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Aim: White spot lesions are the only carious process lesions that can be remineralized non-invasively. The focus of modern dentistry is stopping the caries process without unnecessary damaging the tooth structure. The present clinical trial aimed to assess the remineralizing effect of eggshell powder (ESP) compared to Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) in carious post-orthodontic white spot lesions orthodontic treatment. Methodology: Twenty-Four patients were selected from the Clinic of Orthodontic Dentistry Department, Faculty of Dentistry, Cairo University. Patients were divided into two groups according to the treatment received either ESP gel or CPP-ACP paste (GC Tooth-Mousse). The participants were instructed to use pea size eggshell powder gel or GC Tooth Mousse on the teeth surfaces using a clean finger twice daily after brushing their teeth with Colgate Total Original Care toothpaste. WSLs were assessed at baseline, 1 month, 3months and 6 months by DIAGNOdent (Kavo, Germany). Results: Data were analyzed using Two-way ANOVA showed that there was no statistically significant difference in overall DIAGNOdent mean readings between ESP and GC Tooth Mousse groups at (P=0.136). Conclusion: Based on the data obtained in this study, it is suggested that ESP is effective and has a promising future in the treatment of post-orthodontic WSLs.

Objective: To compare the mean dentin hypersensitivity after using GC tooth mousse versus fluoride varnish in patients with dentinal hypersensitivity due to non-carious cervical lesions. Study Design: Randomized Control Trial. Setting: Watim Dental College, Rawalpindi. Period: February to August 2019. Material & Methods: A total number of 166 patients were enrolled in the study. Informed consent and demographic information were taken. The subjects were randomized by using random number table to minimize bias. Patients were divided into 2 groups. Fluoride varnish (group 1) which is the control group and GC Tooth Mousse which is group 2, both were used 3 times in the first day during the first week. On follow up the tooth sensitivity was noted. The follow up appointment to measure the level of dentinal hypersensitivity was done after the given treatment on the 7th day of the first week. For measuring the dentin hypersensitivity, the Visual Analogue Scale was used. The data that was collected was entered and 1 then it was analyzed on SPSS version 21. Results: In this study mean age of the fluoride varnish group patients was 44.14±8.95 years, in GC tooth mousse group patients was 44.24±9.04 years. The mean pain score of fluoride varnish group patients was 1.98±1.43 while in GC Tooth Mousse paste group patients was 2.39±1.21 (p-value=0.048). Conclusion: Fluoride varnish group showed significantly lower mean dentin hypersensitivity than to GC tooth mousse group in patients with dentinal hypersensitivity with caries free cervical lesions.

Background: In preventive dentistry, it is important for the need to prevent rather than to treat early childhood caries and to improve the types of fluoride and application to see if the comparative efficacy is sufficient or insufficient because every type can relieve and give comfort to patients. Aims: To compare the effect of Silver Diamine Fluoride (SDF), fluoride varnish, fluoride gel and GC tooth mousse plus on Streptococcus mutants bacterial load. To evaluate the effect on the types of fluoride on caries. To compare the effect of prevention’s of early childhood caries by using different types of fluoride. Searching the databases using the keywords: sodium diamine fluoride; GC tooth mousse; fluoride varnish; fluoride gel; early childhood caries; caries; varnish; prevention. Materials and methods: 2010-December 2018, databases which were searched: MEDLINE via Ovid, Web of science, Embase, Cochrane Library, LILACS, and Dental specialties: pediatrics, oral preventive. Foreigner languages, editorials, letter to the editor, experimental studies with animals and Short communications were excluded from this review. Results: 2 studies assessed un-clear and need further research of SDF. 5 studies assessed that 12% of SDF has no effect but 38% has an effect with dentin and enamel with black staining as a disadvantage. 1 study showed that SDF is safe and effective compared to fluoride varnish, 2 studies showed that tooth mousse is recommended for early child caries without mentioning SDF and 3 studies found that it decreases the growth of mutants and aids in the remineralization of both enamel and dentin structure. Conclusion: To sum up this study silver diamine fluoride is effective and safe to use for preventing childhood caries than silver fluoride, GC tooth mousse and fluoride varnish, which saves time with increase accuracy and patient satisfaction.

Aim: The aim is to compare the effects of diode laser, GC tooth mousse, and sodium fluoride (NaF) varnish on dentinal hypersensitivity by scanning electron microscopic (SEM) evaluation. Materials and Methods: Forty extracted human maxillary first premolar teeth were selected to prepare dentin disc of 2 mm thickness. The specimens were divided into four groups of 10 discs each-Group 1: Negative control, Group 2: Diode laser, Group 3: GC tooth mousse, and Group 4: NaF varnish. Diode laser and NaF was exposed on dentin disc for three consecutive days. GC tooth mousse was applied twice a day for 1 week. All the specimens were examined under SEM at a magnification of ×1500. The standardized SEM microphotographs were analyzed according to the scoring criteria. Statistical Analysis: Friedman test with post hoc Wilcoxon sign rank test for pair wise comparison at different time intervals within the group was computed using SPSS version 20. A P < 0.05 was regarded as statistically significant. Results: The results showed that the use of diode laser was able to achieve complete occlusion of dentinal tubules followed by the use of GC tooth mousse and that of NaF varnish while control group showed completely open tubules. Conclusions: Irradiation of dentinal tubules using diode laser could be effective for routine clinical treatment of dentinal hypersensitivity compared to NaF and GC tooth mousse.

Aim: Teeth are constantly going through cycles of demineralization and remineralization. The ultimate goal of clinical intervention is the preservation of tooth structure and the prevention of lesion progression to the point where restoration is required. Thus promoting remineralization is the ultimate goal of clinical prevention of caries lesion. The present in vitro study aimed to investigate the efficacy of GC Tooth Mousse (CPP-ACP) and GC Tooth Mousse Plus (CPP-ACP)F on artificial enamel caries in primary human teeth. Methods and Material: Sixty freshly extracted human primary anterior teeth were used in this study. The root portion of 60 primary anterior teeth was separated from the crown portion at the cemento-enamel junction (CEJ) Teeth samples were divided into 3 Groups (n=20 each). Group 1 as a control group, Group 2 GC Tooth Mousse, and Group 3 Tooth Mousse Plus containing dentifrices were used. Samples were subjected to 10 days of pH cycling protocol. The changes were analyzed using Vickers Hardness Testing Machine and SEM. Pre and post groups were compared by paired t-test. Independent groups were compared by one-way analysis of variance. Result: Micro-morphological observations of the enamel surfaces with SEM : Group 1 the enamel scanning showed shallow depressions and fine porosities within these depressions, Group 2 showed numerous granular particles and amorphous crystals which were arranged on the enamel surface. Smooth, homogeneous surface, and no irregularities were seen in Group 3. Surface Microhardness Evaluation After treatment, the mean hardness Group III was the highest followed by Group II and Group I (i.e. Group I < Group II < Group III). Conclusion: GC Tooth Mousse Plus showed a statistically significant amount of remineralization.

Aim To compare and evaluate the caries preventive effectiveness of resin infiltrant (ICON), casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) (GC Tooth Mousse), and nanohydroxyapatite (Aclaim) on incipient enamel lesions. Materials and methods A total of 60 human maxillary incisors extracted for periodontal reasons were included in this study. The sectioning was done at the middle third region of the crown for the 60 samples with approximate dimensions of 5 × 5 × 5 mm). In order to create the artificial enamel lesions, the samples were demineralized by placing in a beaker containing the prepared demineralizing solution for 14 days. The study samples were then divided into four groups that are resin infiltrant (group I), CPP-ACP (group II), nanohydroxyapatite (group III), and control (group IV) with 15 enamel samples in each group. The caries preventive efficacy of each group was evaluated using a confocal laser scanning microscope. Results The mean values after demineralization of enamel samples in demineralizing solution are 245 μm for resin infiltrant (group I), 246 μm for CPP-ACP (group II), 250 μm for nanohydroxyapatite (group III), and 247 μm for control (group IV). After remineralizing the enamel samples for a period of 30 days, the results are group I (resin infiltrant) 158 μm > group II (CPP-ACP) 28.8μm ≥ group III (nanohydroxyapatite) 26.3 μm. After subjecting it to demineralizing solution again for 14 days, the amount of material that was resistant to acid attack was group I (resin infiltrant) 114 μm (72%) > group III (CPP-ACP) 16.4 μm (57%) ≥ group III (nanohydroxyapatite) 13.8 μm (50%). The untreated control group showed increased progression of lesion and least resistance to acid challenge. Conclusion Based on the results from this in vitro study, it can be concluded that when compared to the two remineralizing agents the resin infiltrant showed better caries preventive effectiveness. Clinical significance Resin infiltrants have a favorable penetration potential in subsurface or incipient enamel lesions.

The results of the own investigations are represented in this work. The analysis of the clinical findings, the positive dynamics of saliva microcrystallization proves the efficacy of remineralizing GC Touth Mousse preparation in the treatment of the initial caries, in remineralization of non-caries lesions and hard teeth tissues with unfinished mineralization.

To compare the effects of a fluoride dentifrice alone, versus a topical CPP–ACP creme used as a dentifrice, versus the combination of both agents (fluoride dentifrice followed by CPP–ACP creme) on early caries lesions (ECL) in primary anterior teeth of children over a 6-month period. In this single blinded randomised clinical trial, children (n = 114, aged 4–5 years) with high caries risk and who had at least one ECL (ICDAS 2) on their primary anterior teeth were allocated to three groups. Subjects used different agents twice daily: fluoride dentifrice (500 ppm F, n = 42), CPP–ACP creme (10% w/v, n = 35), and the fluoride dentifrice followed by CPP–ACP creme (n = 37). Changes in lesions were tracked using QLF, comparing the baseline situation to 3 and 6 months of treatment. QLF changes consistent with mineral gain (∆F/fluorescence, lesion area) occurred in all three groups (baseline versus 3 months or 6 months, p ≤ 0.05 for all three groups). Differences between treatment groups were not statistically significant (p > 0.05). The topical CPP–ACP creme used alone gave effects similar to the fluoride dentifrice; however, the combination of the two did not give additive benefits over either agent used in isolation.

Context: Avulsion injury is a severe form of dental trauma. Due to the complexity of this injury, the neurovascular supply is severely compromised and usually results in the loss of pulp vitality. A variety of factors can influence the success of replantation especially the storage media and storage period. Casein phosphopeptides are derived from casein which accounts for 80% of the total protein in bovine milk. They can function as carriers for several minerals especially calcium and also have known to have antibacterial properties. Aim: The purpose of this study is to evaluate the efficacy of GC Tooth Mousse Plus in comparison with chilled Homogenous pasteurized whole milk as a storage media. Materials and Methods: Thirty healthy premolars that are extracted for orthodontic purpose will be divided into three groups: (1) Group A: Control (Saline), (2) Group B: Positive control (Chilled Homogenous milk), (3) Group C: Experimental (GC Tooth Mouse Plus). These groups were further divided into two subgroups, each indicating storage period of 30 min and 60 min. The periodontal ligament (PDL) cell viability will be checked using tryphan blue staining. Results: Data were analyzed using Student's t-test. Conclusion: GC Tooth Mousse Plus can be used as a storage media to prevent desiccation of PDL cells up to the duration of 60 min.

Severe dental erosion could be one of the complications of gastroesophageal reflux disease and food disorders such as bulimia nervosa. The aim of the present in vitro study was to evaluate the remineralization efficiency and the erosion prevention capability obtained by combining the use of Elmex Erosion Protection (Elm-EP) and GC Tooth Mousse (GC-TM) in cases of strongly eroded enamel surfaces. Twenty-four specimens of bovine tooth were superficially treated with hydrochloric acid to mimic severe erosion conditions. The specimens were divided into 3 groups accordingly to a different remineralizing treatment for 15 days: immersion in artificial remineralizing saliva, brushing with Elm-EP and brushing with Elm-EP in association with a daily application of GC-TM paste. After the remineralization procedures, the specimens were exposed to a treatment with acid. The effectiveness of the treatments were assessed by surface profilometric analysis and scanning electron microscopy at four different steps. Furthermore, the quantity of the Ca2+ lost during erosion was determined. The combined action of Elm-EP and GC-TM led to a 50% roughness decrease of critically eroded dental surfaces. The tandem use of Elmex Erosion Protection and GC Tooth Mousse resulted a promising protecting strategy for the prevention of the dental mineral loss.

Aim: To compare and evaluate the remineralizing potential of four commercially available products namely SHY-NM, GC Tooth Mousse Plus, ReminPro and Colgate strong teeth on demineralized human teeth. Materials and methods: The study included 50 extracted premolars having 3 × 3 mm window prepared on the middle third of the tooth, which was then subjected to demineralization for 48 hours at 37°C. Teeth were randomly selected and grouped into five study groups of 10 teeth in each. Each group was treated with respective remineralizing agent and sectioned using hard-tissue microtome. Each section obtained was visualized under polarized light microscope and analyzed using Image J software. Results: The statistically evaluated results revealed that SHY-NM has the most remineralizing potential followed by ReminPro, GC Tooth Mousse Plus and fluoridated toothpaste. Conclusion: Based on the study, the SHY-NM was superior to the GC Tooth Mousse Plus, ReminPro and Colgate strong teeth on demineralized human teeth. How to cite this article: Rajan R, Krishnan R, Bhaskaran B, Kumar SV. A Polarized Light Microscopic Study to Comparatively evaluate Four Remineralizing Agents on Enamel viz CPP-ACPF, ReminPro, SHY-NM and Colgate Strong Teeth. Int J Clin Pediatr Dent 2015;8(1):42-47.

Objective: This study evaluated the ability of 30% ethanolic extract of Indian propolis on dentinal tubule occlusion comparatively against CPP-ACP containing desensitizing agent GC tooth mousse. Methodology: The specimens were prepared from 30 freshly extracted sound human third molars stored in 10% formalin (pH 7.0) at a room temperature. From each specimen, a sectioned sample (5 mm length × 5 mm width × 3.5 mm depth) was obtained including the cervical area. Samples were smoothened and wet-polished with 1000- and 1200-grit aluminum oxide abrasive paper and diamond pastes, in order to stimulate the clinical aspect of hypersensitive dentin cervical surfaces. All the specimens were randomly assigned to three groups (n = 10), according to dentin surface treatments. Negative control: Untreated specimens (n = 4) and pretreated with 6% citric acid (n = 6); Test Group: 30% ethanolic extract of Indian propolis (n = 10); Positive Group: GC Tooth Mousse (n =10). All the specimens were prepared for SEM analysis. Results: GC tooth mousse promoted tubule occlusion by crystal-like deposits in the lumen of the tubules. While propolis created a thin, smooth layer over dentin surface. Conclusion: According to the SEM analysis, both desensitizing agent were able to occlude the dentinal tubules.

Aims and objectives: Fixed orthodontic treatment makes oral hygiene procedures difficult and may result in enamel demineralization. Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) with fluorides (GC Tooth Mousse Plus) reduces the incidence of enamel demineralization. The objective of this study was to evaluate the effects of GC Tooth Mousse Plus application, on enamel demineralization in patients undergoing orthodontic treatment. Methodology: Thirty subjects seeking orthodontic treatment were selected from patients visiting Department of Orthodontics in AB Shetty Memorial Institute of Dental Sciences, Mangalore. The subjects were divided into test and control group, and scanning electron microscopic (SEM) evaluation was done to compare level of surface roughness on samples of both the groups. Results: No white spot lesion was clinically appreciable in either test or control group. After extracting the teeth, SEM images of surface of the teeth was graded and statistically evaluated with Pearson′s Chi-square and likelihood ratio test. The results were significant with p-value below 0.001 which indicated increased surface roughness in controls compared to the test group patients. Conclusion: Use of CCP-ACP with fluorides (GCTM+) as an adjunctive to thorough oral hygiene measures has proven to be effective in reducing enamel demineralization significantly.

Dental caries is still one of the main diseases dealt with by dentistry, and its diagnosis, prophylaxis and treatment occupy the leading place in therapeutical dentistry. the range of products applied in remineralizing therapy is quite wide. the authors of this article study gc tooth mousse and gc mi paste plus as being the most effective for control over tooth hard tissue de- and remineralization process.

Objective Casein phosphopeptide-amorphous calcium phosphate nanocomplexes (CPP-ACP) exhibit anticariogenic potential in laboratory, animal and human experiments. The remineralising potential of synthetic CPPs on early enamel caries was investigated. Design In vivo study. Setting University of Naples 'Federico II', School of Dentistry, Department of Paediatric Dentistry, 2010, Italy. Participants 40 volunteers (age range 10-16 years) were recruited and divided in two groups of 20 (Group A and B). Interventions In Group A subjects two demineralised enamel specimens were placed on the buccal surfaces of the first molars and subjects were instructed to apply a commercial product containing CPPs (GC Tooth Mousse) only on the right-sided specimen and a placebo mousse on the left, for 1 month. In Group B subjects two enamel specimens were similarly placed into the mouth and used as controls. Results SEM analysis revealed a diffuse and homogeneous mineral coating, reducing the surface alterations only in the demineralised specimens treated with synthetic CPPs into the mouth. Conclusions Results demonstrate that CPPs are able to promote remineralisation of early enamel lesions.

Introduction. Decaltification on the teeth around the orthodontic braces can be reduced with adequate oral hygiene and use of fluorides. Aim. The aim of this study was to examine, using scanning electron microscopy, the ultrastructural changes on enamel surface after the treatment with different fluoride preparations. Methods. Orthodontic braces were placed on 30 dental samples (premolars) extracted for orthodontic reasons and orthodontic braces fixed with Fuji Ortho LC. The teeth were divided into three groups with 10 teeth each. First group was the control one, without treatment with fluoride solutions. Second group consisted of teeth samples treated with Fluorogal (0.05% F), every day for 1 minute in the period of 6 months. Third group consisted of teeth samples treated 5 minutes daily with GC Tooth Mousse in the period of 6 months. The teeth were placed in artificial saliva in the period of 6 months. Afterwards, the samples were prepared for scanning electron microscopy, SEM (JEOL JSM 5300) using the technique of sputtering in a vacuum evaporator. Enamel surface was analyzed in order to identify micromorphologic structural changes on the places where braces had been previously fixated. Results. The results indicated that SEM analysis detected the highest remineralization potential in the tooth samples exposed daily to low doses of fluoride. Conclusion. Remineralization of demineralized enamel was present in both experimental groups of teeth, being more intense in the group treated with Fluorogal solution.

Background and Objectives: This study compares the Salivary Calcium, Phosphate and Alkaline Phosphataselevels in children with Early Childhood Caries after administration of Milk, Cheese and GC Tooth Mousse to a control group of caries resistant children. Study design: 90 kindergarten children both males and females aged 5 years, from the South Canara region were included in the study. Based on the dmfs score, children were divided into 3 groups: Control group, ECC group and S-ECC group. The Salivary Calcium, Phosphate and Alkaline Phosphatase levels in the sample were assessed before and after administration of Milk, Cheese and GC Tooth Mousse at three different intervals, i.e within 5 minutes, 30 minutes and 60 minutes by using Spectrophotometry. Results: The mean Salivary Calcium levels were higher in caries free group whereas Phosphate and Alkaline Phosphatase were lower in the caries free group which was statistically highly significant (p

Objective: A randomized, double blind, split mouth, controlled clinical trial was conducted to evaluate the effect of two desensitizing agents on reduction of Dentin Hypersensitivity (DH). Material and Methodology: A sample of 73 teeth from 13 patients, among which at least 3 teeth had dentin hypersensitivity, was randomly allocated into 3 treatment groups: Group A: treated with 30% ethenolic extract of Indian Propolis, Group B: treated with GC tooth mousse, and Group C: treated with sterile water. A Verbal Rating Scale (VRS) was used to record the degree of hypersensitivity, based on patient’s response to tactile and air blast stimuli. The baseline scores were obtained. Each intervention group received applications of their respective agents consecutively on 1st, 7th, 14th and 21st days. After each application, the scores were recorded. Results: Both the 30% Indian Propolis and GC tooth mousse showed significant reductions in dentin hypersensitivity. Conclusion: GC tooth mousse was found to be significantly better in reducing the dentinal hypersensitivity as compared to Propolis and sterile water (p< 0.01).

A 19-year-old male was referred to the School of Dentistry, University of Queensland for management and treatment of uncontrolled root caries. A total of 12 teeth had non-cavitated root carious lesions requiring treatment. The lesions were treated with a daily application of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP; GC Tooth Mousse) and in-surgery photo-activated disinfection (PAD). Laser fluorescence (KaVo Diagnodent) was used to monitor the changes in the carious lesions. The combination of CPP-ACP and PAD proved to be very effective and holds great potential as a recommended treatment for stabilising root surface caries in the clinical practice.

The demineralization of enamel adjacent to orthodontic brackets is a significant clinical problem. The purpose of this in-vitro study was to investigate the effect of sodium fluoride (Colgate Neutrafluor 9000 ppm) (NaF) and 10% casein phosphopeptide-amorphous calcium phosphate (GC Tooth Mousse) (TM) on enamel demineralization adjacent to orthodontic brackets.Forty specimens were sectioned from the buccal or lingual surfaces of extracted sound third molars. Twenty specimens had molar tubes bonded with composite resin (Transbond XT, 3M, St Paul, Minn) (CR), and 20 were bonded with resin-modified glass ionomer cement (Fuji Ortho LC, GC America, Alsip, Ill) (RMGIC). A 2-mm window for enamel demineralization was prepared. The specimens were randomly divided into 4 treatment groups: control, TM, TM/NaF (50/50 w/w), and NaF. The treatment solutions were placed around the bracket margins, and the specimens were immersed inverted into a carbopol demineralization solution at 37 degrees C. The enamel specimens were exposed for 96 hours, with the demineralization and topical solutions changed every 4 hours. Quantitative light-induced fluorescence (QLF) images were taken every 8 hours under controlled conditions. The difference in fluorescence (DeltaF) and the proportional DeltaF (%F) change between baseline and 96 hours was calculated.RMGIC significantly reduced DeltaF and %F when compared with CR (ANOVA, P = .029 and P = .034, respectively). Application of TM with CR, NaF with CR, and TM/NaF with CR significantly reduced DeltaF and %F compared with the control CR (Tukey post-hoc test, P.001). Application of TM/NaF with RMGIC significantly reduced DeltaF and %F compared with the control RMGIC (Tukey post-hoc test, P = .008, P = .019, respectively).With the limitations of any in-vitro study, the following clinical conclusions can be drawn. The use of RMGIC alone can significantly decrease enamel demineralization compared with CR. The application of TM/NaF can provide significant additional prevention of enamel demineralization when RMGIC is used for bonding. The application of TM, NaF, or TM/NaF can significantly prevent enamel demineralization when CR is used for bonding. The use of both agents should be recommended for any at-risk orthodontic patient to provide preventive actions and potentially remineralize early (subclinical) enamel demineralization.

The aim is to evaluate the effect of McInnes bleaching agent on the microhardness of enamel before and after bleaching and to evaluate the effect of G C Tooth Mousse on the bleached enamel surface for its microhardness. The materials and methods used are McInnes bleaching solution, Casein phosphopeptide-amorphous calcium phosphate CCP-ACP (G C Tooth mousse) artificial saliva (Dept. of Oral Pathology, GDC Bellary), deionized water, Vickers’ Micro Hardness tester (Zwick/ZHV, Germany), freshly extracted teeth, cold cure acrylic, Diamond disc (Horico–PFINGST New Jersey, USA, KAVO-Germany), straight handpiece (kavopecareta) and plastic moulds (6.5 × 2 mm2). The purpose of this study was to evaluate and compare microhardness of the sound enamel surface by Vickers’ Hardness Number (VHN) before and after bleaching with McInnes solution, and to evaluate the effect of casein phosphopeptide amorphous calcium phosphate (G C Tooth Mousse) on the bleached enamel surface for its microhardness. The data obtained from the test were subjected for statistical analysis and are presented as range, mean and standard deviation. P value of 0.05 or less was considered for statistical significance. The changes in microhardness at different times of assessment were analyzed using the paired ‘t’ test. The results of all the samples showed decrease in the microhardness after two cycles of bleaching, though immediately after bleaching the decrease in the microhardness was not significant (P = 0.34). However, after the second cycles, it showed a significant decrease (P

Oral and mineral balance is affected by many factors and a shift towards an acidic environment can lead to demineralization of the enamel. Jane Lewis describes how GC Tooth Mousse is a useful clinical aid to restore mineral balance and prevent loss of enamel in a range of conditions