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Accumulation of amyloid beta (Aβ) is one of the pathological hallmarks of Alzheimer's disease (AD), which can be visualized using [18F]florbetapir positron emission tomography (PET). The aim of this study was to evaluate various parametric methods and to assess their test-retest (TRT) reliability. Two 90 min dynamic [18F]florbetapir PET scans, including arterial sampling, were acquired (n = 8 AD patient, n = 8 controls). The following parametric methods were used; (reference:cerebellum); Logan and spectral analysis (SA), receptor parametric mapping (RPM), simplified reference tissue model2 (SRTM2), reference Logan (rLogan) and standardized uptake value ratios (SUVr(50–70)). BPND+1, DVR, VT and SUVr were compared with corresponding estimates (VT or DVR) from the plasma input reversible two tissue compartmental (2T4k_VB) model with corresponding TRT values for 90-scan duration. RPM (r 2 = 0.92; slope = 0.91), Logan (r 2 = 0.95; slope = 0.84) and rLogan (r 2 = 0.94; slope = 0.88), and SRTM2 (r 2 = 0.91; slope = 0.83), SA (r 2 = 0.91; slope = 0.88), SUVr (r 2 = 0.84; slope = 1.16) correlated well with their 2T4k_VB counterparts. RPM (controls: 1%, AD: 3%), rLogan (controls: 1%, AD: 3%) and SUVr(50–70) (controls: 3%, AD: 8%) showed an excellent TRT reliability. In conclusion, most parametric methods showed excellent performance for [18F]florbetapir, but RPM and rLogan seem the methods of choice, combining the highest accuracy and best TRT reliability. [ABSTRACT FROM AUTHOR]

The main aim of this study was to determine the test–retest reliability of an experimental functional test battery: Y-balance test (YBT), single-leg countermovement jump (SLCMJ), single-leg hop for distance (SLH), side-hop (SH), speedy-jump (SJ), agility-T (AT), and lower extremity functional test (LEFT). Secondary aims were (1) to determine the mean range for the limb symmetry index (LSI) and (2) to detect significant differences in performance between test–retest sessions. Twenty-two healthy adults (14 males, 8 females; age 23.3 ± 3.9) were tested by the same rater during two different sessions (T1–T2), with a seven-day interval, under the same conditions. Reliability analysis showed good-to-excellent reliability (0.89 < ICC < 0.97; 0.80 < α < 0.98) for the test battery. LSI ranged from 95.9 ± 6.7% (SH-T1) to 104.4 ± 12.5% (SLCMJ-T2). Repeated measures ANOVA detected significant performance differences between sessions in the LEFT (p = 0.009) and for non-dominant sides in the SLH (p = 0.015), SH (p = 0.007), and SJ (p = 0.011). The high reliability of the test battery suggests a potential use in clinical sports practice. The LSI range of ≥95% was proposed as a benchmark for healthy adults. Learning effect seems to have played a crucial role in the T2 improvements of the non-dominant side for hop performances (SLH, SH, SJ) and speed performance (LEFT).

Objective: Although widely used, computerized neurocognitive tests (CNTs) have been criticized because of low reliability and poor sensitivity. A systematic review was published summarizing the reliability of Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) scores; however, this was limited to a single CNT. Expansion of the previous review to include additional CNTs and a meta-analysis is needed. Therefore, our purpose was to analyze reliability data for CNTs using meta-analysis and examine moderating factors that may influence reliability. Data Sources: A systematic literature search (key terms: reliability, computerized neurocognitive test, concussion) of electronic databases (MEDLINE, PubMed, Google Scholar, and SPORTDiscus) was conducted to identify relevant studies. Study Selection: Studies were included if they met all of the following criteria: used a test-retest design, involved at least 1 CNT, provided sufficient statistical data to allow for effect-size calculation, and were published in English. Data Extraction: Two independent reviewers investigated each article to assess inclusion criteria. Eighteen studies involving 2674 participants were retained. Intraclass correlation coefficients were extracted to calculate effect sizes and determine overall reliability. The Fisher Z transformation adjusted for sampling error associated with averaging correlations. Moderator analyses were conducted to evaluate the effects of the length of the test-retest interval, intraclass correlation coefficient model selection, participant demographics, and study design on reliability. Heterogeneity was evaluated using the Cochran Q statistic. Data Synthesis: The proportion of acceptable outcomes was greatest for the Axon Sports CogState Test (75%) and lowest for the ImPACT (25%). Moderator analyses indicated that the type of intraclass correlation coefficient model used significantly influenced effect-size estimates, accounting for 17% of the variation in reliability. Conclusions: The Axon Sports CogState Test, which has a higher proportion of acceptable outcomes and shorter test duration relative to other CNTs, may be a reliable option; however, future studies are needed to compare the diagnostic accuracy of these instruments. [ABSTRACT FROM AUTHOR]

Rodriguez-Munoz, Moreno-Jimenez and Sanz-Vergel, (2015) stated that the relationship between workplace bullying and it's effects on employees' health can be better understood using longitudinal designs since is a long lasting phenomenon. Firstly, the study explores the cross-lagged correlations among workplace bullying, passive coping strategies and strain. Secondly, it tests three mediation models on a sample of 73 Romanian employees who completed the questionnaires in two different moments with a time lag of six months. The cross-lagged correlations showed that being intimidated determined the target to cope through denial and being exposed to person-related bullying determined the victim cope through mental and behavioral disengagement. According to the third mediation model, facing workplace bullying acts through passive coping strategies, increases strain. [ABSTRACT FROM AUTHOR]

BACKGROUND: Portable and cost-effective accelerometers can yield instantaneous results of force, power, and velocity, with minimum set-up time to assess muscle power. However, such devices must also produce both valid and reliable data. OBJECTIVE: The current study assessed the validity and reliability of the Myotest Pro wireless accelerometer (ACC). METHODS: Thirty physically active males performed two squat jump, on two separate sessions. The jump was recorded simultaneously by a force platform and ACC, which was attached to a barbell resting on the subjects' shoulders. Validity was determined using Pearson correlation coefficient (r) and t-test between the maximum force platform (F_{FP}) and ACC (F_{ACC}) force. Between session reliability of F_{ACC}, power (P_{ACC}) and velocity (V_{ACC}) from the ACC were assessed with t-test, intraclass correlation coefficient (ICC), and coefficient of variation (CV). RESULTS: F_{ACC} correlated highly to F_{FP} (r=0.815, p< 0.05), but there was a proportionate ratio bias of 0.81. There was no difference between sessions (p> 0.05) for any variable. High ICCs were found for all variables (F_{ACC} 0.90; P_{ACC} 0.80; V_{ACC} 0.84). Low CV was found for F_{ACC} (2.1%), P_{ACC} (3.3%) and V_{ACC} (3.2%). CONCLUSIONS: ACC is a valid and reliable tool to use for assessing barbell movement, but caution in power data interpretation is needed. [ABSTRACT FROM AUTHOR]

Abstract: The primary aim of this study was to determine the repeatability of caffeine''s ergogenic effects on cycling performance. It was hypothesized that improvements in performance would be similar when caffeine was ingested on 2 separate days. Nine endurance-trained men and women (mean age and maximal oxygen uptake, 27.4 ± 5.9 years and 57.5 ± 3.9 mL kg−1 min−1) initially completed 2 familiarization trials. During 3 subsequent sessions separated by at least 48 hours, the subjects completed a 10-km cycling time trial preceded by ingestion of a drink containing caffeine (5 mg/kg) or placebo. Treatments were ingested using a randomized, single-blind, crossover design, and the subjects were deceived as to the specific content of all drinks. During exercise, heart rate, rating of perceived exertion, and time were recorded every 1.6 km. Repeated-measures analysis of variance was used to compare the differences in variables across distance and treatment. In both caffeine trials, caffeine increased (P = .02) cycling performance by 1.6% and 1.9% vs placebo (16.98 ± 0.96 and 16.92 ± 0.97 minutes with caffeine vs 17.25 ± 0.96 minutes in placebo), and 7 of 9 subjects revealed improved performance. The mean performance improvement in the caffeine trials was similar (P = .35; −0.27 and −0.32 minutes, respectively) across days. Heart rate during exercise was higher (P < .001) with caffeine vs placebo, although the rating of perceived exertion was similar (P = .65). Data reveal that caffeine''s ergogenic effects on cycling performance are repeatable across days, yet some individuals did not exhibit improved performance with caffeine. [Copyright &y& Elsevier]

The main aim of this study was to determine the test–retest reliability of an experimental functional test battery: Y-balance test (YBT), single-leg countermovement jump (SLCMJ), single-leg hop for distance (SLH), side-hop (SH), speedy-jump (SJ), agility-T (AT), and lower extremity functional test (LEFT). Secondary aims were (1) to determine the mean range for the limb symmetry index (LSI) and (2) to detect significant differences in performance between test–retest sessions. Twenty-two healthy adults (14 males, 8 females; age 23.3 ± 3.9) were tested by the same rater during two different sessions (T1–T2), with a seven-day interval, under the same conditions. Reliability analysis showed good-to-excellent reliability (0.89 < ICC < 0.97; 0.80 < α < 0.98) for the test battery. LSI ranged from 95.9 ± 6.7% (SH-T1) to 104.4 ± 12.5% (SLCMJ-T2). Repeated measures ANOVA detected significant performance differences between sessions in the LEFT (p = 0.009) and for non-dominant sides in the SLH (p = 0.015), SH (p = 0.007), and SJ (p = 0.011). The high reliability of the test battery suggests a potential use in clinical sports practice. The LSI range of ≥95% was proposed as a benchmark for healthy adults. Learning effect seems to have played a crucial role in the T2 improvements of the non-dominant side for hop performances (SLH, SH, SJ) and speed performance (LEFT). [ABSTRACT FROM AUTHOR]