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Chronic venous disease (CVD) of the lower extremities is a relevant healthcare problem today. The prevalence of CVD, with the predomination of early stage diseases, particularly among socially-active population, is a crucial factor that allows to plan and effectively implement the novel preventive and treatment schemes. In addition, the pathology is daily faced by doctors of virtually all specialties, and their knowledge and skills determine the course of our common fight against the «disease of civilization». Both Russian and global clinical guidelines for the diagnosis and treatment of CVD describe all aspects of the pathogenesis, treatment approaches and regimens for all stages of the disease. Application of the recent treatment algorithms could allow for a qualitative and adequate therapy for patients with chronic venous disease. Along with surgery, conservative treatment is widely used as a mandatory method of treatment of the pathology.

Chronic venous disease of the lower extremities (CVD) is the most common peripheral vascular pathology found in 2/3 of people under the age of 60. Epidemiological studies conducted over the last decade demonstrate a sustained "rejuvenation" of CVD with the emergence of such previously exotic forms as hormone-dependent phlebopathy, gaming addiction syndrome, etc. A characteristic feature of new types of CVD and their early stages is the fact that pathomorphological changes in the venous bed are dominated by the specific symptoms and syndromes which are managed with phlebotropic medicines. Phlebotropic medicines (FM) represent a heterogeneous group of biologically active substances obtained through processing of vegetable raw materials or chemical synthesis, all of them having the ability to increase venous tone and reduce the severity of the specific symptoms and syndromes. FMs are an integral part of conservative, pathogenetically substantiated treatment of patients with primary chronic venous diseases. Timely and adequate use of vascular tone regulators can successfully eliminate the specific vascular symptoms and syndromes.