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为了拓展南极磷虾油的应用范围，采用喷雾干燥法制备南极磷虾油微囊粉。通过对比微囊化效果确定最佳壁材、乳化剂及工艺条件，并对最终产品各项性能指标进行测定。结果表明，制备南极磷虾油微囊粉的最佳条件为：最佳壁材组合为麦芽糊精（75%）与酪蛋白酸钠（2%），最佳乳化剂为单甘酯，单甘酯添加量2.0%，均质压力40 MPa,喷雾干燥进风温度180 ℃、出风温度90 ℃。在最佳条件下制得的南极磷虾油微囊粉表面含油率为0.68%，包埋率达到95%以上，载油量约为20%。南极磷虾油微囊粉为淡红色，具有一定的虾油味道，流动性良好，没有出现结块现象，并且复水后能够快速溶解，没有分层或漂油现象。 In order to expand the application of Antarctic krill oil, Antarctic krill oil microencapsulated powder was prepared by spray drying method. The best wall materials, emulsifier and process conditions were determined by comparing the microencapsulation effect. In addition, the performance indexes of the final product were measured. The results showed that the optimal preparation conditions of Antarctic krill oil microencapsulated powder were obtained as follows: maltodextrin (75%) and sodium caseinate (2%) used as the best wall materials combination, monoglyceride used as the best emulsifier, dosage of emulsifier 2.0%, homogenization pressure 40 MPa, inlet air temperature of spray drier 180 ℃, and outlet air temperature 90 ℃. Under the optimal conditions, the surface oil content of the Antarctic krill oil microencapsulated powder obtained was 0.68%, the embedding rate was over 95% and the oil loading capacity was about 20%. The microencapsulated powder was light red, with a certain smell of krill oil, good flowability, no agglomeration, and could be dissolved quickly after rehydration, without any delamination or oil bleaching phenomenon.