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Copyright of Turkiye Klinikleri Journal of Nursing Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Pruritus, defined as an unpleasant sensation that compels scratching, is a common occurrence in dermatological disorders. Chronic pruritus is defined as itching that persists for a period exceeding six weeks. Lichen simplex chronicus (LSC) is a chronic dermatological condition that presents with dry, scaly, and thickened skin lesions, which typically arise from habitual scratching. Additionally, paraneoplastic pruritus may serve as an early indicator of the presence of solid tumours. This case report outlines the diagnostic and therapeutic process of a 73-year-old male diagnosed with lichen simplex chronicus (LSC), confirmed by skin biopsy. Subsequent malignancy screening revealed the presence of solid nodules in the lungs and multiple metastatic masses in the liver. Biopsies of the lung nodule and liver mass demonstrated positivity for TTF-1 and synaptophysin, leading to a diagnosis of mixed component lung adenocarcinoma and small cell lung cancer. In order to ascertain the underlying cause of the patient's chronic itching, a comprehensive investigation was conducted, which considered a range of potential factors, including haematological diseases, endocrine disorders, liver diseases, infections, drug-related factors, and neurological and psychiatric causes. Despite a comprehensive evaluation, the precise etiology of the chronic itching remained elusive. The initiation of carboplatin and etoposide therapy for lung cancer resulted in a significant reduction in the patient's itching, which may suggest a possible link between chronic itching and malignancy. Unfortunately, the patient succumbed to hypoxia, pneumonia, and multiple organ failure two months post-diagnosis. This case serves to illustrate the potential of chronic pruritus as a symptom of cancer. While paraneoplastic pruritus is often associated with haematological malignancies, this report highlights that it can also occur with solid tumours. It is important for clinicians to be aware of this potential association, as it allows for timely diagnosis and treatment. [ABSTRACT FROM AUTHOR]

Copyright of Medical Journal of Ankara Training & Research Hospital is the property of Medical Journal of Ankara Training & Research Hospital and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bagcilar Medical Bulletin / Bağcılar Tıp Bülteni is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Ahi Evran Medical Journal is the property of Ahi Evran University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Tarih İncelemeleri Dergisi is the property of Tarih Incelemeleri Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Agri: Journal of the Turkish Society of Algology / Türk Algoloji (Ağrı) Derneği'nin Yayın Organıdır is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Atopic dermatitis (Ad), an important dermatological problem for humans, similar to dogs. Although it is known that leaky gut-related increase in intestinal permeability and deterioration of the intestinal microbiota play a role in the disease, there are still unknowns regarding in term of both diagnosis and treatment. In this study, based on the relationship between atopic dermatitis and intestinal microbiota; 1) determination of whether Lactobacillus plantarum and Lactbacillus paracasei and probiotic enema can be used in the treatment of itching, which is the leading symptom, 2) aimed to evaluate the administration of one of the new, up-to-date probiotherapy options that are promising for role model treatment by rectal enema, also known as proctolysis, in contrast to problems of absorption in oral administration. In our study, a total of 12 dogs with Ad as different ages, breeds, and both sexes were included. Cases which had no previous treatment history, showed clinical findings compatible with Favrot criteria and atopy accompanying with increasing allergen-specific IgE level, were determined in the light of allergen-specific IgE levels (before treatment), CADESI-04 scores and clinical findings, and then rectal enema with nutraceuticals. Probiotic enema with Lactobacillus plantarum and Lactbacillus paracasei was applied 10-15 cm forward from the rectum via foley catheter or rectal catheter. Pruritus of 12 dogs with Ad applied probiotherapy by rectal enema were ceased significantly between 0 and 10 days. In conclusion, it has been observed that L. plantarum and L. paracasei strains, which can be evaluated in antipruritic lactic acid bacteria, can be used for both clinical improvement and relief of itching in dogs with atopic dermatitis at the recommended and applied dose/time in this study. [ABSTRACT FROM AUTHOR]

Objective: Intrahepatic Cholestasis of Pregnancy (ICP) is a pregnancy complication characterized by pruritus, elevation in liver enzymes and concentration of serum bile acids (SBA). In the current study, we aimed to investigate the relationship after treatment of ursodeoxycholic acid (UDCA) in patients with ICP between pruritus and the level of alanine aminotransferase (ALT) and SBA. Methods: A total of 30 pregnant diagnosed with ICP in the Gastroenterology outpatient clinic of Kanuni Sultan Süleyman Training and Research Hospital were enrolled in the study in 2018. Data including patient age, pregnancy week, delivery week, pruritus score, level of SBA and ALT levels were recorded. Results: The mean age of pregnant was 29.9±6.5 and the mean week of pregnancy was 31.8±3,74. There was no significant difference in terms of ALT level between before and after period of UDCA treatment (106.13 ± 91.27 vs. 45.8 ± 35.76 U / L, p = 0.87, respectively). A significant difference was observed in terms of ALT level between postpartum period and post-UDCA treatment (22.2 ± 5.79 vs. 45.8 ± 35.76 U / L, p = 0.002, respectively). There was a significant difference in terms of visual analog scores between before and after period of UDCA treatment (6.6 ± 1.44 vs. 2.03 ± 1.49, p = 0.02, respectively). Conclusion: The treatment of UDCA in ICP positively effects on level of pruritus, but does not contribute to regression of ALT level. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Academic Research in Nursing (JAREN) is the property of Hemsirelikte Egitim ve Arastirma Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Two medicinal plants, Curcuma longa (turmeric) and Nigella sativa (black cumin), have generated growing interest for their therapeutic antiinflammatory action. We hypothesize that commercially available topical C. longa and N. sativa cream (Dermacumin cream®) will significantly decrease both the Feline Dermatitis Extent (FDE) and Severity Index (SI) and the pruritus scores after 3 weeks of twice-daily treatment of feline head and neck dermatitis. Ten client-owned cats with feline head and neck dermatitis which had received no previous treatment. FDE and SI scores gradually decreased on days 7 (P<0.001) and 28 (P<0.0001) compared to day 0. Similarly, decreased Visual Analog Scale (VAS) scores were detected on days 7 and 28 (P<0.0001). Cats receiving the herbal cream for 3 weeks all had significantly decreased FDE and SI scores, from 171.8 to 0 (P<0.0001), and VAS scores from 6.3 to 0 (P<0.0001). A positively elevated correlation (r=0.62, P<0.001) between FDE and SI and VAS scores for each case through evaluation period was revealed. The present study supports a potential benefit of topical herbal medicine against feline head and neck dermatitis. [ABSTRACT FROM AUTHOR]

Introduction: Pruritus is a common symptom that has dermatologic, systemic, neurological, psychogenic, mixed, and unknown causes. The aim of this study was to identify the underlying origin of pruritus (UOP) in hospitalized patients having intractable pruritus and presenting with secondary scratch lesions (SSLs) and to assess the factors affecting UOP. Methods: Data of 95 patients (male/female: 47/48) presenting with SSLs were examined retrospectively. Demographic and clinical characteristics, diagnostic procedures, and treatment agents were recorded. UOP was defined as dermatological and non-dermatological factors. Results: The median (range) age and disease duration were 61 years (11-91) and 2 months (0.06-120), respectively. Pruritus was related to dermatological and non-dermatological reasons in 78% and 22% of patients. Univariate analysis revealed that factors showing an association between patients with and without underlying dermatological origin of [pruritus (UDOP)] were age, disease duration, disease onset, ≥3 months of continuous drug use, intake of drugs attributed to lead to pruritus, accompanying systemic diseases, polypharmacy, renal function tests, and the presence of sleep disorders (p=0.001, p=0.001, p=0.001, p=0.03, p=0.045, p=0.02, p=0.004, p=0.047 and p=0.01, respectively). Multivariate analyses revealed that acute onset of pruritus increased the risk of UDOP by 15.28 times (p=0.005, 95% confidence interval (CI): 2.30-101.67) compared to patients with chronic onset. The lack of sleep disorders increased the risk of UDOP by 8.22 times (p=0.01, 95% CI: 1.67-40.56) compared to patients who had sleep disorders. Conclusion: Acute onset of pruritus and lack of sleep disorders were independent predictors of UDOP in patients with SSLs. The remaining patients without UDOP should be directed to the relevant departments for accurate diagnosis and management. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Physical Medicine & Rehabilitation Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Primary biliary cholangitis (PBC) is a slowly progressive chronic cholestatic granulomatous liver disease of unknown etiology, mostly affected by middle-aged women, accompanied by damage to the small bile ducts. PBK can cause serious diseases such as portal hypertension or liver failure and then progress to cirrhosis. As in this case, it should not be forgotten that it may come with non-specific symptoms, detailed history and diagnosis should be confirmed with necessary laboratory tests in patients suspected. [ABSTRACT FROM AUTHOR]

Pruritus is an unpleasant sensation which is found in various dermatologic and systemic diseases. Dermatological investigation is mandatory in conditions with dermal lesions. Severe systemic disorders may be found in patients with pruritus without dermal lesions. For this reason, after a through medical history and examination, laboratory and radiological examinations may be required. [ABSTRACT FROM AUTHOR]

Dış kulak yolu yabancı cisimleri hemen her gün kulak burun boğaz uzmanları tarafından karşılaşılan bir acil sorundur. Yabancı cisimler işitme kaybı, ağrı, şiddetli kaşıntı, kulak akıntısı, çınlama ve baş dönmesine neden olabilir. Aynı zamanda yabancı cismin çıkarılması sırasında da komplikasyonlar açısından büyük riskler vardır. 82 yaşında demans hastalığı olan ve işitme kaybı, ağrı, şiddetli kaşıntı, kulak akıntısı rahatsızlığı çeken erkek hasta kliniğimize acil vaka olarak yönlendirildi. Otoskopik muayenesinde her iki kulakta metalik olmayan beyaz/sarımsı renkte pamuksu görünümü olan yabancı cisimler tespit edildi. Tüm pamuk yabancı cisimler cerrahi odasında herhangi bir anestezik ilaç kullanmaksızın aligatör yardımıyla çıkarıldı. Kulakta yabancı cisim olan hastalara yaklaşım komplikasyonların azaltılması ya da ileri hasarların önlenmesi açısından tecrübeli eleman yada KBB uzmanı tarafından uygun ekipman kullanılarak yapılmalıdır.

Copyright of Turkish Journal of Dermatology / Turk Dermatoloji Dergisis is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Inflammatory linear verrucous epidermal nevus (ILVEN) is usually accompanied by persistent and severe pruritus. It is mostly located in the lower left limb as hyperpigmented or erythematous hyperkeratotic linear papules and/or plaques. Genital/perigenital involvement is extremely rare. It varies in size from very small lesions to the involvement of the whole extremity. The differential diagnosis is broad, including but not limited to lineer psoriasis, lichen striatus, verrucous epidermal nevus, lichen simplex chronicus, linear lichen planus and linear Darier disease and, prognosis is poor. In this report, we present a case of vulvar ILVEN that responded to topical nonsteroidal anti-inflammatory cream. [ABSTRACT FROM AUTHOR]

Tüm insanlar hayatlarında bir kez de olsa pruritusu yaşamışlardır. Akut kaşıntı, böcek ısırması gibi, saniyelerden haftaya kadar değişen sınırlı süre kaşıntı yaşanmasıyken, kronik kaşıntı ise 6 haftadan uzun kaşıntılara verilen addır. Kronik pruritus dünya genelinde bir problemdir. Her yaşta görülebilir ve yaşam kalitesine büyük etkisi vardır. Kaşıntı için akut ve kronikten başka sınıflamalar da vardır. IFSI (International Forum for the Study of Itch: Kaşıntı Çalışması Uluslararası Forumu) sınıflaması kaşıntılı bireyleri 3 gruba ayırır; hastalıklı deride kaşıntısı olanlar (grup 1), hastalık olmayan deride kaşıntısı olanlar (grup 2), deri kaşıma lezyonlarına sekonder kaşıntısı olanlar (grup 3). Ayrıca altta yatan kaşıntılı hastalıklara göre de 6 spesifik kategoriye ayırır: dermatolojik, sistemik, nörolojik, psikojenik, miks ve diğer pruritus.

Prurigo pigmentosa is a rare skin disease of unknown etiology. Prurigo pigmentosa is seen frequently in young Japanese women. It is characterized by pruritic, erythematous macular, papular, papulovesicular lesions and reticular pigmentation. Lesions often localize back, neck, and chest. Dapsone and minocycline are most commonly used in the treatment of prurigo pigmentosa. Here we report a 19 years-old women diagnosed with prurigo pigmentosa by clinical and histopathological findings and treated with doxycycline. Effectiveness of doxycycline in the treatment of prurigo pigmentosa was discussed in the light of literature. [ABSTRACT FROM AUTHOR]

Progressive familial intrahepatic cholestasis (PFIC) has a significant place among the childhood cholestasis. It is the second most frequent liver transplant indication met in some liver transplant institutions. It constitutes approximately 10-15% of all cases of cholestasis and liver transplant. PFIC is an autosomal recessively inherited disorder and causes hepatocellular-originated cholestasis. In the period from infancy to adulthood it may cause death due to liver failure. PFIC has three types and the most frequently observed clinical symptoms of all three types are; pruritus, hepatitis, growth retardation, hepatomegaly, and splenomegaly. The prognosis of these three types of PFIC is different. The complications of PFIC are; portal hypertension, liver failure, cirrhosis, hepatocellular carcinoma, and extrahepatic symptoms. Although medical and surgical treatments are applied in order to improve the patients' life quality, most of the cases require liver transplantation in the early stage. [ABSTRACT FROM AUTHOR]

Imatinib mesylate is a small-molecule tyrosine kinase inhibitor (TKi) designed to target c-ABL and BCR-ABL, approved for the treatment of chronic myeloid leukemia and gastrointestinal stromal tumors. Adverse cutaneous reactions induced by imatinib are frequent, generally moderate, and dose-dependent. The aim of this work was to investigate the possible contribution of interleukin (IL)-33 and IL-31, cytokines involved in disorders associated with itching, in the pathogenesis of pruritus in a patient undergoing imatinib mesylate treatment. His IL-31 and IL-33 serum levels were significantly higher than in the control group (respectively 96.6 pg/mL vs. 7.623±7.681 pg/mL and 27.566 pg/mL vs. 6.170±7.060 pg/mL). In light of these findings, imatinib mesylate-related symptoms of dermatologic toxicities might be related to the release of IL-31 and IL-33. In particular, it is supposable that TKi usage could cause keratinocyte injury, the release of IL-33, and the consequent interaction with its receptor on mast cells that induces the secretion of several factors capable of causing skin manifestations, including IL-31, a known pruritus-inducing cytokine. This report, to the best of our knowledge, is the first work describing the possible involvement of the IL-31/IL-33 axis in the pathogenesis of skin side effects related to imatinib mesylate treatment. [ABSTRACT FROM AUTHOR]

Copyright of Turkish Journal of Dermatology / Turk Dermatoloji Dergisis is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Foreign bodies in the external canal of the ear are an emergency problem encountered by the otolaryngologist almost every day. Foreign bodies may cause hearing loss, pain, severe itching, ear discharge, tinnitus and vertigo. There is also great risk for complications during the removal of foreign bodies. An 82 years old male patient with dementia suffering from hearing loss, pain, itching and ear discharge in both ears was referred to our clinic as an emergency case. Otoscopic examination revealed multiple nonmetallic foreign bodies, whitish/yellowish cottony material, at both ears. All cotton foreign bodies were removed with alligator in the surgery room without use of any anesthetic agents. The management of patients with ear foreign bodies must be carried out by the otorhinolaryngologist or skilled professional with the use of suitable material to minimise complications or prevent further damages. [ABSTRACT FROM AUTHOR]

Itching is a situation which has biological, psychological and sociological dimensions, accrue as a multidimensional symptom in many diseases, especially in skin diseases. Management of effective itch should be considered pharmacologic and nonpharmacologic as complementary methods. Researches shows that, nonpharmacologic methods are reduced using drugs related to itching and the severity of itching. One of the roles of health professionals is to advise individuals, who are living on this problem, using the nonpharmacologic methods in checking the itching. In this review, knowledge of current nonpharmacological methods modalities used to itching and checking the itching is summarized. [ABSTRACT FROM AUTHOR]

Objective: Reasons for application to emergency departments may vary, in dermatology as well as in other branches, according to the geographic regions, climatic and socio-cultural structures. The aim of this study is to gain epidemiological knowledge about the identification, clinical features, treatment and follow-up procedures of patients who attended with dermatologic problems to the emergency department of an university hospital in an island with a subtropical climate in Mediterranean area. Materials and Methods: In this retrospective descriptive study, patients who were admitted to the emergency department with a dermatological complaint during an 18-month period between July 2010 and December 2011 in the Emergency Department of Near East University Hospital, Nicosia, TRNC were evaluated. Descriptive statistics were evaluated as mean and percentage. Results: 1.8% (206 of total 11441) of applications to the emergency department were dermatological diseases. Urticaria/angioedema was the most common cause of applications, and was followed by drug reactions, insect bites and cellulitis respectively. Conclusion: Results of our study indicate that the most common reason for application to the emergency department in North Cyprus is urticaria, and this finding is consistent with other studies in the world. However, insect stings are more common and have specific features. [ABSTRACT FROM AUTHOR]

Objectives: We aimed to determine possible changes in pruritus, quality of life, depression and sleep quality in pruritic hemodialysis (HD) patients with gabapentin therapy. Patients and Methods: Fourteen adult HD patients (7 men, 7 women; mean age 59.7±17.2 years; range 41 to 88 years) with history of pruritus of more than eight weeks were assigned to receive 8-week gabapentin (300 mg per day) therapy. The daily pruritus were recorded using visual analogue scale for each period of the study during one week preceding the trial, the active treatment phase, the placebo phase and the intervening 1-week washout period. Sleep quality was determined with a modified post-sleep inventory, quality of life with a short form of Medical Outcomes Study (SF-36), depression using the Beck Depression Inventory. Results: The mean pruritus score and total of post-sleep inventory were decreased significantly with gabapentin therapy (p=0.01 and p=0.002 respectively). Physical and mental component scales of SF-36 increased, whereas cognitive and somatic depression index decreased with gabapentin. Conclusion: We concluded that beneficial effects of gabapentin therapy on pruritus, quality of life, depression and sleep quality are clinically important in HD patients with pruritus. Gabapentin therapy should be taken into account as an important choice of therapy in pruritic HD patients. [ABSTRACT FROM AUTHOR]

Hepatitis A is an acute infectious disease of the liver caused by the hepatitis A virus. Many cases have little or no symptoms. In our case, a nineteen year old female patient referred our hospital because of exhaustion, jaundice and diffuse itching complaints which existed for one week. In dermatological examination, there were diffusely erythematous, excoriated papules with crusts on the body as more significant on the lower extremity. The patient was diagnosed with acute viral hepatitis A and generalized pruritus according to present findings. Cholestyramine 16 g/day and acrivastine tablet as 1x1 were started to administrate for hyperbilirubinemia and itching. The patient whose complaints regressed partially at the eighth day of the treatment was discharged by her own will. Consequently, patients with generalized pruritus who do not have any previous primary cutaneous disorders could be tested for HAV infection. [ABSTRACT FROM AUTHOR]

Copyright of Turkish Journal of Dermatology / Turk Dermatoloji Dergisis is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Tenofovir disoproxil fumarate (TDF) is a potent antiviral drug that has a high genetic barrier. It is used in the treatment of human immunodeficiency virus (HIV) infection and chronic hepatitis B. Termination of the TDF therapy because of side effects is very rare. Pruritus is not taken into account as a reason of termination in the literature. A case of chronic hepatitis B whose treatment was terminated because of pruritus is presented. [ABSTRACT FROM AUTHOR]

Itchiness is the desire for mechanical irritation of the skin and it may result from various dermatological and sometimes neurological diseases. Neurological causes for itch are relatively unknown and frequently overlooked. Here, we report a case of possible acute inflamatory polyradiculopathy who had facial pruritus and diplopia as the initial symptoms. Diagnosis of our patient was delayed because initial diplopia and pruritus complaints were considered as nonspecific and unrelated to the nervous system. We suggest that pruritus may be a remarkable neurological finding especially when it is accompanied by other neurological symptoms. [ABSTRACT FROM AUTHOR]

Creutzfeldc-Jacob's disease is a rare and fatal neurodegenerative disease characterized by the accumulation of abnormal prion-like proteins in the central nervous system. Clinical features, electroencephalography (EEG), magnetic brain resonance imaging (MRI) and protein 14.3-3 is used in diagnosis. Protein 14.3.3 may be negative in the early or late stages of the disease. Presentation with psychiatric symptoms and itching is not typical in the onset of the disease. Here we present a patient who was first admitted to the psychiatry clinic due to his psychiatric symptoms and had severe itching resistant to antihistamine treatment. (Turkish Journal of Neurology 2013; 19:25-7) [ABSTRACT FROM AUTHOR]

Scabies is an infestation caused by Sarcoptes scabiei and characterised by polymorphous lesions that may include burrows, papules, pustules, crusts and excoriations. Several pruritic diseases may be confused with scabies. Herein, we present a case of scabies with lesions resembling perforating folliculitis diagnosed on the basis of both clinical and histopathological view. A 72-year-old man with type 2 diabetes mellitus and receiving hemodialysis for ten years due to end-stage renal disease was admitted to our dermatology department with a 6-month history of severe pruritus. Based on the results of skin biopsy revealing Sarcoptes scabiei in the epidermis, the patient was diagnosed as scabies and was successfully treated with 5% permethrin. This case is presented to emphasize that scabies should be considered in the differential diagnosis in cases of chronic pruritus. [ABSTRACT FROM AUTHOR]