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BackgroundIntracranial cavernous hemangiomas (CHs) usually originate from the cerebral and cerebellar hemispheres, while the clinical features and optimum treatment of CHs that originate from atypical locations remain unclear.MethodsWe conducted a retrospective analysis of CHs that originated from the sellar, suprasellar, or parasellar region, the ventricular system, the cerebral falx, or the meninges in patients who underwent surgery from 2009 to 2019 in our department.ResultsIn our study, fourteen patients with pathologically confirmed CHs in uncommon locations (UCHs) were enrolled; 5 were located at the sellar or parasellar region, 3 at the suprasellar region, 3 at the ventricular system, 2 at the cerebral falx, and 1 originated from parietal meninges. The most common symptoms were headache and dizziness (10/14); however, none presented with seizures. All UCHs located in the ventricular systems and 2 of the 3 UCHs located in the suprasellar region manifested as hemorrhagic lesions and shared similar radiological features compared with axial CHs; other locations of UCHs did not have a “popcorn” appearance on T2-weighted image. Nine patients achieved GTR, 2 achieved STR, and 3 achieved PR. Four out of five patients who received incomplete resection underwent adjuvant gamma-knife radiosurgery. During the average follow-up of 71.1 ± 43.3 months, no patient died and one patient encountered recurrence and de novo formation of midbrain CH. Most patients had an excellent KPS score of 90–100 (9 of 14) or a good KPS score of 80 (1 of 14).ConclusionWe suggest that surgery is the optimum therapeutic method for UCHs located at the ventricular system, dura mater, and cerebral falx. Stereotactic radiosurgery plays an important role in the treatment of UCHs located at the sellar or parasellar region and remnant UCHs. Favorable outcomes and lesion control could be achieved by surgery.

Castleman Disease (CD) is a rare benign disorder characterized by abnormal lymphoid tissue growth. It can be classified as unicentric CD (UCD) affecting a single lymph node region or multicentric CD (MCD) involving multiple regions. While UCD typically occurs in the mediastinum, MCD is associated with inflammatory symptoms and abnormal lab findings. We present a case of a young Syrian male with pelvic UCD, exhibiting unusual symptoms. Surgical excision led to complete recovery. A 27-year-old male presented with a well-defined pelvic mass discovered during routine ultrasonography. Symptoms included fever, fatigue, weight loss, and lower extremity numbness. Laboratory analysis revealed lymphocytopenia. Imaging identified a retroperitoneal pelvic mass, raising concerns of lymphoma. Surgical resection confirmed Castleman disease, specifically the hyaline vascular variant, dispelling malignancy concerns. Post-surgery, the patient demonstrated complete recovery, with normalized lymphocyte count and resolution of symptoms, affirming the effectiveness of the treatment. Castleman Disease (CD) is characterized by abnormal lymphoid tissue growth. It presents as Unicentric (UCD) or Multicentric (MCD) forms. UCD cases are usually asymptomatic or show compressive symptoms due to mass effect, while MCD is associated with systemic symptoms. The estimated UCD incidence is 16 cases per million person-years, with median age at diagnosis around 30–34 years. Histologically, UCD is categorized into hyaline vascular (HV) and plasma cell (PC) variants. In this case, systemic symptoms and lymphocytopenia deviated from typical UCD presentation, leading to initial lymphoma suspicions. Surgical intervention facilitated recovery without adjuvant therapies. This study emphasizes the spectrum of Castleman Disease (CD) manifestations, distinguishing Unicentric (UCD) and Multicentric (MCD) forms crucial for accurate management. It highlights atypical pelvic UCD presentation and successful surgical treatment's importance. • A young male presented with pelvic unicentric Castleman Disease (UCD) showcasing systemic symptoms and lymphocytopenia, challenging conventional diagnostic expectations. • Resection of the pelvic mass led to complete recovery, affirming the efficacy of surgical intervention in UCD. • Post-surgery confirmation of hyaline vascular Castleman Disease dispelled initial malignancy concerns, highlighting the significance of histopathological analysis in diagnosis. • Management involved intricate surgical challenges and subsequent recovery, emphasizing the need for multidisciplinary care in rare clinical entities. • This case contributes valuable insights into the diverse presentations and tailored treatment modalities for Castleman Disease, particularly in unconventional anatomical sites like the pelvis, enriching the existing medical literature. [ABSTRACT FROM AUTHOR]

Gliosarcomas are uncommon variants of glioblastoma bearing the histological hallmark of two distinct tumor components (high grade glial and sarcomatous). They share similarities with glioblastomas as far as clinico-epidemiological and prognostic factors are concerned. They are commonly cortically-surfacing lesions occurring mostly in the supratentorial compartment. Intraventricular location of a gliosarcoma is very uncommon and reported only once before. We report one such case where the lesion was subependymal and protruded into the ventricle giving the appearance of a truly intraventricluar tumor. We discuss this case and review the relevant literature. [ABSTRACT FROM AUTHOR]

Objective: To report a case of uncommon endometriosis located in the Nuck’s duct and its laparoscopic resolution. Design: Case report. Setting: Gynecologic department at 12 de Octubre University Hospital, Madrid. Patient(s): A 35-year-old woman, gravida 1 para 1, presented with an inguinal right mass. She had a right nephrectomy because of acute pyelonephritis. Computed tomography showed a cystic lesion that was suggestive of a Nuck’s duct cyst. Fine-needle aspiration cytology was performed, and endometriosis was determined. Intervention(s): Cyst removal and closure of the internal inguinal ring’s defect by the laparoscopic approach. Main Outcome Measure(s): Disease free. Result(s): The intervention was successfully performed by laparoscopic approach. The postoperative evolution was good, and the patient was discharged 2 days after surgery. Conclusion(s): Inguinal or Nuck’s duct are both uncommon locations for endometriosis; therefore, it is difficult to suspect in patients without a surgical history. Once identified, the treatment involves removal of the endometrioma and repair of the internal inguinal ring. A laparoscopic approach should be considered when possible. [Copyright &y& Elsevier]