1. Synthesis of substituted hydantoins in low melting mixtures
- Author
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Sundarababu Baskaran, Burkhard König, Kiran Chinthapally, and Sangram Gore
- Subjects
ddc:540 ,hydantoin derivative ,Molecular Conformation ,Crystallography, X-Ray ,Phase Transition ,Catalysis ,Domino ,oxoacid ,chemistry.chemical_compound ,selective androgen receptor modulator ,Materials Chemistry ,Urea ,Organic chemistry ,aplysinopsin ,Tartrates ,Reaction conditions ,Chemistry ,Hydantoins ,phenytoin ,Metals and Alloys ,glpg 0492 ,General Chemistry ,Hydantoin ,unclassified drug ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,drug structure ,cytotoxic agent ,540 Chemie ,Solvents ,Ceramics and Composites ,Hydantoin derivatives ,drug synthesis ,dantrolene - Abstract
A novel domino synthesis of 1,3,5-trisubstituted hydantoin derivatives has been developed in low melting l-(+)-tartaric acid-DMU melt mixtures. The functionalized hydantoins are obtained in good yields from ?,?- unsaturated ketoacids and urea under environmentally benign and simple reaction conditions. � The Royal Society of Chemistry 2013.
- Published
- 2013
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