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Objective – to evaluate efficacy and safety of “Carmolis” fluid and gel in patients with knee osteoarthritis, as well as the gel efficacy combined with ultraphonophoresis.Materials and methods. The study included 200 patients, who were divided into 2 groups depending on the way of application of “Carmolis” forms. Group 1 included 165 patients with knee osteoarthritis (the main group included 90 patients, the control group – 75 patients), who underwent complex local treatment with 2 “Carmolis” forms. Group 2 included 35 patients (20 people in the main group and 15 in the control one). The main group received phonophoresis with “Carmolis” gel, and the control group received “Carmolis” gel locally on the affected knee joint. Patients’ average age in group 1 was 62,7 ± 8,5 years, the average age in the control group was 61.4 ± 8.7 years, the disease duration was 10.1 ± 4.7 and 9.2 ± 6, 0 years, respectively. In group 2 the average age and disease duration were 60.1 ± 12.8 and 5.7 ± 5.4 years, respectively.At the initial stage 90 patients of the main group 1 were rubbed “Carmolis” fluid locally in the joint followed by massage. After the fluid absorbed completely, “Carmolis” gel was applied, followed by massage. In the comparison group (75 patients), standard therapy was combined only with “Carmolis” fluid applied on the II knee joint.Twenty patients of the main group 2 were treated with phonophoresis combined with “Carmolis” gel. Clinical efficacy was assessed by pain dynamics.Results. Treatment with two “Carmolis” local forms significantly decreased average on moving from 61.8 ± 14.2 to 30.7 ± 14.2 (р

Management of patients with knee osteoarthritis (OA) in the presence of comorbidity causes significant difficulties associated with the limitations of pharmacotherapy.Objective: to evaluate the clinical efficacy of ultraphonophoresis with a hyaluronic acid (HA)-containing gel in patients with knee OA complicated by periarthritis.Patients and methods. The open observational comparative study included 30 patients with a reliable diagnosis of knee OA, who were divided into two groups: 1) 15 patients who had undergone ultraphonophoresis with a HA-containing gel for 10 days (a study group); 2) 15 patients who had received ultraphonophoresis with an intact gel (a control group). To determine the clinical efficiency of HA-containing gel ultraphonophoresis, the investigators conducted a survey of patients and a clinical examination with knee joint palpation to detect synovitis and periarthritis, ultrasonography, and an assessment of initial pain and pain on walking on a 100-mm visual analog scale (VAS) for pain.Results and discussion. HA-containing gel ultraphonophoresis was found to lead to a significant relief from both pain in the knee joints on walking from 50 [40; 50] to 20 [10; 20] mm (p = 0.0003) and from initial pain from 50 [40; 50] to 10 [0; 10] mm VAS (p = 0.0003). Ultrasonography revealed a reduction or even complete disappearance of the local inflammatory process in the anserine bursa from 5.5 [4.5; 6.4] to 0 [0; 3.0] mm (p = 0.0003). There were no statistically significant pre- and postoperative differences in Group 2 patients.Conclusion. HA-containing gel ultraphonophoresis in knee OA with periarthritis was shown to contribute to a significant reduction in knee joint pain and to the resolution of periarthritis.Management of patients with knee osteoarthritis (OA) in the presence of comorbidity causes significant difficulties associated with the limitations of pharmacotherapy.Objective: to evaluate the clinical efficacy of ultraphonophoresis with a hyaluronic acid (HA)-containing gel in patients with knee OA complicated by periarthritis.Patients and methods. The open observational comparative study included 30 patients with a reliable diagnosis of knee OA, who were divided into two groups: 1) 15 patients who had undergone ultraphonophoresis with a HA-containing gel for 10 days (a study group); 2) 15 patients who had received ultraphonophoresis with an intact gel (a control group). To determine the clinical efficiency of HA-containing gel ultraphonophoresis, the investigators conducted a survey of patients and a clinical examination with knee joint palpation to detect synovitis and periarthritis, ultrasonography, and an assessment of initial pain and pain on walking on a 100-mm visual analog scale (VAS) for pain.Results and discussion. HA-containing gel ultraphonophoresis was found to lead to a significant relief from both pain in the knee joints on walking from 50 [40; 50] to 20 [10; 20] mm (p = 0.0003) and from initial pain from 50 [40; 50] to 10 [0; 10] mm VAS (p = 0.0003). Ultrasonography revealed a reduction or even complete disappearance of the local inflammatory process in the anserine bursa from 5.5 [4.5; 6.4] to 0 [0; 3.0] mm (p = 0.0003). There were no statistically significant pre- and postoperative differences in Group 2 patients.Conclusion. HA-containing gel ultraphonophoresis in knee OA with periarthritis was shown to contribute to a significant reduction in knee joint pain and to the resolution of periarthritis.

Complex treatment of aged and old patients ( n = 60) suffering from deforming osteoarthrosis complicated with reactive synovitis in combination with associated pathology of cardiovascular system is studied. Natural antioxidant dicvertase introduced by ultrasonic waves was used. Positive combined action of ultraphonophoresis by dicvertase was revealed which resulted in lowering pain syndrome, increasing motions range in the affected joint, normalizing of immunity status which allows to broaden indications for the treatment of these patients by lowering the risk of development of pathologic response of the organism on the treatment and facilitates lowering drug loading on patients.

This article presents the results of the evaluation of the effectiveness of physiotherapy during the postoperative period following rhinoplastic surgery based on the analysis of the dynamics of the clinical symptoms in 374 patients divided into two groups. The main group was comprised of 286 (86.5%) patients who had undergone the comprehensive postoperative rehabilitation with the use of the chosen physiotherapeutic procedures while the group of comparison consisted of 88 (23.5%) patients treated othrerwise. The method in question included the microcurrent lymphatic drainage, the magneto-laser treatment, and ultraphonophoresis. The data obtained give evidence of the significant differences between the two groups of the patients in terms of reduction of oedema of the nasal and facial soft tissues on days 10-12 and 30-35 after the treatment as well as of subcutaneous hemorrhage and pain in the external nose on days 10-12. These effects were more pronounced in the patients of the main group. The local subcutaneous compaction was documented in both groups (though it was more pronounced in the patients of the comparison group; p<0.05) after the disappearance of the bulk of the swelling approximately on days 10-12. It is concluded that the results of the study confirm the effectiveness of the staged performance of various physiotherapeutic procedures during the postoperative period after rhinoplasty.