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Resource depletion is one of the primary concerns of modern agriculture farmers, which needs to be considered for long term sustainability. To assess the effect of sesame stalk compost on the growth, yield, and quality of sesame under organic cultivation, long-term (four years) field experiments were conducted for eight seasons consecutively from 2020 to 2023. The inoculated composts collected after 90 days of composting contain N (1.45–1.50%), P (0.22–25%), K (0.23–0.25%), Fe (510–514 ppm), Zn (150–154 ppm), Cu (286–288 ppm), and Mn (540–542 ppm), which was higher than the uninoculated sesame stalk. Similarly, the humic acid content (122 mg/g of compost), fulvic acid (23–24 mg/g of compost), total humic substances (145–146 mg/g of compost), and CO2–C evolution (186–188 mg/100 g of compost) were significantly higher with microbial inoculated composts than uninoculated compost. The results of the long-term field experiment indicated that application of sesame stalk compost @ 5 t/ha significantly increased the soil organic carbon (6.30 g/kg), soil organic carbon (SOC) stock (11.8 mg/ha), raised the pH to neutralize the acidic pH in red lateritic soil (6.8 to 7.2), reduced the soil bulk density (1.38 to 1.34), penetration resistance (720 kpa to 630 kpa), and available N, P, and K. As a result, the sesame grain yield obtained with application of sesame stalk compost @ 5 t/ha (778–782 kg/ha) was comparable with recommended doses of chemical fertilizers (794 kg/ha). Significant improvement in grain quality (24.2% of protein, 418–422 ppm of Ca, 12.4–12.6 ppm of Zn, 9.6 ppm of Fe and 2.6 ppm of Cu) and oil yield (364.1–367.5 kg/ha) was also observed due to the application of microbial inoculated sesame stalk compost. [ABSTRACT FROM AUTHOR]

Oxidative stress is recognized as a critical contributor to the advancement of neurological diseases, thereby rendering the alleviation of oxidative stress a pivotal strategy in the therapeutic management of such conditions. Sesamol, the principal constituent of sesame oil, has been the subject of extensive research due to its significant antioxidant properties, especially its ability to effectively counteract oxidative stress within the central nervous system and confer neuroprotection. While sesamol demonstrates potential in the treatment and prevention of neurological diseases, its modulation of oxidative stress is complex and not yet fully understood. This review delves into the neuroprotective effects arising from sesamol's antioxidant properties, analyzing how its antioxidative capabilities impact neurological diseases. It provides a theoretical foundation and unveils potential novel therapeutic applications of sesamol in the treatment of neurological disorders through the modulation of oxidative stress. [ABSTRACT FROM AUTHOR]

The production of edible plant seed oil used in the food industry is increasing globally. More than 75% of lipids in the human diet come from edible vegetable oils. Among them, sesame oil has the highest resistance to oxidation, valuable physiological properties, and a unique flavor and aroma. However, sesame oil is more expensive than rapeseed oil, and often both oils are mixed to reduce costs. In this study, we performed a physical and physico-chemical analysis of sesame oil and sesame/rapeseed oil mixtures (5/95, 10/90, 30/70, 50/50, 70/30 and 90/10 w/w). The investigated oils were characterized based on their fatty acid composition, peroxide value, iodine value, phase transitions, refractive indices, color and UV–Vis adsorption. The fatty acid composition of mixtures made from sesame and rapeseed oils depended on the ratio of the two oils. Increasing the content of sesame oil in the mixtures resulted in a decrease in the levels of oleic and linolenic acids, while the levels of linoleic acid increased. A very good linear correlation was observed between the temperatures and enthalpies of crystallization of the mixtures, which could be used to establish the composition of a mixture between sesame and rapeseed oil. Information about these parameters could increase the possibilities for the commercial use of the investigated oils. [ABSTRACT FROM AUTHOR]

Objectives: To compare the plaque reducing efficacy of oil pulling with sesame oil compared to distilled water in a randomized, controlled, examiner-blinded parallel group study. Materials and methods: Forty probands without advanced periodontal disease of the University Hospital for Restorative Dentistry and Periodontology, Medical University of Innsbruck (Austria) were randomized allocated to test- (sesame oil) or control group (distilled water) and asked to pull daily in the morning for eight weeks with their allotted fluid for 15 min. Rustogi Modified Navy Plaque Index (RMNPI) and gingival bleeding index were assessed at baseline and after four and eight weeks. Plaque samples underwent microbiological analysis. Results: Pulling with sesame oil was significantly more effective in reducing full mouth RMNPI compared to distilled water after eight weeks (median reduction 18.98% versus 10.49%; p = 0.023), and was most pronounced in anterior, buccal, and lingual subscales. On approximal surfaces, significantly higher plaque reduction was found in the test group after four (24.07% versus 14.29%) and eight weeks (16.00% versus 5.36%) of intervention (p < 0.05). No significant changes in gingival index and mirobiological analysis could be detected. Conclusion: Plaque reduction was statistically significantly higher with oil pulling than with distilled water, however, a study bias cannot be ruled out. Further high-quality trials are needed to understand the mechanisms and effectiveness of oil pulling, to finally clarify the evidence. Clinical relevance: Oil pulling may be recommended as an adjuvant to mechanical dental cleaning. Individuals with keratosis may experience adverse effects. Trial registration: ClinicalTrials.gov NCT06327841. [ABSTRACT FROM AUTHOR]

In this article, we present a unique system for identifying edible oils through the analysis of their thermophysical properties. The method is based on the use of active infrared thermography. The heating of the oils results from the optical absorption of laser radiation at a specified wavelength. This approach enables greater selectivity in differentiating between various types of edible oils, as the results depend not only on the thermal properties of the specific oils but also on their optical properties, which are uniquely characteristic of each oil. Additionally, the developed system provides a detailed visualization of spatial temperature gradients within the sample's volume, as well as their changes over time. It overcomes the limitations of other methods that determine only the thermal conductivity coefficients of oils through resistive heating of the sample. In this article, four types of vegetable oils (extra virgin olive oil, sesame oil, sunflower oil, and rapeseed oil) have been studied. Fatty acid analysis, differential scanning calorimetry, and UV-VIS spectroscopy have been used to determine the authenticity, moisture content, and optical properties of the studied samples. The developed system allows for the visualization and determination of the emerging temperature gradients in the sample volume. [ABSTRACT FROM AUTHOR]

Background: Plant oil extract like sesame oil has high polyunsaturated fatty acids, while palm oil extracts are saturated. A serial substitution of crude sesame extract together with crude palm extract was used in novel diets of African catfish. Five types of feeds designated as feed F1 to feed F5 were made to vary in the inclusion of crude sesame extract (CSE) and crude palm extract (CPE), CSE: CPE), as follows: F1, 25:5, F2, 20:10, F3, 15:15, F4, 10:5, and F5, 5:25. Feed F6 was a commercial feed. The fish were fed to satiation for 70 days. We analyzed the digestibility of CSE, CPE, the feeds and the hematology and hematobiochemical parameters of the catfish. Results: Results showed that the catfish had significantly higher digestibility for CSE 93.34 ± 0.22% than for CPE 78.98 ± 0.11%. Feed F1 had the highest digestibility 91.32 ± 0.07%, followed by feed F2, 82.25 ± 0.04%. The higher digestibility of feeds F1, F2, and F3 than F4 and F5 could be due to the lipids and fatty acid composition of the feed. Sesame seed is known to be high in phospholipids and triacylglycerols, and this enhances digestibility. Phospholipids are present in low quantities in palm oil. Crude sesame extract reduced blood cholesterol, triglycerides, and glucose, while crude palm extract increased them. Conversely higher dietary inclusions of CSE (F1 > F2 > F3) in that order increased the Hb, RBC, MCH, MCHC, TWBC, and the PCV.a Conclusions: Crude sesame extract should be added to the diets of African catfish for optimal digestibility and enhanced hematobiochemical and hematological indices. Crude palm extract should be added but not above 10% for optimal performances. [ABSTRACT FROM AUTHOR]

Several methods of altering rat models of Alzheimer disease (AD) have been developed, which have greatly facilitated the evaluation of novel therapeutic approaches to AD. In this study, a single radiation dose of 8 Gy was used as an induction method for AD-like symptoms owing to AB plaques increment in rat brain. This study was aimed at evaluating ionizing radiation as a rat model for AD-like symptoms through the neurobehavioral, biochemical. and histopathological investigations, in addition to the possible ameliorative role of sesame oil (SO). Animals were divided into control, AD-irradiated animals, SO-treated group, and AD + SO animals irradiated then treated with SO group. Rat brain cortex recorded significant elevations of hepcidin, β-secretase, TNF-α, ROS, and IL-6 levels as well as Fe level after radiation exposure in comparison with the control group. In addition, Zn and Cu levels recorded significant decreases compared with the control level. SO administration and irradiation significantly reverse the elevation of hepcidin concentration, β-secretase activity, and TNF- α level, whereas ROS and IL-6 levels showed some degree of improvement and their levels significantly decreased compared with the irradiated group. The behavioral impairments caused in AD resembling the symptoms group were significantly ameliorated by SO. Furthermore, histopathological studies supported the notion that SO markedly reduces the toxicity of radiation exposure. Findings indicate that radiation may be used as an induction method for AD disease owing to its oxidative stress ability. Furthermore, SO is considered a promising therapy for memory-loss complications according to the free radicals' defense of their unsaturated fatty acids on the neuron membrane. [ABSTRACT FROM AUTHOR]

Curcuma zedoaria (Christm.) Roscoe is a curcuminoid‐rich plant with potential applications in cosmetic products. This study aimed to optimize the microwave‐assisted extraction (MAE) conditions for C. zedoaria rhizomes using castor oil and sesame oil as solvents. A full factorial design was employed, investigating microwave power levels of 600 and 800 W, and microwave times of 30 and 90 s. The results showed that microwave time significantly affected extraction yield, and individual and total curcuminoid content while microwave power did not. The optimal conditions for maximizing extraction yield and total curcuminoid content were 600 W for 90 s with castor oil, and 600 W for 80 s with sesame oil. Stability testing revealed that curcuminoids were more stable in castor oil than in sesame oil when stored at 4°C, 30°C/75% relative humidity (RH), and 40°C/75% RH over 3 months. In conclusion, this study demonstrates that MAE is an effective method for extracting curcuminoids from C. zedoaria, with castor oil showing superior preservation of curcuminoid content. These findings suggest that castor oil could be a preferable solvent for the extraction and stabilization of curcuminoids in C. zedoaria for cosmetic applications. [ABSTRACT FROM AUTHOR]

Objective(s): Alzheimer's disease (AD) is a major public concern and one of the primary types of dementia characterized by memory impairment and cognitive decline. Although the properties of exercise training and cannabidiol (CBD) treatments for improving AD have recently been revealed, the exact mechanisms remain unknown. Therefore, this study highlights the interactive impact of high-intensity interval training (HIIT) and CBD administration on improving cognitive impairment in a rat model of amyloid beta (Aβ)-induced AD through modulating the expression of apolipoprotein E (APOE), presenilin-1, and glutamate proteins. Materials and Methods: After acclimatization, the animals were randomly assigned into seven subgroups: control (CNT), Sham, Alzheimer (AL), Alzheimer + HIIT (AL + HIIT), Alzheimer + cannabidiol (AL + CBD), Alzheimer + CBD + HIIT (AL + CBD + HIIT), and model (sacrificed ten days after surgery to confirm the induction of AD) groups. To induce AD, rats received an intrahippocampal injection of Aβ. The animals in exercise groups performed the HIIT protocol, and the rats in CBD groups were administered 20 mg/kg CBD suspended in sesame oil for six weeks. Following the experimental protocol, serum and hippocampus tissue were collected for histopathological and western blot analysis. Results: Our findings indicated that both HIIT and CBD treatments were efficacious in ameliorating Aβ deposition and modulating biomarkers of AD, including APOE, presenilin-1, and glutamate. However, the interactive effect of HIIT and CBD supplementation was more effective. Conclusion: Our findings demonstrated the positive therapeutic effect of HIIT and CBD interventions, particularly HIIT combined with CBD, on alleviating AD. [ABSTRACT FROM AUTHOR]

Opuntia ficus-indica is a subtropical fruit rich in dietary fibers, carotenoids, vitamins, minerals, and polyphenols. To substitute synthetic additives, its extracts could become an interesting proposal to preserve quality while adding desirable characteristics to meat products. This study aimed to develop healthier chicken patties (with a structured animal fat replacer) added with prickly pear extract (PPE). The extract was analyzed for total phenolic content and antioxidant activity (FRAP, ABTS, DPPH, and ORAC). Four chicken patty formulations were manufactured with total replacement of animal fat by sesame oil emulsion: control, erythorbate 500 ppm, PPE 500, and PPE 750 ppm. Proximate composition and fatty acid profile were analyzed on day 1, and pH, color, and lipid oxidation on days 1, 4, 8, 12, and 16. PPE treatments showed lower TBARSs (p < 0.05) and greater pigment stability at the end of storage, corroborating its potential to delay oxidation reactions. No significant effects on chemical composition, pH, or fatty acid profile were observed (p > 0.05). Unsaturated represented 76.2% of total fatty acids. Therefore, PPE is an effective antioxidant by improving oxidative stability without promoting changes in other properties, besides adding cleaner label approaches and the use of natural ingredients to develop meat products reformulated with unsaturated oils. [ABSTRACT FROM AUTHOR]

Based on the trade data of specific oilseed crops from 2002 to 2021, this paper analyzes the trade characteristics of sunflower seeds, sesame seeds and oil flax seeds by using GL index, BI index and Thom & McDowell index, and then summarizes the main forms of specific oilseed crops industry trade in China. The influencing elements of intra-industry trade are examined using a panel Tobit model, and appropriate countermeasure recommendations are made to ensure the security of China's specific oilseed crops business. The results indicate that in recent twenty years, the trade of China's specific oilseed crops industry is mainly inter-industry trade, and it is the primary source of trade increment. In the composition of intra-industry trade, the level of vertical intra-industry trade is greater than that of horizontal intra-industry trade. Through the empirical analysis of the factors affecting intra-industry trade, it is known that the differences in consumption preferences, products and trade distance have a significant impact on intra-industry trade of specific oilseed crops. In order to improve the trade level of China's specific oilseed crops industry, stabilize inter-industry trade and promote intra-industry trade, it is suggested that comprehensive measures should be taken to improve the domestic effective supply level of specific oilseed crops, implement differentiated development strategy, enhance the anti-risk ability and international competitiveness of China's specific oilseed crops industry, coordinate the effective connection between industrial policy and trade policy, ensure the safety of China's specific oilseed industry and promote its healthy and sustainable development. [ABSTRACT FROM AUTHOR]

Approximately 7% of children live with food allergy, a condition that requires dietary avoidance to prevent an allergic reaction. In this qualitative study, we aimed to understand food allergy-related experiences, beliefs and learning preferences among children with and without food allergies, to inform a school-based, food allergy education program. Data were analysed thematically. We virtually interviewed children in Kindergarten-Grade 8 in Manitoba, Canada, with (n = 7) and without (n = 9) parent-reported, physician-diagnosed food allergies. We identified three themes: Naive reliance on peers and school staff to assist with food allergy management; Limited food allergy knowledge; and, Recommended food allergy curricula: complementary perspective. Our findings will help inform the development of a school-based, food allergy education program, with a long-term goal of minimizing food allergy-related worries and optimizing safety for children with food allergy. Ongoing, school-based food allergy education is needed. [ABSTRACT FROM AUTHOR]

The by-product of extracting oil from sesame has good functional properties for use in the development of new food products. In this study, the effect of simulated gastrointestinal digestion on the bioaccessibility of phenolic compounds, as well as the antioxidant, antidiabetic, and hypoglycemic properties of a beverage from sesame by-products was analyzed. Oral digestion significantly decreased the total phenolic content of the beverage, while the total flavonoid content increased. Both phytochemicals increased after gastric and intestinal digestion. Twenty-five phenolic compounds were characterized in the sesame by-product beverage, including feruloylquinic acid, which was present in all the digestive fractions analyzed. The most abundant free phenolic was quercetin, which was also present in all the digested fractions. On the other hand, the most abundant phenolic in the digested fractions was isorhamnetin. During gastrointestinal digestion, the antioxidant activity and inhibitory effects on the α-glucosidase and DPP-IV of the beverage significantly improved, while the ability to inhibit the α-amylase significantly increased during oral digestion, remaining constant throughout digestion. Correlation analysis indicated that flavonoids, including quercetin, may be the compounds with the greatest effect on the evaluated activities. The results of this study not only improve the understanding of the impact of gastrointestinal digestion on the bioaccessibility of phenolic compounds but also suggest potential applications in formulating functional foods with enhanced antioxidant, hypoglycemic, and antidiabetic properties, contributing to the development of health-promoting food products. [ABSTRACT FROM AUTHOR]

Abstract Background Plant oil extract like sesame oil has high polyunsaturated fatty acids, while palm oil extracts are saturated. A serial substitution of crude sesame extract together with crude palm extract was used in novel diets of African catfish. Five types of feeds designated as feed F1 to feed F5 were made to vary in the inclusion of crude sesame extract (CSE) and crude palm extract (CPE), CSE: CPE), as follows: F1, 25:5, F2, 20:10, F3, 15:15, F4, 10:5, and F5, 5:25. Feed F6 was a commercial feed. The fish were fed to satiation for 70 days. We analyzed the digestibility of CSE, CPE, the feeds and the hematology and hematobiochemical parameters of the catfish. Results Results showed that the catfish had significantly higher digestibility for CSE 93.34 ± 0.22% than for CPE 78.98 ± 0.11%. Feed F1 had the highest digestibility 91.32 ± 0.07%, followed by feed F2, 82.25 ± 0.04%. The higher digestibility of feeds F1, F2, and F3 than F4 and F5 could be due to the lipids and fatty acid composition of the feed. Sesame seed is known to be high in phospholipids and triacylglycerols, and this enhances digestibility. Phospholipids are present in low quantities in palm oil. Crude sesame extract reduced blood cholesterol, triglycerides, and glucose, while crude palm extract increased them. Conversely higher dietary inclusions of CSE (F1 > F2 > F3) in that order increased the Hb, RBC, MCH, MCHC, TWBC, and the PCV.a Conclusions Crude sesame extract should be added to the diets of African catfish for optimal digestibility and enhanced hematobiochemical and hematological indices. Crude palm extract should be added but not above 10% for optimal performances.

Abstract FADS1 rs174556 polymorphism influences on dietary fats metabolism and type 2 diabetes (T2DM). This study aimed to compare the effect of three oils of sesame, canola and sesame-canola on cardio metabolic factors across genotypes of rs174556 variant in patients with type 2 of diabetes. This study was a randomized triple-blind three-way cross-over clinical trial. 95 Subjects with T2DM replaced their regular dietary oil with sesame oil, canola oil, or sesame-canola oil for three 9-week phases and completed the study. There were three anthropometric measurements, blood sampling and biochemical assessments at the beginning, middle, and at the end of each phase for assessments. Genotyping was conducted using the polymerase chain reaction-restriction fragment length polymorphism (PCR–RFLP) method. In the crude model, there was an interaction between consumed oils and rs174556 variant on serum concentration of Apolipoprotein A-I (ApoA-1). During intake of sesame oil, lower levels of triglycerides (TG) were observed in individuals with TT genotype compared to C allele carriers’ allele, which remained significant in adjusted models. Compared to C allele carrier’s, the people with TT genotype experienced significant increase and decrease in serum levels of HDL and TG, respectively in adjusted models. Also, the subjects who consumed sesame-canola oil had lower serum concentrations of fasting blood glucose than those who received sesame and canola oils, regardless of used oils and genotypes. FADS1 Gene variant (rs174556) might modify cardiometabolic changes following dietary vegetable oils. Larger longitudinal studies especially randomized clinical trials are needed to clarify these associations.

In this work, the reductive hydroformylation of linseed and sesame oils was carried out successfully by using a rhodium catalyst precursor associated to triethylamine/N‐methylimidazole ligands combination. Interestingly, in the presence of triethylamine and N‐methylimidazole at a precise ratio with respect to rhodium, the isomerization reaction can be inhibited and control experiments realized on methyl linoleate and methyl linolenate have clearly shown that no conjugated products were formed. This new catalytic system is full of interest since the yields in alcohols, after 24 h, are equal to 21% and 15% for Rh/triethylamine combination, whereas equal to 58% and 63% for Rh/triethylamine/N‐methylimidazole combination, for linseed and sesame oils, respectively. [ABSTRACT FROM AUTHOR]

The current study aimed to investigate the effects of plant-mediated selenium nanoparticles (SeNPs) on plant growth, photosynthetic pigments, antioxidant activity, and the triacylglycerol profile of sesame (Sesamum indicum L.). The green synthesis of SeNPs was achieved using garlic extract, resulting in spherical nanoparticles with an average size range of 70–75 nm. Three SeNP treatments (T3, 30 ppm; T4, 40 ppm; and T5, 50 ppm) were applied through seed and foliar spray on six sesame varieties (V1, TS-5; V2, TH-6; V3, Til-18; V4, Niab Millennium; V5, Niab Pearl; and V6, NS-16). All enzymatic antioxidant parameters showed an increase in the treated groups, such as SOD (74.4% in V1 at T4), POD (43% in V5 at T5), APX (62% in V1 at T3), and GPX (31.56% in V3 at T4). CAT showed the highest percentage improvement in T5 for V1, V2, V4, and V5, while V3 and V4 exhibited the highest values at T4. Likewise, seed antioxidant parameters also showed increase in antioxidant activity, highest total phenolic content (6.06 mg GAE/g) was found at T5 treatment with percent increase of 27.41%, but the highest percent increase was found to be at T4 treatments in V1 with increase of 46.83%. Percent oil yield was also noted to be higher as highest percent (60%) oil yield was obtained at T4 treatment in V3. Ultra High Performance Mass-Spectrometry (UHPLC-MS) analysis and chemometric modeling suggested a total of 10 triacylglycerol (TG) biomarkers separating untreated groups, with higher relative abundance values at T4 and T5 treatments compared to control. PCA and correlation analysis showed clustering of untreated groups from T4 and T5, which suggests that these two treatments result in higher accumulation of oil. A generalized linear model with ANOVA showed a highly significant impact of treatments on all the growth and oil parameters, with significance involvement of varieties. The interaction between variety and treatment showed no significant effect on the growth and oil biomarkers of sesame. However, it can be concluded that the T4 and T5 treatments (40 ppm and 50 ppm) of SeNPs, applied through seed and foliar methods, have a strong influence on the overall growth and oil yield of sesame. This warrants further transcriptomic and molecular analysis to gain deeper insight into the mechanisms of action of SeNPs. [ABSTRACT FROM AUTHOR]

Introduction: Exposure to fine particulate matter (PM2.5) is known to be associated with cardiovascular diseases. Sesamin (Ses) is a natural phenolic compound found in sesame seeds and sesame oil. Ferroptosis is a novel mode of cell death characterised by iron-dependent lipid peroxidation. This study aims to explore whether PM2.5 can induce ferroptosis in H9C2 cells and to investigate the precise protective mechanism of Ses. Methods: Based on transcriptomic data, PM2.5 may induce ferroptosis in cardiomyocytes. The ferroptosis inducer erastin and ferroptosis inhibitor ferrostatin-1 (Fer-1) were used to illustrate the mechanisms involved in PM2.5-induced H9C2 cell injury. Using network pharmacology, the pharmacological mechanism and potential therapy targets of Ses were explored for the treatment of PM2.5-induced cardiomyocyte injury. H9C2 cells were cultured and pretreated with Fer-1 or different concentrations of Ses, and then cardiomyocyte injury model was established using erastin or PM2.5. Indicators of oxidative responses, including total superoxide dismutase, reduced glutathione, glutathione peroxidase and malondialdehyde, were measured. The expression levels of ferroptosis-related proteins were determined through Western blot analysis. Results: Results demonstrate that PM2.5 induces ferroptosis in H9C2 cells and Ses exerts a protective effect by suppressing ACSL4-mediated ferroptosis. Discussion: Overall, these findings elucidate a novel mechanism by which Ses ameliorates the detrimental effects of PM2.5 on cardiomyocytes. [ABSTRACT FROM AUTHOR]

BACKGROUND RESULTS CONCLUSIONS The aqueous extraction of sesame oil is a traditional process that generates a large amount of melanoidins. However, little is known about the characteristics and bioactive functions of these melanoidins.Electronic tongue, fluorescence emission spectroscopy, and Fourier transform infrared spectroscopy analyses indicated that melanoidins from sesame residues (MELs) are brown macromolecular compounds with protein skeletons and heteroaromatic ring structures, a bitter taste, and instability in strong oxidative and reductive environments. The MELs demonstrated inhibitory effects on α‐glucosidase, α‐amylase and pancreatic lipase in vitro. These MELs mitigated weight loss in mice with type 2 diabetes (T2DM), reduced their fasting blood glucose to 54.73% (500 mg kg−1 day−1) of the initial value, increased the glycogen levels in the liver and skeletal muscles, lowered blood lipid levels, and protected the liver. Western blot analysis revealed that MELs inhibited the activities of enzymes such as PEPCK, FBPase, and G6Pase through the IRS‐1/PI3K/Akt and AMPK pathways, increased the activity of the enzymes hexokinase (HK) and pyruvate kinase (PK), enhanced liver glycolytic ability, and promoted liver glycogen synthesis, thereby reducing blood glucose levels in T2DM mice. Moreover, MELs reduced the ratio of Firmicutes to Bacteroides (F/B) in the intestines of T2DM mice, increased the relative abundance of beneficial bacteria such as Lactobacillus, Coprococcus, and Ruminococcus, and reduced the propionic acid content.Melanoidins can regulate T2DM by activating the IRS‐1/PI3K/Akt and AMPK‐signaling pathways and ameliorating gut microbiota imbalances in T2DM mice. © 2024 Society of Chemical Industry. [ABSTRACT FROM AUTHOR]

Oxidation of fats in food greatly reduces their shelf life and causes food of unacceptable quality to be presented to the customer. In this regard, this research was conducted with the aim of increasing the oxidative stability of sesame oil with nanoliposomes containing the antioxidant extract of yarrow plant. In this study, 6 concentrations of nanoliposomes containing yarrow plant extract (0, 50, 100, 200, 500 and 1000 ppm) were used in sesame oil, and tests such as acidity, peroxide, thiobarbituric acid index, conjugate diene were performed on those oils. And after finding the best concentration of nanoliposome containing yarrow extract, this sample was compared with the sample containing the same amount of free yarrow extract and also the sample with 200 ppm BHT after 7 days of storage at 63 degrees Celsius. The results showed that with increasing storage time, acidity level, thiobarbituric acid index and conjugate diene increased, but with the increase of nanoliposome containing 500 ppm of yarrow extract, these characteristics decreased and then increased. Unlike other characteristics, the peroxide content of the samples decreased from the 5th day onwards. On the other hand, it was found that the sample containing 500 ppm of free yarrow extract had the highest level of acidity, peroxide, thiobarbituric acid index and conjugate diene. The highest oxidative stability (14.21 hours) belonged to the oil with nanoliposome containing 500 ppm of yarrow extract. The dominant fatty acid in sesame oil containing nanoliposome as well as control was linoleic acid, and the use of antioxidants did not significantly change the fatty acid profile of sesame oil. Finally, it can be stated that the use of nanoliposome containing yarrow plant extract is a suitable alternative for synthetic antioxidants available in the market [ABSTRACT FROM AUTHOR]

Diglycerol (DAG) is a structural lipid with the functions to lower body fat accumulation and decrease serum triglyceride level. However, the enzymatic synthesis of DAG is limited by the high-efficient and economic lipases. In this paper, the immobilized lipase PS@LXTE-1000 was self-made by immobilizing the Pseudomomas cepacian lipase on to the hydrophobic microporous resin LXTE-1000. The results indicate that LXTE-1000 was a uniform mesoporous sphere with the mean diameter of 400 µm, pore size of 14.6 nm, pore volume of 0.5 cm³/g and surface area of 126.0 m²/g, showing superior structural properties for lipase immobilization. Under the optimal reaction conditions with the molar ratio of rapeseed oil to glycerol being 1:1, adding amount of immobilized lipase being 4%, reaction at 50 °C, the highest DAG content of 46.7% was achieved in 3 h via enzymatic glycerolysis catalyzed by LXTE-1000. After 7 cycles of reuse, the self-made LXTE-1000 could still retain 78.3% of its initial catalytic ability. Besides, LXTE-1000 was observed to facilitate the DAG production via glycerolysis reaction between glycerol with other seven edible oils including corn oil, sesame oil, peony seed oil, rice bran oil, peanut oil, soybean oil and flaxseed oil. Specifically, the glycerolysis reaction with sesame oil, peony seed oil and rice bran oil even led to the DAG content of 52.1%, 53.3% and 51.2%, respectively, Hence, this paper provide a novel strategy to produce high-efficient and economic immobilized lipases, which shows great potential in the green synthesis of functional lipids such as DAG. [ABSTRACT FROM AUTHOR]

Nickel and titanium (NiTi) based shape memory alloys (SMAs) are novel materials endowed with exceptional super-elasticity, corrosion resistance, and shape memory capabilities, making them well-suited for biomedical and industrial applications. The current study explores the impact of process parameters in powder mixed micro-electrical discharge milling (µ-EDM) on NiTi SMA, focusing on pulse on time (TON), voltage, pulse off time (TOFF), and RPM individually, employing a one factor at a time (OFAT) methodology to analyze surface characteristics, surface roughness (Ra), and material removal rate (MRR). The impact of black phosphorus powder combined with sesame oil (dielectric) on the surface of fabricated channels in commonly used biomaterials was investigated. The cytotoxicity test for biocompatibility was carried out to enhance the cell viability up to 79.89% after machining, which showed enhanced cell viability. The highest MRR the lowest Ra were obtained at the best input factors combination of 24 µs (TON), 6 µs (TOFF), 240 V, and 50 RPM tool rotation. Improved micro-channel quality was observed with lower TON, voltage, and RPM. [ABSTRACT FROM AUTHOR]

This study aimed to investigate how varying cooling rate impacts the characteristics of oleogels prepared using a sesame oil and rice bran oil blend (5:6, w/w) using a combination of beeswax and stearic acid (3:1, w/w at 12%, w/w) as the oleogelators. The study assessed three different cooling rates—0.5, 1.5, and 5 °C/min—with a focus on the attributes of the oleogels. The study revealed that the cooling rate had a substantial impact on the strength of the gel network. The cooling rate of 0.5 °C/min resulted in a higher oil-binding capacity and a stronger gel structure than fast cooling. The thermal properties and molecular interactions of the oleogels were not influenced by the cooling rate. The findings of this study indicated that the characteristics of beeswax and stearic acid oleogel prepared using sesame oil and rice bran oil blend could be tailored by manipulating the cooling rate. [ABSTRACT FROM AUTHOR]

The article focuses on the development of a sesame oil nanoemulsion encapsulated with maltodextrin and acacia gum using a spray-drying method to enhance its stability and functionality. Topics include the physicochemical properties of the encapsulated nanoemulsion, the high encapsulation efficiency achieved, and the potential applications of this method in the food and pharmaceutical industries.

Consumer use of cannabidiol (CBD) is growing, but there are still data gaps regarding its possible adverse effects on reproduction and development. Multiple pathways and signaling cascades involved in organismal development and neuronal function, including endocannabinoid synthesis and signaling systems, are well conserved across phyla, suggesting that Caenorhabditis elegans can model the in vivo effects of exogenous cannabinoids. The effects in C. elegans on oxidative stress response (OxStrR), developmental timing, juvenile and adult spontaneous locomotor activity, reproductive output, and organismal CBD concentrations were assessed after exposure to purified CBD or a hemp extract suspended in 0.5% sesame oil emulsions. In C. elegans, this emulsion vehicle is equivalent to a high-fat diet (HFD). As in mammals, HFD was associated with oxidative-stress-related gene expression in C. elegans adults. CBD reduced HFD-induced OxStrR in transgenic adults and counteracted the hypoactivity observed in HFD-exposed wild-type adults. In C. elegans exposed to CBD from the onset of feeding, delays in later milestone acquisition were irreversible, while later juvenile locomotor activity effects were reversible after the removal of CBD exposure. CBD-induced reductions in mean juvenile population body size were cumulative when chronic exposures were initiated at parental reproductive maturity. Purified CBD was slightly more toxic than matched concentrations of CBD in hemp extract for all tested endpoints, and both were more toxic to juveniles than to adults. Dosimetry indicated that all adverse effect levels observed in C. elegans far exceeded recommended CBD dosages for humans. [ABSTRACT FROM AUTHOR]

Rice bran oil is recommended by the World Health Organization as one of the three major healthy edible oils (along with corn and sesame oils), owing to its unique fatty acid composition and functional components. This study screened, organized, and analyzed a large number of studies retrieved through keyword searches, and investigated the nutritional value and safety of rice bran oil. It reviews the stability of raw rice bran materials and the extraction and refining process of rice bran oil and discusses food applications and sub-health regulations. Research has found that a delayed stabilization treatment of rice bran seriously affects the overall quality of rice bran oil. Compared with traditional solvent extraction, the new extraction technologies have improved the yield and nutritional value of rice bran oil, but most of them are still in the research stage. Owing to the lack of economical and applicable supporting production equipment, extraction is difficult to industrialize, which is a challenging research area for the future. Rice bran oil has stronger antioxidant stability than other edible oils and is more beneficial to human health; however, its application scope and consumption are limited owing to the product price and lack of understanding. Rice bran oil has significant antioxidant, anti-inflammatory, anti-cancer, hypoglycemic, lipid-lowering, and neuroprotective effects. Further exploratory research on other unknown functions is required to lay a scientific basis for the application and development of rice bran oil. [ABSTRACT FROM AUTHOR]

Fragrant edible sesame oil is popular for its unique aroma. The aroma of sesame oil is determined by its volatile organic compound (VOC) profile. Sesame oils produced by different techniques could have different VOC profiles. In addition, blending fragrant sesame oil with refined oil could also alter the VOC profile of the final product. Current practices in aroma analysis, such as sensory evaluation and gas chromatography (GC), still face many restraints. Hence, there is a need for alternatives. We present a novel 14-unit multiplexed paper-based colorimetric sensor for fragrant sesame oil VOC analysis. The sensor was designed to visualize the VOC profile as a color "fingerprint". The sensor was validated with 55 branded sesame oil samples produced by two different techniques, i.e., hot pressing and small milling; the experimental results suggested a processing dependency in color VOC fingerprints. The sensor also demonstrated the potential to detect the change in sesame oil VOC profile due to blending with refined oil, with an estimated limit of detection down to 20% v/v of the refined oil. The colorimetric sensor might be used as a simple, rapid, and cost-effective analytical tool in the production and quality control of fragrant sesame oil. [ABSTRACT FROM AUTHOR]

Sesamin, a lignan component of sesame seed oil, has shown pharmacologic benefits, such as anti-oxidative and anti-inflammatory qualities. However, the amount of data available to the field is surprisingly sparse, as for instance there is no known spectroscopic characterization of sesamin. This work provides the first experimental infrared spectrum of sesamin. Sesamin powder was subjected to experimental Fourier-transform infrared spectroscopy, and the resulting spectrum was compared to quantum chemical calculations of sesamin's stereoisomers in various hydration states. Major peaks of sesamin were assigned vibrational modes through comparison of computed and observed spectra. Multiple sesamin species may be present in a typical powder sample, coexisting with potential trace hydration. [ABSTRACT FROM AUTHOR]

Porous liquids (PLs) are a new type of fluid sorbent investigated mainly for the separation of gas mixtures. Here, we explore their application to the separation of miscible liquids, using MEG/water (MEG=monoethylene glycol) and EtOH/water as proof‐of‐principle. Recovery of used MEG is industrially important but its extraction into conventional solvents from water is difficult. PLs ZIF‐8@PDMS (PL1, PDMS=polydimethylsilicone) or ZIF‐8@sesame oil (PL2) each consisting of 25 wt % of the hydrophobic microporous material ZIF‐8 dispersed in PDMS or sesame oil respectively, were formulated and found to be exceedingly physically stable to sedimentation. A 5 nm PEEK membrane was used to provide a permeable barrier between the PL and the alcohol/water phase. MEG was selectively extracted through the membrane from approximately 50 : 50 wt % MEG/water mixtures into the PL phase and this procedure could be applied repeatedly. It was effective for MEG/water mixtures as dilute as 3 : 97 wt %. The PL could also be regenerated (80 °C at 0.01 bar) and re‐used, suggesting its potential for continuous, cyclic extraction. Furthermore, PL3 (silicalite‐1@PDMS) was effective in selective alcohol extraction from beverages. It shows potential for lowering the alcohol concentration in gin or wine due to its excellent chemical stability and nontoxicity. Overall, we show that the enhanced adsorption properties of PLs due the presence of empty pores, which provides unusually high gas solubilities, also makes them, in principle, applicable to liquid‐liquid separations. [ABSTRACT FROM AUTHOR]

Cookies are an exceptional energy source due to their elevated fat and carbohydrate content. Beyond their delectable taste, they are also rich in essential nutrients, including valuable proteins and minerals. This study evaluated the potential of the wheat variety NARC‐2011 for cookie production, focusing on nutritional enhancement by adding white sesame seeds at different proportions (5%, 10%, and 15%) to both whole and fine wheat flour. White sesame seeds were added to cookies mainly for their visual appeal, creating a nice contrast with the dough. They also have a mild flavor that complements the cookie without overwhelming it. Besides, they pack essential nutrients like protein, fiber, calcium, and iron, making the cookies more nutritious. The physical, chemical, and sensory properties of the different cookies were evaluated using standard methods. In terms of physical parameters, fine wheat flour cookies exhibited a diameter (46.45–50.47 mm), thickness (8.47–9.77 mm), and spreading factor (5.16–5.46 mm), and whole wheat flour cookies exhibited a diameter (48.47–52.31 mm), thickness (9.22–10.73 mm), and spreading factor (4.87–5.25 mm). Chemical analysis revealed moisture (5.78%–7.66%), fat (10.89%–16.16%), fiber (6.10%–8.46%), ash (4.82%–7.40%), protein (0.74%–1.40%), non‐fiber carbohydrates (63.67%–67.55%) for fine wheat flour cookies, and moisture (5.67%–7.39%), fat (10.89%–16.16%), fiber (11.47%–15.98%), ash (0.54%–0.83%), protein (5.65%–8.13%), non‐fiber carbohydrates (57.86%–66.55%), total phenolic content (2.86 mg/g), flavonoids (1.46 mg/g), and antioxidant activity (80.76%) in whole wheat flour cookies with sesame fortification. Gas chromatography revealed higher unsaturated fatty acids (83.22%) in NARC‐2011 wheat oil compared to white sesame seed oil (79.78%). In sensory evaluations, cookies fortified with 10% sesame seeds in fine wheat flour received the highest level of acceptability from the panelists. On the other hand, cookies made from whole wheat flour fortified with 15% sesame seeds garnered the maximum acceptability ratings from the panelists. In conclusion, supplementing NARC‐2011 wheat flour with sesame seeds, whether in fine or whole wheat form, improves the quality of cookies and nutritional content while offering appropriate sensory attributes at particular sesame seed levels. [ABSTRACT FROM AUTHOR]

One of the most basic needs of human beings in order to survive is nutrition. sesame, which is rich in protein, fiber, minerals, and vitamins, has a very high nutritional value. The oil obtained from sesame took its place among the oils used in ancient Mesopotamia to facilitate the cooking of meals and to increase their flavor. Sesame, which is of vital importance for ensuring daily energy requirements and maintaining a healthy lifestyle, was considered a sacred plant in Ancient Mesopotamian societies and was widely used in religious rituals. This situation shows that sesame was considered not only as a food source but also as a religious symbol. From a medical point of view, the health benefits of sesame cannot be ignored either. It is known that sesame has been used for various medicinal purposes since ancient times. In traditional medicine practices, sesame oil has been used for skin care, massage, and the treatment of certain diseases. In addition, it is known that sesame has antioxidant properties and some components it contains have positive effects on health. Therefore, it can be said that throughout history, sesame has both contributed to people's physical health and had a very important position from a cultural point of view. In the article, based on cuneiform sources, the use of sesame, one of the main food sources of Mesopotamian societies, in various fields such as nutrition, religion, food culture, and medicine is discussed. The purpose of this study is to examine the usage areas of sesame in Ancient Mesopotamia, which have made important contributions to the formation of the world's cultural heritage. [ABSTRACT FROM AUTHOR]

Background. Polycystic ovary syndrome (PCOS) is commonly associated with obesity and may be exacerbated by the lack of vitamin D3. Aim. The study aimed to investigate the effects of vitamin D3 administration in female rats with PCOS and prolonged high fat diet (HFD). Methods. Forty-four female Wistar rats, 180-200 g, 10 weeks old, were randomly allocated into 2 groups (n=22) that received a single dose intramuscular injection of: sesame oil (group I), or estradiol valerate (5 mg) in sesame oil (group II). After 4 weeks, intraovarian cysts developed in group II, as evidenced by ultrasonography. In the next step, half of rats from each group received standard diet (SD) and the other half high fat diet, through oral gavage, for 17 weeks, the following groups being obtained: Control (SD), HFD, PCOS (PCOS+SD) and PCOS+HFD. Next, all the rats received, for 5 weeks, 500 UI/kg/day vitamin D3, through oral gavage. Lipid peroxidation was assessed through malondialdehyde level in the ovary and periovarian tissue and the inflammation was quantified in ovary by NFkB, pNFkB, NRF2 and SOD1 expressions. Ovaries from all groups were collected for histopathological analysis. Blood samples were taken to evaluate the basal insulin, triglycerides and total cholesterol levels throughout the experiment. Results. Both groups with PCOS recorded significant increases of malondialdehyde in ovaries (p<0.001) and in periovarian tissue, especially in PCOS+HFD (p<0.05), even after vitamin D3 administration. PCOS+HFD group treated with vitamin D3 showed a high degree of inflammation in ovarian histopathology but with decreased pNFkB expression (p<0.01) while PCOS group recorded an increased SOD1 expression (p<0.05). Additionally, vitamin D3 treatment attenuated the insulin level (p<0.001) in PCOS and in HFD groups and the total cholesterol level in PCOS+HFD group, but triglycerides recordings were without statistical significance (p>0.05). HFD induced inflammation in ovaries, evidenced histologically and through increases of COX2 expressions (p<0.05) without significant influences on oxidative stress and on cholesterol levels. Conclusions. Polycystic ovary syndrome is associated with oxidative stress and inflammation in the ovary tissue and in blood with increased levels of insulin, total cholesterol and triglycerides that might be partially mitigated by vitamin D3 oral administration. [ABSTRACT FROM AUTHOR]

The main objective of the present trial was to examine the efficacy of feeding tilapia fry fish on Artemia franciscana diets supplemented with various oil emulsion resources in terms of performance, behavior indices, survival rate, blood biochemical parameters, and immunological response. Four hundred Nile tilapia fry (weighing 0.15±0.05 g and measuring 2.17±0.08 cm) were randomly allocated into four equal groups (each with five repetitions) and acclimatized for fifteen days. The first group served as the control and received unenriched Artemia franciscana (G0), while the remaining three groups were fed Artemia franciscana diets enriched with different oil resources (0.5 mL oil per liter for 6 hours): soybean oil (G1), sesame oil (G2), and rice bran oil (G3). Behavioral observations were recorded during the 45-day experimental period. At the end of the feeding trial, the chemical composition and fatty acid content of both Artemia and fingerlings were analyzed. Furthermore, the growth performance, survival, and immune response of the fingerlings were evaluated. The results indicated noticeable improvements in behavioral measurements (feeding, foraging and schooling), performance (final length, final weight, net weight gain, feed conversion ratio and specific growth rate), survival, and immune response among fry fish supplemented with enriched Artemia, particularly those enriched with soybean oil. Additionally, the chemical composition and fatty acid content of both Artemia and fish fry were significantly enhanced when oil emulsions are applied, with soybean oil demonstrating the most prominent improvements. Whereas, supplementing fry fish Artemia diets with oil resulted in lower liver enzyme activity and higher protein component levels in plasma in comparison to the control group. In brief, feeding Nile tilapia fry fish Artemia diets enriched with a soybean oil emulsion (0.5 mL/L) is recommended for promoting high performance, immunological activity, and survival throughout the early stage till fingerlings phase. [ABSTRACT FROM AUTHOR]

Summary: In this study, sesame hull oil (SHO) was extracted to characterise its composition. SHO was heated to determine the volatiles and their effect on the quality of cold‐pressed dehulled sesame oil (SO). Seventeen fatty acids, four lignans (1088.65 mg/100 g), tocopherols (284.17 mg/100 g) mainly in the γ‐form, and sterol (1722.16 mg/100 g, 4.67 times more than in sesame kernel oil) were detected in SHO. After heating, the volatiles found in SHO were mainly aldehydes and acids, represented by hexanal (fatty, green aroma) and 3‐methyl‐butanoic acid (fatty, rancid aroma), respectively. The acid value, peroxide value, anisidine value, and turbidity of SO increased significantly after adding SHO, and the scavenging ability of 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) was enhanced. The oxidation induction times of SO with the addition of SHO ranged from 8.93 to 9.53 h. The present study provides information about SHO and a new direction for the utilisation of sesame hulls. [ABSTRACT FROM AUTHOR]

This study investigates the use of a non-destructive ultrasonic pulse-echo method to characterize argan oil and other vegetable oils with similar fatty acid profiles. Ultrasonic parameters such as velocity, acoustic attenuation and reflection coefficient were measured across different temperatures. These parameters were used to create predictive models of ultrasonic velocity using partial least squares regression. Results demonstrated significant correlations between ultrasonic properties, oil temperature and fatty acid content. Specifically, ultrasonic velocity was found to be directly proportional to the content of saturated fatty acids and inversely proportional to the content of monounsaturated and polyunsaturated fatty acids. The reflection coefficient was also found to correlate with the fatty acid composition and temperature of the oils. Additionally, both ultrasonic velocity and acoustic attenuation decreased as the temperature increased from 25 °C to 50 °C. At 25 °C, the acoustic attenuation for argan oil was 22.37 Np/m, decreasing to 11.37 Np/m at 50 °C. These correlations allowed for the differentiation between food-grade argan oil, argan oil from seeds regurgitated by goats, sesame oil and peanut oil. The developed predictive models exhibited high coefficients of determination, with a value of 97.03 for argan oil, indicating strong agreement between measured and predicted ultrasonic velocities. This research highlights the potential of ultrasonic techniques for oil characterization and quality control. [ABSTRACT FROM AUTHOR]

The article explores eco-friendly methods for controlling leaf webber and capsule borer pests in sesame crops, emphasizing the importance of sesame as an oilseed crop and the challenges posed by insect pests. Botanical treatments such as azadirachtin and agniastra were found to be effective in reducing pest populations and damage, leading to higher seed yields. Economic analysis revealed that these treatments also provided the highest net realization and cost-benefit ratios, demonstrating their effectiveness in pest management and economic returns in sesame cultivation. The document includes data on the efficacy of botanical extracts, labor costs, prices of treatments, and references to previous studies on pest management in sesame crops, with no conflicts of interest declared by the authors. [Extracted from the article]