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BACKGROUND: Ultrasound is an important tool to diagnose many clinical conditions. Yet hand-held devices may be prone to more data variability in part from the greater likelihood of human error. OBJECTIVE: Quantify intra-rater reliability of subcutaneous skin fold thickness from a hand-held ultrasound device. PARTICIPANTS: College-age subjects (18 men, 14 women) submitted to two sets of ultrasound subcutaneous skin fold measurements spaced (mean + sem) 10.6 + 2.2 days apart. Per measurement, they stood relaxed as ultrasound measured the subcutaneous skin fold thickness that covered their left leg’s calf muscle group. Measurements occurred with a hand-held device (BodyMetrix Pro System BX2000; Livermore, CA) used in accordance with the manufacturer’s guidelines. Four subcutaneous measurements were made 90∘ apart (anterior, medial, posterior, lateral) at the portion of the left calf with the largest circumference. To assess intra-rater reliability, we used intraclass correlation coefficients, limits of agreement, coefficient of variation and the smallest real difference. RESULTS: Intra-rater reliability was high for most of our statistical tests. CONCLUSION: Despite the relatively long period between measurements, our hand-held ultrasound device exhibited a high degree of intra-rater reliability. Given our results, ultrasound measurements may be a useful tool to quantify skin fold thickness.

Body composition refers to body weight in terms of the absolute and relative amounts of muscle, bone, and fat tissues. Under graduate health science students are required to undertake various activities while pursuing their course so they are required to be fit. As a result, the students should be well aware of their body composition and how aerobic capacity varies on this basis. To study the effect of body composition on aerobic capacity and blood pressure in under graduate health science students. The objectives include estimation of Body composition by calculating body fat %, VO2 max after completion of Queen’s College Step Test, evaluating the blood pressure, resting & post QCST test protocol in under graduate health science students. 280 under graduate health science students able to complete QCST test were recruited. Documentation of demographic data and baseline parameters were done. Skin fold measurements at various sites were taken to estimate the body fat percentage. The QCST was done and Post-test recovery pulse rate and blood pressure were recorded. The post-test parameters were used to calculate the Vo2 max. The result of the study shows that there is an effect of body composition on aerobic capacity and blood pressure in under graduate health science students thereby supporting the aim of the study. It is clear that body composition does affect the aerobic capacity and blood pressure in undergraduate health science students. Furthermore it is to note that the fitness level of health science students are better if their body fat percentage is lower because they are exhibiting higher aerobic capacity and also the blood pressure values have found to be comparatively lower.

Objective: Aging causes major changes in body composition which is related with lower muscular strength and endurance, as well as mobility and walking. Increase in accumulation of adipose tissue and increase in body fat can cause a reduction in body balance, which is a key contributing factor to falls. Therefore, the purpose of this study is to find the influence of skin fold thickness on dynamic balance in older adults. Methods: A total of 49 community dwelling older adults aged 65 years and older were recruited in this cross-sectional study. Skin fold calliper and time up and go (TUG) test was used to measure the skin fold thickness and dynamic balance respectively. The Karl Pearson’s coefficient was used to estimate the relationship between the variables. Results: The Karl Pearson correlation co-efficient showed moderate positive correlation between skin fold thickness and TUG (r=0.395), which was found to be statistically significant (p

Introduction: Obesity is a chronic disease with excessive accumulation of body fat, exceeding the normal health level and affecting the physiological functioning of the body. Objective: To establish an obesity evaluation standard closely related to health based on sports medicine indexes, and to provide a new theory and method for the formulation of an obesity evaluation standard in China. Methods: Height, weight, skin fold thickness (shoulder, arm) and medical indexes (SBP, DBP, TC, TG, HDL, INS) of 108 female subjects in a city were tested by means of anthropometry, experiment, and mathematical statistics. All the selected medical indicators were evaluated according to clinical medical standards. Results: the body mass index of 108 women was positively correlated with such medical indexes as systolic blood pressure, diastolic blood pressure, triglycerides, high density lipoprotein cholesterol, insulin and so on (P

Objectives: Obesity is one of the important risk factors for peripheral arterial disease (PAD). Ankle-brachial pressure index (ABPI) is a non-invasive test, which may be used for earlier detection of PAD. ABPI in healthy obese/overweight subjects has not been studied. In present study, we investigated correlation of adiposity indices with ABPI. We have also compared ABPI by three different methods in healthy obese/overweight subjects. Materials and Methods: Weight, height, body mass index (BMI), waist circumference, hip circumference (HC), waist height ratio, waist hip ratio, skin fold thickness, and body fat percentage were measured in 45 healthy overweight/obese males. Ankle and brachial pressures were measured by Doppler ultrasound based method. ABPI was calculated using high ankle pressure (ABPI-HIGH), mean ankle pressure (ABPI-MEAN), and low ankle pressure (ABPI-LOW) methods. Results: BMI and HC show positive significant correlation with ABPI-LOW (P = 0.028, P = 0.046, respectively). Significant difference was observed between ABPI-LOW and ABPI-HIGH (P = 0.003). ABPI-MEAN and ABPILOW were also significantly different (P < 0.001). Conclusion: There is a correlation of obesity indices with ABPI-LOW. ABPI-LOW methods could be more appropriate method and contrastingly HC may have direct correlation with PAD detection by ABPI in apparently healthy obese.

The purpose of this study was to examine the influence of strength training on physical fitness and obesity of college girls. The selected (n = 70) participants were girls' students of Yazman, Bahawalpur. The selected variables were 600m race for endurance, 30m dash for speed, standing broad jump for leg power, zigzag run for agility, sit and reach for flexibility, and handgrip strength. The body composition was estimated through five skin folds, seven girths, three breadths, and the lengths of upper and lower limbs. Eight weeks training schedule was adopted, (five days in a week) which comprises of different physical activities such as a 400m race, sit-ups, skipping, matches of badminton and volleyball. A paired t-test was applied to examine the effect of training on body composition and physical fitness of college girls. The result showed that strength training significantly affects bicep skin fold, hip girth, chest girth, 30m race, and flexibility. It is concluded that strength training increases physical fitness and reduces the body fat of college girls. The comparative analysis results revealed that after eight-week strength training, the college girls' students become physically active, reduced body fats, and assist in weight management.

Aim: To determine General anthropometric data and dental caries and their association of paternal Individual Deprivation Measure among 12- to 15-year-old school going children in Tiruvallur District. Methods and Material: The Anthropometric data such as Body mass index, Skin fold thickness and mid arm circumference was assessed. The study was also conducted to assess children's paternal deprivation using individual deprivation index (IDM). Paternal deprivation was calculated using Individual deprivation index which comprises of 15 dimensions. Pilot study was done to calculate sample size which is found to be 800. Results: Dimension of paternal individual deprivation measure in parent Education, Housing, toileting, family planning, problem in visiting doctor between Government and Private School children was significant with P value of 0.0005. Interpretation of Paternal individual deprivation measure was found to be significant among Government and private school children. There was no association of individual deprivation measure with dental caries, but there was an association of Individual paternal deprivation measure with one of the anthropometric measure was mid arm circumference. In paternal deprivation index 21.8% of the children's parent were not deprived, 45.8% were somewhat deprived, 22.6% were deprived, 7.3% were very deprived, 2.6 were extremely deprived among school children.

Purpose: to investigate and determine anthropometric indicators (length and body weight, abdominal circumference, skin fold thickness, calculate body mass index and percentage of adipose tissue) of examined patients with metabolic syndrome, evaluate the effectiveness of our comprehensive physical therapy program based on the study of the dynamics of anthropometric indicators women with metabolic syndrome during the rehabilitation process. Material and methods: 28 women with metabolic syndrome were examined, the main group (MG) (n = 14) and the control group (CG) (n = 14), the average age was in MG – 31.49 ± 0.71 years, in the CG – 31.06 ± 0.57 years. Women of the main group studied according to the author’s program of physical therapy, women of the control group - according to the program, used for metabolic syndrome according to the methods of S.M. Popova (2005, 2008), N.A. Beloy (2001). Results: allowed us to analyse the dynamics before the indicators were fully scrutinized by the programs of physical therapy and to separate the results from the main and control groups. Conclusions: the author's program of physical therapy is effective, was carried out in order to normalize body weight and reduce the manifestations of abdominal obesity. Keywords: anthropometry, author’s program, women, physical therapy, metabolic syndrome.

Diastasis recti is a pathology that affects not only the abdominal wall but also the stability of lumbopelvic muscles, consequently altering urinary and digestive functionality. Preaponeurotic endoscopic repair (REPA) is an endoscopic alternative to tummy tuck for the treatment of diastasis. In this study, the outcomes of REPA application by a single surgeon are presented. A total of 172 patients underwent REPA for the treatment of diastasis recti between August 2017 and December 2019. One hundred twenty-four patients were followed for at least one year. Sixty-three patients responded to a survey on satisfaction and quality of life 12 months after surgery. Three (2.4%) recurrences occurred, of which two occurred in the same patient. The main postoperative complications observed were 12 (9.7%) seromas, 3 (2.4%) haematomas, a single wound infection, 3 (2.4%) cases of skin fold formation, and a case of trophic skin lesion that required negative pressure therapy. Quality of life after surgery, as reported by 63 patients who responded to the survey, was satisfactory. REPA is a safe and effective technique for diastasis recti treatment, representing a valid alternative to abdominoplasty. Since there is no need to access the peritoneal cavity and the mesh is onlay, there are no risks of bowel damage or adhesions between the intestine and prosthesis.

Cerebral palsy (CP) causes walking disability in children which could lead to profound changes in body composition. This study assessed relationship between body composition and each of dynamic muscle strength, mobility and energy cost of ambulation (ECA) among children with CP. The cross sectional survey, recruited participants from a secondary and a tertiary hospitals in Kano. Body composition was assessed with BMI for age charts and skin fold calipher. Dynamic muscle strength, balance and ECA were assessed with step-up test, time-up-and-go test and physiological cost index respectively. Data was analysed with Pearson Product Moment Correlation and unpaired t test at alpha level of P0.05). It was concluded that about two-thirds of the children with CP in the study are underweight and having low percent body fat. Body composition may not have significant influence on the muscle strength, stability and the energy expended during walking function. Paediatricians and physiotherapists should encourage caregivers of children with CP to feed them with balanced diet in order to avoid diseases associated with malnutrition.

A system of fifteen variables (7 morphological and 8 variables for assessing postural status) was applied to a sample of 284 male and female students from the first to the third grade of primary school, with the aim of determining the differences between boys and girls. The results showed that there were statistically significant differences between the examined samples in the following morphological variables: in the first class (body weight and skin fold of the triceps), in the second class (body height, body weight, skin fold of the triceps and skin fold of the biceps) and in third grade (body height, skin fold of triceps, skin fold of back, skin fold of biceps, and skin fold of lower leg). Statistically significant differences in the variables for assessing postural status exist in the following variables: in the first grade (head posture, shoulder posture, shoulder posture, chest shape and leg shape), in the second grade (shoulder posture, chest shape, and spinal deviation in frontal plane) and in the third grade (deviation of the spinal column in the frontal plane, holding the anterior abdominal wall and the shape of the legs). Based on the obtained results, it can be concluded that in the younger school-age in morphology there is a significant sexual dimorphism and with it in connection with the change of postural status.

Some of the severe manifestations of Werdnig-Hoffmann disease are the pseudobulbar and bulbar syndromes complicated by the hypotrophy of the various degrees of severity. The clinical case of the nutritional support for the child with grade II hypotrophy that complicated the course of Werdnig–Hoffmann disease in one-year-old child is presented. The purpose of this study is to assess the effect of Clinutren Junior high-calorie formula for children from 1 to 10 years of age on the growth and development of the child diagnosed with type I spinal muscular atrophy. The results were analyzed according to the degree of change in the following anthropometric data: mid-arm circumference, mid-hip circumference, the size of the skin fold in the periumbilical region, as well as laboratory data, as follows: albumin, total protein, lymphocytes.

Introduction: Extracorporeal shock waves (ESWs) have been shown to have a positive effect on skin wound healing; however, little is known on the regeneration of the microcirculation and angiogenesis as well as the different application modes. Methods: A total of 40 BALB/c mice were provided with dorsal skin fold chambers and were divided into 3 therapy groups (n = 30) and one control group (n = 10). The 3 therapy groups were treated with shock waves at different pulse rates (500–1,000 pulses/min) and application frequencies (day 0 and day 6 or day 0 only). Photographic documentation and intravital microscopy were carried out on day 1, 2, 4, and 6 after wounding. Results: Using the newly developed Diver Box, shock waves could be applied in vivo without mechanical tissue damage. Shock wave therapy to skin wounds demonstrated to induce faster wound closure rates in the beginning than controls in groups with higher pulse rates and frequencies of the shock waves. Furthermore, the regeneration of microcirculation and perfusion in the healing skin was significantly improved after the application of, in particular, higher pulse rates as given by increased numbers of perfused capillaries and functional vessel density. The study of inflammation showed, especially in high-pulse ESW groups, higher leukocyte counts, and rolling leukocytes over time until day 6 as a response to the induction of inflammatory reaction after ESW application. Angiogenesis showed a marked increase in positive areas as given by sprouts, coils, and recruitments in all ESW groups, especially between days 4 and 6. Conclusion: The major findings of this trial demonstrate that ESW therapy to skin wounds is effective and safe. This is demonstrated by the initially faster wound closure rate, but later the same wound closure rate in the treatment groups than in controls. Furthermore, during the regeneration of microcirculation and perfusion in the healing skin, a significant improvement was observed after the application of, in particular, higher ESW pulse rates, suggesting an ESW-related increase in nutrient and oxygen supply in the wound tissue.

Introduction: Prematurity is associated with increased cardiometabolic risk later in life. The adipomyokine irisin has been acknowledged as a modulator of energy metabolism and insulin sensitivity. The aim of this study was to investigate circulating levels of irisin and their relation to anthropometric measurements and cardiometabolic phenotype in a population of preterm-born children versus full-term-born peers. Methods: A total of 160 children (87 born preterm aged 8.1–14.8 years and 73 born full-term of similar age and gender distribution) were studied. Arterial blood pressure, anthropometry, body composition assessments with dual energy X-ray absorptiometry, and skinfold measurements were performed. Blood biochemistry and circulating levels of irisin, insulin, cortisol, leptin, and adiponectin were also determined. Results: The preterm group had higher diastolic blood pressure, triceps skinfold, subscapular skinfold (SSSF), and abdominal skinfold measurements and more central adiposity than the full-term group. Irisin was significantly lower (p = 0.002), whereas leptin was higher (p = 0.03) in the preterm than the full-term group. Irisin correlated positively with gestational age (r = 0.19, p = 0.01), birth weight (r = 0.23, p = 0.003), and high-density lipoprotein cholesterol (r = 0.20, p = 0.01) and negatively with SSSF (r = −0.25, p = 0.003) and chronological age (r = −0.21, p = 0.008). Conclusion: Lower levels of irisin and a slightly unhealthy adiposity and cardiometabolic pattern were detected in preterm-born children in comparison to their full-term-born peers. Whether low irisin levels in preadolescents and adolescents born prematurely could be of prognostic value for the development of cardiometabolic sequelae later in life remains to be further studied.

Introduction: Skin fold thickness is a measure of adiposity and is a validated method of assessing malnutrition in older children. The present study was undertaken to see the role of skin fold thickness measurement in neonates as an index of foetal nutritional assessment and to compare between CAN (Clinical Assessment of Nutrition) score and other anthropometric indicators in foetal malnutrition (FM). Methods: A prospective observational study was conducted in postnatal ward of Universal College of Medical Sciences-Teaching Hospital for a duration of six months. Three hundred seventy term newborns were assessed by CAN score and anthropometry recorded. The CAN score was determined and those with scores < 25 was classified as having foetal malnutrition. Skin fold thickness using the Slim Guide skin fold caliper was taken at the triceps, biceps, sub scapular, supra iliac and quadriceps locations for each neonate. Two readings were taken at every site and the mean was recorded. All the skin fold thickness measurements were correlated with the CAN score and statistical comparisons were made. Results: Incidence of FM was 18.38%. The mean (SD) for sum of all skin-fold thickness at all sites for males and females were 4.3 ± 1.61 and 4.18 ± 0.72 mm respectively. All the skin-fold thickness measurements correlated significantly with the CAN score, but the sum of the five had the best correlation. The mean (SD) of anthropometric data of babies and sum of all comparing foetal malnutrition versus without foetal malnutrition using nutritional status CAN score was statistically significant (p-value < 0.001). Conclusions: The sum of all five skin-fold measurements might be a useful screening tool for FM in view of its objectivity, convenience and simplicity, but it is not sufficiently sensitive or specific to replace the CAN score in the identification of FM in neonates.

The objective of the present study was to evaluate clinico-biochemical changes occurred in bacterial diarrhea in Egyptian Buffalo calves less than three months old. The study was carried out on 50 buffalo calves in El-Galaa Military farm that located in Ismailia Governorate, 40 diarrheic calves aged 55-75 days with an average body weight (35±2.5) kg were detected and 10 apparently healthy calves were kept as a control group to investigate the clinico-biochemical profiles. E. coli mixed or co-infection of Acinetobacterbaumannii/Iwoffiiss species with Klebsiella and pseudomonas species were isolated from the diarrheic calves. Diarrheic calves show signs of anorexia, weakness, dullness, staggering movement, weight loss, pale mucous membranes with sunken eyes and dehydration. Analysis of clinical and biochemical profile of the diarrheic calves revealed significant increase in body temperature, respiratory rate, skin fold test, serum potassium, chloride, urea, creatinine, ALT, AST, GGT, triacylglycerols, cortisol, CRP and CPK withsignificant decrease in pulse rate, serum sodium, glucose and total protein concentrations.It could be concluded that, bacterial diarrhea has a severe negative impact on the clinical and biochemical profile of the affected buffalo calves.

Resumen Introduccion La asociacion entre la presencia de sobrepeso/obesidad y el estado clinico de la artritis reumatoide (AR) es un tema aun no resuelto. Objetivo Evaluar la asociacion entre el tipo de composicion corporal y el estado clinico en pacientes con AR. Metodos Estudio prospectivo, comparativo y transversal que incluyo a 123 pacientes (98,4% mujeres, 86,3% FR+, 9,3±8,7 anos de duracion) con AR (criterios ACR/EULAR 2010) en quienes se determino actividad inflamatoria (DAS 28), estado funcional (HAQ-Di) y tipo de tratamiento; ademas, el tipo de composicion corporal evaluada por IMC, circunferencias de cintura, cadera y brazo medio, indice cintura/cadera, plicometria y bioimpedancia electrica. Resultados Las prevalencias de sobrepeso y obesidad (IMC-OMS) fueron del 30,9% y del 45,5%. Cuando se reclasificaron mediante los puntos de corte de Stavropoulos-Kalinoglou, las prevalencias aumentaron a 31,7 y 58,5%, respectivamente. Con este criterio, los pacientes con sobrepeso/obesidad tuvieron mas articulaciones inflamadas que los pacientes con composicion corporal subnormal/normal (3,8±3,3 vs. 1,9±2,5; p=0,02). El conteo de articulaciones inflamadas mostro correlacion positiva significativa con 6 de 11 metodos antropometricos: IMC, circunferencia de brazo y cadera, pliegue tricipital y porcentaje de grasa corporal (determinado por bioimpedancia electrica y plicometria). Conclusiones El sobrepeso y la obesidad se asociaron a mayor actividad inflamatoria caracterizada por mayor cantidad de articulaciones inflamadas. Encontramos correlacion positiva significativa entre el numero de articulaciones inflamadas y la mayoria de los indicadores de masa grasa corporal estudiados. La evaluacion y optimizacion de la composicion corporal podria llegar a ser una parte importante para el abordaje clinico de pacientes con AR. Introduction The effect of overweight/obesity on clinical status in rheumatoid arthritis (RA) is still a controversial topic. To assess the association between body composition and clinical status in RA patients. Methods A prospective, comparative, cross-sectional study was performed on 123 (98.4% women, 86.3% FR+, 9.3±8.7 duration years) RA patients diagnosed according to ACR/EULAR 2010 criteria who were assessed for inflammatory activity (DAS 28), functional status (HAQ-Di), and type of treatment. Body composition was evaluated by BMI, waist, hip, and middle arm girths, waist/hip ratio, skin fold measurements, and bioelectrical impedance analysis. Results The prevalence of overweight and obesity (BMI-WHO cut-off points) was 30.9% and 45.5% respectively. Using Stavropoulos-Kalinoglou cut-off points, each corresponding prevalence increased to 31.7% and 58.5%, respectively. Pooled patients in the overweight/obesity classification (Stavropoulos-Kalinoglou classification) exhibited a significantly higher number of swollen joints as compared to subnormal/normal body composition subjects (3.8±3.3 vs. 1.9±2.5; p=.02). Swollen joint count showed significant positive correlation with 6 out of 11 body composition parameters: BMI; arm and hip girths, triceps skin fold, body fat average determined by bioelectrical impedance analysis, and skin fold measurements. Conclusions Prevalence of obesity in RA varies according to BMI cut-off points. Overweight and obesity were associated with higher inflammatory activity characterized by a higher count of tender and swollen joints. A positive correlation was found between swollen joint amount and the majority of the body fat mass indicators assessed. Body composition assessment/improvement should be an important part of the routine care of RA patients.

Background and Study Aim. ln this academic research, it was aimed to compare the physical activity and skinfold thickness of the students living in the city center and rural areas. Material and Methods. 89 students attending the 6th grade level, whose total age is 12 years old, residing in the city center and rural areas of Çanakkale participated in the study. Students were examined with SenseWear armband bmi, total energy consumption, daily step count, met, active energy consumption, physical activity time, reach time and sleep times. Body mass index was determined with Holtain Skinfold Caliper. For the analysis of the dataset, the Independent Sample t test was utilized to examine the difference between the students' physical activity levels and skin fold thickness. Then, the relevance between physical activity level and skinfold thickness was examined for pearson correlation. Significance value p

Penelitian ini bertujuan untuk mengungkap 1) Pengaruh latihan senam aerobik terhadap penurunan berat badan 2) Pengaruh latihan senam aerobik terhadap persentase lemak tubuh, dan 3) Pengaruh latihan senam aerobik terhadap peningkatan massa otot. Penelitian mengunakan eksperimen semu (quasi-exsperiment). Populasi adalah semua anggota senam fit club simpang D Kabupaten Rokan Hulu, dengan sampel berjumlah 10 orang. Teknik pengambilan sampel dilakukan dengan total sampling dengan jumlah 10 orang. Instrumen penelitian untuk memperoleh data adalah: (1) Timbangan badan digital innerscan Tanita BC-541 body composition untuk mengukur berat badan, (2) Skin fold caliper untuk mengukur persentase lemak tubuh dan (3) Timbangan badan digital innerscan Tanita BC-541 body composition untuk mengukur massa otot. Teknik analisa data yang digunakan adalah uji t. Hasil dan analisa data menunjukkan bahwa: (1) Latihan senam aerobik memberikan pengaruh yang signifikan terhadap penurunan berat badan thitung 2,186 > ttabel 1.782. Nilai rata-rata pretest 66,86 kg dan posttest 66,12 kg. Terdapat penurunan 0,74 kg. (2) Latihan senam aerobik memberikan pengaruh yang signifikan terhadap penurunan persentase lemak tubuh thitung 3,285 > ttabel 1.782. Nilai rata-rata pretest 40.45 % dan posttest 37,18 %, Terdapat penurunan 3,27 %.(3) Latihan senam aerobik memberikan pengaruh yang signifikan terhadap massa otot thitung 1,835 > ttabel 1.782. Nilai rata-rata pretest 37,72 dan posttest 37,63,Terdapat penurunan 0,09 %.

Malnutrition is very common in patients on hemodialysis. Assessing the malnutrition status of haemodialysis patients is important for treatment and better health of the patients. Anthropometric measurements, both parts of anthropometry are used to assess the nutritional status. Objective: To assess the nutritional status of hemodialysis patients. Methods: A cross-sectional study was conducted at Bahria International Hospitals, Lahore and completed within 9 months using the convenient sampling technique. The data were collected through pretested questionnaire from 385 dialysis patients. Data were analyzed in the form of mean, frequencies, percentage and standard deviation with the help of SPSS version 22.0. Results: 50.5 % of the patients had normal body mass index (BMI) and 9.2% had BMI less than 18 which were underweight according to the WHO criteria. The mean and standard deviation of mid upper arm circumference (MUAC), mid arm muscle circumference(MAMC) and skin fold thickness (SFT) were 13.22±6.16, 20.40±4.67 and 1.67±0.54. Biochemical data showed mean and standard deviation of urea, creatinine and albumin were 104.37±38.63, 3.46±7.2716 and 3.46±0.72. Dietary intake included average energy intake i.e. 612.16±243.95, protein intake i.e. 30.61±10.98, fluid i.e. 738.11±223.06, sodium intake i.e. 949.60±578.96 and potassium intake i.e. 918.77±359.52. Conclusions: Most of the patients on haemodialysis were malnourished. These patients need dietary advice, care and monthly routine check-up of biochemical and anthropometric data to prevent from further complications.

During the preclinical studies of new drugs, the study of the degree of manifestation of their irritant and allergenic effects affects subsequent clinical studies, for example the routes of administration, the need to add excipients to reduce irritation. The article presents the results of studies of the irritant effects and allergenic properties of the Iron in rare unconventional valence – IV. The irritant effect of the Iron(IV) clathrochelate complexes on the skin was studied comprehensively. 20 rabbits were divided into 4 groups (control and three experimental), 5 animals each. The ointment on the vaseline and aqueous solution of the Iron(IV) clathrochelate complexes was applied to the skin of rabbits of the experimental groups. Also this solution was introduced subcutaneously. The investigated dosage forms were used at a dose of 1 ml/kg body weight (based on the active ingredient 500 mg/kg body weight of the laboratory animal). The results of the studies showed that of the Iron(IV) clathrochelate complexes has no irritant properties when used externally and is characterized by a lack of local reaction by subcutaneous injection. Determination of allergenic properties was performed by detecting itching and swelling in the guinea pigs in animals which were sensitized with this substance. In addition, in order to assess the severity of the inflammatory reaction, the skin temperature was determined before the experiment and on the 20th day of the experiment, and the skin fold thickness was measured using a caliper. The results of the studies showed that there is no allergic action of the Iron(IV) clathrochelate complexes. The results of the ophthalmic test on laboratory animals confirmed the data obtained.Therefore, comprehensive studies of the irritant and allergenic effects of the Iron(IV) clathrochelate complexes were performed for the first time. The Iron(IV) clathrochelate complexes in the form of ointment and solution does not irritate the skin and mucous membranes and has no allergenic properties to the body of the laboratory animals.

Objective:Waist-to-height ratio has been shown to be an important indicator of cardiometabolic risk. There are few studies evaluating this measure against existing measures of adiposity and cardiometabolic markers in early childhood. The objectives were: (i) to determine in young children the ability of waist-to-height ratio, BMI z-score, weight for length, and sum of skin fold thickness to predict cardiometabolic risk and (ii) to examine this association at ages 1, 3 and 5 years.Design:Prospective cohort study.Setting:A university hospital in Toronto, Ontario.Participants:Infants at 1 (n 406), 3 (n 112) and 5 years of age (n 94) born to mothers with and without gestational diabetes mellitus.Results:Weight for length and BMI z-score demonstrated the strongest correlations with biochemical measures compared to waist-to-height ratio, including leptin (at 5 years, weight for length z-score: ρ = 0·65, P < 0·001; BMI z-score: ρ = 0·67, P < 0·001) and measures of insulin resistance (at 3 years, weight for length z-score: ρ = 0·25, P = 0·02; BMI z-score: ρ = 0·24, P = 0·02). The magnitude of associations between anthropometric measures and biochemical measures strengthened over time. Weight for length and BMI z-scores were moderately correlated with overall measures of fat mass as measured by dual-energy X-ray absorptiometry (ρ = 0·65, P = 0·00; ρ = 0·61, P = 0·01).Conclusions:Waist-to-height ratio was not superior to existing measures in predicting cardiometabolic risk in young children. BMI z-score is a preferred measure of adiposity between birth and 5 years of age.

Background Ayurveda, the Indian system of medicine offers many herbs and formulations for management of obesity. Baidyanath Bhawan Pvt. Ltd has designed a formulation, HFO-02, based on Ayurvedic literature. Objective To evaluate the efficacy of Herbal Formulation for Obesity (HFO-02) in overweight individuals. Materials & methods With approval from the Institutional Ethics Committee, a proof of concept study was carried out in overweight individuals (Body Mass Index, BMI ≥25.0 and ≤ 30.0 kg/m2), devoid of any endocrinological disorders. Tablet HFO-02 (500 mg) was administered to these individuals twice daily for 90 days, during which they were called at study site fortnightly. After stopping the treatment, they were further followed up for 30 days off-medication and the last follow up was scheduled on day 120. Anthropometric parameters were assessed at every visit, while biochemical parameters viz. lipid profile, blood sugar & insulin levels (both fasting and post prandial), C- reactive protein and adipocytokines (leptin & adiponectin) were estimated monthly. Results Of the 18 participants recruited in the study; 14 completed the study. HFO-02 did not show reduction in weight, however a significant decrease in the body circumference and skin fold was demonstrated. This decrease was maintained till day 120. The levels of all biochemical parameters were maintained and no adverse events were reported throughout the study. Conclusion Tablet HFO-02 reduced body circumferences and skinfold thickness indicating its potential for obesity management. Clinical trial registration number CTRI/2016/07/007067.

An open label, randomized, comparative, interventional pilot study was done to assess the effect of Lekhana Basti (medicated enema) and Rechana Nasya Karma (Errhine therapy) in the management of Sthoulya with special reference to obesity. In the study 30 clinically diagnosed patient of either sex were randomly divided into two groups. In Basti group, Lekhana Basti in Karma Basti manner was given for 30 days. Anuvasana Basti (enema with Triphaladi Taila) in the dose of 120 mL and Asthapana Basti (enema with Triphaladi decoction etc.) in the dose of approximately 960 mL was given. In Nasya group, Rechana nasya on alternate days was given with Triphaladi (oil) in the dose of 0.5 mL per nostril for total 28 days. The patients were assessed on objective criteria such as such as weight, chest circumference, mid-arm circumference, mid-thigh circumference, triceps skin fold thickness, sub-scapular skin fold thickness, abdominal skin fold thickness, waist-hip ratio and lipid profile. It was observed that Basti group was a better intervention in providing relief, however there intergroup standard deviation was low on most of the variable expect the lipid profile. The results suggest that the Nasya Karma may be developed as a better practical approach in obesity management.

Classic Ehlers-Danlos syndrome (EDS) is a connective tissue disorder characterized by laxity. The skin, as one of the organs involved, shows hyperextensibility, which makes it prone to trauma. In this context, it would seem logical for cutaneous synovial metaplasia, which is considered a form of repair, to be commonly found in cases of EDS. However, there are only two previously published cases of synovial metaplasia in EDS. We present a third case in a 56-year-old woman with painful redundant skin in both elbows and knees for whom a skin fold of the left elbow was removed to relieve her symptoms. The biopsy showed preservation of the elastic and collagen fibers. The main alteration was the evidence of dermal cystic spaces lined by fibrinoid rests with focal pseudopapillary projections. However, in some zones the cellular lining was preserved, and it was composed of vimentin-positive, fibroblast-like flat, elongated cells, as well as CD68-positive macrophages. No birefringent particles were found in an examination under polarized light.

The purpose of the study was to observe the Physical fitness and body composition of national level female football players. 22National level 15 to 18 years female football players were selected as subjects of this study. To conduct the study AAHPERD youth physical fitness test battery (i.e. 50 yard dash, sit up, flex arm hang, standing broad jump, shuttle run and 600 yard run/walk )and skin fold method of Jackson & Pollock for body composition were taken as criterion measure. After collecting the data descriptive statistics and correlation analysis were adopting and the following conclusions were drawn – 1. The female National level football players of Purba Medinipur district were found having more lean body mass. 2. % of fat was found less in female National level football players. 3. No significant relation was found between physical fitness and Body Composition.