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HIGHLIGHTS • Complementary treatments have been shown to greatly reduce the intesity of dysminorrhea pain. • The use of medicinal plants, herbal concoctions, or compresses might reduce dysmenorrhea discomfort more effectively than taking medications like mefenamic acid, ibuprofen, piroxicam, etc. ABSTRACT Objective: The study's objective was to obtain latest data on alternative therapy for dysmenorrhea in adolescent females of reproductive age. Materials and Methods: A scoping review was conducted using the PRISMA ScR protocol. A search was conducted on PubMed, Science Direct, and Wiley, yielding 848 studies. Ten literature studies were identified that satisfied the criteria for population, exposure, and outcome. The studies also incorporated inclusion criteria, focusing on women of reproductive age who had dysmenorrhea. Results: Out of 848 articles, 32 were considered potentially relevant and met the inclusion criteria. The articles indicated that teenagers commonly used warm compresses and herbal drinks as supplementary therapies to alleviate dys-menorrhea due to their perceived effectiveness and comfort. Other complement-ary therapies for the condition included massage, relaxation, herbal products, self-care practices, acupuncture, and therapeutic methods. Conclusion: Herbal and warm water compress are the most commonly applied alternative therapies for treating dysmenorrhea.

This service activity aims to improve the understanding and skills of farmer groups in innovating Maiq Tulen herbal drinks. This method of implementing service using training with partners was a member of the Pade Angen Farmer Group in Peresak Village, West Lombok. Evaluation of activities was carried out by providing pre test and post test to participants to measure the success of service activities, which were then analyzed descriptively. The results of this service activity showed that the increasing understanding and skills of Pade Angen farmer group members in making Maiq Tulen herbal drinks into powder drinks based on their uses, namely Pegal Linu, Stamina, and Femininity to produce Maiq Tulen products that were more varied and favored by consumers. In addition, farmer groups also could package products. Based on the activities' results, the PkM team also assisted in the form of flour equipment, stoves, packaging, and several other supporting tools.

Binahong leaves are a plant that contains antioxidant compounds so that can be used as herbal drinks. Stevia leaves can be used as a sweetener with antioxidant compounds that can improve the taste of herbal drinks. This study aims to determine the effect of variations in drying temperature and herbal drink formulations in physical characteristics of color, chemistry including moisture content, phenol total, and antioxidant activity, as well as sensory parameters including color, smell, taste, and overall. Besides knowing the best treatment of variations in drying temperature and herbal drink formulation. This study used a Factorial Completely Randomized Design (FCRD) with two factors, namely variations in drying temperature and formulation. The drying temperature used were 55 °C, 60 °C, and 65 °C, while the binahong leaves : stevia leaves formulation used were 87.5 % : 12.5 %; 75 % : 25 %; and 62.5 % : 37.5 %. Based on the results of this study, it was found that the physical, chemical, and sensory characteristics can be influenced by the treatment of variations in drying temperature and herbal drink formulations. The best treatment for herbal drinks with variations in drying temperature and the formulation used was drying at 55 °C with the binahong leaves : stevia leaves formulation is 62.5 % : 37.5 %. The resulting characteristics are: brightness (L*) 39.605; reddish (a*) -2.307; yellowish (b*) 12.480; moisture content 7.617 %; phenol total 62.525 mg GAE/g; antioxidant activity 94.520 %, with the appearance of a yellow-brown color; the distinctive smell; sweet taste with a bitter aftertaste; and overall the panelists’ acceptance level was rather like..

The Republic of Kazakhstan has a unique natural and climatic potential for the production of beekeeping products with high functional properties. Today, Kazakhstan produces about 12 thousand tons of honey per year, but the share of honey used in the production of functional non-alcoholic and alcoholic drinks does not exceed 1 %. Often, such products are made at home or purchased imported. Based on the foregoing, the task of expanding the range of natural domestic soft drinks based on beekeeping products with high functional properties and the content of biologically active substances is relevant. This article presents the results of the development of new formulations of herbal drinks based on beekeeping products (honey) and ginger. The proposed products will have a healing effect due to the use of raw materials with high functional properties. In total, in the course of the work, 40 recipes were compiled with different contents of the feedstock, out of 40 options, 5 recipes were selected that are most attractive in terms of taste and quality characteristics, 4 of which were prepared by blending and fermentation, and 1 recipe only by blending. The results of the physicochemical characteristics of the selected recipes are given, the drinks correspond to the standard indicators of non-alcoholic and low-alcohol drinks.

Objectives: This investigation aimed to compare caffeinated gums with two different dosages of caffeine (200mg vs. 300mg) by assessing their effectiveness on the improvement of cognitive functions among Iranian individuals voluntarily suffering from 30 hours of sleep deprivation. Material and Methods: Thirty-four healthy male volunteers with ages from 28 to 35 years old were randomly assigned to either 200 or 300mg caffeine intake. Each participant completed CANTAB subtests to assess their core cognitive functions including MOT, RTI, RVP, and SWM before and after sleep deprivation, as well as after being treated with caffeinated gum. Results: The 300mg caffeine intake group indicated higher levels of enhancement of core cognitive functions compared with those in the 200mg caffeine intake group. Conclusion: This study suggests that the dose of 300mg of caffeine could effectively enhance the cognitive functions of Iranian individuals suffering from sleep deprivation.

Manuka and forest honeys are types of honeys that are widely consumed because for their antioxidant properties. In this study, the properties of forets and manuka honey and the use of honey as a herbal drink with the addition of Qusthul hindi and turmeric were analyzed. The addition of Qusthul hindi (0,125 g and 0,375 g) and turmeric (0,125 g and 0,375 g) is given in two formulations. This study was conducted in two phase, namely analyzing the characteristics of manuka and forest honey and preparing herbal drinks to then analyzing their properties. The results showed that the properties of forest honey do not meet the standards for the variables of pH, HMF value, and diastase enzyme activity, while Manuka honey meets the standards only for variables of moisture, HMF value, and diastase enzyme activity. The addition of Qusthul hindi and turmeric to herbal drinks results in an increase in pH, DPPH inhibitoty activity, and antioxidant capacity, as well as a decrease of water content, but is not sensory evaluated because the addition of spices causes changes in taste and appearance.

Foods that contain live probiotics and prebiotic compounds at the same time are called "synbiotics." Inulin is one of the prebiotics, the most important source of industrial extraction of which is chicory, jerusalem artichoke and garlic. The aim of this study was to determine the appropriate percentages of chicory, garlic and jerusalem artichoke for the production of synbiotic herbal tea with desirable PHysicochemical, microbial and sensory properties. For the preparation of synbiotic tea, different percentages of chicory (10 and 20%), jerusalem artichoke (10 and 20%) and garlic (0.5 and 1%) were prepared. Then Lactobacillus acidoPHilus (1%) was inoculated and aqueous extraction was performed mixed with water at 55- 60 ° C for 10 minutes. The chemical properties (brix, turbidity, PH, compounds and antioxidant activity), microbial and sensory properties of the drug were investigated. Also from black cumin (0.16 g), chamomile (3 g), cinnamon (0.12 g), fennel (0.2 g), mint (3 g) and licorice (0.1 g) as The filler was used in the preparation of tea. The data were analyzed in a completely randomized design with three replications, using SPSS software version 24 and the mean comparison was performed using Duncan's multiple range test. The results showed that with decreasing the amount of chicory, the amount of brix and the activity of probiotic bacteria increased, while decreasing the amount of pickled potatoes and garlic decreased the amount of brix and the activity of probiotic bacteria. Also, with decreasing the amount of chicory, garlic and jerusalem artichoke, the amount of turbidity, PH, antioxidant compounds and antioxidant capacity decreased. The amount of chicory, garlic and jerusalem artichoke did not affect the sensory properties (taste, color and smell) of the drinks. The treatment containing 20% chicory, 1% garlic and 20% jerusalem artichoke had the best chemical, sensory and microbial properties and was introduced as the superior treatment. [ABSTRACT FROM AUTHOR]

Functional drinks can be made from local herbal ingredients that are often used for spices such as cinnamon (Cinnamomum burmanni) and cardamom (Amomum compactum). The purpose of this study is to determine the best formulation of cinnamon and cardamon as a herbal drink based on moisture content, ash content , and sensory evaluation. Raw materials were dried at 50 °C until reached a maximum moisture content 10% and were reduced in size. The formulations were made of comparison between cinnamon and cardamom which were A (100: 0)%; B (80:20)%; C (60:40)%; D (50:50)%; E (40:60)%; F (20:80)%; and G (0: 100)%. The moisture content of all formulas is between 7.12-7.33% (

Abstrak Minuman herbal merupakan minuman berbahan dasar bagian tumbuhan yang berkhasiat bagi tubuh. Salah satu tumbuhan berkhasiat yang dapat diolah menjadi minuman herbal yaitu cabe jawa, namun selama ini cabe jawa hanya digunakan sebagai bahan pembantu dalam pembuatan jamu dan minuman herbal lainnya. Oleh karena itu, terdapat peluang pengembangan produk berbasis cabe jawa sebagai bahan baku utama. Penelitian ini bertujuan untuk mengetahui alternatif pengembangan produk minuman herbal berbasis teh cabe jawa mengunakan metode Value Engineering dengan 5 tahapan, yaitu tahap informasi, kreatif, analisis, pengembangan, dan rekomendasi. Penelitian ini menghasilkan 5 alternatif pengembangan produk minuman herbal berbasis cabe jawa dengan skor tertinggi. Masing-masing alternatif berbeda pada proporsi daun teh dan cabe jawa, berat per kantong, jenis kemasan dan penggunaan benang. Alternatif terbaik yang diperoleh yaitu alternatif 3 dengan kondisi proporsi daun teh dan cabe jawa (1:2) dengan berat < 2 (1-2) gr/ kantong, jenis kemasan box dengan menggunakan benang. Rasio nilai tambah minuman cabe jawa celup dengan metode Value Engineering sebesar 52,095% dengan persentase keuntungan 34,251% dari produk sebelumya dan nilai tambah sebesar Rp5.822,81. Kata Kunci: minuman herbal, teh cabe jawa, Value Engineering Abstract Herbal drinks are drinks based on plant parts that are beneficial for health. One of the beneficial plants that can be processed into herbal drinks is Java long pepper. So far, Java long pepper only used as a supporting ingredient in producing herbs and other herbal drinks. Therefore, there is an opportunity to develop Java long pepper-based products as the primary raw material. This study aims to determine the product development of herbal drink based on Java long pepper tea using the Value Engineering method with five stages (information, creative, analysis, development, and recommendation stages). This study resulted in 5 alternatives for herbal drink products based on Java long pepper tea with the highest score. Each alternative is different in the proportion of tea leaves and Java long pepper, weight per bag, type of packaging, and use of teabag yarn. The best alternative obtained is alternative 3 with the condition of the proportion of tea leaves and Java long pepper (1: 2) with a weight of

The present study assessed the human health risk of metals in selected drinks from Abeokuta, southwestern Nigeria. Fifteen different brands of drinks (alcoholic, non-alcoholic, herbal and non-herbal) were purchased from notable markets in Abeokuta between June and August, 2018. A total of sixty drink samples were analysed for metals using atomic absorption spectrophotometry. Data were subjected to descriptive and inferential statistics. Human health risks were assessed for cancer risk (CR) and non-carcinogenic indices of hazard quotient (HQ) and hazard index (HI). Results showed acidic medium for most of the samples ranging from 3.12 ± 0.29 to 6.14 ± 0.17. The highest concentrations of Fe (5.53 ± 2.81 mg/L) and Mn (6.63 ± 8.33 mg/L) were found in Kunnu and Zobo, respectively. The HQ and HI values of Cu in bottled water indicated non-carcinogenic adverse effects, while the CR of Co in bottled water and bitters demonstrated carcinogenic effects. Regular monitoring of metals in drinks from the study area is recommended. [ABSTRACT FROM AUTHOR]

Several herbal beverages claim medicinal benefits due to their antioxidant properties. However, operational factors such as the extracted herbal component, preparation method or concentration levels, might influence their biological activity. To assess this effect, the antioxidant activity of beverages prepared with Camellia sinensis, Aspalathus linearis or Cochlospermum angolensis, used solely or mixed with different fruit, plant or algae extracts, was studied using different formulations (bags, leaves, roots, granulates, powders, liquids) and different preparation methods (infusion, solubilisation or promptly used). The DF50 (dilution factor responsible for 50% of antioxidant activity) values were calculated to compare their antioxidant activity. A linear discriminant analysis was used to categorize the assayed samples according to their antioxidant activity and bioactive molecules profiles. The results indicated that antioxidant activity and antioxidant compounds are significantly affected by formulation and preparation method, but overall the labelled antioxidant benefits were validated. Green tea showed the highest activity, but with different behaviour within each used formulation. The high DF50 values calculated for some products might be used to adjust the dietary dose or formulation, preventing also putative pro-oxidant effects. Hence, the obtained results might be useful to define the formulation of these highly consumed herbal beverages, enhancing their health effects.

Ethnopharmacological relevance There is very limited information regarding medicinal plants used by traditional healers in Pakistan, for treating wide-ranging diseases. Current study provides significant ethnopharmacological information, both qualitative and quantitative on medical plants in Pakistan and the pharmacological importance of herbal drinks, especially in the discovery of new drugs. Materials and methods The current ethnomedicinal field study was conducted from various traditional communities of Pakistan to document usage of medicinal plants as herbal drinks. Data was collected through field interviews from local people and using semi-structured questionnaires. Data was analyzed using quantitative indices such as UV (use value), RFC (Relative frequency of citation), and FL (Fidelity level). Results The present study recorded 217 plant species belonging to 174 genera and 69 families used in herbal drinks preparations. Major herbal preparations include decoctions, infusions and juice. According to use reports, significant species were Aloe vera , Artemisia fragrans , Allium cepa , Senegalia catechu , Alternanthera sessilis , Malva ludwigii , Arnebia benthamii , Cichorium intybus , Coccinia grandis , Dalbergia sissoo . Major ailment treated with herbal drinks include heartburn, fever, diarrhea, hypertension, and others. Use value (UV) varies from 0.23 to 0.02, with Mentha arvensis (0.23) having the highest value of UV followed by Mentha longifolia (0.22), Plantago lanceolate (0.19), Achillea millefolium (0.18), Coriandrum sativum (0.18), Justicia adhatoda and Malva sylvestris (0.17). Values of RFC varies from 0.28 to 0.09 while Fidelity level (FL) among plants varies from 37.5 to 100. Alternanthera sessilis , Oxytropis lapponica , Millettia pinnata and Salvia bucharica had the highest FL value (100). Conclusion The use of medicinal plants is prevalent in traditional communities of Pakistan. Different herbal preparations are in common practice including various herbal drinks a common tradition and much favoured herbal preparation in terms of its results and regarded as reciprocal to modern drugs. Therefore, suggesting further pharmacological, phytochemical evaluation for essential metabolites and chemical constituents. [ABSTRACT FROM AUTHOR]

Ethnopharmacological relevance Loloh are herbal drinks produced and consumed exclusively in Bali (Indonesia) to prevent and treat different ailments. This is the first study to document plants species used as Loloh , reporting the phytochemical components and pharmacological properties of the most cited plants. Documenting the plants used in herbal drinks in Bali by local communities to treat various ailments (providing some information on phytochemistry and pharmacology of the most interesting plants). Materials and methods Ethnobotanical data were obtained through semi-structured interviews (individual and group discussions) and questionnaires. Plant specimens were collected, identified and made into herbarium vouchers. Results A total of 51 plants species (belonging to 32 families) have been documented for their use in the various preparation of Loloh . Different plants and plant parts are used to prepare Loloh to treat heartburn, fever, diarrhea, hypertension, aphthous stomatitis (canker sores), and other minor health problems. These plants are mainly prepared as decoctions, are juiced or simply added to the preparation. The most cited plants (>30 informants) are Alstonia scholaris (L.) R. Br., Blumea balsamifera (L.) DC., Cinnamomum burmanni Nees ex Bl., and Piper betle L. These plants are well studied with multiple demonstrated pharmacological activities (e.g., antimicrobial, anticancer, antidiabetic). Conclusion The Balinese communities still preserve a rich ethnobotanical knowledge. Several species are well known for their pharmacological properties, but some [such as Pneumatopteris callosa (Blume) Nakai and Dendrocnide stimulans (L. f.) Chew] are understudied and could be promising candidates for further research. [ABSTRACT FROM AUTHOR]

Several herbal beverages claim medicinal benefits due to their antioxidant properties. However, operational factors such as the extracted herbal component, preparation method or concentration levels, might influence their biological activity. To assess this effect, the antioxidant activity of beverages prepared with Camellia sinensis, Aspalathus linearis or Cochlospermum angolensis, used solely or mixed with different fruit, plant or algae extracts, was studied using different formulations (bags, leaves, roots, granulates, powders, liquids) and different preparation methods (infusion, solubilisation or promptly used). The DF50 (dilution factor responsible for 50% of antioxidant activity) values were calculated to compare their antioxidant activity. A linear discriminant analysis was used to categorize the assayed samples according to their antioxidant activity and bioactive molecules profiles. The results indicated that antioxidant activity and antioxidant compounds are significantly affected by formulation and preparation method, but overall the labelled antioxidant benefits were validated. Green tea showed the highest activity, but with different behaviour within each used formulation. The high DF50 values calculated for some products might be used to adjust the dietary dose or formulation, preventing also putative pro-oxidant effects. Hence, the obtained results might be useful to define the formulation of these highly consumed herbal beverages, enhancing their health effects. [ABSTRACT FROM AUTHOR]

Objectives: This investigation aimed to compare caffeinated gums with two different dosages of caffeine (200mg vs. 300mg) by assessing their effectiveness on the improvement of cognitive functions among Iranian individuals voluntarily suffering from 30 hours of sleep deprivation., Material and Methods: Thirty-four healthy male volunteers with ages from 28 to 35 years old were randomly assigned to either 200 or 300mg caffeine intake. Each participant completed CANTAB subtests to assess their core cognitive functions including MOT, RTI, RVP, and SWM before and after sleep deprivation, as well as after being treated with caffeinated gum., Results: The 300mg caffeine intake group indicated higher levels of enhancement of core cognitive functions compared with those in the 200mg caffeine intake group., Conclusion: This study suggests that the dose of 300mg of caffeine could effectively enhance the cognitive functions of Iranian individuals suffering from sleep deprivation.