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Emotions shape how people understand and interact with others. Here, we review evidence on the relationship between anxiety—a future-oriented emotion characterized by negative valence, high arousal, and uncertainty—and mentalizing—the ascription of mental content to other agents. We examine three aspects of this relationship: how people with anxiety disorders perform on mentalizing tasks relative to controls; how situational anxiety alters mentalizing performance; and how autistic people, who experience the impacts of mentalizing differences, are at high risk of anxiety. We propose a bidirectional model for understanding how short-term and longer term anxiety are related to mentalizing. Key to this relationship is the aversive experience of uncertainty and the motivations that result from it.

Introduction: The construct of epistemic trust (ET) has gained wide acceptance and support in the field, although there is little empirical evidence to substantiate the theoretical assumed model. Studies of the assessment of ET were conducted in community samples only and the mediating role of attachment and mentalizing in addition to ET was not investigated. This study examines the theoretical assumed relationships between ET and attachment and mentalizing as well as the mediating role of attachment, mentalizing and ET in the association between childhood adversity and borderline personality disorder (BPD) in a heterogeneous sample containing also patients. Methods: The associations between ET and attachment, mentalizing, childhood maltreatment and BPD were explored in a sample of 245 participants, including subjects from the community as well as patients diagnosed with anxiety and personality disorders from two clinical samples. Multiple mediation analysis was performed to explore the mediating role of attachment (ECR-R), mentalizing (RFQ), and ET within the relationship between childhood trauma (CTQ-SF) and BPD (MSI-BPD). Results: Strong relationships between ET and attachment and mentalizing were found indicating that lower degrees of cET are associated with insecure attachment and lower reflective functioning. Attachment, mentalizing, and ET together accounted for 75% of the mediation between childhood adversity and BPD. Hypomentalizing and anxious attachment accounted for the largest share of the mediation. Conclusion: Our findings provide preliminary evidence for the theoretical supposed model of ET and suggest relevance of ET in the mediation between childhood adversity and PDs, although the role of ET seems smaller than assumed by recent theories. [ABSTRACT FROM AUTHOR]

Introduction: This secondary analysis of quality control data assessed principal components of personality dysfunction and their relationship to mentalizing in a sample of treatment-seeking women with severe personality disorders. Methods: The Schedule for Nonadaptive and Adaptive Personality (SNAP) and the Movie for the Assessment of Social Cognition (MASC) were administered to 37 females in routine quality assessments of a specialized residential treatment program. Principal component analysis (PCA) of SNAP scores was used to determine dimensions of personality most significantly contributing to overall maladaptive personality functioning. Bootstrapped stepwise regression tested the relationship of dimensional personality indices to hypermentalizing and hypomentalizing on the MASC controlling for general psychiatric severity. Results: Four principal components (PCs) explained 71.4% of the variance in personality dysfunction, mapping onto antisocial, obsessive compulsive, borderline, and narcissistic personality constellations. The borderline and antisocial PCs were positively predictive of hypermentalizing. The obsessive-compulsive PC was positively predictive of hypomentalizing, while the antisocial PC was negatively predictive of hypomentalizing. Conclusion: The study reiterates prior findings of a relationship between hypermentalizing and borderline and antisocial personality profiles. It also contributes evidence to the limited research on hypomentalizing as a clinical indicator and potential treatment target for obsessive-compulsive personality, and shows evidence of a negative relationship between antisocial personality disorder and hypomentalizing. These findings provide clinical indications for enhancing and regulating mentalizing via attention to and interpretations of internal and interpersonal events in individuals with personality disorders. Further research is needed to replicate these associations in larger, more representative clinical samples. [ABSTRACT FROM AUTHOR]

Objectives Older age is associated with poorer ability to accurately infer mental states, but some mental states are more complex than others. Sarcasm is a complex mental state because the literal and intended meaning of a speaker's words are in opposition. Individuals must rely on additional cues (e.g. facial expressions, intonation) for accurate inference. We hypothesized that understanding of sarcastic versus sincere exchanges would be more sensitive to age-related difficulty in mental state understanding. Methods We examined accuracy at identifying sarcasm among 263 adults (ages 18–90 years) using videos of social interactions in The Awareness of Social Inference Test. Hypotheses were tested using a logistic linear mixed effects model predicting correct/incorrect trial-level responses. To characterize why sarcasm differed with age, we measured 2 abilities commonly implicated in mental state understanding: facial emotion recognition and cognitive performance. Results Sarcasm understanding declined with age, whereas understanding of sincere exchanges did not. Both better emotion recognition and cognitive performance related to better understanding of sarcastic but not sincere exchanges. Only cognitive performance showed an age-related effect such that the cognitive performance among the oldest participants facilitated their understanding of both sarcastic and sincere exchanges. Discussion We showed that individual variation related to age and social and cognitive performance is more pronounced when the use of multiple mental state cues is more (sarcasm) or less (sincerity) necessary for accurate understanding of social interactions. Naturalistic paradigms involving multiple mental state cues can address important questions about how older adults make decisions in the real world. [ABSTRACT FROM AUTHOR]

Epistemic trust—trust in the relevance and utility of social learning—is central to helping processes between clients and workers in helping services. Yet, due to their experiences, clients may adaptively develop predispositions toward stances of epistemic mistrust or epistemic credulity. From an AMBIT (adaptive mentalization-based integrative treatment) perspective, this article argues that epistemic mistrust and credulity are both caused by social injustice and generate further social injustice. Helping services commonly respond in ways that fail to acknowledge this social injustice and, perversely, deliver further injustice still. Our primary focus is how these issues relate to work with clients, but we argue that they are present in work within AMBIT's other foci, too: in teams, multiagency networks, and learning. We conclude that workers and helping services have a moral duty to recognize and attend to the multiple social injustices associated with epistemic mistrust and credulity. [ABSTRACT FROM AUTHOR]

Depression is a very common mental health problem in adolescence. Although over the past decades a number of psychological interventions for depression in adolescence have been developed and empirically evaluated, recent systematic reviews and meta-analyses suggest that there is considerable room for improvement of their effectiveness. This is particularly true for the treatment of adolescents with "complex" depression, that is, those where depression is embedded within broader personality and relational problems, often related to a history of attachment trauma. Mentalization-based treatment (MBT) may be particularly effective in these cases, as it has a strong focus on temporary and long-term impairments in mentalizing (i.e., the capacity to understand the self and others in terms of intentional mental states), which are very typical of adolescents with depression. This article outlines a continuum of severity of depression as seen from a mentalizing perspective, ranging from the mild to moderate to the more severe end of the spectrum. This is followed by a summary of the mentalizing approach to understanding depression along the spectrum of severity, the empirical evidence supporting this approach, and a description of the basic principles of MBT for depression. We close with some thoughts about the future of MBT in the treatment of depression in adolescents. [ABSTRACT FROM AUTHOR]

This article explores the implications of epistemic trust within the mentalizing model of psychopathology and psychotherapy, emphasizing the role of the restoration of epistemic trust in therapeutic settings. At the core of this exploration is the developmental theory of mentalizing, which posits that an individual's ability to understand mental states—both their own and others'—is cultivated through early caregiver interactions. The article expands on this concept by reviewing and integrating evolutionary theories suggesting that humans have evolved a unique sensitivity to teaching and learning through ostensive cues, enhancing our capacity for cultural transmission and cooperation. However, adversities such as trauma or neglect can disrupt this developmental trajectory, leading to epistemic disruption, where individuals struggle to engage with or learn from social experiences effectively. This disruption can manifest in psychological disorders, where mentalizing failures are associated with difficulties in social functioning and in maintaining relationships. The article proposes that psychotherapeutic approaches can effectively address these disruptions, and it outlines three key aspects of communication that unfold in psychotherapeutic interventions. It discusses how the effectiveness of these interventions may hinge on the reestablishment of epistemic trust, enabling patients to reengage with their social environments constructively and adaptively. [ABSTRACT FROM AUTHOR]

This introduction to the special issue on mentalization-based treatment (MBT) with children, adolescents, and families highlights a range of conceptual and clinical contributions that illustrate the richness and usefulness of applying developmental and family systems perspectives to an MBT framework to alleviate the plight of young people and their parents. [ABSTRACT FROM AUTHOR]

Background: Attachment styles and mentalizing are among the psychological factors that are related to emotion regulation skills, the use of mentalizing ability is related to the ability of the ego in people. Therefore, investigating the path of mentalizing evolution through attachment styles to ego empowerment is a basic necessity. Aims: The purpose of this study was to predict mentalizing based on attachment styles with the mediating role of ego empowerment in students. Methods: The research method is descriptive-correlational, which was done using structural equation modeling. The study population includes all students of the Faculty of Humanities of the Islamic Azad University of Qom Branch in 2023-2024. The sample consisted of 335 students of Islamic Azad University, Qom Branch, who were selected by convenience sampling method and answered the Reflective Performance Questionnaire (Fonagy et al., 2016), Adult Attachment Styles Questionnaire (Collins & Reed, 1990), and Ego Empowerment Scale (Markstrom et al., 1997). To analyze the data, structural equation modeling was used using SPSS version 19 and Amos software version 24. Results: The results of structural equation modeling showed that secure attachment style, avoidant attachment, ambivalent attachment, and ego empowerment had a direct and significant causal effect on confidence and uncertainty (P< 0.05). Also, ambivalent attachment style, secure attachment style, and avoidant attachment style had a direct and significant causal effect on ego empowerment (P< 0.05). The results also showed that 60% of the variance of ego empowerment is explained by attachment styles, 23% of the variance of confidence, and 46% of the variance of uncertainty is explained by attachment styles and ego empowerment. Conclusion: Based on the findings of the research, it can be concluded that secure attachment style, avoidant attachment, ambivalent attachment, and ego empowerment as factors affecting mentalizing can lead us to a deeper understanding of mentalizing, and by teaching students the formation of different attachment styles and ego structure, mentalizing can be strengthened in them. [ABSTRACT FROM AUTHOR]

Abstract Background Deficits in mentalizing and attachment occur in the autism and schizophrenia spectrum, and their extended traits in the general population. Parental attachment and the broader social environment highly influence the development of mentalizing. Given the similarities in the symptomatology and neurodevelopmental correlates of autism spectrum disorder (ASD) and schizophrenia (SCH), it is crucial to identify their overlaps and differences to support screening, differential diagnosis, and intervention. Methods This cross-sectional study utilized questionnaire data from 2203 adults (65.1% female, mean age[SD] = 37.98[9.66]), including participants diagnosed with ASD, SCH, and those exhibiting subclinical traits to investigate the associations between mentalizing, attachment, and perceived social support during adolescence across the autistic and schizotypy spectrum. Results It was revealed that both autistic and schizotypal traits have comparable effects on insecure adult attachment, primarily through challenges in mentalizing. The impact of mentalizing deficits on adult attachment slightly varies between autistic and schizotypal traits. Conversely, perceived social support during adolescence relates to improved mentalizing and secure adult attachment as a protective factor during development. Conclusions These outcomes highlight the significance of supportive therapeutic relationships and community care while suggesting directions for further research and collaborative treatments addressing ASD and SCH, considering the differential impact of mentalizing on adult attachment.

Wen Chen,1,2 Yun Li,2 Haitham Jahrami,3,4 Weiyan Wang,5 Wei Zheng,2 Yuxia Huang,1 Nicola Luigi Bragazzi,6,7 Weijia Gao1 1Department of Child Psychology, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children’s Regional Medical Center, Hangzhou, People’s Republic of China; 2Department of Psychiatry, Xiamen Xianyue Hospital, Xiamen, People’s Republic of China; 3College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain; 4Ministry of Health, Manama, Bahrain; 5Affiliated Mental Health Center & Hangzhou Seventh People’s Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 6Laboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, Toronto, Canada; 7Human Nutrition Unit (HNU), Department of Food and Drugs, Medical School, University of Parma, Parma, ItalyCorrespondence: Weijia Gao, Department of Child Psychology, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children’s Regional Medical Center, Hangzhou, Zhejiang Province, People’s Republic of China, Email 6314017@zju.edu.cn Nicola Luigi Bragazzi Human Nutrition Unit (HNU), Department of Food and Drugs, Medical School, University of Parma, Parma, Italy, Email robertobragazzi@gmail.comPurpose: This study focused on the validation of the Three-Factor Reflective Functioning Questionnaire for Youth(RFQY) within a sample of Chinese adolescents.Patients and Methods: All the items of the RFQY were translated into Chinese language through the process of translation and back translation. A total of 532 adolescents aged between 12– 20 years completed the Chinese version of RFQY, McLean Screening Instrument for Borderline Personality Disorder (MSI-BPD), Basic Empathy Scale (BES), and the 20-item Toronto Alexithymia Scale (TAS-20).Results: Twenty items meeting psychometric standards were retained in the Chinese version of the RFQY. The indices for confirmatory factor analysis, including χ 2/df (2.354), SRMR (0.053), GFI (0.930), CFI (0.921), TLI (0.910), and RMSEA (0.050), all conformed to the requirements of psychometrics. The Cronbach’s alpha coefficients for the three factors, “uncertainty/confusion”, “interest/curiosity”, and “excessive certainty”, were 0.820, 0.673, and 0.839, respectively, with test-retest reliability scores of 0.751, 0.643, and 0.764. A significant positive correlation was found between uncertainty/confusion and symptoms of borderline personality disorder (BPD), particularly in adolescents with high BPD traits. Excessive certainty was positively correlated with unstable interpersonal relationships, while the interest/curiosity factor shows no significant correlation with BPD symptoms. The uncertainty/confusion factor demonstrates a complex relationship with empathy, correlating positively with affective empathy but negatively with cognitive empathy. The uncertainty/confusion factor shows a significant positive correlation with alexithymia, while the factor of excessive certainty demonstrates the opposite effect. Additionally, a significant negative correlation exists between the interest/curiosity factor and the externally oriented thinking.Conclusion: This study validates the Chinese version of the Reflective Functioning Questionnaire for Youth (RFQY), demonstrating its reliability and validity in assessing reflective functioning among Chinese adolescents. This enhances the understanding of reflective functioning and its role in adolescent mental health.Keywords: mentalizing, adolescence, psychometric validation, borderline personality disorder

Background: Despite the increasing proportion of older-aged individuals suffering from problematic gambling, research on gambling among this specific age cohort is still in its infancy. Chasing is a pathognomonic feature of disordered gambling and is considered one of the key risk factors in the transition from recreational to disordered gambling. Despite the increased research on chasing over the past decade, no previous study has ever examined the psychological determinants of chasing behavior among old-aged gamblers. Given the importance of chasing in facilitating and maintaining problem gambling, and the paucity of research examining gambling among older individuals, the present study is the first to empirically investigate the joint role of chasing behavior, negative affectivity, and mentalizing among older-aged gamblers. Methods: The sample comprised 116 older-aged gamblers who were administered the South Oaks Gambling Screen (SOGS), the Depression Anxiety Stress Scale (DASS-21) and the Reflective Functioning Questionnaire (RFQ-8) to assess gambling severity, psychological distress, and mentalizing, respectively. Participants also performed the ChasIT, a computerized task that assesses chasing behavior, in which participants were randomly assigned to three different experimental conditions: loss, control, and win. Results: No effect of the experimental conditions of ChasIT on chasing behavior was observed. Regression analyses indicated that heightened levels of gambling severity and lower levels of certainty about mental states (i.e., hypermentalizing) predicted both the decision to chase and chasing frequency. Along with problem gambling and hypermentalizing, chasing frequency was also predicted by high levels of depression. Conclusions: The present study demonstrated the association between disordered gambling, depression, and hypermentalizing in chasing behavior among older-aged gamblers. The findings make an important contribution to providing insight regarding variables that are associated with chasing among older-aged gamblers, one of the least represented populations of gamblers in the literature. The results suggest that specific training on mentalizing abilities could help gamblers to reflect on their own behaviors in terms of mental states, rather than following the impulse to gamble in order to ameliorate poor mood. [ABSTRACT FROM AUTHOR]

Although mentalizing abilities in autistic adults without intelligence deficits are similar to those of control participants in tasks relying on verbal information, they are dissimilar in tasks relying on non-verbal information. The current study aims to investigate mentalizing behavior in autism in a paradigm involving two important nonverbal means to communicate mental states: eye gaze and speech intonation. In an eye-tracking experiment, participants with ASD and a control group watched videos showing a virtual character gazing at objects while an utterance was presented auditorily. We varied the virtual character's gaze duration toward the object (600 or 1800 ms) and the height of the pitch peak on the accented syllable of the word denoting the object. Pitch height on the accented syllable was varied by 45 Hz, leading to high or low prosodic emphasis. Participants were asked to rate the importance of the given object for the virtual character. At the end of the experiment, we assessed how well participants recognized the objects they were presented with in a recognition task. Both longer gaze duration and higher pitch height increased the importance ratings of the object for the virtual character overall. Compared to the control group, ratings of the autistic group were lower for short gaze, but higher when gaze was long but pitch was low. Regardless of an ASD diagnosis, participants clustered into three behaviorally different subgroups, representing individuals whose ratings were influenced (1) predominantly by gaze duration, (2) predominantly by pitch height, or (3) by neither, accordingly labelled "Lookers," "Listeners" and "Neithers" in our study. "Lookers" spent more time fixating the virtual character's eye region than "Listeners," while both "Listeners" and "Neithers" spent more time fixating the object than "Lookers." Object recognition was independent of the virtual character's gaze duration towards the object and pitch height. It was also independent of an ASD diagnosis. Our results show that gaze duration and intonation are effectively used by autistic persons for inferring the importance of an object for a virtual character. Notably, compared to the control group, autistic participants were influenced more strongly by gaze duration than by pitch height. [ABSTRACT FROM AUTHOR]

ABSTRACT Out‐of‐home childcare is increasingly essential in many children's lives, significantly impacting their wellbeing and development. Central to high‐quality care is the concept of caregiver mind‐mindedness (MM), the ability to recognize a child as a unique psychological individual with thoughts, feelings, intentions etc., as this capacity is linked with more optimal responsiveness to children's needs. Despite its importance, the factors influencing MM in professional caregivers remain under‐researched. We examined the association between structural factors, self‐reported adult attachment, and caregiver representational MM assessed in an interview. The sample consisted of 128 childcare professionals from 30 Danish early childcare centers (children aged 0–2.9 years), participating in a randomized controlled trial. Overall, our results showed that longer employment in the current position was associated with higher levels of representational MM, i.e., increased tendency to describe children in terms of their mental states as opposed to more behavioral or external features. In contrast, more years of experience working in childcare as well as attachment‐related avoidance were associated with lower levels of representational MM. These results indicate that personal characteristics, like adult attachment, may be a relevant focus for early education and care research and training. [ABSTRACT FROM AUTHOR]

Given the relevance of caregivers' perceptions, cognitions, and emotions about their child's mental states for caregiving behavior and children's development, researchers from multiple theoretical perspectives have developed constructs to assess caregivers' cognitions, resulting in a large but scattered body of literature. In this article, we highlight the conceptual overlap among and uniqueness of six constructs assessing caregivers' cognitions about their child at 36 months and younger: infant intentionality, mental representations, mind‐mindedness, parental embodied mentalizing, parental empathy, and parental reflective functioning. We define constructs, present approaches to measurement, and propose elements of importance that fall under the umbrella of caregivers' cognitions and that may be associated differentially with children's early cognitive and social–emotional development. We conclude with recommendations for researchers aiming to capture caregivers' cognitions about their child's mental states, whether focusing on one of the six reviewed constructs or on specific elements (e.g., awareness of the child's mind or accuracy of caregivers' perceptions of their child) under the umbrella of caregivers' cognitions. [ABSTRACT FROM AUTHOR]

Individuals with autism spectrum disorder (ASD) show impaired mentalizing skills, specifically in understanding intentions. They have difficulty understanding social situations with multiple cues due to their limited ability to perceive subtle social contextual cues. Studies that used comic strips and the strange stories as intention attribution tests found that individuals with ASD exhibit a reduced ability in attributing intentions compared to inferring causal consequences. This study aims to use static photographs of social scenes taken in everyday settings to investigate the ability of adolescents with ASD to infer intentions in social contexts, and to explore how intention inference relates to working memory and basic attention, including sustained attention, selective attention, and divided attention. The results show that the physical causal inference ability of adolescents with ASD is comparable to typically developing adolescents, whereas intention inference is notably weaker. Furthermore, working memory predicts physical causal inference and divided attention predicts intention inference in ASD. [ABSTRACT FROM AUTHOR]

Objectives: Treatments for borderline personality disorder (BPD) and post‐traumatic stress disorder (PTSD) are less effective for patients with co‐occurring symptoms of both disorders, who are considered to have complex PTSD (cPTSD), compared with patients with either condition alone. Evidence suggests that co‐occurrence of symptoms indicates greater impairment in mentalizing. This study examines evidence for targeting mentalizing when treating individuals with co‐occurring symptoms, irrespective of their exposure to developmental trauma and, for the first time, investigates the mediational role of mentalizing in the associations between BPD symptomatology and cPTSD. Design: We identified in a routine clinical service a group of patients with BPD, with or without co‐occurring symptoms of PTSD. We hypothesized that patients with co‐occurring symptoms and a history of childhood maltreatment will show more severe clinical profiles and greater mentalizing problems, which in turn lead to symptoms consistent with cPTSD. Method: Clinical profiles of 72 patients with BPD (43 with and 29 without co‐occurring symptoms of PTSD; mean age in both groups 28 years, 79% and 83% female, respectively) were identified using the Structured Clinical Interview for DSM‐IV Axis II Disorders. Patients completed self‐report measures of BPD and PTSD symptoms, well‐being, dissociation and reflective functioning. Childhood trauma histories were evaluated. Results: Compared with patients with BPD‐only, those with co‐occurring BPD and PTSD showed greater severity in terms of BPD and dissociative symptoms, met a broader range of BPD diagnostic criteria, had a greater sense of personal worthlessness and self‐evaluated their well‐being as considerably diminished. This group was also more inclined to recall increased instances of childhood sexual abuse. In a mediation analysis, mentalizing acted as a partial mediator for the relationship between BPD severity and cPTSD, as well as between dissociative symptoms and cPTSD. Interestingly, mentalizing did not mediate the relationship between childhood sexual abuse and cPTSD. Conclusions: Overall, the correlational findings are consistent with an intended focus on mentalizing to treat cPTSD symptoms in individuals who also meet criteria for a diagnosis of BPD. [ABSTRACT FROM AUTHOR]

Background: P-factor and mentalizing theory and research set perspectives for transdiagnostic psychiatric treatments. Aims: To test the effects of a low-cost mentalization-based health education program (the Thoughtful program) in an unselected waiting list population, from a psychiatric outpatient clinic in North Norway. Methods: Waiting list patients were randomized (1:1 allocation): 79 patients in the control group were offered standard individual assessment and treatment. Seventy-nine patients in the intervention group were offered a one-day (six-hour) group-based Thoughtful course, plus individual assessment, and treatment. Results: During a 6-month follow-up period, the number of patients in active assessment and treatment was 66% higher in the control group than in the intervention group. Self-reported patient questionnaire scores on mentalizing, well-being and suicidal ideation scores showed no significant changes in the control group. In the intervention group, significant changes were reported: Mentalizing scores improved by 72% and well-being scores improved by 55%. Suicidal ideation scores were not significantly changed. No adverse effects were registered. Limitations: The results from this study should be interpreted with caution because of a small population size and low questionnaire response rate. The follow up period was limited to 6 months. Transfer of program information from intervention group patients to control group patients could not be guaranteed. It may be considered a limitation that diagnostic pattern analysis was not included in the study. Conclusions: A low-cost transdiagnostic mentalization-based educational program in an outpatient psychiatry clinic may improve patient mentalizing and wellbeing without adverse effects and reduce the use of hospital services. [ABSTRACT FROM AUTHOR]

Social neuroscience has often been criticized for approaching the investigation of the neural processes that enable social interaction and cognition from a passive, detached, third-person perspective, without involving any real-time social interaction. With the emergence of second-person neuroscience, investigators have uncovered the unique complexity of neural-activation patterns in actual, real-time interaction. Social cognition that occurs during social interaction is fundamentally different from that unfolding during social observation. However, it remains unclear how the neural correlates of social interaction are to be interpreted. Here, we leverage the active-inference framework to shed light on the mechanisms at play during social interaction in second-person neuroscience studies. Specifically, we show how counterfactually rich mutual predictions, real-time bodily adaptation, and policy selection explain activation in components of the default mode, salience, and frontoparietal networks of the brain, as well as in the basal ganglia. We further argue that these processes constitute the crucial neural processes that underwrite bona fide social interaction. By placing the experimental approach of second-person neuroscience on the theoretical foundation of the active-inference framework, we inform the field of social neuroscience about the mechanisms of real-life interactions. We thereby contribute to the theoretical foundations of empirical second-person neuroscience. [ABSTRACT FROM AUTHOR]

Mental disorders are associated with difficulties to correctly infer the mental states of other's (theory of mind; ToM). These inferences either relate to affective states of others (affective ToM) or to their thoughts, intentions, or beliefs (cognitive ToM) and can be associated with mental disorder. The current study explores the influence of individual and situational effects on the measurement of ToM abilities within two clinical samples, to increase generalizability. We analyzed data from 229 in-patients; 103 patients treated for alcohol use disorder and 126 patients treated for a personality disorder. ToM was assessed with the Movie for the Assessment of Social Cognition (MASC). We analyzed changes in test performance over the course of the test using a logistic linear mixed effects model. Performance on the cognitive ToM items decreased over time, while performance on the affective ToM items increased over time. This difference was more pronounced among older individuals. The results show important moderators of ToM performance that might help to resolve inconsistencies in the current literature about ToM abilities in different clinical or age groups. [ABSTRACT FROM AUTHOR]

Background: Deficits in mentalizing and attachment occur in the autism and schizophrenia spectrum, and their extended traits in the general population. Parental attachment and the broader social environment highly influence the development of mentalizing. Given the similarities in the symptomatology and neurodevelopmental correlates of autism spectrum disorder (ASD) and schizophrenia (SCH), it is crucial to identify their overlaps and differences to support screening, differential diagnosis, and intervention. Methods: This cross-sectional study utilized questionnaire data from 2203 adults (65.1% female, mean age[SD] = 37.98[9.66]), including participants diagnosed with ASD, SCH, and those exhibiting subclinical traits to investigate the associations between mentalizing, attachment, and perceived social support during adolescence across the autistic and schizotypy spectrum. Results: It was revealed that both autistic and schizotypal traits have comparable effects on insecure adult attachment, primarily through challenges in mentalizing. The impact of mentalizing deficits on adult attachment slightly varies between autistic and schizotypal traits. Conversely, perceived social support during adolescence relates to improved mentalizing and secure adult attachment as a protective factor during development. Conclusions: These outcomes highlight the significance of supportive therapeutic relationships and community care while suggesting directions for further research and collaborative treatments addressing ASD and SCH, considering the differential impact of mentalizing on adult attachment. [ABSTRACT FROM AUTHOR]

Objectives: This study explored participant experience of mentalization after the completion of an introductory MBT group within an Irish prison. Methods: Data were collected from four participants using semi-structured interviews which were analyzed according to IPA methodology. Results: Four group experiential themes were identified from the data: making sense of difficulties with emotions in the context of early life experiences, learning to feel and manage emotions, keeping other minds in mind and mentalizing in practice. Conclusions: This study adds to the wider qualitative literature on MBT and presents a unique insight into participant experiences of developing their mentalizing capacity within a prison setting. [ABSTRACT FROM AUTHOR]

An important correlate of mental health problems is mentalizing capacity, which appears to be particularly influential during adolescence. However, quality of life has not been studied in relation to mentalizing capacity among adolescents. This study aimed to translate the Reflective Function Questionnaire for Youth (RFQY) into Hungarian, present its psychometric properties, and assess its relationship with demographic characteristics, psychopathology and quality of life. A community sample of 384 youths aged 12–18 years completed the RFQY, the Measure of Quality of Life for Children and Adolescents, and the Strengths and Difficulties Questionnaire. First, we conducted an exploratory factor analysis with direct oblimin rotation on the RFQY items. Next, we assessed the associations between the RFQY and demographics, quality of life, and psychopathology. The EFA resulted in four factors: Internal-self, Internal-other, Self-other, and Strong emotions. The Cronbach's alpha coefficients of the scales were.81,.82,.67, and.80, respectively. The subscales were uniquely associated with psychopathology and quality of life. Our study provides the first psychometric support for the Hungarian version of the RFQY and indicates that adolescents suffering from internalizing, externalizing symptoms or lower levels of quality of life could benefit from interventions aimed at enhancing mentalizing capacity. Plain language summary: An important correlate of mental health problems is mentalizing capacity, which appears to be particularly influential during adolescence. However, quality of life has not been studied in relation to mentalizing capacity among adolescents. This study aimed to translate the Reflective Function Questionnaire for Youth (RFQY) into Hungarian, present its psychometric properties, and assess its relationship with demographic characteristics, psychopathology and quality of life. A community sample of 384 youths between the ages of 12 and 18 completed the RFQY, the Measure of Quality of Life for Children and Adolescents, and the Strengths and Difficulties Questionnaire. Our study provides the first psychometric support for the Hungarian version of the RFQY and indicates that adolescents suffering from internalizing, externalizing symptoms or lower levels of quality of life could benefit from interventions aimed at enhancing mentalizing capacity. [ABSTRACT FROM AUTHOR]

Background: Suicide attempt (SA) lethality is associated with heightened suicidal desires and social cognition deficits. Fearlessness about death (FAD) and hypomentalizing may play a role in SA and self-harm. Although studies have identified relationships between these constructs, this line of research is still limited. We aimed to explore the mediating role of FAD and mentalizing between suicidal ideation and both SA lethality and self-harm. Method: 1,371 suicide attempters (70.1% women; M = 40 years) from seven Spanish hospitals participated. We used the Fearlessness About Death (ACSS-FAD) subscale, the Reflective Functioning Questionnaire-8 (RFQ-8), and the Columbia Suicide Severity Rating Scale (CSSRS). We conducted serial multiple mediation analyses with suicidal ideation as exposure; FAD and mentalizing as mediators; SA lethality and self-harm as outcomes. Results: Indirect effects were found of suicidal ideation on self-harm (B = 0.08, CI = 0.03-0.15) and SA lethality mediated by FAD (B = 0.02, CI = 0.001-0.04); indirect effects of suicidal ideation on self-harm through mentalizing (B = 0.10, CI = 0.04-0.167), and total indirect effects between suicidal ideation and self-harm through FAD and mentalizing (B = 0.18, CI = 0.11-0.27). Conclusions: Interventions addressing mentalizing and FAD may help reduce SA lethality and self-harm risk. [ABSTRACT FROM AUTHOR]

Trauma-Focused mentalization-based treatment (MBT-TF) is an adaptation of mentalization-based treatment (MBT) specifically developed for patients suffering from attachment or complex trauma, with the possibility of co- occurring borderline personality pathology. The creation of MBT-TF was driven by previous research and observations that interventions centered on mentalizing could be significantly improved by directly addressing the impact of trauma. MBT-TF aims to mitigate symptoms that arise post-trauma, such as hyperarousal, hypervigilance, intrusions, flashbacks, avoidance behaviors, dissociative experiences, negative perceptions of self and others, and ensuing relational difficulties. Implemented as a group intervention, MBT-TF typically spans 6-12 months. From a mentalizing perspective, trauma, particularly attachment trauma, leads to a failure in processing the effects of trauma through and with others. Stress and attachment behavioral systems are disrupted, which undermines the capacity for epistemic trust, and impairs mentalizing abilities. This paper offers a concise summary of the reasoning for MBT-TF's creation, its theoretical underpinnings, and its clinical strategy for addressing the adverse impacts of trauma. It further details the treatment phases, their main goals, and their interventions, supplemented by clinical case examples that underscore MBT-TF's distinctive attributes and frequent clinical hurdles. [ABSTRACT FROM AUTHOR]

Mentalization‐based treatment (MBT) is a spectrum of interventions that share a central focus on improving the capacity for mentalizing. Although MBT was originally developed as a treatment for individuals with borderline personality disorder, its scope and focus have been broadened to become a socioecological approach that stresses the role of broader sociocultural factors in determining the closely related capacities for mentalizing and epistemic trust. This special issue brings together some of the newest developments in MBT that illustrate this shift. These contributions also highlight several current limitations in mentalization‐based approaches, providing important pointers for further research. In this editorial, we first outline the broadening scope of the mentalizing approach, and then provide a discussion of each of the contributions to this special issue in the context of the need for further research concerning some of the key assumptions of mentalization‐based approaches and their implementation in clinical practice. We close this editorial with considerations concerning future research. [ABSTRACT FROM AUTHOR]

Trait anger reflects a tendency to feel irritation, annoyance, and rage, and involves a narrowing of cognition and attention. This narrowed scope may impact the capacity to understand the mental states of oneself and others (mentalizing), which for fathers of infants may compromise bonding and caregiving involvement. Here, we investigated the extent to which mentalizing mediated the relationship between father trait anger and both father–infant bonding and father involvement in infant caregiving. Data were from 168 fathers (M = 30.04 years of age, SD = 1.36) of 190 infants (M = 7.58 months of age, SD = 5.06) in the longitudinal Men and Parenting Pathways (MAPP) study. We assessed fathers' preconception trait anger at Wave 1 and their mentalizing 2 years later at Wave 3. At Waves 3, 4, and/or 5, we assessed father–infant bonding and father involvement in infant caregiving when men had an infant younger than 18 months of age. Associations were examined using path analysis. Poorer mentalizing fully mediated the relationship between preconception trait anger and father–infant bonding (total score), but not involvement in infant caregiving. Further, poorer mentalizing fully mediated the relationships between trait anger and each component of the father–infant bond (i.e., patience and tolerance, affection and pride, and pleasure in interactions). Findings suggest that for men high on trait anger, targeted interventions that facilitate mentalizing capacities may help to develop a foundation for a strong father–infant bond. Interventions may be offered on becoming a father (perinatal), or prior to becoming a father (preconception) to prevent future bonding problems. [ABSTRACT FROM AUTHOR]

Many social cognitive assessments that were developed specifically for use in clinical populations are now being widely used in undergraduate populations, either to provide a comparison for clinical groups or to explore performance across the continuum from healthy to subclinical populations. However, the appropriateness of using these assessments in the general population is unclear. The current study, therefore, seeks to determine whether the Social Cognition Psychometric Evaluation (SCOPE) battery retains its psychometric properties when used in an undergraduate sample. The initial SCOPE battery was administered to 265 undergraduate participants, and the utility of the tasks was measured by assessing floor and ceiling effects. Internal consistency, discriminant and convergent validity are reported for each task, and the relationship between task performance and neurocognition and social functioning were assessed. Several of the tasks demonstrated limited utility, with the Hinting Task specifically demonstrating a pronounced ceiling effect. Only two measures of social cognitive biases achieved satisfactory internal consistency. Select tasks demonstrated small, but significant relationships with social functioning outcomes and significantly predicted 2–3% of variance above neurocognition alone. Despite the association with social functioning, results indicate that the psychometric properties demonstrated in the initial SCOPE study with a clinical sample do not fully extend to a healthy undergraduate population and highlight the need for social cognitive tasks that validly assess ability across the continuum. [ABSTRACT FROM AUTHOR]

Toxicity in online social interactions is a growing and significant concern. The current focus has been on the broader effects of toxicity, such as polarization, misinformation, and moral outrage. However, to advance our understanding of online toxicity, we also need to consider the role of the online and disembodied nature of interactions in giving rise to such toxicity. The Disembodiment, Anonymity, and lack of Disinhibition (DAD) framework conceptualizes three core roots of impaired social interactions and how they persist in a vicious cycle. An improved understanding of how impaired interactions unfold in the online world can help design interventions that focus on skills and technology for better communication. Online communication is central to modern social life, yet it is often linked to toxic manifestations and reduced well-being. How and why online communication enables these toxic social effects remains unanswered. In this opinion, we propose three roots of online toxicity: disembodiment, limited accountability, and disinhibition. We suggest that virtual disembodiment results in a chain of psychological states primed for deleterious social interaction. Drawing from differences between face-to-face and online interactions, the framework highlights and addresses the fundamental problems that result in impaired communication between individuals and explicates its effects on social toxicity online. [ABSTRACT FROM AUTHOR]

Mentalizing difficulties are an established correlate of eating disorders, but there is a need to establish the validity and reliability of easy-to-administer instruments to measure the construct in adolescents. This study evaluated the psychometric properties of a five-item version of the Reflective Function Questionnaire for Youth (RFQY-5) in a sample of adolescents with restrictive eating disorders recruited for a prospective observational study. Adolescents completed the 46-item version of the RFQ-Y at the start of treatment (T1) (n = 171) and nine months later (n = 51). The factor structure, internal reliability and convergent validity of the RFQY-5 were assessed at T1. Sensitivity to change was assessed in a subsample of n = 51 who completed the RFQ-Y nine months after the start of treatment (T2). At T1, the RFQY-5 demonstrated inadequate internal reliability (McDonald's Omega = 0.657) and poor model fit for the unidimensional structure (Χ2(5) = 29.98; p < 0.001; CFI = 0.801; TLI = 0.602; RMSEA = 0.171; SRMR = 0.070). Convergent validity was partially supported. The RFQY-5 was not sensitive to change. The RFQY-5 was found to have inadequate psychometric properties in adolescents with restrictive eating disorders. Psychometric studies are needed to further develop valid and reliable measures of mentalizing for this population. [ABSTRACT FROM AUTHOR]

Objectives: Mentalizing difficulties are central to borderline personality disorder (BPD), have severe consequences, and are an explicit focus in mentalizationbased treatment. The significance of mentalizing capacity as a predictor or mediator of change is however still uncertain due to a scarcity of research. The Mentalization Breakdown Interview (MBI) was developed as a time saving tool for studying psychotherapy processes and outcome in borderline pathology. This study aimed to investigate the convergent validity of reflective functioning (RF) ratings based on the MBI (MBI-RF) by a comparison with the gold standard, i.e., RF assessments based on the Adult Attachment Interview (AAI-RF). A secondary aim was to investigate how MBI-RF relates to core symptoms of BPD, levels of functional impairment and symptom distress compared with AAI-RF. Method: Forty-five patients with BPD or significant BPD traits were included. MBI-RF and AAI-RF were rated using the Reflective Functioning Scale. Levels of MBI-RF and AAI-RF and the correlation between the measures were calculated, as well as their associations with the Difficulties in Emotion Regulation Scale, Levels of Personality Functioning-Brief Form 2.0, Work and Social Adjustment Scale, Patient Health Questionnaire, Depression, Generalized Anxiety Disorder-7, self-harm, suicide attempts, and PD diagnostics. Results: The correlation between MBI-RF and AAI-RF was 0.79 (p<0.01), indicating high convergent validity. There were few significant associations between MBI-RF and AAI-RF and clinical measures. Conclusions: The study provides support for the convergent validity of the MBI as a BPD-focused RF assessment method. The MBI has the potential as a time saving, reliable and valid method to be applied in treatment research on patients with borderline pathology. The results indicate that measures of MBI-RF and AAIRF are different from clinical symptoms. [ABSTRACT FROM AUTHOR]

Securing an accurate autism‐spectrum‐condition diagnosis, particularly among women, remains challenging for autistic adults. Building upon previous research highlighting the short‐story task (SST) as a promising tool for detecting fiction‐based mentalizing difficulties in autistic adults, this study expands its scope. We investigated the SST's discriminative capacity across three distinct groups: autistic individuals (n = 32), nonautistic individuals without mental health problems (n = 32), and nonautistic individuals with clinical depression (n = 30). All three groups differed significantly from each other in their SST mentalizing score with the nonautistic group having the highest scores, the nonautistic but depressed group having medium scores and the autistic group showing the lowest scores. Receiver operator curve (ROC) analysis reaffirmed the SST's efficacy as a discriminator. Moreover, a linear regression analysis identified the SST mentalizing score, the SST comprehension score, and the number of books read per month as significant predictors of autism‐spectrum‐condition diagnosis. These findings bolster the SST's potential as a valuable adjunct in autism diagnostics, highlighting its discriminatory ability across diverse samples. Lay Summary: Finding out if someone is autistic, especially if they are a woman, can be really difficult. A new test called the short‐story task seems to be a new promising diagnostic tool. The short‐story task looks at how well people understand the thoughts and feelings of nonautistic people within a story, and it seems to be good at telling the difference between autistic and nonautistic people. In our study, we looked at three groups of people: those who are autistic, those who are not autistic and without mental health problems, and those who are not autistic but suffer from depression. We found that the short‐story task was good at figuring out who was autistic, who was not and who had depression. We also found that how well someone did on the test, and how many books they read each month were all linked to whether they were autistic. This means that the short‐story task could be a useful tool for autism diagnostics. [ABSTRACT FROM AUTHOR]

Prior studies in Social Neuroeconomics have consistently reported activation in social cognition regions during interactive economic games, suggesting mentalizing during economic choice. Such mentalizing occurs during active participation in the game, as well as during passive observation of others' interactions. We designed a novel version of the classic false-belief task (FBT) in which participants read vignettes about interactions between agents in the ultimatum and trust games and were subsequently asked to infer the agents' beliefs. We compared activation patterns during the economic games FBT to those during the classic FBT using conjunction analyses. We find significant overlap in the left temporoparietal junction (TPJ) and dorsal medial prefrontal cortex, as well as the temporal pole (TP) during two task phases: belief formation and belief inference. Moreover, generalized Psychophysiological Interaction (gPPI) analyses show that during belief formation, the right TPJ is a target of both the left TPJ and the right TP seed regions, whereas during belief inferences all seed regions show interconnectivity with each other. These results indicate that across different task types and phases, mentalizing is associated with activation and connectivity across central nodes of the social cognition network. Importantly, this is the case for both the novel economic games and the classic FBTs.

Abstract Background Mentalizing refers to the ability to understand one’s own and others’ mental states. Mentalizing is considered a key component of social cognition and healthy personality development. A multinational assessment tools able to appraise the multidimensional and multifaceted aspects of this complex construct are needed. Objective The present study had two aims: (a) validate an English version of the Multidimensional Mentalizing Questionnaire (MMQ, 33 items) which was designed to assess mentalizing based on an integrated and multilevel model of mentalizing; (b) explore the correlational relationships between the six dimensions of the MMQ and a set of sociodemographic, psycho-cognitive, mental health, and socio-functional variables. Methods Overall, 1823 individuals (age: 19–76 years old [M = 45; SD = 16]; sex: male = 48.51%, female = 50.57%, non-binary = 0.9%) participated in an online survey. While the participants came from 77 different countries, most of them were residents in UK and USA (95%). Data analytics include confirmatory factorial analysis and Pearson correlations. Results The CFA results validated the factorial structure of a 28-items MMQ-English version, with acceptable goodness of fit indices. Regarding the psychometric properties, the MMQ-English version showed good internal reliability and significant positive correlation with another scale designed to assess an analogue construct showing a fair convergent validity. The findings indicated that males, individuals with lower levels of education, lower socio-economic status, depressed, and with a higher score of loneliness are significantly more likely to report poor mentalizing compared with females, individuals with higher education level, greater SES, happier, and with lower scores of loneliness. Conclusion The present study validated the English version of the MMQ.

BackgroundAlthough potential links between oxytocin (OT), vasopressin (AVP), and social cognition are well-grounded theoretically, most studies have included all male samples, and few have demonstrated consistent effects of either neuropeptide on mentalizing (i.e. understanding the mental states of others). To understand the potential of either neuropeptide as a pharmacological treatment for individuals with impairments in social cognition, it is important to demonstrate the beneficial effects of OT and AVP on mentalizing in healthy individuals.MethodsIn the present randomized, double-blind, placebo-controlled study (n = 186) of healthy individuals, we examined the effects of OT and AVP administration on behavioral responses and neural activity in response to a mentalizing task.ResultsRelative to placebo, neither drug showed an effect on task reaction time or accuracy, nor on whole-brain neural activation or functional connectivity observed within brain networks associated with mentalizing. Exploratory analyses included several variables previously shown to moderate OT's effects on social processes (e.g., self-reported empathy, alexithymia) but resulted in no significant interaction effects.ConclusionsResults add to a growing literature demonstrating that intranasal administration of OT and AVP may have a more limited effect on social cognition, at both the behavioral and neural level, than initially assumed. Randomized controlled trial registrations: ClinicalTrials.gov; NCT02393443; NCT02393456; NCT02394054.

Introduction: The relationship between neural social cognition patterns and performance on social cognition tasks in daily life is a topic of debate, with key consideration given to the extent to which theory of mind (ToM) brain circuits share properties reflecting everyday social functioning. To test the efficacy of ecological stimuli in eliciting brain activation within the ToM brain circuits, we adapted the Edinburgh Social Cognition test social scenarios, consisting of dynamic ecological contextually embedded social stimuli, to a fMRI paradigm. Methods: Forty-two adults (21 men, mean age ± SD = 34.19 years ±12.57) were enrolled and underwent an fMRI assessment which consisted of a ToM task using the Edinburgh Social Cognition test scenarios. We used the same stimuli to prompt implicit (movie viewing) and explicit (silent and two-choice answers) reasoning on cognitive and affective mental states. The fMRI analysis was based on the classical random effect analysis. Group inferences were complemented with supplemental analyses using overlap maps to assess inter-subject variability. Results: We found that explicit mentalizing reasoning yielded wide neural activations when two-choice answers were used. We also observed that the nature of ToM reasoning, that is, affective or cognitive, played a significant role in activating different neural circuits. Discussion: The ESCoT stimuli were particularly effective in evoking ToM core neural underpinnings and elicited executive frontal loops. Future work may employ the task in a clinical setting to investigate ToM network reorganization and plasticity. [ABSTRACT FROM AUTHOR]

Introduction: The Theory of Mind (ToM) assessment is becoming essential to evaluate the response to a social cognition intervention and to monitor the progression of social abilities impairment in atypical conditions. In the Italian setting, the Yoni task has been recently validated in its short version (the Yoni-48 task) to evaluate ToM in the clinical setting. The present study aimed to verify the test-retest reliability and the Minimal Detectable Change (MDC) of the Yoni-48 task. Methods: The Yoni-48 task was administered to 229 healthy adults at two evaluation sessions 3 weeks apart (mean days between sessions = 20.35 ± 1.75) by a psychologist. The test-retest reliability of the Yoni-48 task accuracy and response time was tested by the Intraclass Correlation Coefficient (ICC2,1, twoway random model, absolute agreement type). Then, the MDC95 and MDC90 were computed based on the standard error of measurement. Finally, the 95% limits of agreement were plotted (LOA plot) to visualize the difference and mean score of each pair of measurements. Results: The total Yoni-48 task accuracy, but not the response time score, showed a high ICC (>0.80), with an MDC of 0.10. By plotting the LOA plot for the accuracy score no systematic trends were observed. Discussion: This evidence will support the adoption of the Yoni task in longitudinal designs. [ABSTRACT FROM AUTHOR]

Lichtenberg's chapter on "Empathy, Motivational Systems, and a Theory of Cure" was a brilliant effort to integrate his new paradigm of multimotivational systems with Kohut's empathic approach to psychotherapy. Lichtenberg shows how the clinical dialogue with patients can be monitored by using empathic perception to track shifts in motivational systems. At any given moment, a particular motivational system may become dominant. Successfully identifying the dominant motivation through empathic perception creates in patients a feeling of being understood without judgment. This ambience of safety allows for a shift that activates an exploratory motivation with patients and a spirit of inquiry. An observational platform is created where experience from the past with attachment figures and interaction in the here and now in therapy can be explored from new perspectives. Recent research in psychotherapy that uses monitoring the clinical dialogue with patients by tracking shifts in motivational systems supports the view of its positive effects. Lichtenberg's "theory of cure" is based on the premise that an empathic perception that monitors shifts in motivational systems will mobilize intrinsic self-righting capacities in patients. I note that there is controversy about what mutative factors in psychotherapy are most important: building an ambience of safety and trust or creating new insights into personal and internal conflicts through the use of language and symbolic representations. Both factors are crucial for positive changes in psychotherapy, and their importance will vary from patient to patient and from one patient–therapist relation to another. I note that Wilma Bucci's multiple code theory that sees experience coded at subsymbolic and verbal symbolic levels supports this view. I close by proposing that we can build on Lichtenberg's multimotivational system by adding a trans-survival need to give meaning to our lives. [ABSTRACT FROM AUTHOR]

Background: Parental reflective function (PRF) is a candidate mechanism in the transmission of intergenerational trauma. This systematic review examined (1) the association between parental history of childhood maltreatment and PRF, (2) how PRF relates to attachment in children of parent survivors, and (3) whether PRF moderates the association between parental maltreatment history and child attachment. Methods: Ten databases were searched (from inception to 10 th November 2021). Inclusion criteria were primary study, quantitative, parent participants, measures of childhood maltreatment, and postnatal PRF. Exclusion criteria were qualitative, intervention follow-up, gray literature, or a review study. Risk of bias was assessed using recommended tools. Data were narratively synthesized. Results: One-thousand-and-two articles were retrieved, of which eleven met inclusion criteria (N = 974 participants). Four studies found a significant association between parental childhood maltreatment and disrupted PRF, six did not, one found mixed results. One study reported the association between childhood maltreatment and attachment (nonsignificant results). Discussion: There is no clear evidence PRF is routinely disrupted in parent survivors, though there is high heterogeneity in studies. Future research should standardize design to better understand whether PRF is a candidate mechanism in intergenerational trauma. Other: PROSPERO CRD42020223594 [ABSTRACT FROM AUTHOR]

Machado Joseph disease (MJD), also known as spinocerebellar ataxia type 3 (SCA3), is an autosomal dominant neurodegenerative disease. Mentalizing is the ability to think and understand the mental state of the other and of the self in terms of thoughts, feelings, and intentions. The aim of this study is to fill the gap in our understanding of mentalizing in MJD since there is currently very little and inconsistent research on MJD and mentalizing. A total of 18 Jews of Yemenite origin with clinically and genetically confirmed MJD, 5 pre-symptomatic MJD with a positive genetic test, and 17 Jews of Yemenite origin healthy controls, underwent a battery of tests consisting of reading the mind in the eyes (RME), Toronto Alexithymia Scale (TAS-20), and false belief test (FBt). The MJD group scored lower on the RME and FBt, and higher on TAS-20 test compared to control. A significant negative correlation was found between disease duration and RME score. All the pre-symptomatic participants scored within the normal clinical range in all tests. MJD patients demonstrated a widespread deficiency in the ability to mentalizing on a clinical level with autistic characteristics. These impairments may impact the patient's interpsychic experience and daily life interactions and have important clinical implication. Pre-symptomatic participants demonstrated normal mentalizing in all tests, suggesting that the mentalizing impairments do not precede the symptoms of ataxia and are part of the clinical picture of MJD. [ABSTRACT FROM AUTHOR]

In traditional game theory tasks, social decision‐making is centered on the prediction of the intentions (i.e., mentalizing) of strangers or manipulated responses. In contrast, real‐life scenarios often involve familiar individuals in dynamic environments. Further research is needed to explore neural correlates of social decision‐making with changes in the available information and environmental settings. This study collected fMRI hyperscanning data (N = 100, 46 same‐sex pairs were analyzed) to investigate sibling pairs engaging in an iterated Chicken Game task within a competitive context, including two decision‐making phases. In the static phase, participants chose between turning (cooperate) and continuing (defect) in a fixed time window. Participants could estimate the probability of different events based on their priors (previous outcomes and representation of other's intentions) and report their decision plan. The dynamic phase mirrored real‐world interactions in which information is continuously changing (replicated within a virtual environment). Individuals had to simultaneously update their beliefs, monitor the actions of the other, and adjust their decisions. Our findings revealed substantial choice consistency between the two phases and evidence for shared neural correlates in mentalizing‐related brain regions, including the prefrontal cortex, temporoparietal junction (TPJ), and precuneus. Specific neural correlates were associated with each phase; increased activation of areas associated with action planning and outcome evaluation were found in the static compared with the dynamic phase. Using the opposite contrast, dynamic decision‐making showed higher activation in regions related to predicting and monitoring other's actions, including the anterior cingulate cortex and insula. Cooperation (turning), compared with defection (continuing), showed increased activation in mentalizing‐related regions only in the static phase, while defection, relative to cooperation, exhibited higher activation in areas associated with conflict monitoring and risk processing in the dynamic phase. Men were less cooperative and had greater TPJ activation. Sibling competitive relationship did not predict competitive behavior but showed a tendency to predict brain activity during dynamic decision‐making. Only individual brain activation results are included here, and no interbrain analyses are reported. These neural correlates emphasize the significance of considering varying levels of information available and environmental settings when delving into the intricacies of mentalizing during social decision‐making among familiar individuals. [ABSTRACT FROM AUTHOR]

A randomized controlled parallel-group trial was conducted to investigate the effectiveness of two 10-week early childhood education and care (ECEC) interventions "SAGA" and "Pikkuli" for supporting social-emotional and verbal development. All children above the age of 4 were invited from 15 Finnish volunteer ECEC groups (n SAGA = 52, n Pikkuli = 56, n control group = 42). The children and caregivers, but not the personnel (who carried out the intervention), were blinded to the group assignment. Children in the SAGA intervention advanced in prosocial behavior and social orientation and had fewer internalizing and externalizing problems after the intervention. Children in the Pikkuli intervention advanced in prosocial behavior and had fewer internalizing problems after the intervention. There were no significant changes in any of the aforementioned outcomes in the control group. The results suggest that both interventions have good potential in supporting children's social-emotional development in the ECEC environment. [ABSTRACT FROM AUTHOR]