1. Use of edoxaban in clinical practice. The ETNA-AF-Europe registry. Comparison with data from Spain
- Author
-
Baron-Esquivias G, Rabadan I, Quintana A, Cerezo Manchado J, Miranda I, Gomez-Barrado J, Paredes M, Santas E, Rodriguez J, Munoz-Robles J, Oliver-Minarro D, Santamaria A, and investigators of ETNA AF Spain
- Abstract
Aim: To ascertain the clinical profile and management of edoxaban in clinical practice. Materials & methods: Prospective, noninterventional postauthorization study of nonselected patients with atrial fibrillation treated with edoxaban from 12 European countries. Patients' baseline characteristics are presented. Results: A total of13,638 patients (73.6±9.5years; 76.6/23.4% edoxaban 60/30mg; CHA2DS2-VASc 3.1; 838 [6.1%] from Spain) were included. In Spain, the percentage of very elderly and fragile patients was greater and the risk of thromboembolism (CHA2DS2-VASc =2, 98.0 vs 87.3%; p < 0.001) and bleeding (HAS-BLED, 3.2 vs 2.7; p < 0.001) was greater in patients treated with edoxaban 30mg. The proportion of patients taking edoxaban 30mg was similar than in ENGAGE AF-TIMI 48. Conclusion: In Spain, patients treated with edoxaban were older and fragile.
- Published
- 2020