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Your search keyword '"retina blood vessel occlusion"' showing total 4 results
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4 results on '"retina blood vessel occlusion"'

1. Ultra widefield imaging of the retina [Imagen de retina de campo ultra-amplio]

Author

José Gerardo García Aguirre

Subjects
retina, genetic structures, age related macular degeneration, eye fundus, ultra widefield imaging, retina image, eye diseases, Article, retina examination, diabetic retinopathy, 7 INGENIERÍA Y TECNOLOGÍA, retina disease, uveitis, retina blood vessel occlusion, sense organs, human
Abstract

Purpose To review the evolution and usefulness of ultra widefield images of the retina. Method Literature review. Results The ability to obtain images of the ocular fundus is one of the greatest breakthroughs in our specialty. This ability has refined over time, from obtaining images with a field of 30 degrees, to obtaining images that exceed 150 degrees using equipment such as the Optos Daytona (Optos, Dunfermline, United Kingdom) or the Heidelberg Spectralis (Heidelberg Engineering, Heidelberg, Germany). These images are extremely useful to evaluate diseases such as diabetic retinopathy, retinal vascular occlusions, pediatric retinal pathology, posterior uveitis, and even diseases which classically affect the macula such as age-related macular degeneration. Conclusion Ultra widefield images of the retina have revolutionized the way we study and understand retinal pathology. As technology for obtaining these images becomes more accessible, it will surely become part of the routine evaluation of retinal diseases. © 2016 Sociedad Mexicana de Oftalmología

Published
2017

2. Ultra widefield imaging of the retina [Imagen de retina de campo ultra-amplio]

Author

García-Aguirre G., Henaine-Berra A., Fromow-Guerra J., Martínez-Castellanos M.A., Salcedo-Villanueva G., and Morales-Cantón V.

Subjects
retina, genetic structures, age related macular degeneration, eye fundus, ultra widefield imaging, retina image, eye diseases, Article, retina examination, diabetic retinopathy, retina disease, uveitis, retina blood vessel occlusion, sense organs, human
Abstract

Purpose To review the evolution and usefulness of ultra widefield images of the retina. Method Literature review. Results The ability to obtain images of the ocular fundus is one of the greatest breakthroughs in our specialty. This ability has refined over time, from obtaining images with a field of 30 degrees, to obtaining images that exceed 150 degrees using equipment such as the Optos Daytona (Optos, Dunfermline, United Kingdom) or the Heidelberg Spectralis (Heidelberg Engineering, Heidelberg, Germany). These images are extremely useful to evaluate diseases such as diabetic retinopathy, retinal vascular occlusions, pediatric retinal pathology, posterior uveitis, and even diseases which classically affect the macula such as age-related macular degeneration. Conclusion Ultra widefield images of the retina have revolutionized the way we study and understand retinal pathology. As technology for obtaining these images becomes more accessible, it will surely become part of the routine evaluation of retinal diseases. © 2016 Sociedad Mexicana de Oftalmología

Published
2017

3. Characterization of retinal vascular and neural damage in a novel model of diabetic retinopathy

Author

Weerasekera, L.Y., Balmer, L.A., Rams, R., Morahan, G., Weerasekera, L.Y., Balmer, L.A., Rams, R., and Morahan, G.

Abstract

Purpose. Diabetic retinopathy (DR) is a major cause of blindness globally. Investigating the underlying mechanisms of DR would be aided by a suitable mouse model that developed key features seen in the human disease, and did so without carrying genetic modifications. This study was undertaken to produce such a model. Methods. Our panel of Collaborative Cross strains was screened for DR-like features after induction of diabetes by intravenous injection with alloxan or streptozotocin. Both flat-mounted whole-retina and histologic sections were studied for the presence of retinal lesions. Progression of DR was also studied by histologic examination of the retinal vascular and neural structure at various time points after diabetes onset. In addition, microarray investigations were conducted on retinas from control and diabetic mice. Results. Features of DR such as degenerated pericytes, acellular capillaries, minor vascular proliferation, gliosis of Müller cells, and loss of ganglion cells were noted as early as day 7 in some mice. These lesions became more evident with time. After 21 days of diabetes, severe vascular proliferation, microaneurysms, preretinal damage, increased Müller cell gliosis, and damage to the outer retina were all obvious. Microarray studies found significant differential expression of multiple genes known to be involved in DR. Conclusions. The FOT_FB strain provides a useful model to investigate the pathogenesis of DR and to develop treatments for this vision-threatening disease

Published
2015

4. Characterization of retinal vascular and neural damage in a novel model of diabetic retinopathy

Author

Weerasekera, L.Y., Balmer, L.A., Rams, R., Morahan, G., Weerasekera, L.Y., Balmer, L.A., Rams, R., and Morahan, G.

Abstract

Weerasekera, L.Y., Balmer, L.A., Ram, R., Morahan, G. (2015). Characterization of retinal vascular and neural damage in a novel model of diabetic retinopathy. In Investigative Ophthalmology and Visual Science, 56(6), 3721-3730. Available here.

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