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INTRODUCTION: Ischemic heart disease (IHD) remains a leading cause of death and disability worldwide. This study evaluates the trends in IHD burden attributable to smoking, utilizing Global Burden of Disease Study 2021 (GBD 2021) data, across 204 countries and territories from 1990 to 2021. By examining age-standardized death rates (ASDR) and disability-adjusted life years (ASRDALYs), the study provides insights into the spatiotemporal variations associated with smokingattributable IHD in different sociodemographic regions. METHODS: Data on smoking-attributable IHD mortality and DALYs were obtained from the GBD 2021 database. This secondary analysis examined ASDR and ASRDALYs for IHD as primary outcomes, with active smoking as the primary exposure. Temporal trends were analyzed using estimated annual percentage changes (EAPCs). The burden was stratified by age, sex, and sociodemographic index (SDI) to identify disparities across regions. RESULTS: Over the last three decades, global ASDR and ASRDALYs for smokingrelated IHD have generally declined. High-SDI regions had the largest reductions, with EAPCs of -4.31 (95% CI: -5.73 – -2.87) and -4.02 (95% CI: -5.40 – -2.62), respectively. In contrast, low-SDI regions experienced slower declines, with EAPCs of -0.54 (95% CI: -1.41–0.33) and -0.80 (95% CI: -1.52 – -0.08), respectively. Older age groups and males consistently had a higher burden across all regions. Global death rates for populations aged 15–49, 50–74, and ≥75 years were 4.31, 46.57, and 142.52 per 100000, respectively. The global ASDR for males (30.24) was 8.54 times higher than that for females (3.54). Regional disparities were most pronounced in low- and middle-income areas, particularly in Eastern Europe and Central Asia, where smoking related IHD burden remains high. CONCLUSIONS: While global reductions in smoking-related IHD burden are encouraging, sustained disparities remain, particularly in low-SDI regions. Males and older populations continue to have a disproportionately higher burden, emphasizing the need for targeted interventions and sustained efforts to address these inequities. [ABSTRACT FROM AUTHOR]

Recent challenges and opportunities necessitate a reexamination of the spatial dynamics of US poverty. In our study, we employed the emerging hot spot analysis to discern spatial and temporal variations in US poverty from 2006 to 2021, across various spatial scales. The primary innovation of this analysis is its capacity to monitor shifts in spatial patterns of poverty over time, providing a dynamic perspective essential for comprehending and addressing non-static processes. We discovered that the majority of US counties exhibit consistent poverty trends, characterized by either persistent or intensifying hot spots (clusters of high poverty) or cold spots (clusters of low poverty), with only a minority experiencing recent changes in poverty trajectories. The choice of spatial scale significantly influences these trends. Our intersectional analysis of poverty with age and race demonstrated that the categories of children and adults have a markedly higher number of counties with persistent and intensifying hot spots compared to the elderly category. Nonetheless, the elderly category has a greater number of new emerging hot spots. Furthermore, our exploration of the interaction between race and poverty dynamics showed that the spatial patterns of emerging poverty hot spots vary among racial groups and do not align with their population distributions. These findings underscore the need for a nuanced and adaptive approach to policy development and implementation. [ABSTRACT FROM AUTHOR]

Abstract Background China’s family planning policies have experienced stages of one-child policy, partial two-child policy, and universal two-child policy. However, the impact of these policy shifts on the spatial accessibility to maternal and child health (MCH) services for women and children remains uncertain. This study aimed to evaluate the spatiotemporal trends and geographic disparities in spatial accessibility to MCH services in the context of two-child polices. Methods This study was conducted in Nanning prefecture, China, from 2013 to 2019. Data on the transportation networks, MCH institutes, the annual number of newborns, and the annual number of pregnant women in Nanning prefecture were collected. Gaussian two-step floating catchment area (Ga2SFCA) method was employed to measure the spatial accessibility to MCH services at county, township, and village levels. Temporal trends in spatial accessibility were analyzed using Joinpoint regression analysis. Geographic disparities in spatial accessibility were identified using geographic information system (GIS) mapping techniques. Results Overall, the spatial accessibility to MCH services showed an upward trend from 2013 to 2019 at county, town, and village levels, with the average annual percent change (AAPC) being 5.04, 4.73, and 5.39, respectively. Specifically, the spatial accessibility experienced a slight downward trend during the period of partial two-child policy for both parents only children (i.e., 2013–2014), a slight upward trend during the period of partial two-child policy for either parent only child (i.e., 2014–2016) and the early stages of universal two-child policy (i.e., 2016–2018), and a large upward trend in the later stages of universal two-child policy (i.e., 2018–2019). Spatial accessibility to MCH services gradually decreased from central urban areas to surrounding rural areas. Regions with low spatial accessibility were predominantly located in remote rural areas. Conclusion With the gradual opening of the two-child policies, the spatial accessibility to MCH services for women and children has generally improved. However, significant geographic disparities have persisted throughout the stages of the two-child policies. Comprehensive measures should be considered to improve equity in MCH services for women and children.

Background: China's family planning policies have experienced stages of one-child policy, partial two-child policy, and universal two-child policy. However, the impact of these policy shifts on the spatial accessibility to maternal and child health (MCH) services for women and children remains uncertain. This study aimed to evaluate the spatiotemporal trends and geographic disparities in spatial accessibility to MCH services in the context of two-child polices. Methods: This study was conducted in Nanning prefecture, China, from 2013 to 2019. Data on the transportation networks, MCH institutes, the annual number of newborns, and the annual number of pregnant women in Nanning prefecture were collected. Gaussian two-step floating catchment area (Ga2SFCA) method was employed to measure the spatial accessibility to MCH services at county, township, and village levels. Temporal trends in spatial accessibility were analyzed using Joinpoint regression analysis. Geographic disparities in spatial accessibility were identified using geographic information system (GIS) mapping techniques. Results: Overall, the spatial accessibility to MCH services showed an upward trend from 2013 to 2019 at county, town, and village levels, with the average annual percent change (AAPC) being 5.04, 4.73, and 5.39, respectively. Specifically, the spatial accessibility experienced a slight downward trend during the period of partial two-child policy for both parents only children (i.e., 2013–2014), a slight upward trend during the period of partial two-child policy for either parent only child (i.e., 2014–2016) and the early stages of universal two-child policy (i.e., 2016–2018), and a large upward trend in the later stages of universal two-child policy (i.e., 2018–2019). Spatial accessibility to MCH services gradually decreased from central urban areas to surrounding rural areas. Regions with low spatial accessibility were predominantly located in remote rural areas. Conclusion: With the gradual opening of the two-child policies, the spatial accessibility to MCH services for women and children has generally improved. However, significant geographic disparities have persisted throughout the stages of the two-child policies. Comprehensive measures should be considered to improve equity in MCH services for women and children. [ABSTRACT FROM AUTHOR]

Understanding the spatiotemporal patterns and variations in vapor pressure deficit (VPD) is essential for effective water resource management in the face of climate change. VPD serves as a fundamental indicator of atmospheric dryness, directly impacting plant evapotranspiration rates, thereby affecting overall ecosystem functioning. In this study, VPD changes in five subregions and four ecological types of land in Yunnan from 1980 to 2021 were investigated using data from 108 meteorological stations. We found increasing trends in annual VPD that were larger during warmer spring and summer seasons. Among the subregions, the highland subtropical southern broadleaved evergreen forest ecoregion exhibited the largest drying trend (0.04 kPa / decade), while the subtropical (eastern) humid broadleaved evergreen forest ecoregion had the smallest drying trend (0.01 kPa / decade). Among the ecological barriers, the dry-hot valleys had significantly higher increases in VPD compared to other Yunnan regions. Increases in VPD from 1990s to 2000s in several regions of Yunnan exceeded atmospheric drying trends reported elsewhere. Additionally, we documented smaller VPD declines at higher elevations. Across different ecological land types, Shrubland exhibited the largest VPD trend (0.07 kPa / decade), while Forest displayed the smallest (0.03 kPa / decade). Decreased relative humidity through time explained 65% of the increase in VPD in Yunnan, while increasing temperatures accounted for 25%. These findings provide valuable insights into climatic dynamics of Yunnan, with implications for ecological, hydrological, and atmospheric studies. [ABSTRACT FROM AUTHOR]

The Horn of Africa has sensitive, arid ecosystems, with its vegetation commonly distressed by factors such as climate change, population increase, unstable water resources, and rarely enforced land use management practices. These factors make countries such as Djibouti highly variable locations for the growth of vegetation and agricultural products, and these countries are becoming more vulnerable to food insecurity as the climate warms. The rapid growth of satellite and digital image processing technology over the last five decades has improved our ability to track long-term agricultural and vegetation changes. Data cubes are a newer approach to managing satellite imagery and studying temporal patterns. Here, we use the cloud-based Digital Earth Africa, Open Data Cube to analyze 30 years of Landsat imagery and orthomosaics. We analyze long-term trends in vegetation dynamics by comparing annual fractional cover metrics (photosynthetic vegetation, non-photosynthetic vegetation, and bare ground) to the Normalized Difference Vegetation Index. Investigating Djibouti-wide and regional vegetation trends, we provide a comparison of trends between districts and highlight a primary agricultural region in the southeast as a detailed example of vegetation change. The results of the Sen's slope and Mann–Kendall regression analyses of the data cube suggest a significant decline in vegetation (p = 0.00002), equating to a loss of ~0.09 km2 of arable land per year (roughly 2.7 km2 over the 30-year period). Overall, decreases in photosynthetic vegetation and increases in both non-photosynthetic vegetation and bare soil areas indicate that the region is becoming more arid and that land cover is responding to this trend. [ABSTRACT FROM AUTHOR]

The zebra mussel Dreissena polymorpha is one of the most successful, notorious, and detrimental aquatic invasive non‐native species worldwide, having invaded Europe and North America while causing substantial ecological and socio‐economic impacts. Here, we investigated the spatiotemporal trends in this species' invasion success using 178 macroinvertebrate abundance time series, containing 1451 records of D. polymorpha collected across nine European countries between 1972–2019. Using these raw (absolute) abundance data, we examined trends and drivers of occurrences and relative abundances of D. polymorpha within invaded communities. Meta‐regression models revealed non‐significant trends both at the European level and for the majority of the invaded countries, except for France (significant decreasing trend) and Hungary (marginally positive trend). At the European level, the number of D. polymorpha occurrences over time followed a flat‐top bell‐shaped distribution, with a steep increase between 1973–1989 followed by a plateau phase prior to significantly declining post‐1998. Using a series of climatic and hydromorphological site‐specific characteristics of invaded and uninvaded sites from two periods (1998–2002; 2011–2015), we found that native richness, non‐native abundance, distance to the next barrier, and elevation were associated with the occurrence of D. polymorpha. We also found that higher native richness and lower latitude were related to lower relative abundances. Using Cohen's D as a measure of D. polymorpha impact, we found that biodiversity within the invaded sites was initially higher than in uninvaded ones, but then declined, suggesting differences in biodiversity trends across invaded and uninvaded sites. While our results emphasise the high invasion success of D. polymorpha, increasing stressors within the context of global change – particularly ongoing climate change – are likely to enhance invasion rates and the impact of D. polymorpha in the near future, exacerbated by the lack of timely and effective management actions. [ABSTRACT FROM AUTHOR]

The epidemiological trends of cardiovascular disease (CVD) burden attributed to low physical activity (LPA) across various regions and countries are poorly understood. Hence, we assessed the global, regional, and national spatiotemporal trends of LPA-related CVD from 1990 to 2019. We conducted a secondary analysis of the Global Burden of Disease Study 2019. The data on LPA-related CVD were examined with regard to sex, age, year, and Socio-Demographic Index (SDI). We assessed the temporal changes in age-standardized mortality rate (ASMR) and age-standardized death rate (ASDR) using the estimated annual percentage change (EAPC) over a 30-year period. There were a staggering 0.64 million deaths and 9.99 million disability-adjusted life-years globally attributed to LPA-related CVD in 2019. The majority of the LPA-related CVD burden was observed in the population aged ≥80 years. It also indicated a high disease burden of LPA-related CVD in Central Asia, Arabian Peninsula, and North Africa. Although there has been a decline in ASMR and ASDR associated with LPA-related CVD on a global scale, the countries experiencing the most substantial increase in LPA-related CVD burden are Uzbekistan, Tajikistan, and Azerbaijan. The ASMR and ASDR remained stable in regions with low, low-middle, and middle SDI levels. The EAPCs of ASMR and ASDR were negatively linked with SDI in 2019. From 1990 to 2019, LPA led to a significant and escalating burden of CVD in certain regions, namely, Uzbekistan, Tajikistan, and Azerbaijan. It is imperative for governments and policymakers to implement regulatory measures and strategic interventions aimed at mitigating this burden. [ABSTRACT FROM AUTHOR]

Physical and climatic variables such as Tree Canopy coverage, Normalized Difference Vegetation Index (NDVI), Distance to Roads, Distance to the Coast, Impervious Surface, and Precipitation can affect land surface temperature (LST). This paper examines the relationships using linear regression models and explores LST trends in the Miami Statistical Area (MSA) between 2002 and 2021. This study evaluates the effect of dry and wet seasons as well as day and night data on LST. A multiscale investigation is used to examine LST trends at the MSA scale, the individual county level, and at the pixel level to provide a detailed local perspective. The multiscale results are needed to understand spatiotemporal LST distributions to plan mitigation measures such as planting trees or greenery to regulate temperature and reduce the impacts of surface urban heat islands. The results indicate that LST values are rising in the MSA with a positive trend throughout the 20-year study period. The rate of change (RoC) for the wet season is smaller than for the dry season. The pixel-level analysis suggests that the RoC is primarily in rural areas and less apparent in urban areas. New development in rural areas may trigger increased RoC. This RoC relates to LST in the MSA and is different from global or regional RoC using air temperature. Results also suggest that climatic explanatory variables have different impacts during the night than they do in the daytime. For instance, the Tree Canopy variable has a positive coefficient, while during the day, the Tree Canopy variable has a negative relationship with LST. The Distance to the Coast variable changes from day to night as well. The increased granularity achieved with the multiscale analysis provides critical information needed to improve the effectiveness of potential mitigation efforts. [ABSTRACT FROM AUTHOR]

Physical and climatic variables such as Tree Canopy coverage, Normalized Difference Vegetation Index (NDVI), Distance to Roads, Distance to the Coast, Impervious Surface, and Precipitation can affect land surface temperature (LST). This paper examines the relationships using linear regression models and explores LST trends in the Miami Statistical Area (MSA) between 2002 and 2021. This study evaluates the effect of dry and wet seasons as well as day and night data on LST. A multiscale investigation is used to examine LST trends at the MSA scale, the individual county level, and at the pixel level to provide a detailed local perspective. The multiscale results are needed to understand spatiotemporal LST distributions to plan mitigation measures such as planting trees or greenery to regulate temperature and reduce the impacts of surface urban heat islands. The results indicate that LST values are rising in the MSA with a positive trend throughout the 20-year study period. The rate of change (RoC) for the wet season is smaller than for the dry season. The pixel-level analysis suggests that the RoC is primarily in rural areas and less apparent in urban areas. New development in rural areas may trigger increased RoC. This RoC relates to LST in the MSA and is different from global or regional RoC using air temperature. Results also suggest that climatic explanatory variables have different impacts during the night than they do in the daytime. For instance, the Tree Canopy variable has a positive coefficient, while during the day, the Tree Canopy variable has a negative relationship with LST. The Distance to the Coast variable changes from day to night as well. The increased granularity achieved with the multiscale analysis provides critical information needed to improve the effectiveness of potential mitigation efforts.

Abstract Objectives To examine the spatiotemporal trends in pancreatic cancer (PC) disability-adjusted life years (DALYs) and mortality attributable to high body-mass index (BMI) by age, gender, and countries from 1990 to 2019. Methods Data were extracted from the Global Burden of Disease Study 2019 results. We presented the annual number of PC DALYs and mortality, and corresponding age-standardized rates (ASDR and ASMR), which were further stratified by age, gender, and countries. The estimated annual percentage change (EAPC) was computed to assess the longitudinal trends in ASRs. Results In 2019, 0.7 million DALYs and 31.9 thousand deaths worldwide were caused by PC attributable to high BMI, with the largest amount reported in high-income North America, Western Europe, and East Asia. The corresponding ASDR and ASMR were highest in females and in high SDI regions, while quite varied across countries. The global EAPC in ASDR and ASMR was 1.45 (95% uncertainty interval [UI]: 1.40, 1.50) and 1.44 (95% UI: 1.39, 1.49), respectively. Almost all involved countries demonstrated significant uptrends in ASRs from 1990 to 2019. Conclusions More productive efforts to reduce the impact of modifiable risk factors, such as overweight, should be undertaken, and thus effectively curb the rise of PC burden.

Objective: To estimate the pooled prevalence, as well as the spatial and temporal distribution, of urolithiasis among subjects in China. Materials and Methods: We conducted a comprehensive search of both Chinese and English databases to retrieve literature pertaining to the prevalence of urolithiasis in the indigenous Chinese population. A random‐effects meta‐analysis model was employed to calculate the pooled prevalence of urolithiasis. Subgroup analyses were conducted based on factors such as time, region, gender, and sample size. Prevalence and spatial distribution maps were created based on provinces and latitude/longitude coordinates. Results: A total of 46 studies conducted in 22 provinces across China were included in this meta‐analysis and the pooled prevalence of urolithiasis, kidney stones, ureteric calculi, urethral and bladder stones were 8.1% (95% confidence interval [CI] 5.6–11.1%), 7.8% (95% CI 5.8–10.0%), 3.2% (95% CI 0.6–5.7%), 0.5% (95% CI 0.1–0.9%). Most of the urolithiasis prevalence screening in China was concentrated between 100° E and 120° E, with higher rates observed in low latitude areas. Subgroup analysis of kidney stones revealed that Guangdong (12.7%) and Guangxi (10.3%) had the highest prevalence, with the eastern developed area exhibiting higher rates compared to the west. The prevalence in males was higher than in females (odds ratio 1.67, 95% CI 1.46–1.92), although the gender gap has significantly reduced since 2006. Moreover, a greater sample size is associated with a decreased prevalence of urolithiasis. Conclusions: The prevalence of urolithiasis is increasing in China, and there are noteworthy regional or provincial disparities in occurrence. It is worth noting that the current number of screening studies in some areas is insufficient. Additional investigations with appropriate sample sizes should be supplemented in time. [ABSTRACT FROM AUTHOR]

The results reveal statistically significant trends with distinct slopes in distinct quantiles for each station and season so that the changes in the trend of high values (quantile 0.9) of evaporation were more than low values (quantile 0.1). In the spring, medium and high evaporation rates increased in the northern regions of the province (the highest trend slope, 0.15 mm/decade in the northeast), while they fell (with a slope of −0.15 mm/decade) in the southern regions. But the high values of evaporation in summer have increased in most of the stations (the highest trend slope, 0.15 mm/decade). In contrast, high levels of evaporation in autumn and winter grew at a rapid rate in the eastern part of the province (the highest slope according to season, 0.15 and 0.2 mm/decade), but they declined in the western half (the highest slope, −0.1 and −0.15 mm/decade, respectively). In general, there was a significant decreasing trend for evaporation, mostly in the western half, but there was an increasing trend, mostly in the eastern half of the province. Significant increases in daily evaporation, particularly during the dry season, will diminish water supplies, destabilize the agricultural sector, and eventually desertify the area. HIGHLIGHTS The trend of evaporation pan was investigated by the quantile regression method.; The amount of change in different quantiles of evaporation pan was estimated.; The high values of evaporation increased in different seasons.; The slope of the trend was different for different amounts of evaporation.;

The intensification of global warming leads to the increased frequency of extreme temperature events. Many studies have reported on numerous regions facing extreme hot and cold temperatures to some degree. In this study, the daily maximum, minimum and mean near‐surface air temperatures were estimated to explore the detailed spatial trends of extreme temperature events along the Qinghai‐Tibet Plateau Transportation Corridor (QTPTC). Sixteen extreme temperature indices were used to represent extreme temperature events, and the Mann‐Kendall trend test and Sen's slope estimation method were employed to explore the spatiotemporal trends of extreme temperatures along the QTPTC during 1981–2019. The possible factors that affect the trends of extreme temperature events were also discussed, indicating that: (a) There was an exacerbation of extreme hot events, while the prevalence of extreme cold events weakened along the QTPTC. This was in accordance with the trend of global warming. (b) The trends of extreme temperature indices based on daily minimum temperature were stronger than those based on daily maximum temperature in most areas, except for the eastern region. Furthermore, as altitude increased, the amplitude of warming intensified. (c) Unlike the trend in most areas, the intensified warming trend occurred in the low‐altitude areas in the eastern region where there are more human activities and rapid urbanization, and the daily maximum temperature trend was more severe there. The results can provide references for policymakers to formulate corresponding adaptation strategies, addressing the impacts of extreme temperature events on transportation facilities with significant elevation differences. Plain Language Summary: With the intensification of global warming, extreme hot events occur more frequently. The frequent extreme temperature events may induce many natural disasters along the QTPTC. Many studies represent extreme temperature events by calculating the extreme temperature indices based on meteorological stations in situ. Due to the sparse meteorological stations in this region, we have produced a gridded air temperature product for nearly 40 years and conducted extreme indices calculations and trend analysis to obtain the spatiotemporal trends of extreme temperature events. The results indicate the intensification of extreme hot events and the reduction of extreme cold events in the region, and this was in accordance with the trend of global warming. As the altitude increased, the amplitude of warming intensified except the low‐altitude areas. The low‐altitude areas in the east did not follow this pattern, possibly due to more human activities here. It could provide comprehensive references for infrastructure construction, railway operation and the safety of residents along the QTPTC, as well as other transportation projects in mountainous areas. Key Points: Spatial trends of extreme temperature events were detected using the gridded temperature productExtreme hot events generally increase with altitudeThe intensification of extreme hot events in the low‐altitude areas is likely due to human activities and urbanization [ABSTRACT FROM AUTHOR]

The aim of this study was to estimate the burden of rheumatic heart disease (RHD) and its trends in different countries, regions, genders and age groups globally. Data were obtained from the Global Burden of Disease 2019 study. Age-standardized rates (ASRs) and the estimated annual percentage changes (EAPCs) in the ASRs were used to describe the burden of disease and its trends. Pearson's correlation was used to evaluate the correlation between sociodemographic index (SDI) values and the observed trends. In 2019, the ASRs of the incidence, prevalence, mortality and disability-adjusted life years (DALYs) of RHD were 37.39/105 (95%UI, 28.59/105 to 46.74/105), 513.68/105 (95%UI, 405.01/105 to 636.25/105), 3.85/105 (95%UI, 4.29/105 to 3.29/105) and 132.88/105 (95%UI, 115.02/105 to 150.34/105), respectively. From 1990 to 2019, the incidence and prevalence of RHD showed upward trends and the mortality and DALYs showed downward trends. Countries or regions in Africa, South America and South Asia had a greater burden of RHD. The burden of RHD was greater in women, where as men showed more obvious increasing trends in the incidence and prevalence. The incidence of RHD was highest in adolescents, and the prevalence was highest in young and middle-aged. The mortality and DALYs rate associated with RHD increased with age. The EAPCs in the ASRs were negatively correlated with the SDI value. Although the ASRs of mortality and DALYs attributable to RHD are decreasing globally, RHD remains an important public health problem that needs to be addressed urgently, especially in certain low- and middle-income countries and regions. • The higher incidence and prevalence of RHD were concentrated in Africa, South America and South Asia. • The mortality and DALYs rate of RHD were greatest in South Asia and Africa. • In 2019, the burden of RHD was higher in females in global. • From 1990 to 2019, the increasing trends in the incidence and prevalence of RHD were greater in males. • The incidence and prevalence of RHD were higher in young and middle-aged. The mortality and DALYs rate increased with age. [ABSTRACT FROM AUTHOR]

In recent years, changes in climate, land cover, and sociodemographic dynamics have created new challenges in wildfire management. As a result, advanced and integrated approaches in wildfire science have emerged. The objective of our study is to use geospatial analysis to identify strategic responses to wildfires in the Tangier-Tetouan-Al Hoceima (TTA) region, widely reputed to exhibit the most significant incidences of wildfires in Morocco. We adopted a combined approach, using burned area products (Fire_CCI51: 2002–2020) from the Moderate Resolution Imaging Spectroradiometer (MODIS) and active fires from the Fire Information for Resource Management System (FIRMS: 2001–2022) and processing them with spatiotemporal statistical methods: optimized hotspot analysis (OHA) and emerging hotspot analysis (EHA). The main findings indicate that the TTA region recorded an average of 39.78 km2/year of burned areas, mostly located in forests (74%), mainly cork oak and matorral stands (50%). The OHA detected hotspots covering 2081 km2, with 63% concentrated in the provinces of Chefchaouen and Larache. Meanwhile, clusters of EHA extended over 740 km2 and were composed of the oscillating coldspot (OCS) and oscillating hotspot (OHS) patterns at 50% and 30%, respectively. Additionally, an average of 149 fires/year occurred, located mostly in forests (75%), mainly cork oak and matorral stands (61%). The OHA detected active fire hotspots covering 3904 km2, with 60% located in the provinces of Chefchaouen and Larache. Clusters of EHA over 941 km2 were composed of the oscillating hotspot (OHS) and new hotspot (NHS) patterns at 57% and 25%, respectively. The prevalence of the oscillating and new models mirrors, respectively, the substantial fluctuations in wildfires within the region alternating between periods of high and low wildfire activities and the marked increase in fires in recent times, which has occasioned the emergence of novel hotspots. Additionally, we identified six homogeneous wildfire zones to which we assigned three strategic responses: "maintain" (73% of the territory), "monitor and raise awareness" (14% of the territory), and "reinforce" (13% of the territory). These strategies address current wildfire management measures, which include prevention, risk analysis, preparation, intervention, and rehabilitation. To better allocate firefighting resources, strategic responses were classified into four priorities (very high, high, medium, and low). Last, the wildfire zoning and strategic responses were validated using burned areas from 2021 to 2023, and a global scheme was suggested to assess the effectiveness of future wildfire measures. [ABSTRACT FROM AUTHOR]

Global warming causes a temperature rise and alteration of other meteorological variables that directly or indirectly affect human comfort. The wet bulb globe temperature (WBGT) incorporates the effects of multiple meteorological variables to provide a reliable measure of human thermal stress. Despite the large significance of WBGT on public health, studies related to characterization and trends assessment of WBGT are limited in the tropical humid region like Peninsular Malaysia due to the unavailability of all meteorological variables required for such analysis. This study employed reanalysis meteorological data of ERA5 to assess the characteristics and changes in hourly, daily, monthly, seasonal and annual outdoor WBGT over peninsular Malaysia for the period 1959–2021 using the Liljegren method. The WBGT values were classified into five categories to assess the human thermal stress levels defined by the United States Department of the Army (USDA). The mean daily WBGT in PM varies from 21.5 °C in the central south elevated region to 30.5 °C in the western coastal region. It always reaches a heat-related illness risk level (31.20 °C) in the afternoon during monsoon and extreme stress conditions during inter-monsoonal periods. The trend analysis revealed an increase in WBGT for all the time scales. The higher increase in the mean and maximum WBGT was estimated in the coastal and south regions, nearly by 0.10 to 0.25 °C/decade. The increase in mean nighttime WBGT was 0.24 °C/decade, while in mean daytime WBGT was 0.11 °C/decade. The increase in WBGT caused a gradual expansion of areas experiencing daily WBGT exceeding a high-risk level for 5 h (11 AM to 3 PM). The information and maps generated in this study can be used for mitigation planning of heat-related stress risk in PM, where temperature extremes have grown rapidly in recent years. [ABSTRACT FROM AUTHOR]

In the north of Morocco, forest areas are under threat mainly due to the expansion of agricultural land, forest fires and socio-demographic, economic and urban dynamics. Despite the magnitude of deforestation in this area, quantitative studies and investigations of its evolution in time and space are rare or non-existent. The present study aims to assess and quantify gross forest losses in the Western Rif between 2001 and 2020 through the exploitation of Global Forest Change (GFC) data developed by Hansen et al. (version 1.8) based on high resolution Landsat TM satellite images. We used Local Indicators of Spatial Association (LISA) methods to identify statistically significant spatio-temporal trends in forest losses with ArcGis 10.8 and Geoda software. The main results showed that over the last two decades, the Western Rif has lost 8.39% of its forest heritage, a total area of 272 km2. The greatest forest losses were recorded in the provinces of Chefchaouen, Tetouan and Larache (70% of total losses), while the highest annual deforestation rates are reported in the prefectures of M'diq-Fnideq and Tangier-Assilah (0.9% and 0.89% respectively). Moreover, we observed that 81% of the deforested areas were recorded in the formations of the following types: matorral, cork oak stands and artificial pine forest. A first analysis of local Moran's spatial autocorrelation based on the communal division and on the variables relating to forest losses and gross deforestation rates revealed the existence of 3 significant clusters of the high-high (HH) type. A second optimized analysis of deforestation hotspot (Getis-Ord statistical test) based on a 0.5 km × 0.5 km grid identified 26 deforestation fronts in the study area. Finally, we conducted an emerging hotspot analysis to take into account the time dimension and we concluded that the oscillating deforestation model predominates in the Western Rif. These results constitute valuable decision elements to better guide, prioritize and rationalize the monitoring, conservation and restoration efforts of forest ecosystems.

Abstract Background Understanding the trends and causes to the burden of maternal deaths is a key requirement to further reduce the maternal mortality ratio (MMR), and devise targeted intervention policy. We aimed to evaluate the spatiotemporal trends of MMRs and cause patterns across the 34 provinces of China during 1990–2017. Methods Using data from the Global Burden of Disease Study 2017, we calculated the levels and trends of total maternal deaths and MMR due to ten different causes through Bayesian multivariable regression model for pregnancies aged 10–54 years, and assessed the age and regional distribution over time. Results China has experienced fast decline in MMR, dropped from 95.2 (87.8–102.3) in 1990 to 13.6 (12.5–15.0) in 2017, with an annualised rate of decline of 7.0%. In 1990, the range of MMRs in mainland China was 31.1 in Shanghai, to 323.4 in Tibet. Almost all provinces showed remarkable decline in the last two decades. However, spatial heterogeneity in levels and trends still existed. The annualised rate of decline across provinces from 1990 to 2017 ranged from 0.54% to 10.14%. Decline accelerated between 2005 and 2017 compared with between 1990 and 2005. In 2017, the lowest MMR was 4.2 in Zhejiang; the highest was still in Tibet, but had fallen to 82.7, dropped by 74.4%. MMR was highest in the 40–49 years age group in both 1990 and 2017. In 2017, haemorrhage and hypertensive disorders were the leading two specific causes for maternal deaths. Conclusions MMRs have declined rapidly and universally across the provinces of China. Setting of associated interventions in the future will need careful consideration of provinces that still have MMR significantly higher than the national mean level.

Abstract Background Silicosis, as an important type of pneumoconiosis, leads to progressive and irreversible conditions from the beginning of inflammation and fibrosis. However, the data on the global burden of silicosis and long-term trends were limited. Methods Derived from the Global Burden of Disease study 2019 (online publicly available: Global Health Data Exchange), data on both crude and age-standardized rates (ASR) per 100,00 people of mortality and disability-adjusted life years (DALYs) due to silicosis was collected and analyzed. The burden and trends of mortality and DALYs due to silicosis was assessed by 204 countries and territories, by 5-year interval of age group and by sex from 1990 to 2019. And all the regions were divided into 5 categories according to Sociodemographic Index (SDI). Temporal trends in mortality and DALY were evaluated only to ASR by the Joinpoint regression model. Results More than 12.9 thousand [95% Uncertainty Intervals (UI): 10.9, 16.2] death cases occurred due to silicosis worldwide, and 655.7 thousand (95% UI: 519.3, 828.0) DALYs were attributed to silicosis in 2019. From 1990 to 2019, global number of mortality and DALYs in countries with high SDI quintile decreased by 0.35% (95% UI: − 0.45, − 0.17) and 0.32% (95% UI: − 0.45, − 0.01), respectively. There was a greater burden in low- and middle-income countries were estimated in 2019 according to ASRs. The global number of mortality and DALYs among males accounted for over 95% of all in 2019. Both age-sex-specific mortality and DALY rate were increasing with aging and reached their peak at 85–89 age group. During the past 30 years, ASR of mortality and DALYs showed a decreasing trend with average annual percentage change at -3.0% [95% Confidence Intervals (CI): − 3.2, − 2.9] and − 2.0 (95% CI: − 1.7, − 2.2), respectively. Conclusions Silicosis remains an important health issue and causes a potentially serious burden worldwide. Attention should be paid to making preventable, affordable and effective measures in lower SDI regions.

The seasonal mountain snowpack of the Western US (WUS) is a key water resource to millions of people and an important component of the regional climate system. Impurities at the snow surface can affect snowmelt timing and rate through snow radiative forcing (RF), resulting in earlier streamflow, snow disappearance, and less water availability in dry months. Predicting the locations, timing, and intensity of impurities is challenging, and little is known concerning whether snow RF has changed over recent decades. Here we analyzed the relative magnitude and spatio-temporal variability of snow RF across the WUS at three spatial scales (pixel, watershed, regional) using remotely sensed RF from spatially and temporally complete (STC) MODIS data sets (STC-MODIS Snow Covered Area and Grain Size/MODIS Dust Radiative Forcing on Snow) from 2001 to 2022. To quantify snow RF impacts, we calculated a pixel-integrated metric over each snowmelt season (1st March–30th June) in all 22 years. We tested for long-term trend significance with the Mann–Kendall test and trend magnitude with Theil–Sen’s slope. Mean snow RF was highest in the Upper Colorado region, but notable in less-studied regions, including the Great Basin and Pacific Northwest. Watersheds with high snow RF also tended to have high spatial and temporal variability in RF, and these tended to be near arid regions. Snow RF trends were largely absent; only a small percent of mountain ecoregions (0.03%–8%) had significant trends, and these were typically decreasing trends. All mountain ecoregions exhibited a net decline in snow RF. While the spatial extent of significant RF trends was minimal, we found declining trends most frequently in the Sierra Nevada, North Cascades, and Canadian Rockies, and increasing trends in the Idaho Batholith. This study establishes a two-decade chronology of snow impurities in the WUS, helping inform where and when RF impacts on snowmelt may need to be considered in hydrologic models and regional hydroclimate studies.

Global vegetation greening during recent decades has been observed from various remote sensing data. The global and regional climate can be altered by an increase in carbon storage, as well as changes in land surface albedo (LSA) and evaporation. However, the LSA changes induced by global vegetation greening are still not clear, and contrasting responses of LSA to vegetation changes were reported in previous studies. In this study, we analyzed the LSA in response to global vegetation greening using the Global Land Surface Satellite (GLASS) data and a vegetation-induced LSA change model. The results showed that vegetation greening trends could be observed worldwide, which resulted in contrasting LSA responses at regional scales (LSA increased as leaf area index (LAI) increased, or LSA decreased as LAI increased). Moreover, these contrasting LSA responses to global vegetation greening were effectively explained by the albedo difference between a vegetation and soil background. The results provide new insights into the relationship between LSA changes and global vegetation dynamics, and can support recommendations for policies of vegetation protection, and large-scale afforestation and deforestation. [ABSTRACT FROM AUTHOR]

BackgroundNeonatal mortality rate (NMR), infant mortality rate (IMR), and child mortality rate (CMR) show a huge difference across countries, which has been posing challenges for public health policies and medical resource allocation.MethodsBayesian spatiotemporal model is applied to assess the detailed spatiotemporal evolution of NMR, IMR, and CMR from a global perspective. Panel data from 185 countries from 1990 to 2019 are collected.ResultsThe continuously decreasing trend of NMR, IMR, and CMR indicated a great improvement in neonatal, infant, and child mortality worldwide. Further, huge differences in the NMR, IMR, and CMR still exist across countries. In addition, the gap of NMR, IMR, and CMR across the countries presented a widening trend from the perspective of dispersion degree and kernel densities. The spatiotemporal heterogeneities demonstrated that the decline degree among these three indicators could be observed as CMR > IMR > NMR. Countries such as Brazil, Sweden, Libya, Myanmar, Thailand, Uzbekistan, Greece, and Zimbabwe showed the highest values of b1i, indicating a weaker downward trend compared to the overall downward trend in the world.ConclusionsThis study revealed the spatiotemporal patterns and trends in the levels and improvement of NMR, IMR, and CMR across countries. Further, NMR, IMR, and CMR show a continuously decreasing trend, but the differences in improvement degree present a widening trend across countries. This study provides further implications for policy in newborns, infants, and children's health to reduce health inequality worldwide.

Background This study was conducted to estimate the distribution of and changes in the global disease burden of ischemic heart disease attributable to smoking between 1990 and 2019. Methods and Results Data used in this study come from the GBD 2019 (Global Burden of Disease Study 2019). Age‐standardized rates and estimated annual percentage change of age‐standardized rates were used to describe this burden and its changing trend. Pearson's correlation coefficient was used to evaluate the correlation between the sociodemographic index and changing trend. From 1990 to 2019, the burden of ischemic heart disease attributable to smoking has shown a downward trend globally; estimated annual percentage changes of age‐standardized mortality rates and age‐standardized disability‐adjusted life‐years rates were −2.012 (95% CI, −2.068 to −1.956) and −1.907 (95% CI, −1.975 to −1.838). Nineteen countries experienced an increase in disease burden, and the changes in 17 countries were not statistically significant. In addition, this burden was higher in men and older age groups. Estimated annual percentage change of the age‐standardized rates of this burden were negatively correlated with the sociodemographic index. Conclusions Although the burden of ischemic heart disease attributable to smoking has decreased in >80% of countries or regions in the past 30 years, it has remained a significant issue in low‐ and middle‐income countries, particularly among men and elderly populations. Therefore, active tobacco control measures, focusing on key populations, are required to reduce the associated burden of ischemic heart disease, especially in those countries or regions with increasing prevalence and disease burden.

Background: Understanding the trends and causes to the burden of maternal deaths is a key requirement to further reduce the maternal mortality ratio (MMR), and devise targeted intervention policy. We aimed to evaluate the spatiotemporal trends of MMRs and cause patterns across the 34 provinces of China during 1990-2017.Methods: Using data from the Global Burden of Disease Study 2017, we calculated the levels and trends of total maternal deaths and MMR due to ten different causes through Bayesian multivariable regression model for pregnancies aged 10-54 years, and assessed the age and regional distribution over time.Results: China has experienced fast decline in MMR, dropped from 95.2 (87.8-102.3) in 1990 to 13.6 (12.5-15.0) in 2017, with an annualised rate of decline of 7.0%. In 1990, the range of MMRs in mainland China was 31.1 in Shanghai, to 323.4 in Tibet. Almost all provinces showed remarkable decline in the last two decades. However, spatial heterogeneity in levels and trends still existed. The annualised rate of decline across provinces from 1990 to 2017 ranged from 0.54% to 10.14%. Decline accelerated between 2005 and 2017 compared with between 1990 and 2005. In 2017, the lowest MMR was 4.2 in Zhejiang; the highest was still in Tibet, but had fallen to 82.7, dropped by 74.4%. MMR was highest in the 40-49 years age group in both 1990 and 2017. In 2017, haemorrhage and hypertensive disorders were the leading two specific causes for maternal deaths.Conclusions: MMRs have declined rapidly and universally across the provinces of China. Setting of associated interventions in the future will need careful consideration of provinces that still have MMR significantly higher than the national mean level. [ABSTRACT FROM AUTHOR]

Background: Silicosis, as an important type of pneumoconiosis, leads to progressive and irreversible conditions from the beginning of inflammation and fibrosis. However, the data on the global burden of silicosis and long-term trends were limited.Methods: Derived from the Global Burden of Disease study 2019 (online publicly available: Global Health Data Exchange), data on both crude and age-standardized rates (ASR) per 100,00 people of mortality and disability-adjusted life years (DALYs) due to silicosis was collected and analyzed. The burden and trends of mortality and DALYs due to silicosis was assessed by 204 countries and territories, by 5-year interval of age group and by sex from 1990 to 2019. And all the regions were divided into 5 categories according to Sociodemographic Index (SDI). Temporal trends in mortality and DALY were evaluated only to ASR by the Joinpoint regression model.Results: More than 12.9 thousand [95% Uncertainty Intervals (UI): 10.9, 16.2] death cases occurred due to silicosis worldwide, and 655.7 thousand (95% UI: 519.3, 828.0) DALYs were attributed to silicosis in 2019. From 1990 to 2019, global number of mortality and DALYs in countries with high SDI quintile decreased by 0.35% (95% UI: - 0.45, - 0.17) and 0.32% (95% UI: - 0.45, - 0.01), respectively. There was a greater burden in low- and middle-income countries were estimated in 2019 according to ASRs. The global number of mortality and DALYs among males accounted for over 95% of all in 2019. Both age-sex-specific mortality and DALY rate were increasing with aging and reached their peak at 85-89 age group. During the past 30 years, ASR of mortality and DALYs showed a decreasing trend with average annual percentage change at -3.0% [95% Confidence Intervals (CI): - 3.2, - 2.9] and - 2.0 (95% CI: - 1.7, - 2.2), respectively.Conclusions: Silicosis remains an important health issue and causes a potentially serious burden worldwide. Attention should be paid to making preventable, affordable and effective measures in lower SDI regions. [ABSTRACT FROM AUTHOR]

Background: Exposure to ambient particulate matter pollution (APMP) is a global health issue that directly affects the human respiratory system. Thus, we estimated the spatiotemporal trends in the burden of APMP-related respiratory diseases from 1990 to 2019.Methods: Based on the Global Burden of Disease Study 2019, data on the burden of APMP-related respiratory diseases were analyzed by age, sex, cause, and location. Joinpoint regression analysis was used to analyze the temporal trends in the burden of different respiratory diseases over the 30 years.Results: Globally, in 2019, APMP contributed the most to chronic obstructive pulmonary disease (COPD), with 695.1 thousand deaths and 15.4 million disability-adjusted life years (DALYs); however, the corresponding age-standardized death and DALY rates declined from 1990 to 2019. Similarly, although age-standardized death and DALY rates since 1990 decreased by 24% and 40%, respectively, lower respiratory infections (LRIs) still had the second highest number of deaths and DALYs attributable to APMP. This was followed by tracheal, bronchus, and lung (TBL) cancer, which showed increased age-standardized death and DALY rates during the past 30 years and reached 3.78 deaths per 100,000 persons and 84.22 DALYs per 100,000 persons in 2019. Among children aged < 5 years, LRIs had a huge burden attributable to APMP, whereas for older people, COPD was the leading cause of death and DALYs attributable to APMP. The APMP-related burdens of LRIs and COPD were relatively higher among countries with low and low-middle socio-demographic index (SDI), while countries with high-middle SDI showed the highest burden of TBL cancer attributable to APMP.Conclusions: APMP contributed substantially to the global burden of respiratory diseases, posing a significant threat to human health. Effective actions aimed at air pollution can potentially avoid an increase in the PM2.5-associated disease burden, especially in highly polluted areas.

It is of great practical significance to thoroughly study the environmental changes and conduct desertification assessments of sandy lands to elucidate the formation and recovery mechanism of desertification. The purpose of this study is to evaluate the desertification process and its driving factors accurately and objectively, and compare the differences of desertification process in different areas. We used Moderate Resolution Imaging Spectroradiometer (MODIS) surface albedo (MCD43A3) and leaf area index (LAI) (MCD15A2H) products to calculate the desertification divided index (DDI) to reveal the spatial-temporal variation regularity of the four sandy lands in northern China during 2000–2017 as well as the correlation between desertification and precipitation. The results showed that the total desertification degree of sandy lands in northern China showed a downward trend during the study period. By grading the desertification level, it was found the decline trend of severe desertification and high desertification was relatively significant (p < 0.05). The spatial trend of the desertification level in sandy lands was significantly different, and the decreased area of severe desertification and high desertification in Mu Us sandy land was the largest (−0.042 × 104 km2 yr−1 and −0.052 × 104 km2 yr−1), while the interannual variation of the various desertification levels in Hulun Buir sandy land was small (±0.003 × 104 km2 yr−1). The precipitation and DDI were positively correlated in most areas (p < 0.05). Especially in Mu Us sandy land and Hunshandake sandy land, the proportional area of positive correlation between the precipitation and DDI was more prominent, accounting for 72.9% and 63.7%, respectively. This study had important decision-making significance for the effective management of sandy lands in arid/semiarid areas. [ABSTRACT FROM AUTHOR]

Temporal and spatial variability of per- and polyfluoroalkyl substances (PFASs) in herring, cod, eelpout, and guillemot covering four decades and more than 1000 km in the Baltic Sea was investigated to evaluate the effect of PFAS regulations and residence times of PFASs. Overall, PFAS concentrations responded rapidly to recent regulations but with some notable basin- and homologue-specific variability. The well-ventilated Kattegat and Bothnian Bay showed a faster log-linear decrease for most PFASs than the Baltic Proper, which lacks a significant loss mechanism. PFOS and FOSA, for example, have decreased with 0-7% y -1 in the Baltic Proper and 6-16% y -1 in other basins. PFNA and partly PFOA are exceptions and continue to show stagnant or increasing concentrations. Further, we found that Bothnian Bay herring contained the highest concentrations of >C 12 perfluoroalkyl carboxylic acids (PFCAs), likely from rivers with high loads of dissolved organic carbon. In the Kattegat, low PFAS concentrations, but a high FOSA fraction, could be due to influence from the North Sea inflow below the halocline and possibly a local source of FOSA and/or isomer-specific biotransformation. This study represents the most comprehensive spatial and temporal investigation of PFASs in Baltic wildlife while providing new insights into cycling of PFASs within the Baltic Sea ecosystem.

Abstract Background Leptospirosis morbidity and mortality rates in China have decreased since the 2000s. Further analyses of the spatiotemporal and demographic changes occurring in the last decade and its implication on estimates of disease burden are required to inform intervention strategies. In this study, we quantified the epidemiological shift and geographical heterogeneity in the burden of leptospirosis during 2005–2015 in China. Methods We used reported leptospirosis case data from 1st January 2005 to 31st of December 2015 that routinely collected by the China Information System for Disease Control and Prevention (CISDCP) to analyze the epidemiological trend and estimate the burden in terms of disability-adjusted life-years (DALYs) over space, time, and demographical groups. Results A total of 7763 cases were reported during 2005–2015. Of which, 2403 (31%) cases were the laboratory-confirmed case. Since 2005, the notified incidence rate was gradually decreased (P 0.05). During 2005–2015, we estimated a total of 10 313 DALYs were lost due to leptospirosis comprising a total of 1804 years-lived with disability (YLDs) and 8509 years-life lost (YLLs). Males had the highest burden of disease (7149 DALYs) compared to females (3164 DALYs). The highest burden estimate was attributed to younger individuals aged 10–19 years who lived in southern provinces of China. During 2005–2015, this age group contributed to approximately 3078 DALYs corresponding to 30% of the total DALYs lost in China. Yet, our analysis indicated a declining trend in burden estimates (P

Concurrent regional precipitation can cause water disasters and have an enormous impact on the environment and society. In the present study, regional precipitation events (RPEs) were computed using daily precipitation records from 1989 to 2018 recorded at 173 meteorological stations in the Beijing–Tianjin–Hebei (Jing‐Jin‐Ji) region. This region is famous for its political and economic status and suffers from numerous water disasters. When more than 5% of stations record over 20 mm precipitation on a specific day, it is termed as an RPE. This study describes the duration, intensity, and coverage area of RPEs in the Jing‐Jin‐Ji region. Moreover, it analyses the region's long‐term spatiotemporal evolution of RPEs to explore more complete precipitation characteristics over the study region. The results reveal that the frequency of RPEs decreased with longer duration, and most RPEs with a rainfall intensity of approximately 10 mm⋅day−1 or covered more than 90% of the stations. The coverage area was positively correlated with duration and intensity. RPEs mainly occurred from June to August, with the average ratio of RPEs' total wet day precipitation (PRCPTOT) to regional PRCPTOT being 0.72. The contribution of RPEs to regional annual precipitation increased significantly after 1997. During the past 30 years, the number of RPEs initially decreased and then increased significantly. During strong El Niño decaying summers, the frequency of RPEs was much higher. The spatial distribution of RPEs was affected by topography, land, and sea locations, with greater frequency in the coastal plains. Approximately 28.8% of the RPEs were accompanied by housing losses, which were highly prone to catastrophe compared to extreme precipitation at individual stations. These findings have the potential to improve evaluations of the impacts of water disasters. [ABSTRACT FROM AUTHOR]

The aim of this study was to explore Leishmania infantum epidemiology through a One Health approach that promotes a better estimation of leishmaniasis burden and a deeper understanding of the spatial distribution of the key actors of the parasite life cycle (vectors, reservoirs and humans). We conducted a 14‐year mixed retrospective and prospective study of leishmaniasis cases in an endemic area in southern Spain (Granada province), to estimate the human incidence and its association with the vector presence, cryptic leishmaniasis rates and canine leishmaniasis prevalence. We found an annual linear increase in the incidence that cannot be fully explained by active case surveillance and the improvement of PCR diagnostic techniques. 49.4% of cases were not reported to the surveillance system. Approximately half of the human cases correspond to the visceral form that occurred more frequently in men; cutaneous, mucosal and cryptic forms were also detected. Leishmaniasis is no longer a disease of young children, accounting for a quarter of immunocompetent patients and most infected people remained asymptomatic. Human and canine leishmaniasis, cryptic or symptomatic, are present in the whole province, where there is a medium/high risk of the presence of Phlebotomus perniciosus, the main vector. We found association between the incidence of human leishmaniasis and the presence of the vector, but not with the prevalence of canine leishmaniasis and cryptic human leishmaniasis. A potential hot spot was also found, where high leishmaniasis incidence may be associated to the involvement of host species other than dogs. [ABSTRACT FROM AUTHOR]

The study analysed the spatiotemporal variation in extreme precipitation and temperature at the daily scale across India using eight indices of climate change suggested by the Expert Team on Climate Change Detection and Indices (ETCCDI). For this analysis, latest high-resolution India Meteorological Department (IMD) data for the period 1971–2017 (precipitation) and 1971–2013 (temperature) are used along with global gridded reanalysis products. The trends are evaluated using non-parametric Mann-Kendall (MK) test and regression analysis. At the annual scale, about 13% of the locations indicated significant trend (either increasing or decreasing at 5% significance level) in the index R95p (rainfall contribution from extreme 'wet days') while 20% of the locations indicated significant trend in R5p (rainfall contribution from extreme 'dry days'). For the seasonal analysis (June to September), the corresponding figures are nil and 21% respectively. The number of 'warm days' per year increased significantly at 14% of the locations, while the number of 'cold days', 'warm nights' and 'cold nights' per year decreased significantly at several (42%, 34% and 39%) of the locations. The extreme temperature indices for the future (using CanESM2 projected data for RCP8.5 after suitable bias correction) show significant increasing (decreasing) trend in warm days (cold days) in most (49% to 84%) of the locations. Further, most locations (varying from 60 to 81%) show an increasing trend in warm nights and a decreasing trend in cold nights. Similar analysis for the historical and future period are also performed using Climate Prediction Centre (CPC) reanalysis data as the reference and the trends, on comparison with IMD data, seem to be in agreement for temperature extremes but spatially more extensive in case of CPC precipitation extremes. [ABSTRACT FROM AUTHOR]

China's commitment to attaining carbon neutrality by 2060 has galvanized research into carbon sequestration, a critical approach for mitigating climate change. Despite the rapid urbanization observed since the turn of the millennium, a comprehensive analysis of how urbanization influences urban carbon storage throughout China remains elusive. Our investigation delves into the nuanced effects of urbanization on carbon storage, dissecting both the direct and indirect influences by considering urban-suburban gradients and varying degrees of urban intensity. We particularly scrutinize the roles of climatic and anthropogenic factors in mediating the indirect effects of urbanization on carbon storage. Our findings reveal that urbanization in China has precipitated a direct reduction in carbon storage by approximately 13.89 Tg of carbon (Tg C). Remarkably, urban sprawl has led to a diminution of vegetation carbon storage by 8.65 Tg C and a decrease in soil carbon storage by 5.24 Tg C, the latter resulting from the sequestration of impervious surfaces and the elimination of organic matter inputs following vegetation removal. Meanwhile, carbon storage in urban greenspaces has exhibited an increase of 6.90 Tg C and offsetting 49.70% of the carbon loss induced by direct urbanization effects. However, the indirect effects of urbanization predominantly diminish carbon storage in urban greenspaces by an average of 5.40%. The degree of urban vegetation management emerges as a pivotal factor influencing the indirect effects of urbanization on carbon storage. To bolster urban carbon storage, curbing urban sprawl and augmenting urban green spaces are imperative strategies. Insights from this study are instrumental in steering sustainable urban planning and advancing towards the goal of carbon neutrality. [Display omitted] • - Analyzed 30 m resolution urban carbon storage changes from 2000 to 2020. • - Evaluated direct and indirect urbanization impacts on carbon storage. • - Identified a direct urban expansion carbon loss of 13.89 Tg. • - Noted a 6.90 Tg C increase in urban greenspaces, mitigating 49.70% of the loss. • - −5.40% indirect effect on greenspaces, aggravating decline in carbon storage. [ABSTRACT FROM AUTHOR]

Air pollution in the form of particulate matter (PM) is becoming one of the greatest current threats to human health on a global scale. This paper firstly presents a Bayesian space–time hierarch piecewise regression model (BSTHPRM) which can self-adaptively detect the transitions of local trends, accounting for spatial correlations. The spatiotemporal trends of the approximately anthropogenic PM 2.5 removed natural dust (PM 2.5_No Dust) concentrations and the corresponding population's PM 2.5_No Dust exposure (PPM 2.5 E) in the global continent from 1998 to 2016 were investigated by the presented BSTHPRM. The total areas of the high and higher PM 2.5_No Dust -polluted regions, whose spatial relative magnitude of PM 2.5_NoDust pollution to the global continental overall level was between 1.89 and 14.68, accounted for about 13.4% of the global land area, and the corresponding exposed populations accounted for 56.0% of the global total population. The spatial heterogeneity of the global PM 2.5_NoDust pollution increased generally from 1998 to 2016. The areas of hot, warm, and cold spots with increasing trends of PM 2.5_NoDust concentration initially contracted and then later expanded. The local trends of the global continental PM 2.5_NoDust concentrations and PPM 2.5 E can be parted into three changing stages, early, medium, and later stages, using the BSTHPRM. The area proportions of the regions experiencing a decreasing trend of PM 2.5_NoDust concentrations and PPM 2.5 E were greater in the medium stage than in the early and later stages. The local trends of PM 2.5_NoDust concentration and PPM 2.5 E in the two higher PM 2.5_NoDust polluted areas, northern India and eastern and southern China, increased in the early stage and then decreased in the medium stage. In the later stage (recent years), northern India displayed a stronger increasing trend; nevertheless, the follow-up decreasing trend still occurred in eastern and southern China. In the first two stages, more than half of the areas in Europe experienced a decreasing trend of PM 2.5_NoDust concentration and PPM 2.5 E; later, more than half of areas in Europe exhibited increasing trends in the later stage. North America and South America experienced a similar local trend of PPM 2.5 E to Europe. The PPM 2.5 E trend in Africa generally increased during the study period. • First presentation of a Bayesian space-time hierarchy piecewise regression model detecting self-adaptively transitions. • Firstly applies a developed Bayesian space-time model in investigating the global population's exposure to PM 2.5. • Deeply analyses the spatiotemporal trends of the global continental PM 2.5 pollution removed natural dust. • Details the spatiotemporal trends of the global population's exposure to anthropogenic PM 2.5. [ABSTRACT FROM AUTHOR]

Abstract Ambient fine particulate matter (PM 2.5) has long been the primary air pollutant with alarming public health risk in China. PM 2.5 pollution control in China still mainly concerned concentration declining. The qualification and identification of PM 2.5 -attributable health loss is crucial for China's air quality improvement and pollution prevention. This study assessed the annual health loss and economic impact attributed to PM 2.5 exposure at a city level in China from 2015 to 2017. The health benefits from achieving specific PM 2.5 concentration control targets were estimated for 2020. The economic value of health loss in China was 3205.05, 3223.51, and 3344.80 billion Yuan in 2015, 2016, and 2017, representing 4.34%, 4.07%, and 3.85% of the gross domestic product of China. The health loss value in Beijing–Tianjin–Hebei (BTH) and surrounding areas and the Yangtze River Delta (YRD) urban agglomeration in 2017 was 731.93 and 520.27 billion Yuan, accounting for 21.88% and 15.56%, respectively, of the total economic value of all assessed cities. The economic value of health loss in provincial cities was high. From 2015 to 2017, high health loss in BTH and surrounding areas showed a diffusion trend toward cities in Henan, Shanxi, and Shaanxi Provinces. High health loss in the YRD urban agglomeration transferred to cities located in the middle and upper reaches of the Yangtze River. If PM 2.5 concentration control targets can be achieved by 2020, premature mortality attributed to PM 2.5 exposure will fall by 91,860 cases, representing 11.20% of which in 2017. This study, for the first time, highlighted the spatial distribution and temporal variation characteristics of health loss in Chinese cities based on ground-monitoring PM 2.5 concentration data and annual real-time population data. Distributional feature and time-trend analysis would provide a measurable assessment of health loss in Chinese cities to policymakers for effective allocating their efforts on air quality improvement. Graphical abstract Economic value of public health loss attributed to PM 2.5 exposure at the city level in 2017. Image 1 Highlights • We assessed the annual health loss and economic impact of PM 2.5 exposure in China. • We used PM 2.5 and population data (2015–2017) of prefecture-level cities or above. • Health loss declined from 0.91 (2015) to 0.82 (2017) million premature mortalities. • Annual economic value of health loss increased but declined as a percent of GDP. • Meeting updated PM 2.5 targets by 2020 could reduce mortality by 11% of 2017 levels. [ABSTRACT FROM AUTHOR]

Abstract Sixteen per - and polyfluoroalkyl substances (PFASs) were measured in liver (n = 52) and kidney (n = 18) tissues of Indo-Pacific humpback dolphins (Sousa chinensis) stranded in the Pearl River Estuary (PRE) of China between 2004 and 2016. The average concentrations of perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA) and most of other PFASs in the liver samples were respectively greater than any records previously reported in cetaceans globally. PFOS levels in 46% of dolphin liver samples exceeded the hepatic toxicity threshold in cetaceans. For the first time, we found a U-shaped trend for the distribution pattern of perfluorinated carboxylic acids (PFCAs) between liver and kidney with increasing carbon chain lengths (C5-C16), whereas a descending trend (C4-C10) was found for perfluoroalkane sulfonic acids (PFASs), which may be explained by binding efficiencies of PFAS analogues to proteins. Dolphins with the highest levels of ∑PFASs (age-corrected) were clustered near the river outlets in Lingdingyang area, which agrees with the spatial distribution of PFASs in the environment. Significant temporal trends were observed for many PFASs. Concentrations of PFOA, perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA) and perfluoroheptanoic acid (PFHpA) all peaked in year 2011, followed by a decreasing trend, while a consistently descending trend was shown for perfluoroundecanoic acid (PFUdA) and perfluorodecane sulfonate (PFDS). Our findings contribute to the knowledge of tissue distribution and spatiotemporal trends of PFASs in the PRE dolphins, which are valuable for us to understand the PFASs exposure risk and their industrial emission in Southern China. Graphical abstract Unlabelled Image Highlights • Median hepatic PFOS and PFOA levels in this study were the highest in cetaceans globally. • Tissue distribution of PFCAs with increasing carbon chain length showed an U-shape trend. • Significant spatiotemporal trends were shown for the levels of many PFASs in dolphins. • Risk assessment suggested that 46% of PFOS concentrations exceeded the Tentative critical concentration. [ABSTRACT FROM AUTHOR]

The spatiotemporal variations of fine particulate matter (PM 2.5) chemical composition have changed over time in the U.S. and increasing evidence indicated differential toxicity of PM 2.5 chemical composition. Thus, comprehensive explanation of PM 2.5 -related adverse health impacts in the U.S. necessitated a detailed analysis of spatiotemporal trends of PM 2.5 chemical composition. This research aims to analyze the changes in concentrations of PM 2.5 and its chemical composition in spatial and temporal scales in the conterminous U.S. The PM 2.5 mass concentration and chemical speciation data were downloaded from U.S. EPA Air Quality System (AQS) (2006–2020) to investigate the spatiotemporal changes of PM 2.5 and its chemical components. The results indicated that national annual average PM 2.5 concentration was significantly reduced from 11.38 ± 2.94 μg m−3 in 2006 to 8.20 ± 2.76 μg m−3 in 2020 with an average reduction of 0.21 μg m−3yr−1, mainly attributed to inorganic PM 2.5 reductions (i.e., ammonium (NH 4 +), nitrate (NO 3 −), and sulfate (SO 4 2−)) and the average reductions were 0.09 μg m−3yr−1, 0.02 μg m−3yr−1, and 0.06 μg m−3yr−1, respectively. The largest air quality improvements occurred in areas with the worst baseline air quality. Moreover, observed spikes in PM 2.5 in California in 2020 were due to higher concentrations of organic matter (OM) and elemental carbon (EC) caused by 2020 wildfires. Furthermore, while levels of SO 4 2−, NO 3 −, and NH 4 + almost levelled off in recent years, further air quality improvements may require targeting carbonaceous species. The heavily polluted days occurred less frequently in recent years and primary organic carbon (OC) accounted for a larger portion of OC in winter than in summer because of the relatively reduced formation rate of secondary organic aerosol (SOA). Our analysis revealed the spatial and temporal trends of various PM 2.5 chemical composition in the conterminous U.S. and provided insights into source contributions, atmospheric chemical conditions, and development of future emissions control strategies. [Display omitted] • Novel spatiotemporal trends analyses focusing on both PM 2.5 and chemical components. • Annual average PM 2.5 concentration was significantly reduced in 2006–2020 in U.S. • Larger air quality improvements occurred in areas with worse baseline air quality. • Spikes in 2020 annual average PM 2.5 in California were likely due to wildfires. • Further air quality improvements may require targeting carbonaceous species. [ABSTRACT FROM AUTHOR]

Complexity analysis is an important tool for research on water resources. Although physical methods and quantitative detection are typically used to explore system complexity, this study uses a method combining probabilistic statistics with nonlinear science. The precipitation concentration index (CI), Mann-Kendall trend testing, probability density functions, and chaotic characteristic quantity are used to assess the spatiotemporal complexity of precipitation in Heilongjiang Province, China. The results show that the annual precipitation in Heilongjiang Province exhibits distinct spatial patterns; the highest values occurred at 128°E, gradually diminishing toward the east and west. Maximum precipitation was recorded at Shangzhi station (646 mm). A negative value of Z, an indicator of a precipitation trend, indicates a decreasing trend and a positive Z value indicates an increasing trend. In Yichun and Shangzhi, areas with greater precipitation, Z values were -1.21 and -4.88, respectively. In contrast, Z values were 3.02 and 0.93 in Qiqihar and Tailai, respectively, areas with lower precipitation. These findings indicate that precipitation differences between different regions have decreased, with the distribution becoming more uniform. Using ArcGIS to determine the chaotic characteristics of daily precipitation, values in the central and northeastern plains were high, whereas those in northwestern mountains were low. Maximum λmax values (3.456 × 10-3), an indicator of the degree of chaos, were obtained at the Yilan and Suifenhe stations, whereas the minimum value (9 × 10-5) was obtained at the Huma station. The authors analyze factors that influence the hydrological cycle in the study region by combining regional population and natural resource conditions. The results of this research will provide a reference for existing research and a theoretical basis for the scientific management of water resources in the region. [ABSTRACT FROM AUTHOR]

Data on spatiotemporal variations in groundwater levels are crucial for understanding arsenic (As) behavior and dynamics in groundwater systems. Little is known about the influences of groundwater extraction on the transport and mobilization of As in the Hetao Basin, Inner Mongolia (China), so groundwater levels were recorded in five monitoring wells from 2011 to 2016 and in 57 irrigation wells and two multilevel wells in 2016. Results showed that groundwater level in the groundwater irrigation area had two troughs each year, induced by extensive groundwater extraction, while groundwater levels in the river-diverted (Yellow River) water irrigation area had two peaks each year, resulting from surface-water irrigation. From 2011 to 2016, groundwater levels in the groundwater irrigation area presented a decreasing trend due to the overextraction. Groundwater samples were taken for geochemical analysis each year in July from 2011 to 2016. Increasing trends were observed in groundwater total dissolved solids (TDS) and As. Owing to the reverse groundwater flow direction, the Shahai Lake acts as a new groundwater recharge source. Lake water had flushed the near-surface sediments, which contain abundant soluble components, and increased groundwater salinity. In addition, groundwater extraction induced strong downward hydraulic gradients, which led to leakage recharge from shallow high-TDS groundwater to the deep semiconfined aquifer. The most plausible explanation for similar variations among As, Fe(II) and total organic carbon (TOC) concentrations is the expected dissimilatory reduction of Fe(III) oxyhydroxides. [ABSTRACT FROM AUTHOR]

Increasingly urban agglomeration, representing a group of cities with a compact spatial organization and close economic links, can rise surface temperature in a continuous area due to decreasing distance between cities. Significant progress has been made in elucidating surface urban heat island intensity (SUHII) of a single city or a few big cities, but the SUHII's patterns remain poorly understood in urban agglomeration regions. Using Aqua/Terra MODIS data over 2010–2015, we examined the SUHII variations and their drivers in Yangtze River Delta Urban Agglomeration (YRDUA) of east China. Instead of using the widely-used suburban/rural areas as references, this study predicted the unaffected reference temperature wall-to-wall from natural forests by a simple planar surface model. Results indicated that urbanization warmed the land surface regardless of urban area size in YRDUA, with the SUHII clearly larger in the day (2.6 ± 0.9 °C) than night (0.7 ± 0.4 °C). The SUHII varied markedly by cities, yet the largest did not happen in the presumed core cities. Also, the SUHII differed greatly in a seasonal cycle, with summer-winter difference of 4.2 ± 0.9 °C and 2.0 ± 0.5 °C in the day and night, respectively. Particularly, cooling effects of urban areas were observed in winter for the majority of cities at night. These spatiotemporal patterns depend strongly on the background climate (precipitation and air temperature), vegetation activity, surface albedo, and population density, with contrast mechanisms during the day and night. Further, we showed that ignoring urban agglomeration effect (using suburban/rural areas as the unaffected references) would lead to large biases of SUHII estimates in terms of magnitude and spatial distribution. Our results emphasize the necessity of considering cities altogether when assessing the urbanization effects on climate in an urban agglomeration area. [ABSTRACT FROM AUTHOR]

Microbes are ubiquitous and often occur in functionally and taxonomically complex communities. Unveiling these community dynamics is one of the main challenges of microbial research. Combining a robust, cost effective and widely used method such as Terminal Restriction Fragment Length Polymorphism (T-RFLP) with a Next Generation Sequencing (NGS) method (Illumina MiSeq), offers a solid alternative for comprehensive assessment of microbial communities. Here, these two methods were combined in a study of complex bacterial and fungal communities in the nest mounds of the ant Formica exsecta, with the aim to assess the degree to which these methods can be used to complement each other. The results show that these methodologies capture similar spatiotemporal variations, as well as corresponding functional and taxonomical detail, of the microbial communities in a challenging medium consisting of soil, decomposing plant litter and an insect inhabitant. Both methods are suitable for the analysis of complex environmental microbial communities, but when combined, they complement each other well and can provide even more robust results. T-RFLP can be trusted to show similar general community patterns as Illumina MiSeq and remains a good option if resources for NGS methods are lacking. [ABSTRACT FROM AUTHOR]

We investigated the levels and trends of the 16 USEPA priority PAHs in the blubber of 37 Indo-Pacific humpback dolphins sampled during the period 2012–2017 from the Pearl River Estuary (PRE), China. Σ 16 PAHs concentrations (17.6–6080 ng g −1 wet weight) were at median level compared to dolphin species worldwide. Humpback dolphins affiliated with the hotspots of PAHs, had significantly higher levels of Σ 16 PAHs than individuals from the other areas in the PRE. Moreover, dolphins stranded on the coast of Lingdingyang are significantly more contaminated by Σ 16 PAHs than those in the West-four region of the PRE, which appears to reflect the heterogeneous distribution of PAHs in the environment. A marked decline in blubber Σ 16 PAHs levels is observed over the studied period, with the control of a range of confounding factors. The trend is strongly and statistically significant ( p  < 0.0001), indicating that the loading of PAHs are gradually being reduced. [ABSTRACT FROM AUTHOR]