects
MINERAL dusts ,ASBESTOS ,ENVIRONMENTAL risk ,AIR pollution ,ENVIRONMENTAL management ,SILICA - Abstract
Although the management of emerging environmental risks has received more attention recently, planning and public policy scholars have not yet generated consensus on management approaches for environmental and occupational risks that remain poorly described, unquantified, and may be potentially 'unknowable'. Our case study focuses on exposure to respirable mineral dust (RMD), a specific category of particulate air pollution which includes examples such as respirable crystalline silica and asbestos fibres, as an example of a risk that is emerging and that has often 'escaped' regulations in many countries. This article (i) reviews prevailing risk management strategies and (ii) discusses their limitations when applied to the unique characteristics of RMD. The aim of the paper is to examine the suitability of existing risk management approaches for the evaluation of emerging environmental risks, which are bounded by significant uncertainties in quantifying the likelihood of the occurrence and/or severity of the hazard. We identify potential improvements to these strategies, highlighting the value of different protection levels, strategies, measures, and proactive actions which are enabled within an adaptive management framework that responds more nimbly to future changes. • Synthesised the challenges of managing respirable mineral dust. • Seven risk management approaches are most useful for different risk characteristics. • Identified improvements to these strategies for emerging environmental risks. • Potential improvements of strategies that respond more nimbly to future changes. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
15. A Horizon Scan to Support Chemical Pollution–Related Policymaking for Sustainable and Climate‐Resilient Economies
- Author
-
Christopher Green, Antoaneta Bilyanska, Mags Bradley, Jason Dinsdale, Lorraine Hutt, Thomas Backhaus, Frank Boons, David Bott, Chris Collins, Sarah E. Cornell, Mark Craig, Michael Depledge, Bob Diderich, Richard Fuller, Tamara S. Galloway, Gary R. Hutchison, Nicola Ingrey, Andrew C. Johnson, Rachael Kupka, Peter Matthiessen, Robin Oliver, Stewart Owen, Susan Owens, John Pickett, Sam Robinson, Kerry Sims, Pete Smith, John P. Sumpter, Svetlana Tretsiakova‐McNally, Mengjiao Wang, Tom Welton, Katherine J. Willis, Iseult Lynch, Johnson, Andrew C [0000-0003-1570-3764], Sims, Kerry [0000-0001-6273-4083], Lynch, Iseult [0000-0003-4250-4584], and Apollo - University of Cambridge Repository
- Subjects
Early warning ,early warning ,Chemical pollution ,Chemicals management ,Health, Toxicology and Mutagenesis ,chemical pollution ,chemicals management ,Agriculture ,Ecotoxicology ,sustainable chemicals ,Sustainable chemicals ,Europe ,climate change ,biodiversity loss ,Artificial Intelligence ,Biodiversity loss ,Climate change ,Emerging risk ,Horizon scanning ,Humans ,Environmental Chemistry ,emerging risk ,Environmental Pollution ,horizon scanning - Abstract
Data Availability Statement: All data are included in the Supporting Information for publication online. Supporting Information is available online at https://setac.onlinelibrary.wiley.com/doi/10.1002/etc.5620#support-information-section . Copyright © 2023 Crown copyright and The Authors. While chemicals are vital to modern society through materials, agriculture, textiles, new technology, medicines, and consumer goods, their use is not without risks. Unfortunately, our resources seem inadequate to address the breadth of chemical challenges to the environment and human health. Therefore, it is important we use our intelligence and knowledge wisely to prepare for what lies ahead. The present study used a Delphi-style approach to horizon-scan future chemical threats that need to be considered in the setting of chemicals and environmental policy, which involved a multidisciplinary, multisectoral, and multinational panel of 25 scientists and practitioners (mainly from the United Kingdom, Europe, and other industrialized nations) in a three-stage process. Fifteen issues were shortlisted (from a nominated list of 48), considered by the panel to hold global relevance. The issues span from the need for new chemical manufacturing (including transitioning to non-fossil-fuel feedstocks); challenges from novel materials, food imports, landfills, and tire wear; and opportunities from artificial intelligence, greater data transparency, and the weight-of-evidence approach. The 15 issues can be divided into three classes: new perspectives on historic but insufficiently appreciated chemicals/issues, new or relatively new products and their associated industries, and thinking through approaches we can use to meet these challenges. Chemicals are one threat among many that influence the environment and human health, and interlinkages with wider issues such as climate change and how we mitigate these were clear in this exercise. The horizon scan highlights the value of thinking broadly and consulting widely, considering systems approaches to ensure that interventions appreciate synergies and avoid harmful trade-offs in other areas. We recommend further collaboration between researchers, industry, regulators, and policymakers to perform horizon scanning to inform policymaking, to develop our ability to meet these challenges, and especially to extend the approach to consider also concerns from countries with developing economies. Environ Toxicol Chem 2023;00:1–17. © 2023 Crown copyright and The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC. This article is published with the permission of the Controller of HMSO and the King's Printer for Scotland. Department for Environment, Food and Rural Affairs
- Published
- 2023
16. The Public's Risk Information Seeking and Avoidance in China During Early Stages of the COVID-19 Outbreak
- Author
-
Mei Liu, You Chen, Dan Shi, and Tingwu Yan
- Subjects
information seeking ,information avoidance ,COVID-19 ,emerging risk ,risk perception ,Psychology ,BF1-990 - Abstract
This study uses the Planned Risk Information Seeking Model (PRISM) to estimate the public's information seeking and avoidance intentions during the COVID-19 outbreak based on an online sample of 1031 Chinese adults and provides support for the applicability of PRISM framework in the situation of a novel high-level risk. The results indicate that information seeking is primarily directed by informational subjective norms (ISN) and perceived seeking control (PSC), while the main predictors of information avoidance include ISN and attitude toward seeking. Because ISN are the strongest predictor of both information seeking and avoidance, the way the public copes with COVID-19 information may be strongly affected by individuals' social environment. Furthermore, a significant relationship between risk perception and affective risk response is identified. Our results also indicate that people who perceive greater knowledge of COVID-19 are more likely to report greater knowledge insufficiency, which results in less information avoidance.
- Published
- 2021
- Full Text
- View/download PDF
17. The Public's Risk Information Seeking and Avoidance in China During Early Stages of the COVID-19 Outbreak.
- Author
-
Liu, Mei, Chen, You, Shi, Dan, and Yan, Tingwu
- Subjects
COVID-19 pandemic ,RISK perception ,COVID-19 ,INFORMATION modeling - Abstract
This study uses the Planned Risk Information Seeking Model (PRISM) to estimate the public's information seeking and avoidance intentions during the COVID-19 outbreak based on an online sample of 1031 Chinese adults and provides support for the applicability of PRISM framework in the situation of a novel high-level risk. The results indicate that information seeking is primarily directed by informational subjective norms (ISN) and perceived seeking control (PSC), while the main predictors of information avoidance include ISN and attitude toward seeking. Because ISN are the strongest predictor of both information seeking and avoidance, the way the public copes with COVID-19 information may be strongly affected by individuals' social environment. Furthermore, a significant relationship between risk perception and affective risk response is identified. Our results also indicate that people who perceive greater knowledge of COVID-19 are more likely to report greater knowledge insufficiency, which results in less information avoidance. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
18. Analysis of Metrological Requirements in Occupational Health and Safety Regulations Related to the Emerging Risk of Exposure to Vibrations.
- Author
-
Lorente-Pedreille, Raquel María, Brocal, Francisco, Saenz-Nuño, María A., and Sebastián, Miguel A.
- Subjects
INDUSTRIAL hygiene ,REQUIREMENTS engineering ,SAFETY regulations ,CRITICAL analysis ,RISK assessment ,UNCERTAINTY - Abstract
In occupational exposure to vibration, the risk assessment process is defined through a regulatory framework that presents some relevant metrological problems. This framework considers methods based on estimation and on measurements. Estimation methods could employ existing information that is provided for each manufacturer to each individual tool or application to carry out such estimation. The use of estimation methods has some problems, such as substantial uncertainty. When using measurement methods, some metrological aspects are not fully defined. Therefore, a new and emerging risk appears due to certain methodologic limitations. Consequently, the variation between the estimated and the actual values could overestimate the level of occupational exposure to vibrations. Thus, with this paper, a critical analysis of this emerging metrological problem is provided. For this, a critical analysis of the metrological requirements regarding European standards is developed. To this end, the estimation method and measure method are investigated, considering, in both cases, the main factors related to uncertainty, reliability, and traceability. With this structure, a set of metrological limitations have been identified, thus pointing towards future lines of research that allow the improvement of the process of assessing the level of occupational exposure to vibrations. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
19. Understanding Risk Information Seeking and Processing during an Infectious Disease Outbreak: The Case of Zika Virus.
- Author
-
Hubner, Austin Y. and Hovick, Shelly R.
- Subjects
ZIKA virus ,COMMUNICABLE diseases ,INFORMATION processing ,MATERNAL age ,DISEASE outbreaks - Abstract
This study draws on the Planned Risk Information Seeking Model (PRISM) to assess Zika virus information seeking and systematic processing, paying particular attention to the relationship between perceived knowledge and knowledge insufficiency. Novel risks, such as Zika, provide an interesting context for examining whether information‐seeking models, such as PRISM, are able to predict information seeking when available information is limited or scarce. A cross‐sectional, online study of men and women of childbearing age (N = 494) residing in the state of Florida was conducted. Our results provide some support for the PRISM for predicting Zika information seeking intention, as well as systematic processing of information. We also found that individuals with high levels of perceived knowledge were more likely to report high level of knowledge insufficiency, illustrating that contextual factors may impact the fit of risk information seeking models. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
20. HTLV-1 infection: An emerging risk. Pathogenesis, epidemiology, diagnosis and associated diseases.
- Author
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Eusebio-Ponce, Emiliana, Anguita, Eduardo, Paulino-Ramirez, Robert, and Javier Candel, Francisco
- Subjects
HTLV-I ,EPIDEMIOLOGY ,CARCINOGENESIS ,T cells ,VERTICAL transmission (Communicable diseases) - Abstract
Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
21. Brain-computer interfaces in safety and security fields: Risks and applications
- Author
-
Universidad de Alicante. Departamento de Física, Ingeniería de Sistemas y Teoría de la Señal, Universidad de Alicante. Instituto Universitario de Física Aplicada a las Ciencias y las Tecnologías, Brocal, Francisco, Universidad de Alicante. Departamento de Física, Ingeniería de Sistemas y Teoría de la Señal, Universidad de Alicante. Instituto Universitario de Física Aplicada a las Ciencias y las Tecnologías, and Brocal, Francisco
- Abstract
With the recent increasing interest of researchers for Brain-Computer Interface (BCI), emerges a challenge for safety and security fields. Thus, the general objective of this research is to explore, from an engineering perspective, the trends and main research needs on the risks and applications of BCIs in safety and security fields. In addition, the specific objective is to explore the BCIs as an emerging risk. The method used consists of the sequential application of two phases. The first phase is carried out a scoping literature review. And with the second phase, the BCIs are analyzed as an emerging risk. With the first phase, thematic categories are analyzed. The categories are fatigue detection, safety control, and risk identification within the safety field. And within the security field are the categories cyberattacks and authentication. As a result, a trend is identified that considers the BCI as a source of risk and as a technology for risk prevention. Also, another trend based on the definitions and concepts of safety and security applied to BCIs is identified. Thus, “BCI safety” and “BCI security” are defined. The second phase proposes a general emerging risk framing of the BCI technology based on the qualitative results of type, level, and management strategies for emerging risk. These results define a framework for studying the safety and security of BCIs. In addition, there are two challenges. Firstly, to design techniques to assess the BCI risks. Secondly, probably more critical, to define the tolerability criteria of individual and social risk.
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- 2023
22. Methodology for probabilistic tsunami-triggered oil spill fire hazard assessment based on Natech cascading disaster modeling.
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Nishino, Tomoaki, Miyashita, Takuya, and Mori, Nobuhito
- Abstract
• A comprehensive method for assessing tsunami-related Natech hazards is proposed. • The method is based on models for tsunami, triggered oil spill and subsequent fire. • The method quantifies fire hazards probabilistically via Monte Carlo simulations. • Uncertainty in tsunami source, tank oil filling and fire ignition is incorporated. • The application is illustrated focusing on possible offshore Mw 9.1 earthquakes. A novel modeling methodology is presented for cascading disasters triggered by tsunami hazards considering uncertainties. The proposed methodology focuses on tsunami-triggered oil spills and subsequent fires, a type of natural hazard-triggered technological (Natech) event. The methodology numerically simulates the time-varying behavior of tsunami-triggered oil spill fires for numerous stochastically generated scenarios and performs a probabilistic mapping of the maximum radiative heat flux as a quantitative measure of the fire hazard. To enable these assessments, probabilistic tsunami hazard assessments are extended to include the tsunami-induced movement of oil storage tanks, resulting oil spills, tsunami-driven oil fire spread, and thermal radiation from fires. The uncertainty of the earthquake fault slip distribution, oil filling level of storage tanks, and fire starting time and position is incorporated into the new assessments. To demonstrate the methodology, a realistic case study is conducted for a coastal petrochemical industrial park in Japan conditioned on possible offshore moment magnitude 9.1 earthquakes. Contrary to typical tsunami direct impact assessments, the results highlight the cascading effects of tsunamis and large variability in key output variables concerning oil spills and fires. This indicates that the methodology is useful for deepening stakeholders' understanding of tsunami-triggered cascading disasters and improving risk reduction plans. [ABSTRACT FROM AUTHOR]
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- 2024
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23. Conceptual Classification of Leading Indicators for the Dynamic Analysis of Emerging Risks in Integrated Management Systems
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Francisco Brocal Fernandez, Alberto Sanchez-Lite, José Luis Fuentes-Bargues, Miguel Á. Sebastian, and Cristina González-Gaya
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dynamics risk analysis ,emerging risk ,integrated management systems ,leading indicators ,safety ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Companies that implement Integrated Management Systems (IMS) require approaches that optimize resources and results. In the case of IMS of a new or emerging nature, the use of dynamics risk analysis approaches and the integration of real-time monitoring data in the risk assessment process offers news perspectives. The objective of this work is to identify and classify leading indicators that facilitate the dynamic analyses of emerging risks in an IMS for quality, environment, and safety. For it, such indicator analysis has been based on a bibliographic analysis. Regarding results, firstly, a structure of indicators emerges configured of three categories organized in two levels. At the first level, it is established by the indicators of the IMS which can be integrated. The second level is configured of two categories of interrelated indicators, that is, process integrity indicators and occupational risks indicators. In turn, each of these three categories has two dimensions. The first dimension represents the direction of the indicator, leading or lagging indicator. The second dimension represents the risk nature, emerging or traditional risk. Secondly, a classification of the leading indicators is derived according to the categories of the indicators and the risk nature. This classification shows the direction of the leading indicators as well as qualitative graduation of the potential associated consequences. Said theoretical framework has been applied to a case study configured by a manufacturing process. Thus, a conceptual scheme has been developed that represents the first step towards a more in-depth and detailed development that allows the identification and definition of specific leading indicators within an IMS from a dynamic and emerging risk perspective.
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- 2021
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24. Addressing Climate Change as an Emerging Risk to Infrastructure Systems.
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Shortridge, Julie and Camp, Janey Smith
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CLIMATE change ,INFRASTRUCTURE (Economics) ,RISK assessment ,URBANIZATION ,PROBABILITY density function - Abstract
The consequences that climate change could have on infrastructure systems are potentially severe but highly uncertain. This should make risk analysis a natural framework for climate adaptation in infrastructure systems. However, many aspects of climate change, such as weak background knowledge and societal controversy, make it an emerging risk where traditional approaches for risk assessment and management cannot be confidently employed. A number of research developments aimed at addressing these issues have emerged in recent years, such as the development of probabilistic climate projections, climate services, and robust decision frameworks. However, additional research is needed to improve the suitability of these methods for infrastructure planning. In this perspective, we outline some of the challenges in addressing climate change risks to infrastructure and summarize new developments aimed at meeting these challenges. We end by highlighting needs for future research, many of which could be well‐served by expertise within the risk analysis community. [ABSTRACT FROM AUTHOR]
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- 2019
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25. Uptake and accumulation of emerging contaminants in soil and plant treated with wastewater under real-world environmental conditions in the Al Hayer area (Saudi Arabia).
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Picó, Yolanda, Alvarez-Ruiz, Rodrigo, Alfarhan, Ahmed H., El-Sheikh, Mohamed A., Alobaid, Samy M., and Barceló, Damià
- Abstract
Abstract In arid and semi-arid areas the use of treated wastewater for crop irrigation and other agricultural practices, such as the use of pesticides, increase the number of emerging contaminants (ECs) in crops. Hazards of these practices to human being are largely unknown since there are few studies yet covering a short range of compounds and most of them under non-realistic conditions. This study aims at assessing this problem that will become global soon in an area of Saudi Arabia heavily affected by the reuse of treated wastewater and pesticide in order to ascertain its scale. The novelty of the study relays in the large number of ECs covered and the variety of crops (cabbage, barley, green beans, eggplants, chili, tomato and zucchini) analysed. Extraction procedure developed provided an appropriate extraction yield (up to 50% of the compounds were recovered within a 70–120% range), with good repeatability (relative standard deviations below 20% in most cases) and sensitivity (LOQ < 25 ng g−1) for the model compounds. Determination by liquid chromatography quadrupole time-of-flight (LC-QqTOF-MS) is able to identify >2000 contaminants. Sixty-four ECs were identified in wastewater but of the sixty-four compounds, six pharmaceuticals (atenolol, caffeine, carbamazepine and its metabolites 10,11-epoxycarbamazepine, gemfibrozil, and naproxen) and seven pesticides (acetamiprid, atrazine deethyl, azoxystrobin, bupirimate, diazinon, malathion, pirimicarb and some of their metabolites) were detected in plants. Furhermore, one metabolite of the ibuprofen (not detected in water or soil), the ibuprofen hexoside was also found in plants. Up to our knowledge, this study demonstrate for the first time the accumulation of ECs in crops irrigated with treated wastewater under real non-controlled environmental conditions. Graphical abstract Unlabelled Image Highlights • Sensitive LC-QqTOF-MS method successfully identify 64 contaminants in water. • Method's performance verified for 40 compounds in two matrices (cabbage and barley) • Presence of 18 pesticides, pharmaceuticals and/or degradation products in plants verified • Crops present more ECs (7) than soil (5) and at higher concentrations [ABSTRACT FROM AUTHOR]
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- 2019
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26. A consequences-based approach for the selection of relevant accident scenarios in emerging technologies.
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Casson Moreno, Valeria, Garbetti, Anna Laura, Leveneur, Sébastien, and Antonioni, Giacomo
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WORK-related injuries , *INDUSTRIAL safety , *RISK assessment , *BIOMASS production , *FACTORY safety - Abstract
Highlights • Innovative biotechnologies are posing emerging risks. • Emerging risks in biorefining processes are often unrecognized or poorly understood. • A risk-based approach can help to address correctly safety issues related to biorefineries. Abstract The rapid progress of innovative biorefinery technologies raises the issue of emerging risk and major accident hazard in biorefineries, as process safety aspects of such technologies are not developing at the same pace with respect to their dissemination and scale-up. To address such problem, in the present work a consequence-based approach was integrated in the framework of a consolidated QRA methodology (ARAMIS), formerly developed in the context of Seveso Directive in the process industries (mainly oil&gas). Among all the possible scenarios identified using ARAMIS, Relevant Accident Scenarios (RAS) were selected by calculating hazard distances using threshold values for the evaluation of damages on human target derived from existing regulations on the control of major accident hazards. The method has been described and used to quantify the risk associated to a biorefinery process: the conversion of lignocellulosic biomass materials to levulinic acid and gamma-valerolactone, where the use of hazardous substances and severe process conditions are required. Using the proposed approach allowed to reduce the number of scenarios to be retained for further analysis. The RAS resulted 1/3 of the scenarios initially identified, simplifying the rest of the risk assessment procedure. The integrated methodology enabled to depict a risk figure for the plant analysed which is not over-conservative, being beneficial during the risk management phase, when risk reduction measures have to be selected and implemented in order to achieve risk tolerance. [ABSTRACT FROM AUTHOR]
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- 2019
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27. Emerging risk in the construction industry: Recommendations for managing exposure to nanomaterials
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Beatriz María Díaz-Soler, María Dolores Martínez-Aires, and Mónica López-Alonso
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emerging risk ,safety risks ,health risk ,engineering controls ,organizational measures ,personal protection equipment. ,Technology ,Mining engineering. Metallurgy ,TN1-997 - Abstract
Nanotechnology has aroused great interest in the construction industry because new materials with outstanding properties are being designed, and the features of traditional materials can be improved. However, exposure to nanomaterials is the most recent new emerging risk in the construction industry and the current knowledge about this topic is limited. This paper aims to identify the main aspects regarding the exposure to and use of nanomaterials in the construction sector from a risk prevention perspective. This starting point allows authors to establish a set of recommendations structured in order to identify how and where to act in order to manage the risk of exposure to nanomaterial on construction sites.
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- 2016
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28. Brain-computer interfaces in safety and security fields: Risks and applications
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F. Brocal, Universidad de Alicante. Departamento de Física, Ingeniería de Sistemas y Teoría de la Señal, Universidad de Alicante. Instituto Universitario de Física Aplicada a las Ciencias y las Tecnologías, and Acústica Aplicada
- Subjects
Risk ,Brain-computer interface ,Public Health, Environmental and Occupational Health ,Security ,Emerging risk ,Building and Construction ,Safety ,Safety, Risk, Reliability and Quality ,Safety Research ,Occupational - Abstract
With the recent increasing interest of researchers for Brain-Computer Interface (BCI), emerges a challenge for safety and security fields. Thus, the general objective of this research is to explore, from an engineering perspective, the trends and main research needs on the risks and applications of BCIs in safety and security fields. In addition, the specific objective is to explore the BCIs as an emerging risk. The method used consists of the sequential application of two phases. The first phase is carried out a scoping literature review. And with the second phase, the BCIs are analyzed as an emerging risk. With the first phase, thematic categories are analyzed. The categories are fatigue detection, safety control, and risk identification within the safety field. And within the security field are the categories cyberattacks and authentication. As a result, a trend is identified that considers the BCI as a source of risk and as a technology for risk prevention. Also, another trend based on the definitions and concepts of safety and security applied to BCIs is identified. Thus, “BCI safety” and “BCI security” are defined. The second phase proposes a general emerging risk framing of the BCI technology based on the qualitative results of type, level, and management strategies for emerging risk. These results define a framework for studying the safety and security of BCIs. In addition, there are two challenges. Firstly, to design techniques to assess the BCI risks. Secondly, probably more critical, to define the tolerability criteria of individual and social risk.
- Published
- 2023
29. Analysis of Metrological Requirements in Occupational Health and Safety Regulations Related to the Emerging Risk of Exposure to Vibrations
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Raquel María Lorente-Pedreille, Francisco Brocal, María A. Saenz-Nuño, and Miguel A. Sebastián
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vibration ,metrology ,emerging risk ,occupational health ,regulation ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
In occupational exposure to vibration, the risk assessment process is defined through a regulatory framework that presents some relevant metrological problems. This framework considers methods based on estimation and on measurements. Estimation methods could employ existing information that is provided for each manufacturer to each individual tool or application to carry out such estimation. The use of estimation methods has some problems, such as substantial uncertainty. When using measurement methods, some metrological aspects are not fully defined. Therefore, a new and emerging risk appears due to certain methodologic limitations. Consequently, the variation between the estimated and the actual values could overestimate the level of occupational exposure to vibrations. Thus, with this paper, a critical analysis of this emerging metrological problem is provided. For this, a critical analysis of the metrological requirements regarding European standards is developed. To this end, the estimation method and measure method are investigated, considering, in both cases, the main factors related to uncertainty, reliability, and traceability. With this structure, a set of metrological limitations have been identified, thus pointing towards future lines of research that allow the improvement of the process of assessing the level of occupational exposure to vibrations.
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- 2020
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30. Responding to the risk of reducing resources: Development of a framework for future change programmes in Environmental Health Services.
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Plume, Ruth, Page, Alan, and Garelick, Hemda
- Abstract
Abstract Environmental Health services in the UK have been subject to significant resource reduction over the last 5 years. It is suggested that services risk becoming unsustainable unless efficient and effective ways of working are employed. With this in mind this paper presents the findings of research into the experience of practitioners who are developing and delivering evolving Environmental Health services in English local authorities in the context of deep cutting budget reductions. The research explores the experience of change and identifies lessons learnt in the development and execution of new models of Environmental Health service delivery to mitigate against risks of unsustainable or undeliverable services. Interviews were carried out with the participants to capture their experience of change and the impact on service delivery. A range of service delivery models have been examined including outsourcing, shared services, regional delivery models and discussion of mutual arrangements and at various stages of development from planning through to full transformation. Field work was undertaken between 2014 and 2016. Thematic analysis of interview transcripts has identified six emergent themes of the experience of change: managing changes effectively; understanding the reasons for change; understanding the nature of Environmental Health; meaningful consultation; viability of the proposal; planning and timeliness. Environmental Health services undergoing transformation may benefit from taking into account the lessons learnt by organisations that have previously undergone significant change in their response to the risk of a reducing resource. [ABSTRACT FROM AUTHOR]
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- 2018
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31. Toxic invasive pufferfish (Tetraodontidae family) along Italian coasts: Assessment of an emerging public health risk.
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Guardone, Lisa, Maneschi, Andrea, Guidi, Alessandra, Armani, Andrea, Gasperetti, Laura, Ricci, Enrica, and Susini, Francesca
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PUFFERS (Fish) , *PUBLIC health , *OCEAN bottom , *PATHOGENIC microorganisms , *INTRODUCED species , *NEUROTOXIC agents , *TISSUES - Abstract
Several pufferfish species belonging to the Tetraodontidae family are currently present in the Mediterranean Sea. Since 2013 Lagocephalus sceleratus is increasingly reported also along Italian coasts, where other two species of less concern, Lagocephalus lagocephalus and Sphoeroides pachygaster , have also occured since a long time. This study represents one of the first attempts to sistematically describe the occurrence in the Mediterranean, and in particular along Italian coasts, of the three aforesaid species, in order to characterize an emerging public health hazard. Reports were searched in scientific articles and dedicated online databases. The following data were collected: number of specimens and type of record, geographical location and date of report, fish size, depth and type of seabed. Overall, at least 111079 individuals of the three species were found in the Mediterranean Sea, including 110237 specimens of L. sceleratus (since 2003), 126 of L. lagocephalus (1878–2017) and 716 of S. pachygaster (1979–2017). The evident differences confirm the invasive character of the toxic Lessepsian immigrant L. sceleratus , the species of main public health concern. Despite this species was recorded along Italian coasts in low numbers (0.08% of the total individuals of L. sceleratus ) and its current distribution is limited to southern regions, the picture could change rapidly. Moreover, the collected data show that most L. sceleratus specimens have a large size and are mainly caught by commercial fishing gears. These factors may increase the risk of this species entering the seafood chain with serious consequences for consumers’ health. Results suggest that the presence of L. sceleratus should be strictly monitored. Institutional measures should be implemented to inform people as regards a new hazard that has the potential to affect the Italian seafood chain. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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32. Drivers of existing and emerging food safety risks: Expert opinion regarding multiple impacts.
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Kendall, Helen, Kaptan, Gulbanu, Stewart, Gavin, Grainger, Matthew, Kuznesof, Sharron, Naughton, Paul, Clark, Beth, Hubbard, Carmen, Raley, Marian, Marvin, Hans J.P., and Frewer, Lynn J.
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FOOD safety , *ENVIRONMENTAL impact analysis , *FOOD supply , *WATER security , *SOCIOECONOMICS , *BIOPHYSICS - Abstract
Considerable research effort is invested in the development of evidence to help policy makers and industry deal with the challenges associated with existing and emerging food safety threats. This research aimed to elicit expert views regarding the relationship between the drivers of existing and emerging food safety risks, in order to facilitate their control and mitigation, and to provide the basis for further international policy integration. A Delphi approach involving repeated polling of n = 106 global food safety experts was adopted. The primary drivers of existing and emerging food safety risks were identified to be demographic change, economic driving forces, resource shortages, environmental driving forces, increased complexity of the food supply chain, water security and malevolent activities . The identification of socio-economic and biophysical drivers emphasises the need for a transdisciplinary and systems approach to food safety management and mitigation. The mitigation of hazards on a case-by-case basis is unlikely to have a major impact on food safety hazards but may have unintended effects (where positive or negative) across a broad spectrum of food safety issues. Rather a holistic or systems approach is required which can address both the intended and unintended effects of different drivers and their interactions. [ABSTRACT FROM AUTHOR]
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- 2018
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33. Growth in the Perception of Cyber Risk: Evidence from U.S. P&C Insurers.
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Pooser, David M., Browne, Mark J., and Arkhangelska, Oleksandra
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RISK assessment ,INSURANCE companies ,PROPERTY ,BUSINESS ,INVESTMENTS - Abstract
The perception of cyber risk has increased in the economy and especially in insurance firms. Using data from publicly traded U.S. property-casualty (P&C) insurers, we examine the trend in cyber risk identification from 2006 to 2015, as well as firms’ characteristics related to cyber risk perception. Roughly one-quarter of our sample identified cyber risk as a material risk factor in 2006, and this group of our sample grew to include substantially all insurers by 2013. The firms that were “early adopters” of cyber risk identification tend to be the smaller, more highly leveraged and higher growth firms. These firms are also more concentrated in their line of business portfolio and use less external reinsurance. This evidence may suggest that the early identifiers of cyber risk were the most sensitive to potential disruption based on their size or firm risk. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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34. A spatial evaluation of global wildfire-water risks to human and natural systems.
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Robinne, François-Nicolas, Bladon, Kevin D., Miller, Carol, Parisien, Marc-André, Mathieu, Jérôme, and Flannigan, Mike D.
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WILDFIRE prevention , *FRESHWATER ecology , *DRINKING water , *WATERSHED management , *WATER supply - Abstract
The large mediatic coverage of recent massive wildfires across the world has emphasized the vulnerability of freshwater resources. The extensive hydrogeomorphic effects from a wildfire can impair the ability of watersheds to provide safe drinking water to downstream communities and high-quality water to maintain riverine ecosystem health. Safeguarding water use for human activities and ecosystems is required for sustainable development; however, no global assessment of wildfire impacts on water supply is currently available. Here, we provide the first global evaluation of wildfire risks to water security, in the form of a spatially explicit index. We adapted the Driving forces-Pressure-State-Impact-Response risk analysis framework to select a comprehensive set of indicators of fire activity and water availability, which we then aggregated to a single index of wildfire-water risk using a simple additive weighted model. Our results show that water security in many regions of the world is potentially vulnerable, regardless of socio-economic status. However, in developing countries, a critical component of the risk is the lack of socio-economic capability to respond to disasters. Our work highlights the importance of addressing wildfire-induced risks in the development of water security policies; the geographic differences in the components of the overall risk could help adapting those policies to different regional contexts. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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35. Small Dense Low-Density Lipoprotein for Risk Prediction of Acute Coronary Syndrome
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Wahid Ali, Abhishek Singh, Rajendra Puhan, Rishi Sethi, and Akshyaya Pradhan
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Coronary angiography ,medicine.medical_specialty ,Acute coronary syndrome ,Emerging risk ,business.industry ,Elevated low-density lipoprotein ,Anterior Descending Coronary Artery ,medicine.disease ,Coronary artery disease ,chemistry.chemical_compound ,chemistry ,Left anterior descending coronary artery ,Internal medicine ,Low-density lipoprotein ,medicine ,Cardiology ,Original Article ,Risk factor ,Major adverse cardiac events ,Cardiology and Cardiovascular Medicine ,business ,Small density low-density lipoprotein - Abstract
Background: Elevated Low density Lipoprotein (LDL) levels have been traditionally associated with development of atherosclerotic coronary artery disease (CAD). As LDL-cholesterol levels are not always raised in acute coronary syndrome (ACS) patients, sd-LDL is an emerging risk factor. The purpose of the present study was tri-fold. Firstly, it aimed to investigate the association of sd-LDL as a risk factor in ACS patients. Secondly, it aimed to correlate the presence of sd-LDL with severity of coronary artery disease as determined by coronary angiography. Lastly, it aimed to correlate the presence of sd-LDL with short-term outcomes. Methods: This was a prospective, hospital-based, cross-sectional, case-control study conducted over a 1-year study duration. Patients above the age of 18 years diagnosed with ACS within 24 h of admission were studied. Blood samples were collected after all patients had undergone coronary angiography and sd-LDL levels were measured. Results: ACS patients had significantly higher sd-LDL levels than non-ACS patients (16.10 ± 1.42 mg/dL vs. 12.67 ± 0.71 mg/dL, P = 0.036). Males had significantly higher sd-LDL levels than females (16.79 ± 1.55 mg/dl vs. 10.77 ± 2.62 mg/dl, P=0.047). Patients with non-left anterior descending coronary artery (LAD) involvement had significantly higher sd-LDL levels compared to patients with LAD involvement (21.92 ± 3.55 mg/dL vs. 14.03 ± 1.35 mg/dL, P = 0.007). Conclusion: These results suggest that sd-LDL is a risk factor for the development of ACS in an Indian population. Cardiol Res. 2021;12(4):251-257 doi: https://doi.org/10.14740/cr1254
- Published
- 2021
36. Pulmonary mucormycosis in post-pulmonary tuberculosis as an emerging risk factor: A rare case report
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Divya Khanduja and Naveen Pandhi
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Pediatrics ,medicine.medical_specialty ,Emerging risk ,business.industry ,Pulmonary tuberculosis ,Rare case ,Medicine ,Pulmonary mucormycosis ,business - Abstract
Pulmonary mucormycosis is an uncommon pulmonary fungal disease, which is commonly seen in immunocompromised individuals. It is caused by fungi of class Zygomycetes. It constitutes the third most common invasive fungal infection following aspergillosis and candidiasis. Risk factors include patients with hematological malignancies, diabetes mellitus, and immunocompromised states. It is difficult to diagnose early due to non-specific clinical presentation and delay in treatment associated with greater mortality. As we know that Tuberculosis and HIV are highly prevalent in country like India. Post pulmonary tuberculosis is emerging as a risk factor for Pulmonary mucormycosis in the developing countries like India. Patients with non-resolving pneumonia are generally misdiagnosed as Pulmonary tuberculosis. The diagnosis of Pulmonary Mucormycosis is based upon demonstration of fungal hyphae in the clinical specimen. We highlight the importance of clinical suspicion in these cases for early diagnosis and early treatment initiation can reverse morbidity and mortality associated with Pulmonary Mucormycosis. We report 2 cases of Pulmonary mucormycosis present in post-pulmonary tuberculosis patients.
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- 2021
37. La responsabilité sociale des institutions financières
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Coggins, Frank, Fall, Moussa, Coggins, Frank, and Fall, Moussa
- Abstract
Cette thèse est constituée de trois articles qui s’articulent autour de la RSIF. Le premier article a d’abord pour objectif de comparer les notations extrafinancières des institutions financières (IFs) à celles des entreprises non financières (ENF), pour ensuite vérifier si les notations des banques coïncident avec celles de leur portefeuille de prêts. Pour ce faire, une analyse comparative des notations extrafinancières des IFs et celles des ENF, révèle que les IFs performent mieux que les ENF. Les tests de Friedman indiquent par ailleurs que les notations extrafinancières des banques sont indépendantes de celles de leur portefeuille de prêts. Le test de Kendall confirme également que la performance extrafinancière des banques a une faible concordance avec celle de leur portefeuille de prêts sur 10 des 18 années étudiées en ESG et en Environnement, 6 des 18 années étudiées en Social et 5 des 18 années étudiées en Gouvernance. En d’autres termes, la performance extrafinancière des IFs ne semble pas tenir compte des entreprises qu’elles financent, suggérant notamment que les portefeuilles de prêts des banques ne sont pas suffisamment pris en compte dans les notations des banques. Le deuxième article propose la création d’un indice composite de mesure de la RSIF. Les indicateurs identifiés pour la construction de l’indice découlent de la théorie de l’intermédiation financière, de la théorie des parties prenantes et de la théorie de l’intérêt commun pour retracer les activités des IFs, déterminer les parties prenantes des IFs, leurs attentes et intérêts ainsi que les sources d’externalités négatives. Les données utilisées sont sélectionnées sur la base de leur validité analytique, leur mesurabilité et leur couverture par les IFs de l’échantillon. Le test de fiabilité confirme la cohérence entre les mesures identifiées et l’indice. La robustesse et la sensibilité des variables utilisées sont validées par les indices de sensibilité de Sobol et les coefficients de corréla, This thesis consists of three articles that are structured around the RSIF. The first article aims to compare the extra-financial ratings of financial institutions (FIs) with those of non-financial companies (NFCs), and then to verify whether the ratings of banks coincide with those of their loan portfolio. To this end, a comparative analysis of the extrafinancial ratings of FIs and NFEs reveals that FIs perform better than NFEs. Friedman's tests also indicate that banks' non-financial ratings are independent of their loan portfolio. Kendall's test also confirms that banks' extra-financial performance has a low concordance with that of their loan portfolio over 10 of the 18 years studied in ESG and Environment, 6 of the 18 years studied in Social and 5 of the 18 years studied in Governance. In other words, the extra-financial performance of FIs does not seem to take into account the companies they finance, suggesting in particular that the banks' loan portfolios are not sufficiently taken into account in the banks' ratings. The second article proposes the creation of a composite index to measure SRFI that integrates the specificities of FIs. The indicators used in the construction of the index are derived from financial intermediation theory, stakeholder theory and common interest theory to trace the activities of FIs, determine the stakeholders of FIs, their expectations and interests, and the sources of externalities. Data are selected based on their analytical validity, measurability, and coverage. Reliability testing confirms consistency for the economic, legal, ethical, and SRFI measures, so that measurement error has little impact on the total SRFI index score. The robustness and sensitivity of the variables used are validated by the Sobol indices and correlation coefficients. The proposed arrow plot to aggregate the scores of the three dimensions adequately meets the need and objectives of index decomposition and granular analysis to guide decision
- Published
- 2022
38. Automated food safety early warning system in the dairy supply chain using machine learning
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Liu, Ningjing, Bouzembrak, Yamine, van den Bulk, Leonieke M., Gavai, Anand, van den Heuvel, Lukas J., Marvin, Hans J.P., Liu, Ningjing, Bouzembrak, Yamine, van den Bulk, Leonieke M., Gavai, Anand, van den Heuvel, Lukas J., and Marvin, Hans J.P.
- Abstract
Traditionally, early warning systems for food safety are based on monitoring targeted food safety hazards. Optimal early warning systems, however, should identify signals that precede the development of a food safety risk. Moreover, such signals could be identified in factors from domains adjacent to the food supply chain, so-called drivers of change and other indicators. In this study, we show for the first time that such drivers and indicators may indeed represent signals that precede the detection of a food safety risk. The dairy supply chain in Europe was used as an application case. Using dynamic unsupervised anomaly detection models, anomalies were detected in indicator data expected by domain experts to impact the development of food safety risks in milk. Additionally, a Bayesian network was used to identify the chemical food safety hazards in milk associated with an anomaly for the Netherlands. The results showed that the frequency of anomalies varied per country and indicator. However, all countries showed in the period investigated (2008–2019), anomalies in the indicators “raw milk price” and “barely milk price” and no anomalies in the indicator” income of dairy farms”. A cross-correlation analysis of the number of Rapid Alert for Food and Feed (RASFF) notifications and anomalies in indicators revealed significant correlations of many indicators but difference between countries was observed. Interesting, for all countries the cross corelation with indicator “milk price” was significant, albeit the lag time varied from 5 months (United Kingdom) to 22 months (Italy). This finding suggests that severe changes in domains adjacent to the food supply chain may trigger the development of food safety problems that become visible many months later. Awareness of such relationships will provide the opportunity for food producers or inspectors to take timely measures to prevent food safety problems.
- Published
- 2022
39. Nonalcoholic Fatty Liver Disease: An Emerging Driver of Cardiac Arrhythmia
- Author
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Xiao-Jing Zhang, Jingjing Cai, Haomiao Li, Ze Chen, Hongliang Li, Zhibing Lu, Zhi-Gang She, Feng Zhou, and Jiayi Liu
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Physiology ,Emerging risk ,030204 cardiovascular system & hematology ,Sudden cardiac death ,03 medical and health sciences ,0302 clinical medicine ,Cardiac Conduction System Disease ,Non-alcoholic Fatty Liver Disease ,Risk Factors ,Cardiac conduction defects ,Internal medicine ,Atrial Fibrillation ,Nonalcoholic fatty liver disease ,Prevalence ,medicine ,Humans ,cardiovascular diseases ,Risk factor ,Metabolic disease ,Inflammation ,Ventricular Remodeling ,business.industry ,nutritional and metabolic diseases ,Cardiac arrhythmia ,Arrhythmias, Cardiac ,Atrial fibrillation ,medicine.disease ,digestive system diseases ,Oxidative Stress ,030104 developmental biology ,Adipose Tissue ,Disease Progression ,cardiovascular system ,Cardiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Cardiac arrhythmias and the resulting sudden cardiac death are significant cardiovascular complications that continue to impose a heavy burden on patients and society. An emerging body of evidence indicates that nonalcoholic fatty liver disease (NAFLD) is closely associated with the risk of cardiac arrhythmias, independent of other conventional cardiometabolic comorbidities. Although most studies focus on the relationship between NAFLD and atrial fibrillation, associations with ventricular arrhythmias and cardiac conduction defects have also been reported. Mechanistic investigations suggest that a number of NAFLD-related pathophysiological alterations may potentially elicit structural, electrical, and autonomic remodeling in the heart, contributing to arrhythmogenic substrates in the heart. NAFLD is now the most common liver and metabolic disease in the world. However, the upsurge in the prevalence of NAFLD as an emerging risk factor for cardiac arrhythmias has received little attention. In this review, we summarize the clinical evidence and putative pathophysiological mechanisms for the emerging roles of NAFLD in cardiac arrhythmias, with the purpose of highlighting the notion that NAFLD may serve as an independent risk factor and a potential driving force in the development and progression of cardiac arrhythmias.
- Published
- 2021
40. The changing landscape of atherosclerosis
- Author
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Peter Libby
- Subjects
Emerging risk ,Disease ,030204 cardiovascular system & hematology ,medicine.disease_cause ,Bioinformatics ,Models, Biological ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Risk Factors ,medicine ,Animals ,Humans ,030212 general & internal medicine ,Microbiome ,Risk factor ,Inflammation ,Multidisciplinary ,business.industry ,Cholesterol ,Altered behaviour ,Atherosclerosis ,Vulnerable plaque ,Plaque, Atherosclerotic ,chemistry ,Disease Susceptibility ,business ,Lipoprotein - Abstract
Emerging evidence has spurred a considerable evolution of concepts relating to atherosclerosis, and has called into question many previous notions. Here I review this evidence, and discuss its implications for understanding of atherosclerosis. The risk of developing atherosclerosis is no longer concentrated in Western countries, and it is instead involved in the majority of deaths worldwide. Atherosclerosis now affects younger people, and more women and individuals from a diverse range of ethnic backgrounds, than was formerly the case. The risk factor profile has shifted as levels of low-density lipoprotein (LDL) cholesterol, blood pressure and smoking have decreased. Recent research has challenged the protective effects of high-density lipoprotein, and now focuses on triglyceride-rich lipoproteins in addition to low-density lipoprotein as causal in atherosclerosis. Non-traditional drivers of atherosclerosis—such as disturbed sleep, physical inactivity, the microbiome, air pollution and environmental stress—have also gained attention. Inflammatory pathways and leukocytes link traditional and emerging risk factors alike to the altered behaviour of arterial wall cells. Probing the pathogenesis of atherosclerosis has highlighted the role of the bone marrow: somatic mutations in stem cells can cause clonal haematopoiesis, which represents a previously unrecognized but common and potent age-related contributor to the risk of developing cardiovascular disease. Characterizations of the mechanisms that underpin thrombotic complications of atherosclerosis have evolved beyond the ‘vulnerable plaque’ concept. These advances in our understanding of the biology of atherosclerosis have opened avenues to therapeutic interventions that promise to improve the prevention and treatment of now-ubiquitous atherosclerotic diseases. This Review discusses recent research that has transformed our understanding of the biology of atherosclerosis, and examines its implications for the treatment of atherosclerotic cardiovascular disease.
- Published
- 2021
41. Theoretical framework for the new and emerging occupational risk modeling and its monitoring through technology lifecycle of industrial processes.
- Author
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Brocal, F., Sebastián, M.A., and González, C.
- Subjects
- *
INDUSTRIAL safety , *INNOVATIONS in business , *SOCIAL responsibility of business , *TECHNOLOGICAL innovations - Abstract
Besides traditional occupational risks (TR), industrial processes can generate other risks described by the European Agency for Safety and Health at Work (EU-OSHA) as “new and emerging risks” (NER). The basic definition of NER is that of “ any occupational risk that is both new and increasing ”, existing several studies carried out by the EU-OSHA where the set of the above mentioned risks is identified and analyzed, both general and specific. However, as demonstrated in recent studies, the direct use of this set of NER in risk assessment techniques, generally applied in industrial processes and in particular those characterized by advanced technology, may result in the identification of TR instead of NER, mainly due to the fact that they have been defined without following a risk reference model. In order to solve this problem, a risk model that improves and complements the EU-OSHA’s NER definition has been developed with the abovementioned investigations. However, this model has two limitations. First, the model does not contemplate the possibility of considering independently the new risks (NR) and increasing risks (IR). Second, this model does not allow monitoring NER evolution over time, therefore it is not currently possible to determine, in general, the temporary validity of such risks. Thus, the main objective of this work is to develop a theoretical framework for the modeling of the NER that allows its monitoring through the technology lifecycle (TLC), especially in industrial processes. To develop this framework, first it has been carried out an analysis of the limitations previously mentioned as well as the related literature. In this way, a theoretical context that allows to justify and argue properly the development of three new models for the NER, NR and IR has been set up. These named models allow, on the one hand, characterizing and differentiating the new qualities from the increasing qualities associated to risk. On the other hand, these models allow defining a set of risk typologies. These typologies have been associated with risk evolutionary phases likely to be integrated into the TLC, especially of a given industrial process, allowing monitoring over time of its NER. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
42. Risk identification in food safety: Strategy and outcomes of the EFSA emerging risks exchange network (EREN), 2010–2014.
- Author
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Costa, M.C., Goumperis, T., Andersson, W., Badiola, J., Ooms, W., Pongolini, S., Saegerman, C., Jurkovic, M., Tuominen, P., Tsigarida, E., Steinwider, J., Hölzl, C., Mikushinska, N., Gross-Bošković, A., Kanari, P., Christodoulidou, M., Babička, L., Korsgaard, H., Pesonen, S., and Fillet, A.M.
- Subjects
- *
FOOD safety , *AGRICULTURAL organizations , *INFORMATION sharing , *CONSUMERS , *FOOD consumption - Abstract
The European Food Safety Authority (EFSA) established an Emerging Risks Exchange Network (EREN) to exchange information between EFSA and the Member states (MSs) on possible emerging risks for food and feed safety in 2010. The Network is composed of delegates from MSs and Norway designated through the Advisory Forum of EFSA and observers from the European Commission, EU pre-accession countries, the Food and Drug Administration of the USA and the Food and Agricultural Organisation of the United Nations. Through 2010 to 2014, the EREN met 12 times. The EREN discussed a total of 63 signals of potential emerging issues that were presented and assessed using a standard template developed by the Emerging Risks unit of EFSA (EMRISK). Out of these signals, 39 originated from EFSA, 24 from MSs. The issues discussed were mainly microbiological and chemical hazards, but also food safety issues as result of illegal activity, new consumer consumption trends, biotoxins, new technologies and processes, allergens, animal health, environmental pollution, new analytical methods, new food packaging technology and unknown hazards were on the agenda. Based on the available evidence, EREN recommended whether an issue should be considered emerging or not, and if it merited further consideration, such as generating data on the issue, starting a full risk assessment and/or consultation of other bodies. According to the emerging risks identification process set in place at EFSA, the issues discussed and found of relevance by EREN were sent to the EFSA's Scientific Committee Standing Working Group on Emerging Risks for final evaluation. With four case studies, i.e the zoonotic potential of Usutu virus, risk of ciguatera fish poisoning in EU, zoonotic aspects of illegally imported wildlife products and benefits and risks of 3D food printing, the method developed to preliminary assess signals of potential emerging issues is presented and discussed. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
43. Emerging risk forecast system using associative index mining analysis.
- Author
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Kim, Joo-Chang and Chung, Kyungyong
- Subjects
- *
DATA mining , *INTERNET of things , *BIG data , *FORECASTING methodology , *REAL-time computing , *COMPUTER software , *MANAGEMENT - Abstract
Accessibility to the information increased by the development of IT converging technology and therefore various information such as economy, society, technology, culture and etc are distributed without limit to time and place. Data mining that discovers useful information by analyzing the data that accumulated to a large amount is receiving spotlight. By the distribution of IoT machine, the collection of life log has been eased and the interest on personalized service fit to the used is increasing. Companies and nationals use various analysis methods to develop big data that is accumulated for the safety of its people and asset into simple index. Meteorological Administration analyze the weather data and provide service through internet and app by developing weather index analyzing the extent of influence of weather on life, health and industry. The weather index measure by each region by using data collected real time at the weather observation point. Weather index is classified into the life weather index, health weather index and industry weather index by fields and provide coping measures per steps along with precautions. The weather index provided at this present is a simple service that did not consider the correlation of the index. Also it has a problem of not considering the situation by the location of the user. This study suggests emerging risk forecast system using associative index mining analysis. The suggesting method is the monitoring system focused on the user by analyzing the associative index using data mining and forecasting emerging risk by reflecting the user situation information. Index data collects the weather index XML file by using the Rest call method through the Meteorological Administration. The collected weather index analyzed the association relationship and interrelationship between the index by using the Apriori algorithm and Pearson correlation coefficient of the data mining. User situation information collects the surrounding temperature and humidity using the Zigbee communication. Collected temperature and humidity is applied to the daily weather index and health weather index and calculated fit for the situation of the user and the industry weather index is calculated focused on the user by using the association relationship and interrelationship between the index. By using the calculated weather index focused on the user, emerging risk of the life, health and industry scope is forecasted. Emerging risk is classified into life emerging risk, health emerging risk, industry emerging risk by the forecast method and is divided into four steps of low, general, high and danger. Emerging risk forecast system using the associative index mining analysis suggested provides precaution followed in the emerging risk and provides service such as weather index, weather information, user situation information etc of the Meteorological Administration. The suggested emerging risk forecasting system is the user based monitoring simulation that calculates the weather index real-time. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
44. Brain-computer interfaces in safety and security fields: Risks and applications.
- Author
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Brocal, F.
- Subjects
- *
BRAIN-computer interfaces , *DESIGN techniques , *CYBERTERRORISM - Abstract
• Risks and applications of BCIs are studied in safety and security fields. • Fatigue detection, safety control, and risk identification categories are linked to safety. • Cyberattacks and authentication categories are linked to security. • BCIs are both a source of risk and technology for risk prevention. • The BCI technology is analyzed as an emerging risk. With the recent increasing interest of researchers for Brain-Computer Interface (BCI), emerges a challenge for safety and security fields. Thus, the general objective of this research is to explore, from an engineering perspective, the trends and main research needs on the risks and applications of BCIs in safety and security fields. In addition, the specific objective is to explore the BCIs as an emerging risk. The method used consists of the sequential application of two phases. The first phase is carried out a scoping literature review. And with the second phase, the BCIs are analyzed as an emerging risk. With the first phase, thematic categories are analyzed. The categories are fatigue detection, safety control, and risk identification within the safety field. And within the security field are the categories cyberattacks and authentication. As a result, a trend is identified that considers the BCI as a source of risk and as a technology for risk prevention. Also, another trend based on the definitions and concepts of safety and security applied to BCIs is identified. Thus, "BCI safety" and "BCI security" are defined. The second phase proposes a general emerging risk framing of the BCI technology based on the qualitative results of type, level, and management strategies for emerging risk. These results define a framework for studying the safety and security of BCIs. In addition, there are two challenges. Firstly, to design techniques to assess the BCI risks. Secondly, probably more critical, to define the tolerability criteria of individual and social risk. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
45. The severity and extent of periodontitis is associated with cardio-ankle vascular index, a novel arterial stiffness parameter
- Author
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Orawan Charatkulangkun, Prin Vathesatogkit, Kansurang Chansawang, Thosaphol Limpijankit, Nisachon Siripaiboonpong, Lalitsara Thienpramuk, and Attawood Lertpimonchai
- Subjects
Adult ,medicine.medical_specialty ,Emerging risk ,Logistic regression ,Generalized periodontitis ,03 medical and health sciences ,Vascular Stiffness ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,Cardio-ankle vascular index ,Periodontitis ,General Dentistry ,Aged ,business.industry ,Attachment level ,030206 dentistry ,Middle Aged ,Thailand ,medicine.disease ,Cross-Sectional Studies ,030220 oncology & carcinogenesis ,Arterial stiffness ,Cardiology ,Ankle ,business - Abstract
To evaluate the association between the severity and extent of periodontitis and arterial stiffness using the cardio-ankle vascular index (CAVI). A cross-sectional study of 2888 Electricity Generation Authority of Thailand (EGAT) employees aged 44–78 years was conducted. The severity of periodontitis was evaluated based on mean clinical attachment level (CAL). The percentage of sites with CAL ≥ 5 mm was used to divide the extent of periodontitis into healthy (0%), localized (> 0–< 30%), and generalized (≥ 30%). The CAVI value, a novel blood pressure-independent arterial stiffness parameter, was analyzed as both continuous and categorical data (low: < 9 or high: ≥ 9). Regression analysis was used to estimate the level of association. The participants demonstrated a mean CAL, % sites with CAL ≥ 5 mm, and a CAVI value of 3.2 ± 1.2 mm, 16.0 ± 20.8%, and 8.24 ± 1.12, respectively. Higher mean CAVI was observed with greater mean CAL and % sites with CAL ≥ 5 mm. The mean CAVI of the healthy, localized, and generalized periodontitis groups were 8.01 ± 1.11, 8.22 ± 1.12, and 8.51 ± 1.04, respectively (p < 0.01). Linear and logistic regression analysis demonstrated a significant relationship between CAVI and all periodontal variables with β = 0.004–0.17 and OR = 1.01–1.58, respectively. There is a significant dose-dependent association between the severity and extent of periodontitis and arterial stiffness measured by CAVI in Thai adults. Preventing arterial stiffness, an early sign of cardiovascular events, by controlling the emerging risk factors, such as periodontitis, might have a high impact on health promotion.
- Published
- 2020
46. Postmarket Safety Communication for Protection of Public Health: A Comparison of Regulatory Policy in Australia, Canada, the European Union, and the United States
- Author
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Ameet Sarpatwari, Marie L. De Bruin, Joel Lexchin, Ruth Lopert, Barbara Mintzes, Alice Bhasale, and Priya Bahri
- Subjects
Canada ,medicine.medical_specialty ,Drug-Related Side Effects and Adverse Reactions ,Emerging risk ,030226 pharmacology & pharmacy ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Taverne ,Product Surveillance, Postmarketing ,medicine ,Adverse Drug Reaction Reporting Systems ,Humans ,media_common.cataloged_instance ,Risk communication ,Pharmacology (medical) ,European Union ,European union ,media_common ,Pharmacology ,business.industry ,Communication ,Public health ,Corporate governance ,Australia ,Legislature ,Regulatory policy ,Public relations ,Transparency (behavior) ,United States ,3. Good health ,030220 oncology & carcinogenesis ,Public Health ,Business - Abstract
In the wake of the withdrawal of the nonsteroidal anti-inflammatory drug rofecoxib, regulators worldwide reconsidered their approach to postmarket safety. Many have since adopted a “life cycle” approach to regulation of medicines, facilitating faster approval of new medicines while planning for potential postmarket safety issues. A crucial aspect of postmarket safety is the effective and timely communication of emerging risk information using postmarket safety advisories, commonly issued as letters to healthcare professionals, drug safety bulletins, media alerts, and website announcements. Yet regulators differ in their use of postmarket safety advisories. We examined the capacity of regulators in the United States, Europe, Canada, and Australia to warn about postmarket safety issues through safety advisories by assessing their governance, legislative authority, risk communication capabilities, and transparency.
- Published
- 2020
47. Investigation of Emerging Risk Factors and Isolation of Potential Pathogenic Bacteria from Domestic Dog Stool in Port Harcourt Metropolis, Niger Delta
- Author
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G.N. Wokem, Njoku-Tony R.F, Kemsi B, and Azuonwu O
- Subjects
Niger delta ,Isolation (health care) ,040301 veterinary sciences ,Emerging risk ,030231 tropical medicine ,Pathogenic bacteria ,04 agricultural and veterinary sciences ,Biology ,medicine.disease_cause ,Microbiology ,0403 veterinary science ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Port harcourt - Abstract
This study investigated the potential pathogenic bacteria that are associated with domestic dog stool in Port Harcourt Metropolis. Convenience sampling techniques were used for sample collection outcome. A total of fifty dog stool samples were collected aseptically into a sterile stool container from different locations (Agip Estate, Rumuokoro Community, Government Residential Area, Sand-fill Borokiri, Port Harcourt Township, and Rivers State University lecturers’ quarters) all within Port Harcourt City. Bacteriological analysis was determined using standard microbiological analytical and identification techniques. Statistical analysis was performed using Statistical Package for Social Science version 21 for frequency, percentage, prevalence rate and correlation at 0.01 and 0.05 level of significance. Potential pathogens with associated percentages that were isolated are E coli (20.0%), Klebsiella species (16.0%), Pseudomonas species (4.0%), Proteus species (28.0%), Bacillus species (4.0%), Staphylococcus aureus (14.0%), and unidentified [other Staphylococcus species] (4.0%). However, the research further revealed that Proteus species (28.0%), was the most prevalent pathogen, while Bacillus species (4.0%), Pseudomonas species (4.0%), and Streptococcus species (4.0%), were the least prevalent among pet dogs studied. The correlation analysis showed no significant relationship between isolates with socio-demographic data of pet owner and Pet biodata respectively. From the analysis, correlation coefficient values of .269 and .124 were obtained for Age of Pet Owner and Gender of Owner respectively. It also show a direct correlation but by implication, a very weak, non-significant (p0.05). Furthermore, negative non-significant correlation (p>0.05) was observed for marital status of Pet Owner (r=-.158) and Age of Pet (r=-.023) and isolate. Also, correlation association between isolates and some risk factors using the correlation analysis matrix revealed an indication of an indirect but moderate association between isolates and Caressing (r=-.347, p=0.01). However, other risk factors like vaccination (r=.042), Feeding Pattern(r=.125), Pet Bathing (r=.220) and Eating with pet in same plate (r=.146), did not prove statistical significance at p>0.05. The results from the study strongly suggest that pet dogs carry potential pathogenic organisms in their faecal matter that can serve as a source of infection to the pet owners. It is, therefore, very critical that these pets should be treated and possibly vaccinated frequently, even as their faecal matters should be well disposed to prevent possible zoonotic infectious epidemic outbreak in our global communities.
- Published
- 2020
48. Adulterants in selected dietary supplements and their detection methods
- Author
-
Flavia Redko, Jerónimo Luis Ulloa, and Liliana Muschietti
- Subjects
Emerging risk ,Pharmaceutical Science ,Poison control ,Overweight ,01 natural sciences ,Chemistry Techniques, Analytical ,Analytical Chemistry ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Environmental health ,medicine ,Humans ,Environmental Chemistry ,030216 legal & forensic medicine ,Health risk ,Adverse effect ,Spectroscopy ,business.industry ,010401 analytical chemistry ,medicine.disease ,Obesity ,0104 chemical sciences ,Erectile dysfunction ,Dietary Supplements ,medicine.symptom ,Drug Contamination ,business - Abstract
At present, there is a growing trend toward the intentional adulteration of dietary supplements (DS) with synthetic pharmaceuticals, which represents an alarming emerging risk to consumers and a serious problem for regulatory agencies. An amazing array of synthetic drugs and their analogues have been reported as adulterants in DS. Mainly, the presence of analogues represents a serious health risk as their efficacy and toxic effects have not been clinically assessed yet and may result in unpredictable adverse effects. The purpose of this review is to provide an overview, over the period 2009-2019, of the most frequently reported adulterants in DS for the treatment of erectile dysfunction, obesity/overweight, diabetes mellitus, and hypertension and the analytical methods used for their detection.
- Published
- 2020
49. Understanding Risk Information Seeking and Processing during an Infectious Disease Outbreak: The Case of Zika Virus
- Author
-
Austin Hubner and Shelly R. Hovick
- Subjects
Adult ,Male ,Emerging risk ,Information Seeking Behavior ,Applied psychology ,0211 other engineering and technologies ,Online study ,02 engineering and technology ,010501 environmental sciences ,01 natural sciences ,Disease Outbreaks ,Zika virus ,Young Adult ,Pregnancy ,Physiology (medical) ,Humans ,Safety, Risk, Reliability and Quality ,0105 earth and related environmental sciences ,021110 strategic, defence & security studies ,biology ,Zika Virus Infection ,Information seeking ,Outbreak ,biology.organism_classification ,Risk perception ,Infectious disease (medical specialty) ,Childbearing age ,Florida ,Female ,Psychology - Abstract
This study draws on the Planned Risk Information Seeking Model (PRISM) to assess Zika virus information seeking and systematic processing, paying particular attention to the relationship between perceived knowledge and knowledge insufficiency. Novel risks, such as Zika, provide an interesting context for examining whether information-seeking models, such as PRISM, are able to predict information seeking when available information is limited or scarce. A cross-sectional, online study of men and women of childbearing age (N = 494) residing in the state of Florida was conducted. Our results provide some support for the PRISM for predicting Zika information seeking intention, as well as systematic processing of information. We also found that individuals with high levels of perceived knowledge were more likely to report high level of knowledge insufficiency, illustrating that contextual factors may impact the fit of risk information seeking models.
- Published
- 2020
50. Periprostatic adipose tissue: A heavy player in prostate cancer progression
- Author
-
Catherine Muller, Mathieu Roumiguié, Cécile Manceau, David Estève, and Delphine Milhas
- Subjects
0301 basic medicine ,business.industry ,Emerging risk ,Endocrinology, Diabetes and Metabolism ,Adipose tissue ,030209 endocrinology & metabolism ,Paracrine mechanisms ,medicine.disease ,03 medical and health sciences ,Prostate cancer ,030104 developmental biology ,0302 clinical medicine ,medicine.anatomical_structure ,Periprostatic ,Prostate ,Cancer research ,Endocrine system ,Medicine ,business ,Metabolic profile - Abstract
Prostate is surrounded by a specific fat depot called periprostatic adipose tissue (PPAT) that contributes through paracrine mechanisms to prostate cancer (PCa) progression. Like other white adipose tissues, PPAT stores lipids and is an endocrine organ. However, PPAT is still poorly characterized. Nevertheless, current evidence highlights that soluble factors secreted from PPAT might promote PCa aggressiveness and local dissemination. In addition, the ability of adipocytes to provide lipids to tumor cells participates in tumor aggressiveness. The secretory and metabolic profile of PPAT is modified by obesity, a state associated with greater occurrences of aggressive diseases. Beyond obesity, the excessive accumulation of PPAT, independently of the ponderal status of the patients, is an emerging risk factor in aggressive diseases. Characterization of the role of human PPAT on PCa progression will undoubtedly provide, in the near future, new therapeutic strategies and new risk stratification factors in PCa.
- Published
- 2020
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