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Copyright of Neurologie Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pediatrie pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Beta-blockers are used for a wide range of cardiovascular diseases (CVD) - from arterial hypertension to heart failure. Recently, however, a number of analyzes and information have appeared that question the role of beta-blockers in some indications. We provide an overview of the controversies that have arisen around beta-blockers in the treatment of heart failure, hypertension, arrhythmias, in the secondary prevention of ischemic heart disease, and in perioperative administration to patients during non-cardiac operations. [ABSTRACT FROM AUTHOR]

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The definition and diagnostics of prehypertension (PHT), hypertension (HT) and their prevalence in children and adults are presented. Attention was drawn to the PHT and HT programming already in the prenatal and early postnatal period. An overview of very high salt consumption in the Czech Republic and in the world which is connected with PHT, HT and later with complications of cardiovascular diseases (CVD). The concept of salt sensitivity/ resistance is explained. Briefly presented are opinions on the pathophysiology of hypertension. Summarized are the facts about salt consumption in history and the present and possibility of CVD prevention. Recently, the risk of PHT/HT is currently associated with the increasing incidence of overweight/obesity in children and adolescents, who are often associated with high consumption of not only salt, but also sugar. Summarized are principles of primary prevention of PHT/HT and complications of CVD with emphasis on early non-pharmacological intervention. Prevention of PHT/ HT should start already at the age when the individual health care is provided by pediatricians. [ABSTRACT FROM AUTHOR]

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Posterior reversible encephalopathy syndrome (PRES) is a rare pathological entity, in which the neuroimaging, especially MRI, is essential for the diagnosis. The disease is characterized by the typical distribution of cerebral vasogenic edema. Several risk factors are known to be associated with the PRES development. This case report describes PRES in a 46-yearold woman treated in the past for acute myeloid leukemia with numerous concomitant complications. The clinical manifestations of PRES is usually sudden and include a various neurological symptoms. The presence of uncontrolled hypertensive disease is a frequent finding. The treatment of PRES usually focusses on the underlying disease. Although the prognosis of the PRES is generally considered to be favorable, the disease may not be completely reversible and may also be fatal. [ABSTRACT FROM AUTHOR]

Copyright of Remedia is the property of Medical Tribune CZ, s.r.o. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pediatrie pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pediatrie pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pediatrie pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pediatrie pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pediatrie pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Praktické Lékárenství is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pediatrie pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina Sportiva Bohemica et Slovaca is the property of Ceska spolecnost telovychovneho lekarstvi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Remedia is the property of Medical Tribune CZ, s.r.o. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Currently, the Czech Republic, like most other Western countries, is affected by the pandemic of COVID‑19, caused by the SARS‑CoV‑2 virus. Studies to date did not show increased risk of developing COVID‑19 or greater severity of its course with medication of renin‑angiotensin system inhibitors. Patients taking angiotensin converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) should continue treatment with these products, including during hospitalization for COVID‑19. We should continue to follow the current guidelines for the treatment of arterial hypertension. The goal office blood pressure is <140/90 mm Hg for all hypertensive patients, in case of good tolerance of treatment around 130/80 mm Hg or lower. In pharmacotherapy we prefer the combinations of an ACE‑inhibitor or angiotensin receptor blocker with a calcium channel antagonist and/or a diuretic, beta blockers remain reserved for specific indications. In most patients, combination therapy should be initiated from the beginning of treatment, optimally in the form of a fixed drug combination. We should reach goal blood pressure within 3 months of starting treatment. [ABSTRACT FROM AUTHOR]

Copyright of Medicina Sportiva Bohemica et Slovaca is the property of Ceska spolecnost telovychovneho lekarstvi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Praktické Lékárenství is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pediatrie pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina Pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Ischemic strokes are frequent neurological diseases. Annual incidence in Europe varies from 100 to 350/100.000 inhabitants per year. Strokes are leading cause of long-term invalidity and 3rd cause of death worldwide. Reperfusion therapy represents therapeutic keystone. In the year 2015, positive results of five randomized studies showed the superiority and efficacy of mechanical thrombectomy compared to standard treatment in acute ischemic stroke due to large vessel occlusion. Positive results of DAWN and DEFUSE-3 trials published in 2017/2018 showed benefit for endovascular therapy beyond standard therapeutic time window in strictly selected patients based on imaging of ischemic penumbra using CT perfusion or MRI. Thus, "tissue" window is becoming a limiting factor for mechanical thrombectomy now instead of previous "time" window. Use of aspiration thrombectomy and choice of suitable anesthesia caused increase of procedural efectivity of intervention. There are 3 possible positive outcome predictors which can be influenced in acute care. Blood pressure seems to be the key variable in acute phase. Lowering the values is associated with better outcome up to systolic blood pressure under 100 torr where growth of complications is observed. Oxygen stress protective effect of normoglycaemia appears to be more important in case of mechanical thrombectomy. Body temperature seems to be good predictor of outcome in relation to other characteristics of the patient. Its' sole decrease via therapeutic hypothermia is in the cases of acute ischaemic stroke associated with significantly higher incidence of severe complications. [ABSTRACT FROM AUTHOR]

Copyright of Remedia is the property of Medical Tribune CZ, s.r.o. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Hyperactivity of the sympathetic nervous system as a pathophysiological cause can occur in all age categories and stages of hypertension, but it most often occurs in younger people. This con‑dition has a characteristic clinical and laboratory finding and is one of the indications for the administration of a beta‑blocker in the first choice. The case report describes a typical case of a young man with newly diagnosed hypertension and sinus tachycardia, diagnostic balance and initiation of treatment. [ABSTRACT FROM AUTHOR]

Hypertension is a serious cardiovascular risk factor, and because of its high incidence in adults (30-40 %), its treatment is also a major medical and economic problem. Sympathicotonia plays a key role in the etiopathogenesis of hypertension. Currently, pharmacotherapy is the mainstay of hypertension treatment. Historically, however, the first truly effective treatment of hypertension, including malignant hypertension, was surgical sympathectomy. Unfortunately, surgical sympathectomy was often complicated by serious or fatal complications, and was abandoned with the advent of modern pharmacotherapy. Catheter-based renal denervation is based on the concept of mini-invasive partial renal sympathectomy. Introduced for the first time in 2009, renal denervation has undergone its historical development: from inadequate initial euphoria to subsequent rejection to contemporary renaissance. Currently, renal denervation appears to be an effective adjunctive non-pharmacological treatment in a selected group of patients with true primary resistant hypertension, in whom "maximum combined pharmacotherapy alone" fails to achieve target blood pressure levels. [ABSTRACT FROM AUTHOR]

This article refers to two different but at the core maybe the same ceses of patients with type 2 diabetes mellitus and the accumulation of other risk factors. Highlights the significant potentiation of cardiovascular risk in a diabetic patient with hypertension and dyslipidemia and trying to highlight the right choice of targeted medication which, on the one hand, affects cardiovascular risk and, on the other, improves patient treatment compliance. [ABSTRACT FROM AUTHOR]

Copyright of Interní Medicína pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

ACE inhibitors and beta-blocking agents have an irreplaceable role in various indications in cardiology, including hypertension, heart failure, secondary prevention in coronary heart disease, especially after acute coronary syndromes. They can be successfully used in other indications, too. Patient prognosis can be influenced at various levels, which however means higher numbers of drugs used. In recent years, we have witnessed trends in drug manufacturers to bring to the market pills with two or three complementary substances. One of them – a fixed combination of a beta-blocking agent and an ACE inhibitor – is unique and its name is COSYREL®. [ABSTRACT FROM AUTHOR]

Turner syndrome (TS) is the most common chromosomal disorder in women, which is caused by absence or structural abnormality of X chromosome. The most common features of TS are short stature, gonadal dysgenesis and congenital heart and kidney diseases. Spectrum of congenital heart diseases is highly varied and most often the left side of the heart is affected. Bicuspid aortic valve and coarctation of the aorta are the most frequent of them. Authors present case reports of four patients with TS and the anomaly of the aortic arch but with clinically different manifestation and a brief overview of this topic. [ABSTRACT FROM AUTHOR]

Copyright of Interní Medicína pro Praxi is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The article provides an overview of the effects of massage at various diagnoses and clinical states. The positive effects of massage on the human body are documented by many studies. It is advisable to indicate massage as a complementary procedure, or as a preparation for more specific and effective methods of therapy. A review of proven mass effects outlines a wide range of uses. The author of this article, however, sees methodological reserves in some experiments in which the massage was used. Therefore, he supports the view of some authors of meta-analyzes stressing the tightening of the methodologies of such thematic studies. [ABSTRACT FROM AUTHOR]

Turner syndrome (TS) is the most common chromosomal disorder in women, which is caused by absence or structural abnormality of X chromosome with classical traits that include growth retardation, gonadal dysgenesis and infertility. Acquired cardiovascular disease is a major cause of premature morbidity and mortality in TS. Congenital heart disease and acquired cardiovascular disease can reduce life expectancy by up to 13 years. Ischemic heart disease, stroke and aortic dissection belong to acquired cardiovascular disease with high prevalence. This review is focused on issues of risk factors for acquired cardiovascular disease such as arterial hypertension, glucose metabolism disorders, dyslipidemia and obesity in patients with TS. The main point of this review is arterial hypertension, its prevalence in TS, diagnostic and appropriate therapeutic approaches. [ABSTRACT FROM AUTHOR]

Copyright of Klinická Mikrobiologie a Infekční Lékařství is the property of TRIOS, spol. sr.o. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aim: The aim of our study was to establish whether or not renal sympathetic denervation (RSD) may help control blood pressure (BP) levels in patients with severe hypertension refractory to pharmacological therapy. Method: Out of a group of 12 patients, candidates for RSD, with uncontrolled hypertension (systolic BP over 190-200 mm Hg on repeated measurements despite optimal medication) four patients were excluded for multiple renal arteries and one for hyperaldosteronism. Seven patients had RSD using a Symplicity device (5 M, 2 F) with a mean age of 64.9 years. While all were followed up for a minimum of 6 months, follow-up duration in the majority of them was substantially longer (12-20 months). Results: At six months post-RSD, six of the seven patients showed a decrease in systolic BP by at least 20 mm Hg while receiving the same or fewer doses of antihypertensive agents. A similar response was seen in diastolic BP. The BP decrease was maintained throughout whole follow-up. Conclusion: In a small group of patients we demonstrated that renal sympathetic denervation is capable of reducing blood pressure even in patients with severe hypertension. [ABSTRACT FROM AUTHOR]